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Items: 1 to 50 of 88

1.
2.

Corrigendum: Whole-genome characterization of chemoresistant ovarian cancer.

Patch AM, Christie EL, Etemadmoghadam D, Garsed DW, George J, Fereday S, Nones K, Cowin P, Alsop K, Bailey PJ, Kassahn KS, Newell F, Quinn MC, Kazakoff S, Quek K, Wilhelm-Benartzi C, Curry E, Leong HS; Australian Ovarian Cancer Study Group, Hamilton A, Mileshkin L, Au-Yeung G, Kennedy C, Hung J, Chiew YE, Harnett P, Friedlander M, Quinn M, Pyman J, Cordner S, O'Brien P, Leditschke J, Young G, Strachan K, Waring P, Azar W, Mitchell C, Traficante N, Hendley J, Thorne H, Shackleton M, Miller DK, Arnau GM, Tothill RW, Holloway TP, Semple T, Harliwong I, Nourse C, Nourbakhsh E, Manning S, Idrisoglu S, Bruxner TJ, Christ AN, Poudel B, Holmes O, Anderson M, Leonard C, Lonie A, Hall N, Wood S, Taylor DF, Xu Q, Fink JL, Waddell N, Drapkin R, Stronach E, Gabra H, Brown R, Jewell A, Nagaraj SH, Markham E, Wilson PJ, Ellul J, McNally O, Doyle MA, Vedururu R, Stewart C, Lengyel E, Pearson JV, Waddell N, deFazio A, Grimmond SM, Bowtell DD.

Nature. 2015 Nov 19;527(7578):398. doi: 10.1038/nature15716. Epub 2015 Oct 21. No abstract available.

PMID:
26503049
3.

The Patentability of Stem Cells in Australia.

Petering J, Cowin P.

Cold Spring Harb Perspect Med. 2015 Jul 1;5(10). pii: a020966. doi: 10.1101/cshperspect.a020966. Review.

4.

Whole-genome characterization of chemoresistant ovarian cancer.

Patch AM, Christie EL, Etemadmoghadam D, Garsed DW, George J, Fereday S, Nones K, Cowin P, Alsop K, Bailey PJ, Kassahn KS, Newell F, Quinn MC, Kazakoff S, Quek K, Wilhelm-Benartzi C, Curry E, Leong HS; Australian Ovarian Cancer Study Group, Hamilton A, Mileshkin L, Au-Yeung G, Kennedy C, Hung J, Chiew YE, Harnett P, Friedlander M, Quinn M, Pyman J, Cordner S, O'Brien P, Leditschke J, Young G, Strachan K, Waring P, Azar W, Mitchell C, Traficante N, Hendley J, Thorne H, Shackleton M, Miller DK, Arnau GM, Tothill RW, Holloway TP, Semple T, Harliwong I, Nourse C, Nourbakhsh E, Manning S, Idrisoglu S, Bruxner TJ, Christ AN, Poudel B, Holmes O, Anderson M, Leonard C, Lonie A, Hall N, Wood S, Taylor DF, Xu Q, Fink JL, Waddell N, Drapkin R, Stronach E, Gabra H, Brown R, Jewell A, Nagaraj SH, Markham E, Wilson PJ, Ellul J, McNally O, Doyle MA, Vedururu R, Stewart C, Lengyel E, Pearson JV, Waddell N, deFazio A, Grimmond SM, Bowtell DD.

Nature. 2015 May 28;521(7553):489-94. doi: 10.1038/nature14410. Erratum in: Nature. 2015 Nov 19;527(7578):398.

PMID:
26017449
5.

Inferring copy number and genotype in tumour exome data.

Amarasinghe KC, Li J, Hunter SM, Ryland GL, Cowin PA, Campbell IG, Halgamuge SK.

BMC Genomics. 2014 Aug 28;15:732. doi: 10.1186/1471-2164-15-732.

