Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 52


The activity-regulated cytoskeleton-associated protein, Arc/Arg3.1, influences mouse cocaine self-administration.

Penrod RD, Thomsen M, Taniguchi M, Guo Y, Cowan CW, Smith LN.

Pharmacol Biochem Behav. 2020 Jan;188:172818. doi: 10.1016/j.pbb.2019.172818. Epub 2019 Nov 1.


Emerging roles for MEF2 in brain development and mental disorders.

Assali A, Harrington AJ, Cowan CW.

Curr Opin Neurobiol. 2019 Dec;59:49-58. doi: 10.1016/j.conb.2019.04.008. Epub 2019 May 23. Review.


Activity-regulated cytoskeleton-associated protein (Arc/Arg3.1) regulates anxiety- and novelty-related behaviors.

Penrod RD, Kumar J, Smith LN, McCalley D, Nentwig TB, Hughes BW, Barry GM, Glover K, Taniguchi M, Cowan CW.

Genes Brain Behav. 2019 Sep;18(7):e12561. doi: 10.1111/gbb.12561. Epub 2019 Apr 15.


Knockdown of the histone di-methyltransferase G9a in nucleus accumbens shell decreases cocaine self-administration, stress-induced reinstatement, and anxiety.

Anderson EM, Sun H, Guzman D, Taniguchi M, Cowan CW, Maze I, Nestler EJ, Self DW.

Neuropsychopharmacology. 2019 Jul;44(8):1370-1376. doi: 10.1038/s41386-018-0305-4. Epub 2018 Dec 26.


It is a complex issue: emerging connections between epigenetic regulators in drug addiction.

Anderson EM, Penrod RD, Barry SM, Hughes BW, Taniguchi M, Cowan CW.

Eur J Neurosci. 2019 Aug;50(3):2477-2491. doi: 10.1111/ejn.14170. Epub 2018 Oct 10. Review.


Any Way You Splice It: New Molecular Mechanisms of Cocaine-Induced Alternative Gene Expression.

Penrod RD, Anderson EM, Cowan CW.

Biol Psychiatry. 2018 Aug 1;84(3):162-164. doi: 10.1016/j.biopsych.2018.06.004. Epub 2018 Jun 22. No abstract available.


Role of Dorsal Striatum Histone Deacetylase 5 in Incubation of Methamphetamine Craving.

Li X, Carreria MB, Witonsky KR, Zeric T, Lofaro OM, Bossert JM, Zhang J, Surjono F, Richie CT, Harvey BK, Son H, Cowan CW, Nestler EJ, Shaham Y.

Biol Psychiatry. 2018 Aug 1;84(3):213-222. doi: 10.1016/j.biopsych.2017.12.008. Epub 2017 Dec 29.


Inactivation of NMDA Receptors in the Ventral Tegmental Area during Cocaine Self-Administration Prevents GluA1 Upregulation but with Paradoxical Increases in Cocaine-Seeking Behavior.

Guzman D, Carreira MB, Friedman AK, Adachi M, Neve RL, Monteggia LM, Han MH, Cowan CW, Self DW.

J Neurosci. 2018 Jan 17;38(3):575-585. doi: 10.1523/JNEUROSCI.2828-16.2017. Epub 2017 Dec 1.


HDAC5 and Its Target Gene, Npas4, Function in the Nucleus Accumbens to Regulate Cocaine-Conditioned Behaviors.

Taniguchi M, Carreira MB, Cooper YA, Bobadilla AC, Heinsbroek JA, Koike N, Larson EB, Balmuth EA, Hughes BW, Penrod RD, Kumar J, Smith LN, Guzman D, Takahashi JS, Kim TK, Kalivas PW, Self DW, Lin Y, Cowan CW.

Neuron. 2017 Sep 27;96(1):130-144.e6. doi: 10.1016/j.neuron.2017.09.015.


BDNF-TrkB controls cocaine-induced dendritic spines in rodent nucleus accumbens dissociated from increases in addictive behaviors.

Anderson EM, Wissman AM, Chemplanikal J, Buzin N, Guzman D, Larson EB, Neve RL, Nestler EJ, Cowan CW, Self DW.

