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Impact on survival of combination inhalers in patients with COPD at high risk of cardiovascular events.

Patel HC, Hayward C, Patel KS, Claggett B, Vazir A, Cowie MR.

Int J Cardiol. 2019 Nov 26. pii: S0167-5273(19)33229-2. doi: 10.1016/j.ijcard.2019.11.138. [Epub ahead of print]


Health economic evaluation of rivaroxaban in the treatment of patients with chronic coronary artery disease or peripheral artery disease.

Cowie MR, Lamy A, Levy P, Mealing S, Millier A, Mernagh P, Cristeau O, Bowrin K, Briere JB.

Cardiovasc Res. 2019 Nov 28. pii: cvz278. doi: 10.1093/cvr/cvz278. [Epub ahead of print]


Bioprofiles and mechanistic pathways associated with Cheyne-Stokes respiration: insights from the SERVE-HF trial.

Ferreira JP, Duarte K, Woehrle H, Cowie MR, Angermann C, d'Ortho MP, Erdmann E, Levy P, Simonds AK, Somers VK, Teschler H, Wegscheider K, Bresso E, Dominique-Devignes M, Rossignol P, Koenig W, Zannad F.

Clin Res Cardiol. 2019 Nov 29. doi: 10.1007/s00392-019-01578-9. [Epub ahead of print]


Nightly sleep apnea severity in patients with atrial fibrillation: Potential applications of long-term sleep apnea monitoring.

Linz D, Baumert M, Desteghe L, Kadhim K, Vernooy K, Kalman JM, Dobrev D, Arzt M, Sastry M, Crijns HJGM, Schotten U, Cowie MR, McEvoy RD, Heidbuchel H, Hendriks J, Sanders P, Lau DH.

Int J Cardiol Heart Vasc. 2019 Oct 18;24:100424. doi: 10.1016/j.ijcha.2019.100424. eCollection 2019 Sep. Review.


Improving the quality of care for patients with or at risk of atrial fibrillation: an improvement initiative in UK general practices.

Adeleke Y, Matthew D, Porter B, Woodcock T, Yap J, Hashmy S, Mathew A, Grant R, Kaba A, Unger-Graeber B, Khan S, Bell D, Cowie MR.

Open Heart. 2019 Oct 15;6(2):e001086. doi: 10.1136/openhrt-2019-001086. eCollection 2019.


Route to heart failure diagnosis in English primary care: a retrospective cohort study of variation.

Kim D, Hayhoe B, Aylin P, Majeed A, Cowie MR, Bottle A.

Br J Gen Pract. 2019 Sep 26;69(687):e697-e705. doi: 10.3399/bjgp19X705485. Print 2019 Oct.


Letter in reference to "Defining a 'frequent admitter' phenotype among patients with repeat heart failure admissions".

Bottle A, Cowie MR.

Eur J Heart Fail. 2019 Aug 13. doi: 10.1002/ejhf.1590. [Epub ahead of print] No abstract available.


Reproducibility of in-hospital worsening heart failure event adjudication in the RELAX-AHF-EU trial.

Hallén J, Maggioni AP, Lopez-De-Sa E, Turazza FM, Witte K, Erdmann E, Dahlström U, Ertl G, Nielsen OW, Sendon JL, Holbro T, Chen CW, Gimpelewicz C, Cowie MR.

Eur J Heart Fail. 2019 Jul 29. doi: 10.1002/ejhf.1574. [Epub ahead of print] No abstract available.


Exploring digital technology's potential for cardiology.

Cowie MR.

Eur Heart J. 2019 Jul 21;40(28):2283-2284. doi: 10.1093/eurheartj/ehz490. No abstract available.


Expert consensus document: Reporting checklist for quantification of pulmonary congestion by lung ultrasound in heart failure.

Platz E, Jhund PS, Girerd N, Pivetta E, McMurray JJV, Peacock WF, Masip J, Martin-Sanchez FJ, Miró Ò, Price S, Cullen L, Maisel AS, Vrints C, Cowie MR, DiSomma S, Bueno H, Mebazaa A, Gualandro DM, Tavares M, Metra M, Coats AJS, Ruschitzka F, Seferovic PM, Mueller C; Study Group on Acute Heart Failure of the Acute Cardiovascular Care Association and the Heart Failure Association of the European Society of Cardiology.

