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Items: 1 to 50 of 75

1.

Eating pathology and psychological outcomes in young adults in self-regulation interventions using daily self-weighing.

Gorin AA, Gokee LaRose J, Espeland MA, Tate DF, Jelalian E, Robichaud E, Coward P, Hatley KE, Garcia KR, Lang W, Bahnson J, Lewis CE, Wing RR.

Health Psychol. 2019 Feb;38(2):143-150. doi: 10.1037/hea0000689. Epub 2018 Dec 13.

PMID:
30550313
2.

Mild Illness during Outbreak of Shiga Toxin-Producing Escherichia coli O157 Infections Associated with Agricultural Show, Australia.

Vasant BR, Stafford RJ, Jennison AV, Bennett SM, Bell RJ, Doyle CJ, Young JR, Vlack SA, Titmus P, El Saadi D, Jarvinen KAJ, Coward P, Barrett J, Staples M, Graham RMA, Smith HV, Lambert SB.

Emerg Infect Dis. 2017 Oct;23(10):1686-1689. doi: 10.3201/eid2310.161836.

3.

Novel Series of Potent Glucokinase Activators Leading to the Discovery of AM-2394.

Dransfield PJ, Pattaropong V, Lai S, Fu Z, Kohn TJ, Du X, Cheng A, Xiong Y, Komorowski R, Jin L, Conn M, Tien E, DeWolf WE Jr, Hinklin RJ, Aicher TD, Kraser CF, Boyd SA, Voegtli WC, Condroski KR, Veniant-Ellison M, Medina JC, Houze J, Coward P.

ACS Med Chem Lett. 2016 May 23;7(7):714-8. doi: 10.1021/acsmedchemlett.6b00140. eCollection 2016 Jul 14.

4.

5-Alkyl-2-urea-Substituted Pyridines: Identification of Efficacious Glucokinase Activators with Improved Properties.

Kohn TJ, Du X, Lai S, Xiong Y, Komorowski R, Veniant M, Fu Z, Jiao X, Pattaropong V, Chow D, Cardozo M, Jin L, Conn M, DeWolf WE Jr, Kraser CF, Hinklin RJ, Boys ML, Medina JC, Houze J, Dransfield P, Coward P.

ACS Med Chem Lett. 2016 Jun 1;7(7):666-70. doi: 10.1021/acsmedchemlett.6b00145. eCollection 2016 Jul 14.

5.

A pilot randomized controlled trial testing the effects of a routine-based intervention on outcomes in a behavioural weight loss programme.

Demos KE, Leahey TM, Hart CN, Trautvetter J, Coward PR, Duszlak J, Wing RR.

Obes Sci Pract. 2015 Dec 10;1(2):110-118. doi: 10.1002/osp4.16. eCollection 2015 Dec.

6.

C5-Alkyl-2-methylurea-Substituted Pyridines as a New Class of Glucokinase Activators.

Du X, Hinklin RJ, Xiong Y, Dransfield P, Park J, Kohn TJ, Pattaropong V, Lai S, Fu Z, Jiao X, Chow D, Jin L, Davda J, Veniant MM, Anderson DA, Baer BR, Bencsik JR, Boyd SA, Chicarelli MJ, Mohr PJ, Wang B, Condroski KR, DeWolf WE, Conn M, Tran T, Yang J, Aicher TD, Medina JC, Coward P, Houze JB.

ACS Med Chem Lett. 2014 Nov 22;5(12):1284-9. doi: 10.1021/ml500341w. eCollection 2014 Dec 11.

7.

Failure to replicate depletion of self-control.

Xu X, Demos KE, Leahey TM, Hart CN, Trautvetter J, Coward P, Middleton KR, Wing RR.

PLoS One. 2014 Oct 21;9(10):e109950. doi: 10.1371/journal.pone.0109950. eCollection 2014.

8.

Structure-assisted discovery of the first non-retinoid ligands for Retinol-Binding Protein 4.

Wang Y, Connors R, Fan P, Wang X, Wang Z, Liu J, Kayser F, Medina JC, Johnstone S, Xu H, Thibault S, Walker N, Conn M, Zhang Y, Liu Q, Grillo MP, Motani A, Coward P, Wang Z.

Bioorg Med Chem Lett. 2014 Jul 1;24(13):2885-91. doi: 10.1016/j.bmcl.2014.04.089. Epub 2014 May 2.

PMID:
24835984
9.

Characterization of a novel glucokinase activator in rat and mouse models.