6.

Bringing law and order to the cytoskeleton and cell junctions: an interview with Werner Franke.

Franke W, Cowin P.

Cell Commun Adhes. 2014 Jun;21(3):103-7. doi: 10.3109/15419061.2014.914786. No abstract available.

PMID:
24854769
7.

Highlighting Kathleen Green and Mario Delmar, guest editors of special issue (part 2): junctional targets of skin and heart disease.

Cowin P.

Cell Commun Adhes. 2014 Jun;21(3):101-2. doi: 10.3109/15419061.2014.908062.

PMID:
24854768
8.

Highlights from special issue: junctional targets of skin and heart diseases.

Delmar M, Green K, Cowin P.

Cell Commun Adhes. 2014 Feb;21(1):1. doi: 10.3109/15419061.2014.876847.

PMID:
24460196
9.

Highlighting young investigators: guest editor Ramanuj DasGupta. Ram DasGupta: pushing the boundaries of β-catenin signaling and drug development.

Cowin P.

Cell Commun Adhes. 2013 Dec;20(6):151-3. doi: 10.3109/15419061.2013.858134. Epub 2013 Nov 25.

PMID:
24274117
10.

Ltbp1L is focally induced in embryonic mammary mesenchyme, demarcates the ductal luminal lineage and is upregulated during involution.

Chandramouli A, Simundza J, Pinderhughes A, Hiremath M, Droguett G, Frendewey D, Cowin P.

Breast Cancer Res. 2013 Nov 21;15(6):R111. doi: 10.1186/bcr3578.

11.

Gli activity is critical at multiple stages of embryonic mammary and nipple development.

Chandramouli A, Hatsell SJ, Pinderhughes A, Koetz L, Cowin P.

PLoS One. 2013 Nov 18;8(11):e79845. doi: 10.1371/journal.pone.0079845. eCollection 2013.

12.

Adhesion G-protein-coupled receptors: elusive hybrids come of age.

Simundza J, Cowin P.

Cell Commun Adhes. 2013 Dec;20(6):213-26. doi: 10.3109/15419061.2013.855727. Epub 2013 Nov 14. Review. Erratum in: Cell Commun Adhes. 2013 Dec;20(6):226. Cell Commun Adhes. 2014 Oct;21(5):267.

13.

Massively-parallel sequencing assists the diagnosis and guided treatment of cancers of unknown primary.

Tothill RW, Li J, Mileshkin L, Doig K, Siganakis T, Cowin P, Fellowes A, Semple T, Fox S, Byron K, Kowalczyk A, Thomas D, Schofield P, Bowtell DD.

J Pathol. 2013 Dec;231(4):413-23. doi: 10.1002/path.4251.

PMID:
24037760
14.

LRP1B deletion in high-grade serous ovarian cancers is associated with acquired chemotherapy resistance to liposomal doxorubicin.

Cowin PA, George J, Fereday S, Loehrer E, Van Loo P, Cullinane C, Etemadmoghadam D, Ftouni S, Galletta L, Anglesio MS, Hendley J, Bowes L, Sheppard KE, Christie EL, Pearson RB, Harnett PR, Heinzelmann-Schwarz V, Friedlander M, McNally O, Quinn M, Campbell P, deFazio A, Bowtell DD; Australian Ovarian Cancer Study.

Cancer Res. 2012 Aug 15;72(16):4060-73.

15.

A systematic screen for micro-RNAs regulating the canonical Wnt pathway.

Anton R, Chatterjee SS, Simundza J, Cowin P, Dasgupta R.

PLoS One. 2011;6(10):e26257. doi: 10.1371/journal.pone.0026257. Epub 2011 Oct 17.

16.

Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers.

