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Items: 1 to 50 of 223

1.

No evidence of antigenic seniority in hemagglutinin specific antibody responses after adjuvanted pandemic 2009 influenza vaccination.

Madsen A, Azimi L, Tete S, Zhou F, Krammer F, Cox RJ, Jul-Larsen Å.

Vaccine X. 2019 Jun 20;2:100029. doi: 10.1016/j.jvacx.2019.100029. eCollection 2019 Aug 9.

2.

Functional Immune Response to Influenza H1N1 in Children and Adults after Live Attenuated Influenza Virus Vaccination.

Islam S, Zhou F, Lartey S, Mohn KG, Krammer F, Cox RJ, Brokstad KA.

Scand J Immunol. 2019 Jul 3:e12801. doi: 10.1111/sji.12801. [Epub ahead of print]

PMID:
31269273
3.

Live attenuated influenza vaccine induces tonsillar follicular T helper cell responses that correlate with antibody induction.

Lartey S, Zhou F, Brokstad KA, Mohn KG, Slettevoll SA, Pathirana RD, Cox RJ.

J Infect Dis. 2019 Jun 27. pii: jiz321. doi: 10.1093/infdis/jiz321. [Epub ahead of print]

PMID:
31250024
4.

Plasma Protein Binding as an Optimizable Parameter for Acidic Drugs.

Gardiner P, Cox RJ, Grime K.

Drug Metab Dispos. 2019 Aug;47(8):865-873. doi: 10.1124/dmd.119.087163. Epub 2019 May 21.

PMID:
31113795
5.

Targeted Gene Inactivations Expose Silent Cytochalasans in Magnaporthe grisea NI980.

Wang C, Hantke V, Cox RJ, Skellam E.

Org Lett. 2019 Jun 7;21(11):4163-4167. doi: 10.1021/acs.orglett.9b01344. Epub 2019 May 17.

PMID:
31099577
6.

Research with Agricultural Animals and Wildlife.

Cox RJ, Nol P, Ellis CK, Palmer MV.

ILAR J. 2019 May 16. pii: ilz006. doi: 10.1093/ilar/ilz006. [Epub ahead of print]

PMID:
31095682
7.

Evolutionary relics dominate the small number of secondary metabolism genes in the hemibiotrophic fungus Dothistroma septosporum.

Ozturk IK, Dupont PY, Chettri P, McDougal R, Böhl OJ, Cox RJ, Bradshaw RE.

Fungal Biol. 2019 May;123(5):397-407. doi: 10.1016/j.funbio.2019.02.006. Epub 2019 Feb 27.

PMID:
31053329
8.

Structure revision of cryptosporioptides and determination of the genetic basis for dimeric xanthone biosynthesis in fungi.

Greco C, de Mattos-Shipley K, Bailey AM, Mulholland NP, Vincent JL, Willis CL, Cox RJ, Simpson TJ.

Chem Sci. 2019 Jan 21;10(10):2930-2939. doi: 10.1039/c8sc05126g. eCollection 2019 Mar 14.

9.

Low Temperature and Low UV Indexes Correlated with Peaks of Influenza Virus Activity in Northern Europe during 2010⁻2018.

Ianevski A, Zusinaite E, Shtaida N, Kallio-Kokko H, Valkonen M, Kantele A, Telling K, Lutsar I, Letjuka P, Metelitsa N, Oksenych V, Dumpis U, Vitkauskiene A, Stašaitis K, Öhrmalm C, Bondeson K, Bergqvist A, Cox RJ, Tenson T, Merits A, Kainov DE.

Viruses. 2019 Mar 1;11(3). pii: E207. doi: 10.3390/v11030207.

10.

Oxidative steps during the biosynthesis of squalestatin S1.

Lebe KE, Cox RJ.

Chem Sci. 2018 Nov 15;10(4):1227-1231. doi: 10.1039/c8sc02615g. eCollection 2019 Jan 28.

11.

Characterisation of the biosynthetic pathway to agnestins A and B reveals the reductive route to chrysophanol in fungi.

Szwalbe AJ, Williams K, Song Z, de Mattos-Shipley K, Vincent JL, Bailey AM, Willis CL, Cox RJ, Simpson TJ.