Lu M, Li P, Bandyopadhyay G, Lagakos W, Dewolf WE Jr, Alford T, Chicarelli MJ, Williams L, Anderson DA, Baer BR, McVean M, Conn M, VĂ©niant MM, Coward P.

PLoS One. 2014 Feb 12;9(2):e88431. doi: 10.1371/journal.pone.0088431. eCollection 2014.

10.

Discovery and optimization of 5-(2-((1-(phenylsulfonyl)-1,2,3,4-tetrahydroquinolin-7-yl)oxy)pyridin-4-yl)-1,2,4-oxadiazoles as novel gpr119 agonists.

Wang Y, Yu M, Zhu J, Zhang JK, Kayser F, Medina JC, Siegler K, Conn M, Shan B, Grillo MP, Liu JJ, Coward P.

Bioorg Med Chem Lett. 2014 Feb 15;24(4):1133-7. doi: 10.1016/j.bmcl.2013.12.127. Epub 2014 Jan 8.

PMID:
24440299
11.

Discovery and optimization of N-(3-(1,3-dioxo-2,3-dihydro-1H-pyrrolo[3,4-c]pyridin-4-yloxy)phenyl)benzenesulfonamides as novel GPR119 agonists.

Yu M, Ken Zhang J, Wang Y, Zhu J, Kayser F, Medina JC, Siegler K, Conn M, Shan B, Grillo MP, Coward P, Jim Liu J.

Bioorg Med Chem Lett. 2014 Jan 1;24(1):156-60. doi: 10.1016/j.bmcl.2013.11.053. Epub 2013 Dec 1.

PMID:
24332491
12.

Discovery and optimization of arylsulfonyl 3-(pyridin-2-yloxy)anilines as novel GPR119 agonists.

Zhang JK, Li AR, Yu M, Wang Y, Zhu J, Kayser F, Medina JC, Siegler K, Conn M, Shan B, Grillo MP, Eksterowicz J, Coward P, Liu JJ.

Bioorg Med Chem Lett. 2013 Jun 15;23(12):3609-13. doi: 10.1016/j.bmcl.2013.04.014. Epub 2013 Apr 15.

PMID:
23648181
13.

Discovery and optimization of a series of liver X receptor antagonists.

Jiao X, Kopecky DJ, Fisher B, Piper DE, Labelle M, McKendry S, Harrison M, Jones S, Jaen J, Shiau AK, Escaron P, Danao J, Chai A, Coward P, Kayser F.

Bioorg Med Chem Lett. 2012 Sep 15;22(18):5966-70. doi: 10.1016/j.bmcl.2012.07.048. Epub 2012 Jul 21.

PMID:
22901900
14.

Fracture of a ceramic component in total hip replacement.

Whittingham-Jones P, Mann B, Coward P, Hart AJ, Skinner JA.

J Bone Joint Surg Br. 2012 Apr;94(4):570-3. doi: 10.1302/0301-620X.94B4.28013.

PMID:
22434477
15.

Discovery of a new binding mode for a series of liver X receptor agonists.

Kopecky DJ, Jiao XY, Fisher B, McKendry S, Labelle M, Piper DE, Coward P, Shiau AK, Escaron P, Danao J, Chai A, Jaen J, Kayser F.

Bioorg Med Chem Lett. 2012 Apr 1;22(7):2407-10. doi: 10.1016/j.bmcl.2012.02.028. Epub 2012 Feb 20.

PMID:
22406115
16.

Developing strategies to enhance health services research capacity in a predominantly rural Canadian health authority.

Miller J, Bryant Maclean L, Coward P, Broemeling AM.

Rural Remote Health. 2009 Oct-Dec;9(4):1266. Epub 2009 Dec 21.

17.

Discovery and optimization of a novel Neuromedin B receptor antagonist.

Fu J, Shuttleworth SJ, Connors RV, Chai A, Coward P.

Bioorg Med Chem Lett. 2009 Aug 1;19(15):4264-7. doi: 10.1016/j.bmcl.2009.05.124. Epub 2009 Jun 6.

PMID:
19553112
18.

Identification of a PPARdelta agonist with partial agonistic activity on PPARgamma.

Connors RV, Wang Z, Harrison M, Zhang A, Wanska M, Hiscock S, Fox B, Dore M, Labelle M, Sudom A, Johnstone S, Liu J, Walker NP, Chai A, Siegler K, Li Y, Coward P.

