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Items: 1 to 50 of 199

1.

In Situ Molecular Architecture of the Helicobacter pylori Cag Type IV Secretion System.

Hu B, Khara P, Song L, Lin AS, Frick-Cheng AE, Harvey ML, Cover TL, Christie PJ.

MBio. 2019 May 14;10(3). pii: e00849-19. doi: 10.1128/mBio.00849-19.

2.

Effect of environmental salt concentration on the Helicobacter pylori exoproteome.

Caston RR, Loh JT, Voss BJ, McDonald WH, Scholz MB, McClain MS, Cover TL.

J Proteomics. 2019 Jun 30;202:103374. doi: 10.1016/j.jprot.2019.05.002. Epub 2019 May 4.

PMID:
31063819
3.

Cryo-EM Analysis Reveals Structural Basis of Helicobacter pylori VacA Toxin Oligomerization.

Su M, Erwin AL, Campbell AM, Pyburn TM, Salay LE, Hanks JL, Lacy DB, Akey DL, Cover TL, Ohi MD.

J Mol Biol. 2019 May 3;431(10):1956-1965. doi: 10.1016/j.jmb.2019.03.029. Epub 2019 Apr 5.

PMID:
30954575
4.

Helicobacter pylori VacA Targets Myeloid Cells in the Gastric Lamina Propria To Promote Peripherally Induced Regulatory T-Cell Differentiation and Persistent Infection.

Altobelli A, Bauer M, Velez K, Cover TL, Müller A.

MBio. 2019 Mar 19;10(2). pii: e00261-19. doi: 10.1128/mBio.00261-19.

5.

Intracellular Degradation of Helicobacter pylori VacA Toxin as a Determinant of Gastric Epithelial Cell Viability.

Foegeding NJ, Raghunathan K, Campbell AM, Kim SW, Lau KS, Kenworthy AK, Cover TL, Ohi MD.

Infect Immun. 2019 Mar 25;87(4). pii: e00783-18. doi: 10.1128/IAI.00783-18. Print 2019 Apr.

PMID:
30692181
6.

Role of a Stem-Loop Structure in Helicobacter pylori cagA Transcript Stability.

Loh JT, Lin AS, Beckett AC, McClain MS, Cover TL.

Infect Immun. 2019 Jan 24;87(2). pii: e00692-18. doi: 10.1128/IAI.00692-18. Print 2019 Feb.

PMID:
30510104
7.

Carcinogenic Helicobacter pylori Strains Selectively Dysregulate the In Vivo Gastric Proteome, Which May Be Associated with Stomach Cancer Progression.

Noto JM, Rose KL, Hachey AJ, Delgado AG, Romero-Gallo J, Wroblewski LE, Schneider BG, Shah SC, Cover TL, Wilson KT, Israel DA, Roa JC, Schey KL, Zavros Y, Piazuelo MB, Peek RM Jr.

Mol Cell Proteomics. 2019 Feb;18(2):352-371. doi: 10.1074/mcp.RA118.001181. Epub 2018 Nov 19.

PMID:
30455363
8.

Serologic Response to Helicobacter pylori Proteins Associated With Risk of Colorectal Cancer Among Diverse Populations in the United States.

Butt J, Varga MG, Blot WJ, Teras L, Visvanathan K, Le Marchand L, Haiman C, Chen Y, Bao Y, Sesso HD, Wassertheil-Smoller S, Ho GYF, Tinker LE, Peek RM, Potter JD, Cover TL, Hendrix LH, Huang LC, Hyslop T, Um C, Grodstein F, Song M, Zeleniuch-Jacquotte A, Berndt S, Hildesheim A, Waterboer T, Pawlita M, Epplein M.

Gastroenterology. 2019 Jan;156(1):175-186.e2. doi: 10.1053/j.gastro.2018.09.054. Epub 2018 Oct 6.

PMID:
30296434
9.

Transmaternal Helicobacter pylori exposure reduces allergic airway inflammation in offspring through regulatory T cells.

Kyburz A, Fallegger A, Zhang X, Altobelli A, Artola-Boran M, Borbet T, Urban S, Paul P, Münz C, Floess S, Huehn J, Cover TL, Blaser MJ, Taube C, Müller A.

J Allergy Clin Immunol. 2019 Apr;143(4):1496-1512.e11. doi: 10.1016/j.jaci.2018.07.046. Epub 2018 Sep 19.

PMID:
30240703
10.

Antibody Responses to Streptococcus Gallolyticus Subspecies Gallolyticus Proteins in a Large Prospective Colorectal Cancer Cohort Consortium.

Butt J, Blot WJ, Teras LR, Visvanathan K, Le Marchand L, Haiman CA, Chen Y, Bao Y, Sesso HD, Wassertheil-Smoller S, Ho GY, Tinker LF, Peek RM, Potter JD, Cover TL, Hendrix LH, Huang LC, Waterboer T, Pawlita M, Epplein M.

Cancer Epidemiol Biomarkers Prev. 2018 Oct;27(10):1186-1194. doi: 10.1158/1055-9965.EPI-18-0249. Epub 2018 Jul 23.

PMID:
30038049
11.