Proc Natl Acad Sci U S A. 2017 Aug 29;114(35):9469-9474. doi: 10.1073/pnas.1702441114. Epub 2017 Aug 14.


Novel role and regulation of HDAC4 in cocaine-related behaviors.

Penrod RD, Carreira MB, Taniguchi M, Kumar J, Maddox SA, Cowan CW.

Addict Biol. 2018 Mar;23(2):653-664. doi: 10.1111/adb.12522. Epub 2017 Jun 21.


MEF2C regulates cortical inhibitory and excitatory synapses and behaviors relevant to neurodevelopmental disorders.

Harrington AJ, Raissi A, Rajkovich K, Berto S, Kumar J, Molinaro G, Raduazzo J, Guo Y, Loerwald K, Konopka G, Huber KM, Cowan CW.

Elife. 2016 Oct 25;5. pii: e20059. doi: 10.7554/eLife.20059.


Assessment of Cocaine-induced Behavioral Sensitization and Conditioned Place Preference in Mice.

Smith LN, Penrod RD, Taniguchi M, Cowan CW.

J Vis Exp. 2016 Feb 18;(108):53107. doi: 10.3791/53107.


Use of Adeno-Associated and Herpes Simplex Viral Vectors for In Vivo Neuronal Expression in Mice.

Penrod RD, Wells AM, Carlezon WA Jr, Cowan CW.

Curr Protoc Neurosci. 2015 Oct 1;73:4.37.1-4.37.31. doi: 10.1002/0471142301.ns0437s73.


EphB1 and EphB2 intracellular domains regulate the formation of the corpus callosum and anterior commissure.

Robichaux MA, Chenaux G, Ho HY, Soskis MJ, Greenberg ME, Henkemeyer M, Cowan CW.

Dev Neurobiol. 2016 Apr;76(4):405-20. doi: 10.1002/dneu.22323. Epub 2015 Jul 16.


Fragile X mental retardation protein regulates synaptic and behavioral plasticity to repeated cocaine administration.

Smith LN, Jedynak JP, Fontenot MR, Hale CF, Dietz KC, Taniguchi M, Thomas FS, Zirlin BC, Birnbaum SG, Huber KM, Thomas MJ, Cowan CW.

Neuron. 2014 May 7;82(3):645-58. doi: 10.1016/j.neuron.2014.03.028.


EphB receptor forward signaling regulates area-specific reciprocal thalamic and cortical axon pathfinding.

Robichaux MA, Chenaux G, Ho HY, Soskis MJ, Dravis C, Kwan KY, Ε estan N, Greenberg ME, Henkemeyer M, Cowan CW.

Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2188-93. doi: 10.1073/pnas.1324215111. Epub 2014 Jan 22.


Signaling mechanisms of axon guidance and early synaptogenesis.

Robichaux MA, Cowan CW.

Curr Top Behav Neurosci. 2014;16:19-48. doi: 10.1007/7854_2013_255. Review.


Striking a balance in fragile X.

Smith LN, Cowan CW.

Nat Med. 2013 Nov;19(11):1370-1. doi: 10.1038/nm.3383. No abstract available.


Postsynaptic FMRP bidirectionally regulates excitatory synapses as a function of developmental age and MEF2 activity.

Zang T, Maksimova MA, Cowan CW, Bassel-Duby R, Olson EN, Huber KM.

Mol Cell Neurosci. 2013 Sep;56:39-49. doi: 10.1016/j.mcn.2013.03.002. Epub 2013 Mar 17.


Emerging roles of actin cytoskeleton regulating enzymes in drug addiction: actin or reactin'?

Rothenfluh A, Cowan CW.

Curr Opin Neurobiol. 2013 Aug;23(4):507-12. doi: 10.1016/j.conb.2013.01.027. Epub 2013 Feb 18. Review.


Multiple autism-linked genes mediate synapse elimination via proteasomal degradation of a synaptic scaffold PSD-95.

Tsai NP, Wilkerson JR, Guo W, Maksimova MA, DeMartino GN, Cowan CW, Huber KM.

Cell. 2012 Dec 21;151(7):1581-94. doi: 10.1016/j.cell.2012.11.040.


EphB2 receptor forward signaling controls cortical growth cone collapse via Nck and Pak.

