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Items: 1 to 50 of 118

1.

Clinical and biological implications of target occupancy in CLL treated with the BTK inhibitor acalabrutinib.

Sun CCL, Nierman PK, Kendall EK, Cheung J, Gulrajani M, Herman SEM, Pleyer C, Ahn IE, Stetler-Stevenson M, Yuan C, Maric I, Gaglione EM, Harris HM, Pittaluga S, Wang MH, Patel P, Farooqui MZ, Izumi R, Hamdy A, Covey T, Wiestner A.

Blood. 2020 Mar 20. pii: blood.2019003715. doi: 10.1182/blood.2019003715. [Epub ahead of print]

PMID:
32202637
2.

Neurophysiological indices of the transfer of cognitive training gains to untrained tasks.

Wang X, Covey TJ.

Neurobiol Learn Mem. 2020 Mar 4;171:107205. doi: 10.1016/j.nlm.2020.107205. [Epub ahead of print]

PMID:
32145406
3.

Pharmacodynamic analysis of BTK inhibition in patients with chronic lymphocytic leukemia treated with acalabrutinib.

Alsadhan A, Cheung J, Gulrajani M, Gaglione EM, Nierman P, Hamdy A, Izumi R, Bibikova E, Patel P, Sun C, Covey T, Herman SEM, Wiestner A.

Clin Cancer Res. 2020 Feb 13. pii: clincanres.3505.2019. doi: 10.1158/1078-0432.CCR-19-3505. [Epub ahead of print]

PMID:
32054731
4.

Acalabrutinib monotherapy in patients with relapsed/refractory chronic lymphocytic leukemia: updated phase 2 results.

Byrd JC, Wierda WG, Schuh A, Devereux S, Chaves JM, Brown JR, Hillmen P, Martin P, Awan FT, Stephens DM, Ghia P, Barrientos J, Pagel JM, Woyach JA, Burke K, Covey T, Gulrajani M, Hamdy A, Izumi R, Frigault MM, Patel P, Rothbaum W, Wang MH, O'Brien S, Furman RR.

Blood. 2020 Apr 9;135(15):1204-1213. doi: 10.1182/blood.2018884940.

PMID:
31876911
5.

Design Characteristics to Eliminate the Need for Parameter Optimization in Nanoflow ESI-MS.

Kang Y, Schneider BB, Bedford L, Covey TR.

J Am Soc Mass Spectrom. 2019 Nov;30(11):2347-2357. doi: 10.1007/s13361-019-02301-8. Epub 2019 Aug 15.

PMID:
31418126
6.
7.

The Vouros Odyssey. Liquid chromatography/mass spectrometry from a chromatographic perspective and a Theseus Paradox.

Covey T.

Mass Spectrom Rev. 2020 Mar;39(1-2):15-34. doi: 10.1002/mas.21564. Epub 2018 Jul 19. Review.

PMID:
30024641
8.

Improved cognitive performance and event-related potential changes following working memory training in patients with multiple sclerosis.

Covey TJ, Shucard JL, Benedict RH, Weinstock-Guttman B, Shucard DW.

Mult Scler J Exp Transl Clin. 2018 Jan 11;4(1):2055217317747626. doi: 10.1177/2055217317747626. eCollection 2018 Jan-Mar.

9.

Acalabrutinib in relapsed or refractory mantle cell lymphoma (ACE-LY-004): a single-arm, multicentre, phase 2 trial.

Wang M, Rule S, Zinzani PL, Goy A, Casasnovas O, Smith SD, Damaj G, Doorduijn J, Lamy T, Morschhauser F, Panizo C, Shah B, Davies A, Eek R, Dupuis J, Jacobsen E, Kater AP, Le Gouill S, Oberic L, Robak T, Covey T, Dua R, Hamdy A, Huang X, Izumi R, Patel P, Rothbaum W, Slatter JG, Jurczak W.

Lancet. 2018 Feb 17;391(10121):659-667. doi: 10.1016/S0140-6736(17)33108-2. Epub 2017 Dec 11.