Helicobacter pylori genetic diversification in the Mongolian gerbil model.

Beckett AC, Loh JT, Chopra A, Leary S, Lin AS, McDonnell WJ, Dixon BREA, Noto JM, Israel DA, Peek RM Jr, Mallal S, Algood HMS, Cover TL.

PeerJ. 2018 May 18;6:e4803. doi: 10.7717/peerj.4803. eCollection 2018.

12.

Determinants of Raft Partitioning of the Helicobacter pylori Pore-Forming Toxin VacA.

Raghunathan K, Foegeding NJ, Campbell AM, Cover TL, Ohi MD, Kenworthy AK.

Infect Immun. 2018 Apr 23;86(5). pii: e00872-17. doi: 10.1128/IAI.00872-17. Print 2018 May.

13.

High-Salt Conditions Alter Transcription of Helicobacter pylori Genes Encoding Outer Membrane Proteins.

Loh JT, Beckett AC, Scholz MB, Cover TL.

Infect Immun. 2018 Feb 20;86(3). pii: e00626-17. doi: 10.1128/IAI.00626-17. Print 2018 Mar.

14.

Genetic signatures for Helicobacter pylori strains of West African origin.

Bullock KK, Shaffer CL, Brooks AW, Secka O, Forsyth MH, McClain MS, Cover TL.

PLoS One. 2017 Nov 29;12(11):e0188804. doi: 10.1371/journal.pone.0188804. eCollection 2017.

15.

Helicobacter pylori Vacuolating Toxin and Gastric Cancer.

McClain MS, Beckett AC, Cover TL.

Toxins (Basel). 2017 Oct 12;9(10). pii: E316. doi: 10.3390/toxins9100316. Review.

16.

Pan-genomic analyses identify key Helicobacter pylori pathogenic loci modified by carcinogenic host microenvironments.

Noto JM, Chopra A, Loh JT, Romero-Gallo J, Piazuelo MB, Watson M, Leary S, Beckett AC, Wilson KT, Cover TL, Mallal S, Israel DA, Peek RM.

Gut. 2018 Oct;67(10):1793-1804. doi: 10.1136/gutjnl-2017-313863. Epub 2017 Sep 18.

17.

Helicobacter pylori and its secreted immunomodulator VacA protect against anaphylaxis in experimental models of food allergy.

Kyburz A, Urban S, Altobelli A, Floess S, Huehn J, Cover TL, Müller A.

Clin Exp Allergy. 2017 Oct;47(10):1331-1341. doi: 10.1111/cea.12996. Epub 2017 Sep 11.

18.

Oxidative Phosphorylation System in Gastric Carcinomas and Gastritis.

Feichtinger RG, Neureiter D, Skaria T, Wessler S, Cover TL, Mayr JA, Zimmermann FA, Posselt G, Sperl W, Kofler B.

Oxid Med Cell Longev. 2017;2017:1320241. doi: 10.1155/2017/1320241. Epub 2017 Jun 28.

19.

Magnetic Extraction of Acinetobacter baumannii Using Colistin-Functionalized γ-Fe2O3/Au Core/Shell Composite Nanoclusters.

Bell CS, Mejías R, Miller SE, Greer JM, McClain MS, Cover TL, Giorgio TD.

ACS Appl Mater Interfaces. 2017 Aug 16;9(32):26719-26730. doi: 10.1021/acsami.7b07304. Epub 2017 Aug 4.

PMID:
28696672
20.

Epithelial Coculture and l-Lactate Promote Growth of Helicobacter cinaedi under H2-Free Aerobic Conditions.

Schmitz JE, Taniguchi T, Misawa N, Cover TL.

Appl Environ Microbiol. 2016 Oct 27;82(22):6701-6714. Print 2016 Nov 15.

21.

Dynamic Computational Model of Symptomatic Bacteremia to Inform Bacterial Separation Treatment Requirements.

Miller SE, Bell CS, McClain MS, Cover TL, Giorgio TD.

PLoS One. 2016 Sep 22;11(9):e0163167. doi: 10.1371/journal.pone.0163167. eCollection 2016.

22.

Dietary Composition Influences Incidence of Helicobacter pylori-Induced Iron Deficiency Anemia and Gastric Ulceration.

Beckett AC, Piazuelo MB, Noto JM, Peek RM Jr, Washington MK, Algood HM, Cover TL.

Infect Immun. 2016 Nov 18;84(12):3338-3349. Print 2016 Dec.

23.

Colistin-Functionalized Nanoparticles for the Rapid Capture of Acinetobacter baumannii.

Miller SE, Bell CS, Mejias R, McClain MS, Cover TL, Giorgio TD.

J Biomed Nanotechnol. 2016 Sep;12(9):1806-19.

PMID:
29345892
24.

A Nonoligomerizing Mutant Form of Helicobacter pylori VacA Allows Structural Analysis of the p33 Domain.

González-Rivera C, Campbell AM, Rutherford SA, Pyburn TM, Foegeding NJ, Barke TL, Spiller BW, McClain MS, Ohi MD, Lacy DB, Cover TL.

Infect Immun. 2016 Aug 19;84(9):2662-70. doi: 10.1128/IAI.00254-16. Print 2016 Sep.

