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Items: 1 to 50 of 526

1.

Correction: iPSC-derived homogeneous populations of developing schizophrenia cortical interneurons have compromised mitochondrial function.

Ni P, Noh H, Park GH, Shao Z, Guan Y, Park JM, Yu S, Park JS, Coyle JT, Weinberger DR, Straub RE, Cohen BM, McPhie DL, Yin C, Huang W, Kim HY, Chung S.

Mol Psychiatry. 2019 Jul 31. doi: 10.1038/s41380-019-0467-4. [Epub ahead of print]

PMID:
31366918
2.

Targeted Treatment of Individuals With Psychosis Carrying a Copy Number Variant Containing a Genomic Triplication of the Glycine Decarboxylase Gene.

Bodkin JA, Coleman MJ, Godfrey LJ, Carvalho CMB, Morgan CJ, Suckow RF, Anderson T, Öngür D, Kaufman MJ, Lewandowski KE, Siegel AJ, Waldstreicher E, Grochowski CM, Javitt DC, Rujescu D, Hebbring S, Weinshilboum R, Rodriguez SB, Kirchhoff C, Visscher T, Vuckovic A, Fialkowski A, McCarthy S, Malhotra D, Sebat J, Goff DC, Hudson JI, Lupski JR, Coyle JT, Rudolph U, Levy DL.

Biol Psychiatry. 2019 Oct 1;86(7):523-535. doi: 10.1016/j.biopsych.2019.04.031. Epub 2019 May 9.

PMID:
31279534
3.

Neurotoxic astrocytes express the d-serine synthesizing enzyme, serine racemase, in Alzheimer's disease.

Balu DT, Pantazopoulos H, Huang CCY, Muszynski K, Harvey TL, Uno Y, Rorabaugh JM, Galloway CR, Botz-Zapp C, Berretta S, Weinshenker D, Coyle JT.

Neurobiol Dis. 2019 Oct;130:104511. doi: 10.1016/j.nbd.2019.104511. Epub 2019 Jun 15.

PMID:
31212068
4.

iPSC-derived homogeneous populations of developing schizophrenia cortical interneurons have compromised mitochondrial function.

Ni P, Noh H, Park GH, Shao Z, Guan Y, Park JM, Yu S, Park JS, Coyle JT, Weinberger DR, Straub RE, Cohen BM, McPhie DL, Yin C, Huang W, Kim HY, Chung S.

Mol Psychiatry. 2019 Apr 24. doi: 10.1038/s41380-019-0423-3. [Epub ahead of print] Erratum in: Mol Psychiatry. 2019 Jul 31;:.

5.

Glutamate hypothesis in schizophrenia.

Uno Y, Coyle JT.

Psychiatry Clin Neurosci. 2019 May;73(5):204-215. doi: 10.1111/pcn.12823. Epub 2019 Mar 6. Review.

PMID:
30666759
6.

Dysregulated protocadherin-pathway activity as an intrinsic defect in induced pluripotent stem cell-derived cortical interneurons from subjects with schizophrenia.

Shao Z, Noh H, Bin Kim W, Ni P, Nguyen C, Cote SE, Noyes E, Zhao J, Parsons T, Park JM, Zheng K, Park JJ, Coyle JT, Weinberger DR, Straub RE, Berman KF, Apud J, Ongur D, Cohen BM, McPhie DL, Rapoport JL, Perlis RH, Lanz TA, Xi HS, Yin C, Huang W, Hirayama T, Fukuda E, Yagi T, Ghosh S, Eggan KC, Kim HY, Eisenberg LM, Moghadam AA, Stanton PK, Cho JH, Chung S.

Nat Neurosci. 2019 Feb;22(2):229-242. doi: 10.1038/s41593-018-0313-z. Epub 2019 Jan 21.

7.

Investigating brain d-serine: Advocacy for good practices.