PMID:
29241979
10.

Fast quantitation of opioid isomers in human plasma by differential mobility spectrometry/mass spectrometry via SPME/open-port probe sampling interface.

Liu C, Gómez-Ríos GA, Schneider BB, Le Blanc JCY, Reyes-Garcés N, Arnold DW, Covey TR, Pawliszyn J.

Anal Chim Acta. 2017 Oct 23;991:89-94. doi: 10.1016/j.aca.2017.08.023. Epub 2017 Aug 28.

PMID:
29031302
11.

Acalabrutinib (ACP-196): A Covalent Bruton Tyrosine Kinase Inhibitor with a Differentiated Selectivity and In Vivo Potency Profile.

Barf T, Covey T, Izumi R, van de Kar B, Gulrajani M, van Lith B, van Hoek M, de Zwart E, Mittag D, Demont D, Verkaik S, Krantz F, Pearson PG, Ulrich R, Kaptein A.

J Pharmacol Exp Ther. 2017 Nov;363(2):240-252. doi: 10.1124/jpet.117.242909. Epub 2017 Sep 7.

PMID:
28882879
12.

On the Nature of Mass Spectrometer Analyzer Contamination.

Kang Y, Schneider BB, Covey TR.

J Am Soc Mass Spectrom. 2017 Nov;28(11):2384-2392. doi: 10.1007/s13361-017-1747-3. Epub 2017 Jul 21.

PMID:
28733968
13.

Maximizing Ion Transmission in Differential Mobility Spectrometry.

Schneider BB, Londry F, Nazarov EG, Kang Y, Covey TR.

J Am Soc Mass Spectrom. 2017 Oct;28(10):2151-2159. doi: 10.1007/s13361-017-1727-7. Epub 2017 Jun 29.

PMID:
28664477
14.

Combined BTK and PI3Kδ Inhibition with Acalabrutinib and ACP-319 Improves Survival and Tumor Control in CLL Mouse Model.

Niemann CU, Mora-Jensen HI, Dadashian EL, Krantz F, Covey T, Chen SS, Chiorazzi N, Izumi R, Ulrich R, Lannutti BJ, Wiestner A, Herman SEM.

Clin Cancer Res. 2017 Oct 1;23(19):5814-5823. doi: 10.1158/1078-0432.CCR-17-0650. Epub 2017 Jun 23.

15.

Event-related brain potential indices of cognitive function and brain resource reallocation during working memory in patients with Multiple Sclerosis.

Covey TJ, Shucard JL, Shucard DW.

Clin Neurophysiol. 2017 Apr;128(4):604-621. doi: 10.1016/j.clinph.2016.12.030. Epub 2017 Jan 29.

PMID:
28231478
16.

Open Port Probe Sampling Interface for the Direct Coupling of Biocompatible Solid-Phase Microextraction to Atmospheric Pressure Ionization Mass Spectrometry.

Gómez-Ríos GA, Liu C, Tascon M, Reyes-Garcés N, Arnold DW, Covey TR, Pawliszyn J.

Anal Chem. 2017 Apr 4;89(7):3805-3809. doi: 10.1021/acs.analchem.6b04737. Epub 2017 Feb 13.

PMID:
28192911
17.

The Bruton Tyrosine Kinase (BTK) Inhibitor Acalabrutinib Demonstrates Potent On-Target Effects and Efficacy in Two Mouse Models of Chronic Lymphocytic Leukemia.

Herman SEM, Montraveta A, Niemann CU, Mora-Jensen H, Gulrajani M, Krantz F, Mantel R, Smith LL, McClanahan F, Harrington BK, Colomer D, Covey T, Byrd JC, Izumi R, Kaptein A, Ulrich R, Johnson AJ, Lannutti BJ, Wiestner A, Woyach JA.

Clin Cancer Res. 2017 Jun 1;23(11):2831-2841. doi: 10.1158/1078-0432.CCR-16-0463. Epub 2016 Nov 30.

18.

Preclinical Evaluation of the Novel BTK Inhibitor Acalabrutinib in Canine Models of B-Cell Non-Hodgkin Lymphoma.