Chem Sci. 2018 Nov 26;10(1):233-238. doi: 10.1039/c8sc03778g. eCollection 2019 Jan 7.

12.

Assignment of a dubious gene cluster to melanin biosynthesis in the tomato fungal pathogen Cladosporium fulvum.

Griffiths SA, Cox RJ, Overdijk EJR, Mesarich CH, Saccomanno B, Lazarus CM, de Wit PJGM, Collemare J.

PLoS One. 2018 Dec 31;13(12):e0209600. doi: 10.1371/journal.pone.0209600. eCollection 2018.

13.

Antibody levels in a cohort of pregnant women after the 2009 influenza A(H1N1) pandemic: Waning and association with self-reported severity and duration of illness.

Tunheim G, Laake I, Robertson AH, Waalen K, Hungnes O, Naess LM, Cox RJ, Mjaaland S, Trogstad L.

Influenza Other Respir Viruses. 2019 Mar;13(2):191-200. doi: 10.1111/irv.12623. Epub 2019 Jan 1.

14.

Process Design and Optimization in the Pharmaceutical Industry: A Suzuki-Miyaura Procedure for the Synthesis of Savolitinib.

Adlington NK, Agnew LR, Campbell AD, Cox RJ, Dobson A, Barrat CF, Gall MAY, Hicks W, Howell GP, Jawor-Baczynska A, Miller-Potucka L, Pilling M, Shepherd K, Tassone R, Taylor BA, Williams A.

J Org Chem. 2019 Apr 19;84(8):4735-4747. doi: 10.1021/acs.joc.8b02351. Epub 2018 Oct 30.

PMID:
30352146
15.

Strobilurin biosynthesis in Basidiomycete fungi.

Nofiani R, de Mattos-Shipley K, Lebe KE, Han LC, Iqbal Z, Bailey AM, Willis CL, Simpson TJ, Cox RJ.

Nat Commun. 2018 Sep 26;9(1):3940. doi: 10.1038/s41467-018-06202-4.

16.

Erratum: Publisher Correction: Augmented CD4+ T-cell and humoral responses after repeated annual influenza vaccination with the same vaccine component A/H1N1pdm09 over 5 years.

Trieu MC, Zhou F, Lartey SL, Sridhar S, Mjaaland S, Cox RJ.

NPJ Vaccines. 2018 Sep 11;3:45. doi: 10.1038/s41541-018-0081-5. eCollection 2018.

17.

Augmented CD4+ T-cell and humoral responses after repeated annual influenza vaccination with the same vaccine component A/H1N1pdm09 over 5 years.

Trieu MC, Zhou F, Lartey SL, Sridhar S, Mjaaland S, Cox RJ.

NPJ Vaccines. 2018 Aug 14;3:37. doi: 10.1038/s41541-018-0069-1. eCollection 2018. Erratum in: NPJ Vaccines. 2018 Sep 11;3:45.

18.

Oryzines A & B, Maleidride Congeners from Aspergillus oryzae and Their Putative Biosynthesis.

Wasil Z, Kuhnert E, Simpson TJ, Cox RJ.

J Fungi (Basel). 2018 Aug 13;4(3). pii: E96. doi: 10.3390/jof4030096.

19.

Enfumafungin synthase represents a novel lineage of fungal triterpene cyclases.

Kuhnert E, Li Y, Lan N, Yue Q, Chen L, Cox RJ, An Z, Yokoyama K, Bills GF.

Environ Microbiol. 2018 Sep;20(9):3325-3342. doi: 10.1111/1462-2920.14333. Epub 2018 Sep 13.

20.

Investigations into the biosynthesis of the antifungal strobilurins.

Iqbal Z, Han LC, Soares-Sello AM, Nofiani R, Thormann G, Zeeck A, Cox RJ, Willis CL, Simpson TJ.

Org Biomol Chem. 2018 Aug 1;16(30):5524-5532. doi: 10.1039/c8ob00608c.

21.

Impact of erythrocyte species on assays for influenza serology.

Trombetta CM, Ulivieri C, Cox RJ, Remarque EJ, Centi C, Perini D, Piccini G, Rossi S, Marchi S, Montomoli E.