Mothet JP, Billard JM, Pollegioni L, Coyle JT, Sweedler JV.

Acta Physiol (Oxf). 2019 May;226(1):e13257. doi: 10.1111/apha.13257. Epub 2019 Feb 14. Review.

PMID:
30650253
8.

Dysbindin-1 contributes to prefrontal cortical dendritic arbor pathology in schizophrenia.

Konopaske GT, Balu DT, Presti KT, Chan G, Benes FM, Coyle JT.

Schizophr Res. 2018 Nov;201:270-277. doi: 10.1016/j.schres.2018.04.042. Epub 2018 May 11.

9.

The Role of Serine Racemase in the Pathophysiology of Brain Disorders.

Coyle JT, Balu DT.

Adv Pharmacol. 2018;82:35-56. doi: 10.1016/bs.apha.2017.10.002. Epub 2017 Nov 29. Review.

10.

Astrocytes in primary cultures express serine racemase, synthesize d-serine and acquire A1 reactive astrocyte features.

Li S, Uno Y, Rudolph U, Cobb J, Liu J, Anderson T, Levy D, Balu DT, Coyle JT.

Biochem Pharmacol. 2018 May;151:245-251. doi: 10.1016/j.bcp.2017.12.023. Epub 2018 Jan 3.

11.

Altered CREB Binding to Activity-Dependent Genes in Serine Racemase Deficient Mice, a Mouse Model of Schizophrenia.

Balu DT, Coyle JT.

ACS Chem Neurosci. 2018 Sep 19;9(9):2205-2209. doi: 10.1021/acschemneuro.7b00404. Epub 2017 Nov 27.

12.

N-Methyl-d-aspartate receptor co-agonist availability affects behavioral and neurochemical responses to cocaine: insights into comorbid schizophrenia and substance abuse.

Puhl MD, Desai RI, Takagi S, Presti KT, Doyle MR, Donahue RJ, Landino SM, Bergman J, Carlezon WA Jr, Coyle JT.

Addict Biol. 2019 Jan;24(1):40-50. doi: 10.1111/adb.12577. Epub 2017 Nov 23.

PMID:
29168271
13.

Location matters: distinct DNA methylation patterns in GABAergic interneuronal populations from separate microcircuits within the human hippocampus.

Ruzicka WB, Subburaju S, Coyle JT, Benes FM.

Hum Mol Genet. 2018 Jan 15;27(2):254-265. doi: 10.1093/hmg/ddx395.

14.

In Vivo Brain Glycine and Glutamate Concentrations in Patients With First-Episode Psychosis Measured by Echo Time-Averaged Proton Magnetic Resonance Spectroscopy at 4T.

Kim SY, Kaufman MJ, Cohen BM, Jensen JE, Coyle JT, Du F, Öngür D.

Biol Psychiatry. 2018 Mar 15;83(6):484-491. doi: 10.1016/j.biopsych.2017.08.022. Epub 2017 Sep 7.

15.

Serine Racemase and D-serine in the Amygdala Are Dynamically Involved in Fear Learning.

Balu DT, Presti KT, Huang CCY, Muszynski K, Radzishevsky I, Wolosker H, Guffanti G, Ressler KJ, Coyle JT.

Biol Psychiatry. 2018 Feb 1;83(3):273-283. doi: 10.1016/j.biopsych.2017.08.012. Epub 2017 Aug 26.

16.

Astroglial Versus Neuronal D-Serine: Check Your Controls!

Wolosker H, Balu DT, Coyle JT.

Trends Neurosci. 2017 Sep;40(9):520-522. doi: 10.1016/j.tins.2017.06.010. Epub 2017 Jul 26. No abstract available.

17.

Enhanced astrocytic d-serine underlies synaptic damage after traumatic brain injury.

Perez EJ, Tapanes SA, Loris ZB, Balu DT, Sick TJ, Coyle JT, Liebl DJ.