Harrington BK, Gardner HL, Izumi R, Hamdy A, Rothbaum W, Coombes KR, Covey T, Kaptein A, Gulrajani M, Van Lith B, Krejsa C, Coss CC, Russell DS, Zhang X, Urie BK, London CA, Byrd JC, Johnson AJ, Kisseberth WC.

PLoS One. 2016 Jul 19;11(7):e0159607. doi: 10.1371/journal.pone.0159607. eCollection 2016.

19.

Peter J. Todd (1949-2015).

Brenna T, Short T, Covey T, McLafferty F.

J Am Soc Mass Spectrom. 2016 Apr;27(4):563-4. doi: 10.1007/s13361-016-1335-y. No abstract available.

PMID:
26832346
20.

Acalabrutinib (ACP-196) in Relapsed Chronic Lymphocytic Leukemia.

Byrd JC, Harrington B, O'Brien S, Jones JA, Schuh A, Devereux S, Chaves J, Wierda WG, Awan FT, Brown JR, Hillmen P, Stephens DM, Ghia P, Barrientos JC, Pagel JM, Woyach J, Johnson D, Huang J, Wang X, Kaptein A, Lannutti BJ, Covey T, Fardis M, McGreivy J, Hamdy A, Rothbaum W, Izumi R, Diacovo TG, Johnson AJ, Furman RR.

N Engl J Med. 2016 Jan 28;374(4):323-32. doi: 10.1056/NEJMoa1509981. Epub 2015 Dec 7.

21.

Direct Interface between Digital Microfluidics and High Performance Liquid Chromatography-Mass Spectrometry.

Liu C, Choi K, Kang Y, Kim J, Fobel C, Seale B, Campbell JL, Covey TR, Wheeler AR.

Anal Chem. 2015 Dec 15;87(24):11967-72. doi: 10.1021/acs.analchem.5b03616. Epub 2015 Nov 23.

PMID:
26595766
22.

Differential mobility spectrometry/mass spectrometry history, theory, design optimization, simulations, and applications.

Schneider BB, Nazarov EG, Londry F, Vouros P, Covey TR.

Mass Spectrom Rev. 2016 Oct;35(6):687-737. doi: 10.1002/mas.21453. Epub 2015 May 11. Review.

PMID:
25962527
23.

Polymer micronozzle array for multiple electrosprays produced by templated synthesis and etching of microstructured fibers.

Fu Y, Gibson GT, Proulx A, Croteau A, Schneider BB, Covey TR, Oleschuk RD.

Anal Chem. 2015 Jan 6;87(1):747-53. doi: 10.1021/ac503664g. Epub 2014 Dec 18.

PMID:
25479072
24.

The role of the DNA damage response in zebrafish and cellular models of Diamond Blackfan anemia.

Danilova N, Bibikova E, Covey TM, Nathanson D, Dimitrova E, Konto Y, Lindgren A, Glader B, Radu CG, Sakamoto KM, Lin S.

Dis Model Mech. 2014 Jul;7(7):895-905. doi: 10.1242/dmm.015495. Epub 2014 May 8.

25.

The effects of exposure to traumatic stressors on inhibitory control in police officers: a dense electrode array study using a Go/NoGo continuous performance task.

Covey TJ, Shucard JL, Violanti JM, Lee J, Shucard DW.

Int J Psychophysiol. 2013 Mar;87(3):363-75. doi: 10.1016/j.ijpsycho.2013.03.009. Epub 2013 Mar 22.

PMID:
23528305
26.

Single cell network profiling assay in bladder cancer.

Covey TM, Vira MA, Westfall M, Gulrajani M, Cholankeril M, Okhunov Z, Levey HR, Marimpietri C, Hawtin R, Fields SZ, Cesano A.

Cytometry A. 2013 Apr;83(4):386-95. doi: 10.1002/cyto.a.22244. Epub 2013 Jan 8.

27.

A uniform human Wnt expression library reveals a shared secretory pathway and unique signaling activities.