Srivastava N, Robichaux MA, Chenaux G, Henkemeyer M, Cowan CW.

Mol Cell Neurosci. 2013 Jan;52:106-16. doi: 10.1016/j.mcn.2012.11.003. Epub 2012 Nov 10.


A chemical genetic approach reveals distinct EphB signaling mechanisms during brain development.

Soskis MJ, Ho HY, Bloodgood BL, Robichaux MA, Malik AN, Ataman B, Rubin AA, Zieg J, Zhang C, Shokat KM, Sharma N, Cowan CW, Greenberg ME.

Nat Neurosci. 2012 Dec;15(12):1645-54. doi: 10.1038/nn.3249. Epub 2012 Nov 11.


Plexins are GTPase-activating proteins for Rap and are activated by induced dimerization.

Wang Y, He H, Srivastava N, Vikarunnessa S, Chen YB, Jiang J, Cowan CW, Zhang X.

Sci Signal. 2012 Jan 17;5(207):ra6. doi: 10.1126/scisignal.2002636. Erratum in: Sci Signal. 2012 Mar 13;5(215):er2.


Histone deacetylase 5 limits cocaine reward through cAMP-induced nuclear import.

Taniguchi M, Carreira MB, Smith LN, Zirlin BC, Neve RL, Cowan CW.

Neuron. 2012 Jan 12;73(1):108-20. doi: 10.1016/j.neuron.2011.10.032.


Essential role for vav Guanine nucleotide exchange factors in brain-derived neurotrophic factor-induced dendritic spine growth and synapse plasticity.

Hale CF, Dietz KC, Varela JA, Wood CB, Zirlin BC, Leverich LS, Greene RW, Cowan CW.

J Neurosci. 2011 Aug 31;31(35):12426-36. doi: 10.1523/JNEUROSCI.0685-11.2011.


Guidance molecules in synapse formation and plasticity.

Shen K, Cowan CW.

Cold Spring Harb Perspect Biol. 2010 Apr;2(4):a001842. doi: 10.1101/cshperspect.a001842. Epub 2010 Mar 10. Review.


Fragile X mental retardation protein is required for synapse elimination by the activity-dependent transcription factor MEF2.

Pfeiffer BE, Zang T, Wilkerson JR, Taniguchi M, Maksimova MA, Smith LN, Cowan CW, Huber KM.

Neuron. 2010 Apr 29;66(2):191-7. doi: 10.1016/j.neuron.2010.03.017.


Striatal dysregulation of Cdk5 alters locomotor responses to cocaine, motor learning, and dendritic morphology.

Meyer DA, Richer E, Benkovic SA, Hayashi K, Kansy JW, Hale CF, Moy LY, Kim Y, O'Callaghan JP, Tsai LH, Greengard P, Nairn AC, Cowan CW, Miller DB, Antich P, Bibb JA.

Proc Natl Acad Sci U S A. 2008 Nov 25;105(47):18561-6. doi: 10.1073/pnas.0806078105. Epub 2008 Nov 18.


Regulation of synaptic connectivity with chronic cocaine.

Cowan CW, Taniguchi M, Hale CF.

Am J Psychiatry. 2008 Nov;165(11):1393. doi: 10.1176/appi.ajp.2008.08101465. No abstract available.


Cocaine regulates MEF2 to control synaptic and behavioral plasticity.

Pulipparacharuvil S, Renthal W, Hale CF, Taniguchi M, Xiao G, Kumar A, Russo SJ, Sikder D, Dewey CM, Davis MM, Greengard P, Nairn AC, Nestler EJ, Cowan CW.

Neuron. 2008 Aug 28;59(4):621-33. doi: 10.1016/j.neuron.2008.06.020.


Essential role of Vav family guanine nucleotide exchange factors in EphA receptor-mediated angiogenesis.

Hunter SG, Zhuang G, Brantley-Sieders D, Swat W, Cowan CW, Chen J.

Mol Cell Biol. 2006 Jul;26(13):4830-42.


Activity-dependent regulation of MEF2 transcription factors suppresses excitatory synapse number.

Flavell SW, Cowan CW, Kim TK, Greer PL, Lin Y, Paradis S, Griffith EC, Hu LS, Chen C, Greenberg ME.