Bioorg Med Chem Lett. 2009 Jul 1;19(13):3550-4. doi: 10.1016/j.bmcl.2009.04.151. Epub 2009 May 9.

PMID:
19464171
19.

Identification and characterization of a non-retinoid ligand for retinol-binding protein 4 which lowers serum retinol-binding protein 4 levels in vivo.

Motani A, Wang Z, Conn M, Siegler K, Zhang Y, Liu Q, Johnstone S, Xu H, Thibault S, Wang Y, Fan P, Connors R, Le H, Xu G, Walker N, Shan B, Coward P.

J Biol Chem. 2009 Mar 20;284(12):7673-80. doi: 10.1074/jbc.M809654200. Epub 2009 Jan 15.

20.

Application of an allosteric model to describe the interactions among retinol binding protein 4, transthyretin, and small molecule retinol binding protein 4 ligands.

Coward P, Conn M, Tang J, Xiong F, Menjares A, Reagan JD.

Anal Biochem. 2009 Jan 15;384(2):312-20. doi: 10.1016/j.ab.2008.09.051. Epub 2008 Oct 12.

PMID:
18952041
21.

Effect of ultrasonic debridement using a chlorhexidine irrigant on circulating levels of lipopolysaccharides and interleukin-6.

Lee MK, Ide M, Coward PY, Wilson RF.

J Clin Periodontol. 2008 May;35(5):415-9. doi: 10.1111/j.1600-051X.2008.01221.x. Epub 2008 Mar 13.

PMID:
18341600
22.
23.

Investigation of periodontal destruction patterns in smokers and non-smokers.

Baharin B, Palmer RM, Coward P, Wilson RF.

J Clin Periodontol. 2006 Jul;33(7):485-90.

PMID:
16820036
24.

The effect of a commercially available chlorhexidine mouthwash product on human osteoblast cells.

Patel P, Ide M, Coward P, Di Silvio L.

Eur J Prosthodont Restor Dent. 2006 Jun;14(2):67-72.

PMID:
16808107
25.

A review of information management practices for health ministries.

Lau F, Protti D, Coward P.

Healthc Manage Forum. 2005 Summer;18(2):14-21. Review.

PMID:
16119382
26.

The influence of vitamin C on systemic markers of endothelial and inflammatory cell activation in smokers and non-smokers.

Scott DA, Poston RN, Wilson RF, Coward PY, Palmer RM.

Inflamm Res. 2005 Mar;54(3):138-44.

PMID:
15883748
27.

A retrospective study of periodontal disease severity in smokers and non-smokers.

Razali M, Palmer RM, Coward P, Wilson RF.

Br Dent J. 2005 Apr 23;198(8):495-8; discussion 485.

PMID:
15849588
28.

Effects of peroxisome proliferator-activated receptor alpha/delta agonists on HDL-cholesterol in vervet monkeys.

Wallace JM, Schwarz M, Coward P, Houze J, Sawyer JK, Kelley KL, Chai A, Rudel LL.

J Lipid Res. 2005 May;46(5):1009-16. Epub 2005 Feb 16.

29.

A prospective study to investigate the relationship between periodontal disease and adverse pregnancy outcome.

Moore S, Ide M, Coward PY, Randhawa M, Borkowska E, Baylis R, Wilson RF.

Br Dent J. 2004 Sep 11;197(5):251-8; discussion 247.

PMID:
15359324
30.

Identification and optimization of novel partial agonists of neuromedin B receptor using parallel synthesis.

Shuttleworth SJ, Lizarzaburu ME, Chai A, Coward P.

Bioorg Med Chem Lett. 2004 Jun 21;14(12):3037-42.

PMID:
15149640
31.
32.

Introducing a technology-enabled problem-based learning approach into a health informatics curriculum.

Green CJ, van Gyn GH, Moehr JR, Lau FY, Coward PM.

Int J Med Inform. 2004 Mar 18;73(2):173-9.

PMID:
15063377
33.

Orphan nuclear receptors: from new ligand discovery technologies to novel signaling pathways.

Shiau AK, Coward P, Schwarz M, Lehmann JM.

Curr Opin Drug Discov Devel. 2001 Sep;4(5):575-90. Review.

PMID:
12825453
34.

Effect of treatment of chronic periodontitis on levels of serum markers of acute-phase inflammatory and vascular responses.

Ide M, McPartlin D, Coward PY, Crook M, Lumb P, Wilson RF.

J Clin Periodontol. 2003 Apr;30(4):334-40.