Najdi R, Proffitt K, Sprowl S, Kaur S, Yu J, Covey TM, Virshup DM, Waterman ML.

Differentiation. 2012 Sep;84(2):203-13. doi: 10.1016/j.diff.2012.06.004. Epub 2012 Jul 9.

28.

PORCN moonlights in a Wnt-independent pathway that regulates cancer cell proliferation.

Covey TM, Kaur S, Tan Ong T, Proffitt KD, Wu Y, Tan P, Virshup DM.

PLoS One. 2012;7(4):e34532. doi: 10.1371/journal.pone.0034532. Epub 2012 Apr 11.

29.

Comparison of neuropsychological impairment and vocational outcomes in systemic lupus erythematosus and multiple sclerosis patients.

Covey TJ, Shucard JL, Shucard DW, Stegen S, Benedict RH.

J Int Neuropsychol Soc. 2012 May;18(3):530-40. doi: 10.1017/S1355617712000057. Epub 2012 Mar 13.

PMID:
22410107
30.

Additional thoughts on corporate influence in veterinary education.

Covey T.

J Am Vet Med Assoc. 2011 Dec 15;239(12):1544. doi: 10.2460/javma.239.12.1544. No abstract available.

PMID:
22129115
31.

Information processing speed, neural efficiency, and working memory performance in multiple sclerosis: differential relationships with structural magnetic resonance imaging.

Covey TJ, Zivadinov R, Shucard JL, Shucard DW.

J Clin Exp Neuropsychol. 2011 Dec;33(10):1129-45. doi: 10.1080/13803395.2011.614597. Epub 2011 Nov 3.

PMID:
22047454
32.

Rapid analysis of isomeric exogenous metabolites by differential mobility spectrometry-mass spectrometry.

Parson WB, Schneider BB, Kertesz V, Corr JJ, Covey TR, Van Berkel GJ.

Rapid Commun Mass Spectrom. 2011 Nov 30;25(22):3382-6. doi: 10.1002/rcm.5238.

PMID:
22002690
33.

Differential mobility spectrometry of isomeric protonated dipeptides: modifier and field effects on ion mobility and stability.

Blagojevic V, Chramow A, Schneider BB, Covey TR, Bohme DK.

Anal Chem. 2011 May 1;83(9):3470-6. doi: 10.1021/ac200100s. Epub 2011 Apr 19.

PMID:
21504141
34.

Planar differential mobility spectrometer as a pre-filter for atmospheric pressure ionization mass spectrometry.

Schneider BB, Covey TR, Coy SL, Krylov EV, Nazarov EG.

Int J Mass Spectrom. 2010 Dec 1;298(1-3):45-54.

35.

Signaling changes in the stem cell factor-AKT-S6 pathway in diagnostic AML samples are associated with disease relapse.

Kornblau SM, Covey T, Putta S, Cohen A, Woronicz J, Fantl WJ, Gayko U, Cesano A.

Blood Cancer J. 2011 Feb;1(2):e3. doi: 10.1038/bcj.2010.2. Epub 2011 Feb 11. No abstract available.

36.

Modulated multiparametric phosphoflow cytometry in hematological malignancies: technology and clinical applications.

Covey TM, Cesano A.

Best Pract Res Clin Haematol. 2010 Sep;23(3):319-31. doi: 10.1016/j.beha.2010.07.002. Epub 2010 Nov 10. Review.

PMID:
21112033
37.

Alkylation of the tumor suppressor PTEN activates Akt and β-catenin signaling: a mechanism linking inflammation and oxidative stress with cancer.

Covey TM, Edes K, Coombs GS, Virshup DM, Fitzpatrick FA.

PLoS One. 2010 Oct 21;5(10):e13545. doi: 10.1371/journal.pone.0013545.

38.

WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification.

Coombs GS, Yu J, Canning CA, Veltri CA, Covey TM, Cheong JK, Utomo V, Banerjee N, Zhang ZH, Jadulco RC, Concepcion GP, Bugni TS, Harper MK, Mihalek I, Jones CM, Ireland CM, Virshup DM.

