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Items: 15


Global karst springs hydrograph dataset for research and management of the world's fastest-flowing groundwater.

Olarinoye T, Gleeson T, Marx V, Seeger S, Adinehvand R, Allocca V, Andreo B, Apaéstegui J, Apolit C, Arfib B, Auler A, Barberá JA, Batiot-Guilhe C, Bechtel T, Binet S, Bittner D, Blatnik M, Bolger T, Brunet P, Charlier JB, Chen Z, Chiogna G, Coxon G, De Vita P, Doummar J, Epting J, Fournier M, Goldscheider N, Gunn J, Guo F, Guyot JL, Howden N, Huggenberger P, Hunt B, Jeannin PY, Jiang G, Jones G, Jourde H, Karmann I, Koit O, Kordilla J, Labat D, Ladouche B, Liso IS, Liu Z, Massei N, Mazzilli N, Mudarra M, Parise M, Pu J, Ravbar N, Sanchez LH, Santo A, Sauter M, Sivelle V, Skoglund RØ, Stevanovic Z, Wood C, Worthington S, Hartmann A.

Sci Data. 2020 Feb 20;7(1):59. doi: 10.1038/s41597-019-0346-5.


Resistance to Thiacetazone Derivatives Active against Mycobacterium abscessus Involves Mutations in the MmpL5 Transcriptional Repressor MAB_4384.

Halloum I, Viljoen A, Khanna V, Craig D, Bouchier C, Brosch R, Coxon G, Kremer L.

Antimicrob Agents Chemother. 2017 Mar 24;61(4). pii: e02509-16. doi: 10.1128/AAC.02509-16. Print 2017 Apr.


A novel framework for discharge uncertainty quantification applied to 500 UK gauging stations.

Coxon G, Freer J, Westerberg IK, Wagener T, Woods R, Smith PJ.

Water Resour Res. 2015 Jul;51(7):5531-5546. Epub 2015 Jul 19.


Characterisation of triterpenes and new phenolic lipids in Cameroonian propolis.

Kardar MN, Zhang T, Coxon GD, Watson DG, Fearnley J, Seidel V.

Phytochemistry. 2014 Oct;106:156-163. doi: 10.1016/j.phytochem.2014.07.016. Epub 2014 Aug 4.


Synthesis, antitubercular activity and mechanism of resistance of highly effective thiacetazone analogues.

Coxon GD, Craig D, Corrales RM, Vialla E, Gannoun-Zaki L, Kremer L.

PLoS One. 2013;8(1):e53162. doi: 10.1371/journal.pone.0053162. Epub 2013 Jan 3.


Strategies and challenges involved in the discovery of new chemical entities during early-stage tuberculosis drug discovery.

Coxon GD, Cooper CB, Gillespie SH, McHugh TD.

J Infect Dis. 2012 May 15;205 Suppl 2:S258-64. doi: 10.1093/infdis/jis191. Epub 2012 Mar 22.


Current status and research strategies in tuberculosis drug development.

Dover LG, Coxon GD.

J Med Chem. 2011 Sep 22;54(18):6157-65. doi: 10.1021/jm200305q. Epub 2011 Aug 16. Review. No abstract available. Erratum in: J Med Chem. 2011 Dec 8;54(23):8233.


Identification of 2-aminothiazole-4-carboxylate derivatives active against Mycobacterium tuberculosis H37Rv and the beta-ketoacyl-ACP synthase mtFabH.

Al-Balas Q, Anthony NG, Al-Jaidi B, Alnimr A, Abbott G, Brown AK, Taylor RC, Besra GS, McHugh TD, Gillespie SH, Johnston BF, Mackay SP, Coxon GD.

PLoS One. 2009;4(5):e5617. doi: 10.1371/journal.pone.0005617. Epub 2009 May 19.


Benzylguanidines and other galegine analogues inducing weight loss in mice.

Coxon GD, Furman BL, Harvey AL, McTavish J, Mooney MH, Arastoo M, Kennedy AR, Tettey JM, Waigh RD.

J Med Chem. 2009 Jun 11;52(11):3457-63. doi: 10.1021/jm8011933.


Mechanisms underlying the metabolic actions of galegine that contribute to weight loss in mice.

Mooney MH, Fogarty S, Stevenson C, Gallagher AM, Palit P, Hawley SA, Hardie DG, Coxon GD, Waigh RD, Tate RJ, Harvey AL, Furman BL.

Br J Pharmacol. 2008 Apr;153(8):1669-77. doi: 10.1038/bjp.2008.37. Epub 2008 Feb 25.


Thiacetazone, an antitubercular drug that inhibits cyclopropanation of cell wall mycolic acids in mycobacteria.

Alahari A, Trivelli X, Guérardel Y, Dover LG, Besra GS, Sacchettini JC, Reynolds RC, Coxon GD, Kremer L.

PLoS One. 2007 Dec 19;2(12):e1343.


Identification of the benzodiazepines as a new class of antileishmanial agent.

Clark RL, Carter KC, Mullen AB, Coxon GD, Owusu-Dapaah G, McFarlane E, Duong Thi MD, Grant MH, Tettey JN, Mackay SP.

Bioorg Med Chem Lett. 2007 Feb 1;17(3):624-7. Epub 2006 Nov 6.


Symmetrical and unsymmetrical analogues of isoxyl; active agents against Mycobacterium tuberculosis.

Bhowruth V, Brown AK, Reynolds RC, Coxon GD, Mackay SP, Minnikin DE, Besra GS.

Bioorg Med Chem Lett. 2006 Sep 15;16(18):4743-7. Epub 2006 Jul 27.


Synthesis and properties of methyl 5-(1'R,2'S)-(2-octadecylcycloprop-1-yl)pentanoate and other omega-19 chiral cyclopropane fatty acids and esters related to mycobacterial mycolic acids.

Coxon GD, Al Dulayymi JR, Morehouse C, Brennan PJ, Besra GS, Baird MS, Minnikin DE.

Chem Phys Lipids. 2004 Jan;127(1):35-46.


Facile synthesis of (Z)-tetracos-5-enoic acid and racemic cis-4-(2-octadecylcyclopropane-1-yl)-butanoic acid.

Coxon GD, Douglas JD, Minnikin DE.

Chem Phys Lipids. 2003 Nov;126(1):49-53.


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