J Prev Med Hyg. 2018 Mar 30;59(1):E1-E7. doi: 10.15167/2421-4248/jpmh2018.59.1.870. eCollection 2018 Mar.

22.

Antibody Responses to Influenza A/H1N1pdm09 Virus After Pandemic and Seasonal Influenza Vaccination in Healthcare Workers: A 5-Year Follow-up Study.

Trieu MC, Jul-Larsen Å, Sævik M, Madsen A, Nøstbakken JK, Zhou F, Skrede S, Cox RJ.

Clin Infect Dis. 2019 Jan 18;68(3):382-392. doi: 10.1093/cid/ciy487.

23.

T follicular-like helper cells in the peripheral blood of patients with primary Sjögren's syndrome.

Brokstad KA, Fredriksen M, Zhou F, Bergum B, Brun JG, Cox RJ, Skarstein K.

Scand J Immunol. 2018 Jun 8:e12679. doi: 10.1111/sji.12679. [Epub ahead of print]

24.

Discovery of Highly Isoform Selective Orally Bioavailable Phosphoinositide 3-Kinase (PI3K)-γ Inhibitors.

Pemberton N, Mogemark M, Arlbrandt S, Bold P, Cox RJ, Gardelli C, Holden NS, Karabelas K, Karlsson J, Lever S, Li X, Lindmark H, Norberg M, Perry MWD, Petersen J, Rodrigo Blomqvist S, Thomas M, Tyrchan C, Westin Eriksson A, Zlatoidsky P, Öster L.

J Med Chem. 2018 Jun 28;61(12):5435-5441. doi: 10.1021/acs.jmedchem.8b00447. Epub 2018 Jun 18.

PMID:
29852070
25.

The cycloaspeptides: uncovering a new model for methylated nonribosomal peptide biosynthesis.

de Mattos-Shipley KMJ, Greco C, Heard DM, Hough G, Mulholland NP, Vincent JL, Micklefield J, Simpson TJ, Willis CL, Cox RJ, Bailey AM.

Chem Sci. 2018 Apr 10;9(17):4109-4117. doi: 10.1039/c8sc00717a. eCollection 2018 May 7.

26.

Three previously unrecognised classes of biosynthetic enzymes revealed during the production of xenovulene A.

Schor R, Schotte C, Wibberg D, Kalinowski J, Cox RJ.

Nat Commun. 2018 May 17;9(1):1963. doi: 10.1038/s41467-018-04364-9.

27.

Improving influenza vaccines: challenges to effective implementation.

Zhou F, Trieu MC, Davies R, Cox RJ.

Curr Opin Immunol. 2018 Aug;53:88-95. doi: 10.1016/j.coi.2018.04.010. Epub 2018 Apr 30. Review.

PMID:
29719276
28.

Novel activities of safe-in-human broad-spectrum antiviral agents.

Ianevski A, Zusinaite E, Kuivanen S, Strand M, Lysvand H, Teppor M, Kakkola L, Paavilainen H, Laajala M, Kallio-Kokko H, Valkonen M, Kantele A, Telling K, Lutsar I, Letjuka P, Metelitsa N, Oksenych V, Bjørås M, Nordbø SA, Dumpis U, Vitkauskiene A, Öhrmalm C, Bondeson K, Bergqvist A, Aittokallio T, Cox RJ, Evander M, Hukkanen V, Marjomaki V, Julkunen I, Vapalahti O, Tenson T, Merits A, Kainov D.

Antiviral Res. 2018 Jun;154:174-182. doi: 10.1016/j.antiviral.2018.04.016. Epub 2018 Apr 23. Review.

PMID:
29698664
29.

Impact of pre-existing immunity on the induction of functional cross-reactive anti-hemagglutinin stalk antibodies following vaccination with an AS03 adjuvanted pandemic H1N1 vaccine.

Tete SM, Jul-Larsen Å, Rostami S, Lunde THF, Søland H, Krammer F, Cox RJ.

Vaccine. 2018 Apr 12;36(16):2213-2219. doi: 10.1016/j.vaccine.2018.02.022. Epub 2018 Mar 13.

PMID:
29548607
30.

Recent advances in reconstructing microbial secondary metabolites biosynthesis in Aspergillus spp.