J Clin Invest. 2017 Aug 1;127(8):3114-3125. doi: 10.1172/JCI92300. Epub 2017 Jul 17.

18.

Schizophrenia: Basic and Clinical.

Coyle JT.

Adv Neurobiol. 2017;15:255-280. doi: 10.1007/978-3-319-57193-5_9. Review.

PMID:
28674984
19.

Modeling schizophrenia pathogenesis using patient-derived induced pluripotent stem cells (iPSCs).

Noh H, Shao Z, Coyle JT, Chung S.

Biochim Biophys Acta Mol Basis Dis. 2017 Sep;1863(9):2382-2387. doi: 10.1016/j.bbadis.2017.06.019. Epub 2017 Jun 28. Review.

20.

Cortical Pyramidal Neurons Show a Selective Loss of New Synapses in Chronic Schizophrenia.

Coyle JT.

Am J Psychiatry. 2017 Jun 1;174(6):510-511. doi: 10.1176/appi.ajp.2017.17030318. No abstract available.

PMID:
28565949
21.

Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis.

Tobe BTD, Crain AM, Winquist AM, Calabrese B, Makihara H, Zhao WN, Lalonde J, Nakamura H, Konopaske G, Sidor M, Pernia CD, Yamashita N, Wada M, Inoue Y, Nakamura F, Sheridan SD, Logan RW, Brandel M, Wu D, Hunsberger J, Dorsett L, Duerr C, Basa RCB, McCarthy MJ, Udeshi ND, Mertins P, Carr SA, Rouleau GA, Mastrangelo L, Li J, Gutierrez GJ, Brill LM, Venizelos N, Chen G, Nye JS, Manji H, Price JH, McClung CA, Akiskal HS, Alda M, Chuang DM, Coyle JT, Liu Y, Teng YD, Ohshima T, Mikoshiba K, Sidman RL, Halpain S, Haggarty SJ, Goshima Y, Snyder EY.

Proc Natl Acad Sci U S A. 2017 May 30;114(22):E4462-E4471. doi: 10.1073/pnas.1700111114. Epub 2017 May 12.

22.

The Rise and Fall of the d-Serine-Mediated Gliotransmission Hypothesis.

Wolosker H, Balu DT, Coyle JT.

Trends Neurosci. 2016 Nov;39(11):712-721. doi: 10.1016/j.tins.2016.09.007. Epub 2016 Oct 11. Review.

23.

Endogenous co-agonists of the NMDA receptor modulate contextual fear in trace conditioning.

Basu AC, Puhl MD, Coyle JT.

Neurobiol Learn Mem. 2016 Dec;136:244-250. doi: 10.1016/j.nlm.2016.09.006. Epub 2016 Sep 12.

PMID:
27633914
24.

EphB3 signaling propagates synaptic dysfunction in the traumatic injured brain.

Perez EJ, Cepero ML, Perez SU, Coyle JT, Sick TJ, Liebl DJ.

Neurobiol Dis. 2016 Oct;94:73-84. doi: 10.1016/j.nbd.2016.06.007. Epub 2016 Jun 16.

25.

Glutamatergic Dysfunction in Schizophrenia Evaluated With Magnetic Resonance Spectroscopy.

Coyle JT, Konopaske G.

JAMA Psychiatry. 2016 Jul 1;73(7):649-50. doi: 10.1001/jamapsychiatry.2016.0575. No abstract available.

PMID:
27305626
26.

My Life in Clinical Neuroscience: The Beginning.

Coyle JT.

Adv Pharmacol. 2016;76:1-12. doi: 10.1016/bs.apha.2016.02.002. Epub 2016 Mar 24.

PMID:
27288071
27.

History of the Concept of Disconnectivity in Schizophrenia.

Coyle JT, Balu DT, Puhl MD, Konopaske GT.

Harv Rev Psychiatry. 2016 Mar-Apr;24(2):80-6. doi: 10.1097/HRP.0000000000000102. Review.