Helland Å, Anglesio MS, George J, Cowin PA, Johnstone CN, House CM, Sheppard KE, Etemadmoghadam D, Melnyk N, Rustgi AK, Phillips WA, Johnsen H, Holm R, Kristensen GB, Birrer MJ; Australian Ovarian Cancer Study Group, Pearson RB, Børresen-Dale AL, Huntsman DG, deFazio A, Creighton CJ, Smyth GK, Bowtell DD.

PLoS One. 2011 Apr 13;6(4):e18064. doi: 10.1371/journal.pone.0018064.

17.

Choreographing metastasis to the tune of LTBP.

Chandramouli A, Simundza J, Pinderhughes A, Cowin P.

J Mammary Gland Biol Neoplasia. 2011 Jun;16(2):67-80. doi: 10.1007/s10911-011-9215-3. Epub 2011 Apr 15.

18.

IL6-STAT3-HIF signaling and therapeutic response to the angiogenesis inhibitor sunitinib in ovarian clear cell cancer.

Anglesio MS, George J, Kulbe H, Friedlander M, Rischin D, Lemech C, Power J, Coward J, Cowin PA, House CM, Chakravarty P, Gorringe KL, Campbell IG; Australian Ovarian Cancer Study Group, Okamoto A, Birrer MJ, Huntsman DG, de Fazio A, Kalloger SE, Balkwill F, Gilks CB, Bowtell DD.

Clin Cancer Res. 2011 Apr 15;17(8):2538-48. doi: 10.1158/1078-0432.CCR-10-3314. Epub 2011 Feb 22.

19.

A mouse transgenic approach to induce β-catenin signaling in a temporally controlled manner.

Mukherjee A, Soyal SM, Li J, Ying Y, Szwarc MM, He B, Kommagani R, Hodgson MC, Hiremath M, Cowin P, Lydon JP.

Transgenic Res. 2011 Aug;20(4):827-40. doi: 10.1007/s11248-010-9466-6. Epub 2010 Dec 2.

PMID:
21120693
20.

Amplicon-dependent CCNE1 expression is critical for clonogenic survival after cisplatin treatment and is correlated with 20q11 gain in ovarian cancer.

Etemadmoghadam D, George J, Cowin PA, Cullinane C, Kansara M; Australian Ovarian Cancer Study Group, Gorringe KL, Smyth GK, Bowtell DD.

PLoS One. 2010 Nov 12;5(11):e15498. doi: 10.1371/journal.pone.0015498.

21.

Key signaling nodes in mammary gland development and cancer: β-catenin.

Incassati A, Chandramouli A, Eelkema R, Cowin P.

Breast Cancer Res. 2010;12(6):213. doi: 10.1186/bcr2723. Epub 2010 Nov 3. Review.

22.

Copy number analysis identifies novel interactions between genomic loci in ovarian cancer.

Gorringe KL, George J, Anglesio MS, Ramakrishna M, Etemadmoghadam D, Cowin P, Sridhar A, Williams LH, Boyle SE, Yanaihara N, Okamoto A, Urashima M, Smyth GK, Campbell IG, Bowtell DD; Australian Ovarian Cancer Study.

PLoS One. 2010 Sep 10;5(9). pii: e11408. doi: 10.1371/journal.pone.0011408.

23.

Distinct function of androgen receptor coactivator ARA70α and ARA70β in mammary gland development, and in breast cancer.

Wu X, Chen F, Sahin A, Albarracin C, Pei Z, Zou X, Singh B, Xu R, Daniels G, Li Y, Wei J, Blake M, Schneider RJ, Cowin P, Lee P.

Breast Cancer Res Treat. 2011 Jul;128(2):391-400. doi: 10.1007/s10549-010-1131-5. Epub 2010 Sep 3.

PMID:
20814820
24.

Profiling the cancer genome.

Cowin PA, Anglesio M, Etemadmoghadam D, Bowtell DD.

Annu Rev Genomics Hum Genet. 2010;11:133-59. doi: 10.1146/annurev-genom-082509-141536. Review.

PMID:
20590430
25.