He Y, Wang B, Chen W, Cox RJ, He J, Chen F.

Biotechnol Adv. 2018 May - Jun;36(3):739-783. doi: 10.1016/j.biotechadv.2018.02.001. Epub 2018 Feb 5. Review.

PMID:
29421302
31.

Antibody response to seasonal influenza vaccination in patients with multiple sclerosis receiving immunomodulatory therapy.

Olberg HK, Eide GE, Cox RJ, Jul-Larsen Å, Lartey SL, Vedeler CA, Myhr KM.

Eur J Neurol. 2018 Mar;25(3):527-534. doi: 10.1111/ene.13537. Epub 2018 Jan 6.

PMID:
29205701
32.

Mucosal Administration of Cycle-Di-Nucleotide-Adjuvanted Virosomes Efficiently Induces Protection against Influenza H5N1 in Mice.

Ebensen T, Debarry J, Pedersen GK, Blazejewska P, Weissmann S, Schulze K, McCullough KC, Cox RJ, Guzmán CA.

Front Immunol. 2017 Sep 28;8:1223. doi: 10.3389/fimmu.2017.01223. eCollection 2017.

33.

Orange, red, yellow: biosynthesis of azaphilone pigments in Monascus fungi.

Chen W, Chen R, Liu Q, He Y, He K, Ding X, Kang L, Guo X, Xie N, Zhou Y, Lu Y, Cox RJ, Molnár I, Li M, Shao Y, Chen F.

Chem Sci. 2017 Jul 1;8(7):4917-4925. doi: 10.1039/c7sc00475c. Epub 2017 Apr 24.

34.

Immune responses after live attenuated influenza vaccination.

Mohn KG, Smith I, Sjursen H, Cox RJ.

Hum Vaccin Immunother. 2018 Mar 4;14(3):571-578. doi: 10.1080/21645515.2017.1377376. Epub 2018 Jan 3. Review.

35.

Influenza Virus Hemagglutinin Stalk-Specific Antibodies in Human Serum are a Surrogate Marker for In Vivo Protection in a Serum Transfer Mouse Challenge Model.

Jacobsen H, Rajendran M, Choi A, Sjursen H, Brokstad KA, Cox RJ, Palese P, Krammer F, Nachbagauer R.

MBio. 2017 Sep 19;8(5). pii: e01463-17. doi: 10.1128/mBio.01463-17.

36.

Influenza A haemagglutinin specific IgG responses in children and adults after seasonal trivalent live attenuated influenza vaccination.

Islam S, Mohn KG, Krammer F, Sanne M, Bredholt G, Jul-Larsen Å, Tete SM, Zhou F, Brokstad KA, Cox RJ.

Vaccine. 2017 Oct 9;35(42):5666-5673. doi: 10.1016/j.vaccine.2017.08.044. Epub 2017 Sep 9.

PMID:
28899626
37.

Using White-tailed Deer (Odocoileus virginianus) in Infectious Disease Research.

Palmer MV, Cox RJ, Waters WR, Thacker TC, Whipple DL.

J Am Assoc Lab Anim Sci. 2017 Jul 1;56(4):350-360.

38.

Genetic and chemical characterisation of the cornexistin pathway provides further insight into maleidride biosynthesis.

Williams K, Szwalbe AJ, Dickson C, Desson TR, Mulholland NP, Vincent JL, Clough JM, Bailey AM, Butts CP, Willis CL, Simpson TJ, Cox RJ.

Chem Commun (Camb). 2017 Jul 11;53(56):7965-7968. doi: 10.1039/c7cc03303f.

PMID:
28660939
39.

High Prevalence of Humoral and Cellular Immunity to Influenza Viruses in Preschool Children Living in Addis Ababa, Ethiopia.

Dembinski JL, Mihret A, Yimer SA, Tessema B, Trieu MC, Tarekegn A, Getachew N, Cox RJ, Oftung F, Haneberg B, Aseffa A, Mjaaland S.

Open Forum Infect Dis. 2017 Feb 11;4(1):ofx026. doi: 10.1093/ofid/ofx026. eCollection 2017 Winter.

40.