J Cell Sci. 2010 Oct 1;123(Pt 19):3357-67. doi: 10.1242/jcs.072132. Epub 2010 Sep 7.

39.

Distinct patterns of DNA damage response and apoptosis correlate with Jak/Stat and PI3kinase response profiles in human acute myelogenous leukemia.

Rosen DB, Putta S, Covey T, Huang YW, Nolan GP, Cesano A, Minden MD, Fantl WJ.

PLoS One. 2010 Aug 25;5(8):e12405. doi: 10.1371/journal.pone.0012405.

40.

UV-induced bond modifications in thymine and thymine dideoxynucleotide: structural elucidation of isomers by differential mobility mass spectrometry.

St-Jacques A, Anichina J, Schneider BB, Covey TR, Bohme DK.

Anal Chem. 2010 Jul 15;82(14):6163-7. doi: 10.1021/ac100977b.

PMID:
20578686
41.

Dynamic single-cell network profiles in acute myelogenous leukemia are associated with patient response to standard induction therapy.

Kornblau SM, Minden MD, Rosen DB, Putta S, Cohen A, Covey T, Spellmeyer DC, Fantl WJ, Gayko U, Cesano A.

Clin Cancer Res. 2010 Jul 15;16(14):3721-33. doi: 10.1158/1078-0432.CCR-10-0093. Epub 2010 Jun 4.

42.

Single-cell network profiling (SCNP) by flow cytometry in autoimmune disease.

Covey TM, Cesano A, Parkinson DR.

Autoimmunity. 2010 Nov;43(7):550-9. doi: 10.3109/08916931003674774. Review.

PMID:
20482423
43.

Detection of Radiation-Exposure Biomarkers by Differential Mobility Prefiltered Mass Spectrometry (DMS-MS).

Coy SL, Krylov EV, Schneider BB, Covey TR, Brenner DJ, Tyburski JB, Patterson AD, Krausz KW, Fornace AJ, Nazarov EG.

Int J Mass Spectrom. 2010 Apr 15;291(3):108-117.

44.

Selection and generation of waveforms for differential mobility spectrometry.

Krylov EV, Coy SL, Vandermey J, Schneider BB, Covey TR, Nazarov EG.

Rev Sci Instrum. 2010 Feb;81(2):024101. doi: 10.1063/1.3284507.

45.

Single cell network profiling (SCNP): mapping drug and target interactions.

Covey TM, Putta S, Cesano A.

Assay Drug Dev Technol. 2010 Jun;8(3):321-43. doi: 10.1089/adt.2009.0251.

PMID:
20158439
46.

Chemical effects in the separation process of a differential mobility/mass spectrometer system.

Schneider BB, Covey TR, Coy SL, Krylov EV, Nazarov EG.

Anal Chem. 2010 Mar 1;82(5):1867-80. doi: 10.1021/ac902571u.

47.

A tribute to the scientific career of Dr Andries Bruins.

Covey TR.

Eur J Mass Spectrom (Chichester). 2010;16(1):1-10. doi: 10.1255/ejms.1053. No abstract available.

PMID:
20065520
48.

Control of chemical effects in the separation process of a differential mobility mass spectrometer system.

Schneider BB, Covey TR, Coy SL, Krylov EV, Nazarov EG.

Eur J Mass Spectrom (Chichester). 2010;16(1):57-71. doi: 10.1255/ejms.1025.

49.

Atmospheric pressure ion sources.

Covey TR, Thomson BA, Schneider BB.

Mass Spectrom Rev. 2009 Nov-Dec;28(6):870-97. doi: 10.1002/mas.20246.

PMID:
19626583
50.

Alternative reagents for chemical noise reduction in liquid chromatography-mass spectrometry using selective ion-molecule reactions.

Guo X, Bruins AP, Covey TR, Trötzmüller M, Lankmayr E.

J Am Soc Mass Spectrom. 2009 Jan;20(1):105-11. doi: 10.1016/j.jasms.2008.09.021. Epub 2008 Sep 30.

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