Eur J Heart Fail. 2019 Jul;21(7):844-851. doi: 10.1002/ejhf.1499. Epub 2019 Jun 19.


Association of serious adverse events with Cheyne-Stokes respiration characteristics in patients with systolic heart failure and central sleep apnoea: A SERVE-Heart Failure substudy analysis.

Javed F, Tamisier R, Pepin JL, Cowie MR, Wegscheider K, Angermann C, d'Ortho MP, Erdmann E, Simonds AK, Somers VK, Teschler H, Levy P, Armitstead J, Woehrle H.

Respirology. 2019 Jun 20. doi: 10.1111/resp.13613. [Epub ahead of print]


Remote Management of Heart Failure: An Overview of Telemonitoring Technologies.

Brahmbhatt DH, Cowie MR.

Card Fail Rev. 2019 May 24;5(2):86-92. doi: 10.15420/cfr.2019.5.3. eCollection 2019 May. Review.


Is the digital revolution the dawn of a golden age or just the next fad?

Cowie MR.

Cardiovasc Res. 2019 Sep 1;115(11):e113-e114. doi: 10.1093/cvr/cvz115. No abstract available.


Physicians' guideline adherence is associated with long-term heart failure mortality in outpatients with heart failure with reduced ejection fraction: the QUALIFY international registry.

Komajda M, Schöpe J, Wagenpfeil S, Tavazzi L, Böhm M, Ponikowski P, Anker SD, Filippatos GS, Cowie MR; QUALIFY Investigators.

Eur J Heart Fail. 2019 Jul;21(7):921-929. doi: 10.1002/ejhf.1459. Epub 2019 Apr 1.


Effect of the Optimize Heart Failure Care Program on clinical and patient outcomes - The pilot implementation in Vietnam.

Do TNP, Do QH, Cowie MR, Ha NB, Do VD, Do TH, Nguyen TTH, Tran TL, Nguyen TNO, Nguyen TMH, Chau TTQ, Nguyen TTT, Nguyen CT, Tran KDT, Nguyen TND, Nguyen NYT, Le KT, Phan TT, Vo TL, Huynh TD, Pham TMH, Nguyen TAT, Nguyen XN, Tran TNT, Truong TNQ, Bui BT, Bui TQ, Ha QT, La CTT, Le PT, Nguyen HD, Nguyen TL, Tran NM.

Int J Cardiol Heart Vasc. 2019 Mar 7;22:169-173. doi: 10.1016/j.ijcha.2019.02.010. eCollection 2019 Mar.


Global lessons from deaths from heart failure in UK hospitals.

Anderson LJ, Squire IB, Cowie MR.

Heart. 2019 Jun;105(12):902-903. doi: 10.1136/heartjnl-2018-314641. Epub 2019 Mar 2. No abstract available.


Preventing Heart Failure at the Population Level: Conventional Cardiovascular Risk Factor Management Should Continue.

Cowie MR, Zakeri R.

JACC Heart Fail. 2019 Mar;7(3):214-216. doi: 10.1016/j.jchf.2018.11.002. No abstract available.


Frailty and co-morbidity predict first hospitalisation after heart failure diagnosis in primary care: population-based observational study in England.

Bottle A, Kim D, Hayhoe B, Majeed A, Aylin P, Clegg A, Cowie MR.

Age Ageing. 2019 May 1;48(3):347-354. doi: 10.1093/ageing/afy194.


Real-world costs of transvenous lead extraction: the challenge for reimbursement.

Brough CEP, Rao A, Haycox AR, Cowie MR, Wright DJ.

Europace. 2019 Feb 1;21(2):290-297. doi: 10.1093/europace/euy291.


Adherence to guidelines in management of symptoms suggestive of heart failure in primary care.

Hayhoe B, Kim D, Aylin PP, Majeed FA, Cowie MR, Bottle A.

Heart. 2019 May;105(9):678-685. doi: 10.1136/heartjnl-2018-313971. Epub 2018 Dec 4.


Real-world presentation with heart failure in primary care: do patients selected to follow diagnostic and management guidelines have better outcomes?

Bottle A, Kim D, Aylin PP, Majeed FA, Cowie MR, Hayhoe B.

Open Heart. 2018 Nov 10;5(2):e000935. doi: 10.1136/openhrt-2018-000935. eCollection 2018.


Withdrawal of pharmacological treatment for heart failure in patients with recovered dilated cardiomyopathy (TRED-HF): an open-label, pilot, randomised trial.