Science. 2006 Feb 17;311(5763):1008-12.


A novel role for extracellular signal-regulated kinase 5 and myocyte enhancer factor 2 in medulloblastoma cell death.

Sturla LM, Cowan CW, Guenther L, Castellino RC, Kim JY, Pomeroy SL.

Cancer Res. 2005 Jul 1;65(13):5683-9.


Vav family GEFs link activated Ephs to endocytosis and axon guidance.

Cowan CW, Shao YR, Sahin M, Shamah SM, Lin MZ, Greer PL, Gao S, Griffith EC, Brugge JS, Greenberg ME.

Neuron. 2005 Apr 21;46(2):205-17.


Eph-dependent tyrosine phosphorylation of ephexin1 modulates growth cone collapse.

Sahin M, Greer PL, Lin MZ, Poucher H, Eberhart J, Schmidt S, Wright TM, Shamah SM, O'connell S, Cowan CW, Hu L, Goldberg JL, Debant A, Corfas G, Krull CE, Greenberg ME.

Neuron. 2005 Apr 21;46(2):191-204.


Survival factor-mediated BAD phosphorylation raises the mitochondrial threshold for apoptosis.

Datta SR, Ranger AM, Lin MZ, Sturgill JF, Ma YC, Cowan CW, Dikkes P, Korsmeyer SJ, Greenberg ME.

Dev Cell. 2002 Nov;3(5):631-43.


CREB transcriptional activity in neurons is regulated by multiple, calcium-specific phosphorylation events.

Kornhauser JM, Cowan CW, Shaywitz AJ, Dolmetsch RE, Griffith EC, Hu LS, Haddad C, Xia Z, Greenberg ME.

Neuron. 2002 Apr 11;34(2):221-33.


Dependence of RGS9-1 membrane attachment on its C-terminal tail.

He W, Melia TJ, Cowan CW, Wensel TG.

J Biol Chem. 2001 Dec 28;276(52):48961-6. Epub 2001 Oct 24.


REST acts through multiple deacetylase complexes.

Griffith EC, Cowan CW, Greenberg ME.

Neuron. 2001 Aug 16;31(3):339-40. Review.


Phosphorylation of RGS9-1 by an endogenous protein kinase in rod outer segments.

Hu G, Jang GF, Cowan CW, Wensel TG, Palczewski K.

J Biol Chem. 2001 Jun 22;276(25):22287-95. Epub 2001 Apr 5.


Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 A.

Slep KC, Kercher MA, He W, Cowan CW, Wensel TG, Sigler PB.

Nature. 2001 Feb 22;409(6823):1071-7.


RGS proteins: lessons from the RGS9 subfamily.

Cowan CW, He W, Wensel TG.

Prog Nucleic Acid Res Mol Biol. 2001;65:341-59. Review.


Multiple zinc binding sites in retinal rod cGMP phosphodiesterase, PDE6alpha beta.

He F, Seryshev AB, Cowan CW, Wensel TG.

J Biol Chem. 2000 Jul 7;275(27):20572-7.


Enzymology of GTPase acceleration in phototransduction.

Cowan CW, Wensel TG, Arshavsky VY.

Methods Enzymol. 2000;315:524-38. No abstract available.


Cloning and characterization of RGS9-2: a striatal-enriched alternatively spliced product of the RGS9 gene.

Rahman Z, Gold SJ, Potenza MN, Cowan CW, Ni YG, He W, Wensel TG, Nestler EJ.

J Neurosci. 1999 Mar 15;19(6):2016-26.


High expression levels in cones of RGS9, the predominant GTPase accelerating protein of rods.

Cowan CW, Fariss RN, Sokal I, Palczewski K, Wensel TG.

Proc Natl Acad Sci U S A. 1998 Apr 28;95(9):5351-6.


RGS9, a GTPase accelerator for phototransduction.

He W, Cowan CW, Wensel TG.

Neuron. 1998 Jan;20(1):95-102.


A comparison of the efficiency of G protein activation by ligand-free and light-activated forms of rhodopsin.

Melia TJ Jr, Cowan CW, Angleson JK, Wensel TG.

Biophys J. 1997 Dec;73(6):3182-91.

Supplemental Content

Loading ...
Support Center