Molecular mechanisms guiding embryonic mammary gland development.

Cowin P, Wysolmerski J.

Cold Spring Harb Perspect Biol. 2010 Jun;2(6):a003251. doi: 10.1101/cshperspect.a003251. Epub 2010 May 19. Review.

26.

Vinclozolin exposure in utero induces postpubertal prostatitis and reduces sperm production via a reversible hormone-regulated mechanism.

Cowin PA, Gold E, Aleksova J, O'Bryan MK, Foster PM, Scott HS, Risbridger GP.

Endocrinology. 2010 Feb;151(2):783-92. doi: 10.1210/en.2009-0982. Epub 2010 Jan 7.

27.

Links between transforming growth factor-beta and canonical Wnt signaling yield new insights into breast cancer susceptibility, suppression and tumor heterogeneity.

Incassati A, Pinderhughes A, Eelkema R, Cowin P.

Breast Cancer Res. 2009;11(3):103. doi: 10.1186/bcr2253. Epub 2009 May 20.

28.

MMTV-Wnt1 and -DeltaN89beta-catenin induce canonical signaling in distinct progenitors and differentially activate Hedgehog signaling within mammary tumors.

Teissedre B, Pinderhughes A, Incassati A, Hatsell SJ, Hiremath M, Cowin P.

PLoS One. 2009;4(2):e4537. doi: 10.1371/journal.pone.0004537. Epub 2009 Feb 19. Erratum in: PLoS ONE. 2009;4(3). doi: 10.1371/annotation/3706d475-e082-4be6-b328-7d8aea02b986.

29.

Breast cancer progression: controversies and consensus in the molecular mechanisms of metastasis and EMT.

Cowin P, Welch DR.

J Mammary Gland Biol Neoplasia. 2007 Sep;12(2-3):99-102. doi: 10.1007/s10911-007-9041-9. No abstract available.

30.

Early-onset endocrine disruptor-induced prostatitis in the rat.

Cowin PA, Foster P, Pedersen J, Hedwards S, McPherson SJ, Risbridger GP.

Environ Health Perspect. 2008 Jul;116(7):923-9. doi: 10.1289/ehp.11239.

31.

Plakoglobin is required for effective intermediate filament anchorage to desmosomes.

Acehan D, Petzold C, Gumper I, Sabatini DD, Müller EJ, Cowin P, Stokes DL.

J Invest Dermatol. 2008 Nov;128(11):2665-75. doi: 10.1038/jid.2008.141. Epub 2008 May 22.

32.

The pattern of beta-catenin responsiveness within the mammary gland is regulated by progesterone receptor.

Hiremath M, Lydon JP, Cowin P.

Development. 2007 Oct;134(20):3703-12. Epub 2007 Sep 19.

33.

Gli3-mediated repression of Hedgehog targets is required for normal mammary development.

Hatsell SJ, Cowin P.

Development. 2006 Sep;133(18):3661-70. Epub 2006 Aug 16.

34.

Formation of human prostate tissue from embryonic stem cells.

Taylor RA, Cowin PA, Cunha GR, Pera M, Trounson AO, Pedersen J, Risbridger GP.

Nat Methods. 2006 Mar;3(3):179-81.

PMID:
16489334
35.

17beta-estradiol induces apoptosis in the developing rodent prostate independently of ERalpha or ERbeta.

Taylor RA, Cowin P, Couse JF, Korach KS, Risbridger GP.

Endocrinology. 2006 Jan;147(1):191-200. Epub 2005 Oct 13.

PMID:
16223864
36.

Cadherins and catenins in breast cancer.

Cowin P, Rowlands TM, Hatsell SJ.

Curr Opin Cell Biol. 2005 Oct;17(5):499-508. Review.

PMID:
16107313
37.

Estrogen receptor positivity in mammary tumors of Wnt-1 transgenic mice is influenced by collaborating oncogenic mutations.