Structural Revision and Biosynthesis of the Fungal Phytotoxins Phyllostictines A and B.

Trenti F, Cox RJ.

J Nat Prod. 2017 May 26;80(5):1235-1240. doi: 10.1021/acs.jnatprod.7b00183. Epub 2017 May 3.

PMID:
28467083
41.

Substrate selectivity of an isolated enoyl reductase catalytic domain from an iterative highly reducing fungal polyketide synthase reveals key components of programming.

Roberts DM, Bartel C, Scott A, Ivison D, Simpson TJ, Cox RJ.

Chem Sci. 2017 Feb 1;8(2):1116-1126. doi: 10.1039/c6sc03496a. Epub 2016 Sep 26.

42.

No evidence of a role of the β4 subunit of the nicotinic acetylcholine receptor in alcohol-related behaviors.

Kamens HM, Silva C, McCarthy R, Cox RJ, Ehringer MA.

BMC Res Notes. 2017 Apr 5;10(1):151. doi: 10.1186/s13104-017-2470-7.

43.

Boosting of Cross-Reactive and Protection-Associated T Cells in Children After Live Attenuated Influenza Vaccination.

Mohn KGI, Zhou F, Brokstad KA, Sridhar S, Cox RJ.

J Infect Dis. 2017 May 15;215(10):1527-1535. doi: 10.1093/infdis/jix165.

44.

Selected Mutations Reveal New Intermediates in the Biosynthesis of Mupirocin and the Thiomarinol Antibiotics.

Gao SS, Wang L, Song Z, Hothersall J, Stevens ER, Connolly J, Winn PJ, Cox RJ, Crump MP, Race PR, Thomas CM, Simpson TJ, Willis CL.

Angew Chem Int Ed Engl. 2017 Mar 27;56(14):3930-3934. doi: 10.1002/anie.201611590. Epub 2017 Feb 9.

PMID:
28181382
45.

In vitro kinetic study of the squalestatin tetraketide synthase dehydratase reveals the stereochemical course of a fungal highly reducing polyketide synthase.

Liddle E, Scott A, Han LC, Ivison D, Simpson TJ, Willis CL, Cox RJ.

Chem Commun (Camb). 2017 Feb 4;53(10):1727-1730. doi: 10.1039/c6cc10172k. Epub 2017 Jan 20.

PMID:
28106181
46.

Long-term Maintenance of the Influenza-Specific Cross-Reactive Memory CD4+ T-Cell Responses Following Repeated Annual Influenza Vaccination.

Trieu MC, Zhou F, Lartey S, Jul-Larsen Å, Mjaaland S, Sridhar S, Cox RJ.

J Infect Dis. 2017 Mar 1;215(5):740-749. doi: 10.1093/infdis/jiw619.

PMID:
28007925
47.

Comparative analysis of influenza A(H3N2) virus hemagglutinin specific IgG subclass and IgA responses in children and adults after influenza vaccination.

Manenti A, Tete SM, Mohn KG, Jul-Larsen Å, Gianchecchi E, Montomoli E, Brokstad KA, Cox RJ.

Vaccine. 2017 Jan 3;35(1):191-198. doi: 10.1016/j.vaccine.2016.10.024. Epub 2016 Oct 24.

48.

Pulmonary changes in Norwegian fatal cases of pandemic influenza H1N1 (2009) infection: a morphologic and molecular genetic study.

Voltersvik P, Aqrawi LA, Dudman S, Hungnes O; Norwegian Lung Pathology Group, Bostad L, Brokstad KA, Cox RJ.

Influenza Other Respir Viruses. 2016 Nov;10(6):525-531. doi: 10.1111/irv.12410. Epub 2016 Sep 1.

49.
50.

Live Attenuated Influenza Vaccine in Children Induces B-Cell Responses in Tonsils.

Mohn KG, Brokstad KA, Pathirana RD, Bredholt G, Jul-Larsen Å, Trieu MC, Lartey SL, Montomoli E, Tøndel C, Aarstad HJ, Cox RJ.

J Infect Dis. 2016 Sep 1;214(5):722-31. doi: 10.1093/infdis/jiw230. Epub 2016 May 30. Erratum in: J Infect Dis. 2016 Oct 3;:.

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