28.

Touchscreen assays of learning, response inhibition, and motivation in the marmoset (Callithrix jacchus).

Kangas BD, Bergman J, Coyle JT.

Anim Cogn. 2016 May;19(3):673-7. doi: 10.1007/s10071-016-0959-4. Epub 2016 Feb 3.

29.

An mGlu5-Positive Allosteric Modulator Rescues the Neuroplasticity Deficits in a Genetic Model of NMDA Receptor Hypofunction in Schizophrenia.

Balu DT, Li Y, Takagi S, Presti KT, Ramikie TS, Rook JM, Jones CK, Lindsley CW, Conn PJ, Bolshakov VY, Coyle JT.

Neuropsychopharmacology. 2016 Jul;41(8):2052-61. doi: 10.1038/npp.2016.2. Epub 2016 Jan 7.

30.

[JSNP Excellent Presentation Award for CINP2014].

Ishiwata S, Balu DT, Umino A, Coyle JT, Nishikawa T.

Nihon Shinkei Seishin Yakurigaku Zasshi. 2015 Apr;35(2):53-4. Japanese. No abstract available.

PMID:
26027070
31.

Possible compensatory mechanisms for glutamatergic disconnection found in the auditory cortex in schizophrenia.

Konopaske GT, Coyle JT.

Biol Psychiatry. 2015 Jun 1;77(11):923-4. doi: 10.1016/j.biopsych.2015.03.031. No abstract available.

32.
33.

Neuronal serine racemase regulates extracellular D-serine levels in the adult mouse hippocampus.

Ishiwata S, Umino A, Balu DT, Coyle JT, Nishikawa T.

J Neural Transm (Vienna). 2015 Aug;122(8):1099-103. doi: 10.1007/s00702-015-1388-2. Epub 2015 Mar 18.

34.

Altered prefrontal cortical MARCKS and PPP1R9A mRNA expression in schizophrenia and bipolar disorder.

Konopaske GT, Subburaju S, Coyle JT, Benes FM.

Schizophr Res. 2015 May;164(1-3):100-8. doi: 10.1016/j.schres.2015.02.005. Epub 2015 Mar 7.

35.

Subchronic pharmacological and chronic genetic NMDA receptor hypofunction differentially regulate the Akt signaling pathway and Arc expression in juvenile and adult mice.

Takagi S, Balu DT, Coyle JT.

Schizophr Res. 2015 Mar;162(1-3):216-21. doi: 10.1016/j.schres.2014.12.034. Epub 2015 Jan 12.

36.

The NMDA receptor 'glycine modulatory site' in schizophrenia: D-serine, glycine, and beyond.

Balu DT, Coyle JT.

Curr Opin Pharmacol. 2015 Feb;20:109-15. doi: 10.1016/j.coph.2014.12.004. Epub 2014 Dec 23. Review.

37.

In vivo magnetic resonance studies reveal neuroanatomical and neurochemical abnormalities in the serine racemase knockout mouse model of schizophrenia.

Puhl MD, Mintzopoulos D, Jensen JE, Gillis TE, Konopaske GT, Kaufman MJ, Coyle JT.

Neurobiol Dis. 2015 Jan;73:269-74. doi: 10.1016/j.nbd.2014.10.009. Epub 2014 Oct 23.

38.

Global biochemical profiling identifies β-hydroxypyruvate as a potential mediator of type 2 diabetes in mice and humans.

Zhang S, Wang S, Puhl MD, Jiang X, Hyrc KL, Laciny E, Wallendorf MJ, Pappan KL, Coyle JT, Wice BM.

Diabetes. 2015 Apr;64(4):1383-94. doi: 10.2337/db14-1188. Epub 2014 Nov 3.

39.

Prefrontal cortical dendritic spine pathology in schizophrenia and bipolar disorder.

Konopaske GT, Lange N, Coyle JT, Benes FM.