Halliday BP, Wassall R, Lota AS, Khalique Z, Gregson J, Newsome S, Jackson R, Rahneva T, Wage R, Smith G, Venneri L, Tayal U, Auger D, Midwinter W, Whiffin N, Rajani R, Dungu JN, Pantazis A, Cook SA, Ware JS, Baksi AJ, Pennell DJ, Rosen SD, Cowie MR, Cleland JGF, Prasad SK.

Lancet. 2019 Jan 5;393(10166):61-73. doi: 10.1016/S0140-6736(18)32484-X. Epub 2018 Nov 11.


Absence of Myocardial Fibrosis Predicts Favorable Long-Term Survival in New-Onset Heart Failure.

Gulati A, Japp AG, Raza S, Halliday BP, Jones DA, Newsome S, Ismail NA, Morarji K, Khwaja J, Spath N, Shakespeare C, Kalra PR, Lloyd G, Mathur A, Cleland JGF, Cowie MR, Assomull RG, Pennell DJ, Ismail TF, Prasad SK.

Circ Cardiovasc Imaging. 2018 Sep;11(9):e007722. doi: 10.1161/CIRCIMAGING.118.007722.


Treating central sleep apnoea in heart failure: is pull better than push?

Cowie MR, Gallagher AM, Simonds AK.

Eur J Heart Fail. 2018 Dec;20(12):1755-1759. doi: 10.1002/ejhf.1337. Epub 2018 Oct 23. No abstract available.


Assessing health-related quality of life in heart failure patients attending an outpatient clinic: a pragmatic approach.

Gallagher AM, Lucas R, Cowie MR.

ESC Heart Fail. 2019 Feb;6(1):3-9. doi: 10.1002/ehf2.12363. Epub 2018 Oct 11.


Assessment and interpretation of sleep disordered breathing severity in cardiology: Clinical implications and perspectives.

Linz D, Baumert M, Catcheside P, Floras J, Sanders P, Lévy P, Cowie MR, Doug McEvoy R.

Int J Cardiol. 2018 Nov 15;271:281-288. doi: 10.1016/j.ijcard.2018.04.076. Epub 2018 Jul 23. Review.


Hospitalisation and mortality outcomes of patients with comorbid COPD and heart failure: a systematic review protocol.

Axson EL, Sundaram V, Bloom CI, Bottle A, Cowie MR, Quint JK.

BMJ Open. 2018 Jun 30;8(6):e023058. doi: 10.1136/bmjopen-2018-023058.


Optimization of heart rate lowering therapy in hospitalized patients with heart failure: Insights from the Optimize Heart Failure Care Program.

Lopatin YM, Cowie MR, Grebennikova AA, Sisakian HS, Pagava ZM, Hayrapetyan HG, Abdullaev TA, Voronkov LG, Chesnikova AI, Tseluyko VI, Tarlovskaya EI, Dadashova GM, Berkinbaev SF, Glezer MG, Koziolova NA, Rakisheva AG, Kipiani ZV, Kurlyanskaya AK.

Int J Cardiol. 2018 Jun 1;260:113-117. doi: 10.1016/j.ijcard.2017.12.093.


Associations of Obstructive Sleep Apnea With Atrial Fibrillation and Continuous Positive Airway Pressure Treatment: A Review.

Linz D, McEvoy RD, Cowie MR, Somers VK, Nattel S, Lévy P, Kalman JM, Sanders P.

JAMA Cardiol. 2018 Jun 1;3(6):532-540. doi: 10.1001/jamacardio.2018.0095. Review.


Preventing stroke in patients with heart failure: why are patients losing out?

Cowie MR, Zakeri R.

Heart. 2018 Jul;104(13):1050-1052. doi: 10.1136/heartjnl-2017-312862. Epub 2018 Feb 2. No abstract available.


Heart failure with preserved ejection fraction: controversies, challenges and future directions.

Zakeri R, Cowie MR.

Heart. 2018 Mar;104(5):377-384. doi: 10.1136/heartjnl-2016-310790. Epub 2018 Jan 5. Review.


Cost-effectiveness of sacubitril/valsartan in the treatment of heart failure with reduced ejection fraction.

McMurray JJV, Trueman D, Hancock E, Cowie MR, Briggs A, Taylor M, Mumby-Croft J, Woodcock F, Lacey M, Haroun R, Deschaseaux C.