Zhang X, Podsypanina K, Huang S, Mohsin SK, Chamness GC, Hatsell S, Cowin P, Schiff R, Li Y.

Oncogene. 2005 Jun 16;24(26):4220-31.

PMID:
15824740
38.

Bone morphogenetic protein signaling regulates postnatal hair follicle differentiation and cycling.

Guha U, Mecklenburg L, Cowin P, Kan L, O'Guin WM, D'Vizio D, Pestell RG, Paus R, Kessler JA.

Am J Pathol. 2004 Sep;165(3):729-40.

39.

Beta-catenin and cyclin D1: connecting development to breast cancer.

Rowlands TM, Pechenkina IV, Hatsell S, Cowin P.

Cell Cycle. 2004 Feb;3(2):145-8. Review.

PMID:
14712077
40.

Mammary gland development requires syndecan-1 to create a beta-catenin/TCF-responsive mammary epithelial subpopulation.

Liu BY, Kim YC, Leatherberry V, Cowin P, Alexander CM.

Oncogene. 2003 Dec 18;22(58):9243-53.

PMID:
14681683
41.

Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells.

Li Y, Welm B, Podsypanina K, Huang S, Chamorro M, Zhang X, Rowlands T, Egeblad M, Cowin P, Werb Z, Tan LK, Rosen JM, Varmus HE.

Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15853-8. Epub 2003 Dec 10.

42.

Beta-catenin and Tcfs in mammary development and cancer.

Hatsell S, Rowlands T, Hiremath M, Cowin P.

J Mammary Gland Biol Neoplasia. 2003 Apr;8(2):145-58. Review.

PMID:
14635791
43.

Untangling desmosomal knots with electron tomography.

He W, Cowin P, Stokes DL.

Science. 2003 Oct 3;302(5642):109-13.

44.

Dissecting the roles of beta-catenin and cyclin D1 during mammary development and neoplasia.

Rowlands TM, Pechenkina IV, Hatsell SJ, Pestell RG, Cowin P.

Proc Natl Acad Sci U S A. 2003 Sep 30;100(20):11400-5. Epub 2003 Sep 17.

45.

Plakoglobin is O-glycosylated close to the N-terminal destruction box.

Hatsell S, Medina L, Merola J, Haltiwanger R, Cowin P.

J Biol Chem. 2003 Sep 26;278(39):37745-52. Epub 2003 Jul 7.

46.

Molecular cloning of the mouse Ltbp-1 gene reveals tissue specific expression of alternatively spliced forms.

Noguera I, Obata H, Gualandris A, Cowin P, Rifkin DB.

Gene. 2003 Apr 10;308:31-41.

PMID:
12711388
47.

Secondary aerosolization of viable Bacillus anthracis spores in a contaminated US Senate Office.

Weis CP, Intrepido AJ, Miller AK, Cowin PG, Durno MA, Gebhardt JS, Bull R.

JAMA. 2002 Dec 11;288(22):2853-8.

PMID:
12472327
48.

Appearance of Langerhans cells in the epidermis of Tgfb1(-/-) SCID mice: paracrine and autocrine effects of transforming growth factor-beta 1 and -beta 2(1).

Thomas RM, Belsito DV, Huang C, Chen Lz LZ, Ormsby I, Simmons WJ, Cowin P, Shaw J, Doetschman T, Thorbecke GJ.

J Invest Dermatol. 2001 Dec;117(6):1574-80.

49.

Deconstructing desmoplakin.

Hatsell S, Cowin P.

Nat Cell Biol. 2001 Dec;3(12):E270-2. Review. No abstract available.

PMID:
11781580
50.

Delta N89 beta-catenin induces precocious development, differentiation, and neoplasia in mammary gland.

Imbert A, Eelkema R, Jordan S, Feiner H, Cowin P.

J Cell Biol. 2001 Apr 30;153(3):555-68.

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