JAMA Psychiatry. 2014 Dec 1;71(12):1323-31. doi: 10.1001/jamapsychiatry.2014.1582.

40.

Chronic D-serine reverses arc expression and partially rescues dendritic abnormalities in a mouse model of NMDA receptor hypofunction.

Balu DT, Coyle JT.

Neurochem Int. 2014 Sep;75:76-8. doi: 10.1016/j.neuint.2014.05.015. Epub 2014 Jun 7.

41.

D-serine and serine racemase are localized to neurons in the adult mouse and human forebrain.

Balu DT, Takagi S, Puhl MD, Benneyworth MA, Coyle JT.

Cell Mol Neurobiol. 2014 Apr;34(3):419-35. doi: 10.1007/s10571-014-0027-z. Epub 2014 Jan 17.

42.

D-serine deficiency attenuates the behavioral and cellular effects induced by the hallucinogenic 5-HT(2A) receptor agonist DOI.

Santini MA, Balu DT, Puhl MD, Hill-Smith TE, Berg AR, Lucki I, Mikkelsen JD, Coyle JT.

Behav Brain Res. 2014 Feb 1;259:242-6. doi: 10.1016/j.bbr.2013.11.022. Epub 2013 Nov 20.

43.

Relapse in alcohol use disorder--reply.

Coyle JT, Ongur D.

JAMA Psychiatry. 2013 Nov;70(11):1248. doi: 10.1001/jamapsychiatry.2013.2879. No abstract available.

PMID:
24196497
44.

Brain structural alterations induced by fetal exposure to cocaine persist into adolescence and affect behavior.

Coyle JT.

JAMA Psychiatry. 2013 Oct;70(10):1113-4. doi: 10.1001/jamapsychiatry.2013.1949. No abstract available.

PMID:
23986322
45.

Changing to JAMA Psychiatry.

Coyle JT.

Arch Gen Psychiatry. 2012 Jul 1;69(7):661. doi: 10.1001/archgenpsychiatry.2012.785. No abstract available.

PMID:
23754033
46.

The JAMA Network Journals: New Names for the Archives Journals.

Bauchner H, Albert DM, Coyle JT, Freischlag JA, Larrabee WF, Levine PA, Redberg RF, Rivara FP, Robinson JK, Rosenberg RN.

Arch Gen Psychiatry. 2012 Jul 1;69(7):660. doi: 10.1001/archgenpsychiatry.2012.783. No abstract available.

PMID:
23754012
47.

The JAMA Network Journals: New Names for the Archives Journals.

Bauchner H, Albert DM, Coyle JT, Freischlag JA, Larrabee WF, Levine PA, Redberg RF, Rivara FP, Robinson JK, Rosenberg RN.

Arch Otolaryngol Head Neck Surg. 2012 Jul 1;138(7):620. doi: 10.1001/archoto.2012.1235. No abstract available.

PMID:
23753751
48.

Multiple risk pathways for schizophrenia converge in serine racemase knockout mice, a mouse model of NMDA receptor hypofunction.

Balu DT, Li Y, Puhl MD, Benneyworth MA, Basu AC, Takagi S, Bolshakov VY, Coyle JT.

Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):E2400-9. doi: 10.1073/pnas.1304308110. Epub 2013 May 31.

49.

Nitric oxide and symptom reduction in schizophrenia.

Coyle JT.

JAMA Psychiatry. 2013 Jul;70(7):664-5. doi: 10.1001/jamapsychiatry.2013.210. No abstract available.

PMID:
23699799
50.

Time-dependent effects of haloperidol on glutamine and GABA homeostasis and astrocyte activity in the rat brain.

Konopaske GT, Bolo NR, Basu AC, Renshaw PF, Coyle JT.

Psychopharmacology (Berl). 2013 Nov;230(1):57-67. doi: 10.1007/s00213-013-3136-3. Epub 2013 May 10.

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