Heart. 2018 Jun;104(12):1006-1013. doi: 10.1136/heartjnl-2016-310661. Epub 2017 Dec 21.


Adaptive servo-ventilation for central sleep apnoea in systolic heart failure: results of the major substudy of SERVE-HF.

Cowie MR, Woehrle H, Wegscheider K, Vettorazzi E, Lezius S, Koenig W, Weidemann F, Smith G, Angermann C, d'Ortho MP, Erdmann E, Levy P, Simonds AK, Somers VK, Zannad F, Teschler H.

Eur J Heart Fail. 2018 Mar;20(3):536-544. doi: 10.1002/ejhf.1048. Epub 2017 Nov 30.


The search for cardiovascular benefit from treating obstructive sleep apnoea with CPAP therapy.

Cowie MR, Gallagher AM, Simonds AK.

Eur Heart J. 2018 Jun 21;39(24):2298-2300. doi: 10.1093/eurheartj/ehx678. No abstract available.


Remote monitoring for heart failure: the story moves on.

Harper AR, Cowie MR.

Eur Heart J. 2017 Feb 1;38(5):310-311. doi: 10.1093/eurheartj/ehw651. No abstract available.


Routes to diagnosis of heart failure: observational study using linked data in England.

Bottle A, Kim D, Aylin P, Cowie MR, Majeed A, Hayhoe B.

Heart. 2018 Apr;104(7):600-605. doi: 10.1136/heartjnl-2017-312183. Epub 2017 Oct 5.


Cost-Effectiveness Analysis of Natriuretic Peptide Testing and Specialist Management in Patients with Suspected Acute Heart Failure.

Griffin EA, Wonderling D, Ludman AJ, Al-Mohammad A, Cowie MR, Hardman SMC, McMurray JJV, Kendall J, Mitchell P, Shote A, Dworzynski K, Mant J.

Value Health. 2017 Sep;20(8):1025-1033. doi: 10.1016/j.jval.2017.05.007. Epub 2017 Jul 11.


Sleep Disordered Breathing and Heart Failure: What Does the Future Hold?

Cowie MR, Gallagher AM.

JACC Heart Fail. 2017 Oct;5(10):715-723. doi: 10.1016/j.jchf.2017.06.016. Epub 2017 Sep 6. Review.


Adaptive servo ventilation for central sleep apnoea in heart failure: SERVE-HF on-treatment analysis.

Woehrle H, Cowie MR, Eulenburg C, Suling A, Angermann C, d'Ortho MP, Erdmann E, Levy P, Simonds AK, Somers VK, Zannad F, Teschler H, Wegscheider K.

Eur Respir J. 2017 Aug 31;50(2). pii: 1601692. doi: 10.1183/13993003.01692-2016. Print 2017 Aug.


Report from the Annual Conference of the British Society of Echocardiography, November 2016, Queen Elizabeth II Conference Centre, London.

Steeds RP, Cowie MR, Rana BS, Chambers JB, Ray S, Srinivasan J, Schwarz K, Neil CJ, Scally C, Horowitz JD, Frenneaux MP, Pislaru C, Dawson DK, Rothwell OJ, George K, Somauroo JD, Lord R, Stembridge M, Shave R, Hoffman M, Ashley EA, Haddad F, Eijsvogels TMH, Oxborough D, Hampson R, Kinsey CD, Gurunathan S, Vamvakidou A, Karogiannis N, Senior R, Ahmadvazir S, Shah BN, Zacharias K, Bowen D, Robinson S, Ihekwaba U, Parker K, Boyd J, Densem CG, Atkinson C, Hinton J, Gaisie EB, Rakhit DJ, Yue AM, Roberts PR, Thomas D, Phen P, Sibley J, Fergey S, Russhard P.

Echo Res Pract. 2017 Sep 1;4(3):M1. doi: 10.1530/ERP-17-0046. No abstract available.


Development and validation of a novel non-contact monitor of nocturnal respiration for identifying sleep-disordered breathing in patients with heart failure.

Savage HO, Khushaba RN, Zaffaroni A, Colefax M, Farrugia S, Schindhelm K, Teschler H, Weinreich G, Grueger H, Neddermann M, Heneghan C, Simonds A, Cowie MR.

ESC Heart Fail. 2016 Sep;3(3):212-219. doi: 10.1002/ehf2.12086. Epub 2016 Mar 1.