PMID:
12694432
35.

Recrudescent herpes labialis during and prior to early pregnancy.

Scott D, Moore S, Ide M, Coward P, Baylis R, Borkowska E.

Int J Gynaecol Obstet. 2003 Mar;80(3):263-9.

PMID:
12628527
36.

Effect of nicotine replacement and quitting smoking on circulating adhesion molecule profiles (sICAM-1, sCD44v5, sCD44v6).

Palmer RM, Stapleton JA, Sutherland G, Coward PY, Wilson RF, Scott DA.

Eur J Clin Invest. 2002 Nov;32(11):852-7.

PMID:
12423327
37.

A simple method for the estimation of the bioavailability of radiocaesium from herbage contaminated by adherent soil.

Beresford NA, Barnett CL, Coward PA, Howard BJ, Mayes RW.

J Environ Radioact. 2002;63(1):77-84.

PMID:
12230137
38.

Periodontal health of London women during early pregnancy.

Moore S, Ide M, Wilson RF, Coward PY, Borkowska E, Baylis R, Bewley S, Maxwell DJ, Mulhair L, Ashley FP.

Br Dent J. 2001 Nov 24;191(10):570-3.

39.

Analysis of circulating insulin-like growth factor-1 (IGF-1) and IGF binding protein-3 (IGFBP-3) in tobacco smokers and non-smokers.

Palmer RM, Wilson RF, Coward PY, Scott DA.

Tob Induc Dis. 2002 Jun 15;1(2):157-70. doi: 10.1186/1617-9625-1-2-157.

40.

Comparison of the erosive potential of gastric juice and a carbonated drink in vitro.

Bartlett DW, Coward PY.

J Oral Rehabil. 2001 Nov;28(11):1045-7.

PMID:
11722721
41.

Tools for dissecting signaling pathways in vivo: receptors activated solely by synthetic ligands.

Scearce-Levie K, Coward P, Redfern CH, Conklin BR.

Methods Enzymol. 2002;343:232-48. No abstract available.

PMID:
11665570
42.
43.
44.

Engineering receptors activated solely by synthetic ligands (RASSLs).

Scearce-Levie K, Coward P, Redfern CH, Conklin BR.

Trends Pharmacol Sci. 2001 Aug;22(8):414-20.

PMID:
11479004
45.

4-Hydroxytamoxifen binds to and deactivates the estrogen-related receptor gamma.

Coward P, Lee D, Hull MV, Lehmann JM.

Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8880-4. Epub 2001 Jul 10.

46.

Plasma concentrations of reputed tumor-associated soluble CD44 isoforms (v5 and v6) in smokers are dose related and decline on smoking cessation.

Scott DA, Stapleton JA, Palmer RM, Wilson RF, Sutherland G, Coward PY, Gustavsson G, Odell EW, Poston RN.

Cancer Epidemiol Biomarkers Prev. 2000 Nov;9(11):1211-4.

47.

Dramatic decline in circulating intercellular adhesion molecule-1 concentration on quitting tobacco smoking.

Scott DA, Stapleton JA, Wilson RF, Sutherland G, Palmer RM, Coward PY, Gustavsson G.

Blood Cells Mol Dis. 2000 Jun;26(3):255-8.

PMID:
10950946
48.

Conditional expression of a Gi-coupled receptor causes ventricular conduction delay and a lethal cardiomyopathy.

Redfern CH, Degtyarev MY, Kwa AT, Salomonis N, Cotte N, Nanevicz T, Fidelman N, Desai K, Vranizan K, Lee EK, Coward P, Shah N, Warrington JA, Fishman GI, Bernstein D, Baker AJ, Conklin BR.

Proc Natl Acad Sci U S A. 2000 Apr 25;97(9):4826-31.

49.

The acute influence of tobacco smoking on adhesion molecule expression on monocytes and neutrophils and on circulating adhesion molecule levels in vivo.

Scott DA, Todd DH, Coward PY, Wilson RF, Odell EW, Poston RN, Matthews JP, Palmer RM.

Addict Biol. 2000 Apr 1;5(2):195-205. doi: 10.1080/13556210050003793.

PMID:
20575835
50.

Serum concentration of total soluble CD44 is elevated in smokers.

Scott DA, Coward PY, Wilson RF, Poston RN, Odell EW, Palmer RM.

Biomarkers. 2000;5(3):240-4. doi: 10.1080/135475000230406.

PMID:
23889226

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