Remote management of heart failure using implantable electronic devices.

Morgan JM, Kitt S, Gill J, McComb JM, Ng GA, Raftery J, Roderick P, Seed A, Williams SG, Witte KK, Wright DJ, Harris S, Cowie MR.

Eur Heart J. 2017 Aug 7;38(30):2352-2360. doi: 10.1093/eurheartj/ehx227.


Physicians' guideline adherence is associated with better prognosis in outpatients with heart failure with reduced ejection fraction: the QUALIFY international registry.

Komajda M, Cowie MR, Tavazzi L, Ponikowski P, Anker SD, Filippatos GS; QUALIFY Investigators.

Eur J Heart Fail. 2017 Nov;19(11):1414-1423. doi: 10.1002/ejhf.887. Epub 2017 Apr 30.


Expert consensus document: Echocardiography and lung ultrasonography for the assessment and management of acute heart failure.

Price S, Platz E, Cullen L, Tavazzi G, Christ M, Cowie MR, Maisel AS, Masip J, Miro O, McMurray JJ, Peacock WF, Martin-Sanchez FJ, Di Somma S, Bueno H, Zeymer U, Mueller C; Acute Heart Failure Study Group of the European Society of Cardiology Acute Cardiovascular Care Association.

Nat Rev Cardiol. 2017 Jul;14(7):427-440. doi: 10.1038/nrcardio.2017.56. Epub 2017 Apr 27. Review.


Assessing the Eligibility Criteria in Phase III Randomized Controlled Trials of Drug Therapy in Heart Failure With Preserved Ejection Fraction: The Critical Play-Off Between a "Pure" Patient Phenotype and the Generalizability of Trial Findings.

Patel HC, Hayward C, Dungu JN, Papadopoulou S, Saidmeerasah A, Ray R, Di Mario C, Shanmugam N, Cowie MR, Anderson LJ.

J Card Fail. 2017 Jul;23(7):517-524. doi: 10.1016/j.cardfail.2017.04.006. Epub 2017 Apr 18.


Sleepiness and activity in heart failure patients with reduced ejection fraction and central sleep-disordered breathing.

Atalla A, Carlisle TW, Simonds AK, Cowie MR, Morrell MJ.

Sleep Med. 2017 Jun;34:217-223. doi: 10.1016/j.sleep.2016.11.022. Epub 2017 Jan 23.


Withdrawing ASV therapy in clinical practice: trials and tribulations.

Cowie MR.

Sleep Med. 2017 Sep;37:208-209. doi: 10.1016/j.sleep.2017.03.001. Epub 2017 Mar 9. No abstract available.


Association Between Midwall Late Gadolinium Enhancement and Sudden Cardiac Death in Patients With Dilated Cardiomyopathy and Mild and Moderate Left Ventricular Systolic Dysfunction.

Halliday BP, Gulati A, Ali A, Guha K, Newsome S, Arzanauskaite M, Vassiliou VS, Lota A, Izgi C, Tayal U, Khalique Z, Stirrat C, Auger D, Pareek N, Ismail TF, Rosen SD, Vazir A, Alpendurada F, Gregson J, Frenneaux MP, Cowie MR, Cleland JGF, Cook SA, Pennell DJ, Prasad SK.

Circulation. 2017 May 30;135(22):2106-2115. doi: 10.1161/CIRCULATIONAHA.116.026910. Epub 2017 Mar 28.


New medicinal products for chronic heart failure: advances in clinical trial design and efficacy assessment.

Cowie MR, Filippatos GS, Alonso Garcia MLA, Anker SD, Baczynska A, Bloomfield DM, Borentain M, Bruins Slot K, Cronin M, Doevendans PA, El-Gazayerly A, Gimpelewicz C, Honarpour N, Janmohamed S, Janssen H, Kim AM, Lautsch D, Laws I, Lefkowitz M, Lopez-Sendon J, Lyon AR, Malik FI, McMurray JJV, Metra M, Figueroa Perez S, Pfeffer MA, Pocock SJ, Ponikowski P, Prasad K, Richard-Lordereau I, Roessig L, Rosano GMC, Sherman W, Stough WG, Swedberg K, Tyl B, Zannad F, Boulton C, De Graeff P.

Eur J Heart Fail. 2017 Jun;19(6):718-727. doi: 10.1002/ejhf.809. Epub 2017 Mar 27. Review.

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