25.

Structural organization of membrane-inserted hexamers formed by Helicobacter pylori VacA toxin.

Pyburn TM, Foegeding NJ, González-Rivera C, McDonald NA, Gould KL, Cover TL, Ohi MD.

Mol Microbiol. 2016 Oct;102(1):22-36. doi: 10.1111/mmi.13443. Epub 2016 Jul 8.

26.

An Overview of Helicobacter pylori VacA Toxin Biology.

Foegeding NJ, Caston RR, McClain MS, Ohi MD, Cover TL.

Toxins (Basel). 2016 Jun 3;8(6). pii: E173. doi: 10.3390/toxins8060173. Review.

27.

Peptidomimetic Small Molecules Disrupt Type IV Secretion System Activity in Diverse Bacterial Pathogens.

Shaffer CL, Good JA, Kumar S, Krishnan KS, Gaddy JA, Loh JT, Chappell J, Almqvist F, Cover TL, Hadjifrangiskou M.

MBio. 2016 Apr 26;7(2):e00221-16. doi: 10.1128/mBio.00221-16.

28.

Supporting data for analysis of the Helicobacter pylori exoproteome.

Snider CA, Voss BJ, McDonald WH, Cover TL.

Data Brief. 2015 Oct 17;5:560-3. doi: 10.1016/j.dib.2015.10.008. eCollection 2015 Dec.

29.

Helicobacter pylori Diversity and Gastric Cancer Risk.

Cover TL.

MBio. 2016 Jan 26;7(1):e01869-15. doi: 10.1128/mBio.01869-15. Review.

30.

Molecular and Structural Analysis of the Helicobacter pylori cag Type IV Secretion System Core Complex.

Frick-Cheng AE, Pyburn TM, Voss BJ, McDonald WH, Ohi MD, Cover TL.

MBio. 2016 Jan 12;7(1):e02001-15. doi: 10.1128/mBio.02001-15.

31.
32.

Helicobacter pylori adaptation in vivo in response to a high-salt diet.

Loh JT, Gaddy JA, Algood HM, Gaudieri S, Mallal S, Cover TL.

Infect Immun. 2015 Dec;83(12):4871-83. doi: 10.1128/IAI.00918-15. Epub 2015 Oct 5.

33.

Growth phase-dependent composition of the Helicobacter pylori exoproteome.

Snider CA, Voss BJ, McDonald WH, Cover TL.

J Proteomics. 2016 Jan 1;130:94-107. doi: 10.1016/j.jprot.2015.08.025. Epub 2015 Sep 9.

34.

Alteration of the Helicobacter pylori membrane proteome in response to changes in environmental salt concentration.

Voss BJ, Loh JT, Hill S, Rose KL, McDonald WH, Cover TL.

Proteomics Clin Appl. 2015 Dec;9(11-12):1021-34. doi: 10.1002/prca.201400176. Epub 2015 Sep 14.

35.

Regulation of Helicobacter pylori Virulence Within the Context of Iron Deficiency.

Noto JM, Lee JY, Gaddy JA, Cover TL, Amieva MR, Peek RM Jr.

J Infect Dis. 2015 Jun 1;211(11):1790-4. doi: 10.1093/infdis/jiu805. Epub 2014 Dec 11.

36.

The host protein calprotectin modulates the Helicobacter pylori cag type IV secretion system via zinc sequestration.

Gaddy JA, Radin JN, Loh JT, Piazuelo MB, Kehl-Fie TE, Delgado AG, Ilca FT, Peek RM, Cover TL, Chazin WJ, Skaar EP, Scott Algood HM.

PLoS Pathog. 2014 Oct 16;10(10):e1004450. doi: 10.1371/journal.ppat.1004450. eCollection 2014 Oct.

37.

Effective treatment of allergic airway inflammation with Helicobacter pylori immunomodulators requires BATF3-dependent dendritic cells and IL-10.

Engler DB, Reuter S, van Wijck Y, Urban S, Kyburz A, Maxeiner J, Martin H, Yogev N, Waisman A, Gerhard M, Cover TL, Taube C, Müller A.

Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):11810-5. doi: 10.1073/pnas.1410579111. Epub 2014 Jul 29.

38.

Genes required for assembly of pili associated with the Helicobacter pylori cag type IV secretion system.

Johnson EM, Gaddy JA, Voss BJ, Hennig EE, Cover TL.

Infect Immun. 2014 Aug;82(8):3457-70. doi: 10.1128/IAI.01640-14. Epub 2014 Jun 2.

39.

Analysis of surface-exposed outer membrane proteins in Helicobacter pylori.

Voss BJ, Gaddy JA, McDonald WH, Cover TL.

J Bacteriol. 2014 Jul;196(13):2455-71. doi: 10.1128/JB.01768-14. Epub 2014 Apr 25.

40.

Human and Helicobacter pylori coevolution shapes the risk of gastric disease.

Kodaman N, Pazos A, Schneider BG, Piazuelo MB, Mera R, Sobota RS, Sicinschi LA, Shaffer CL, Romero-Gallo J, de Sablet T, Harder RH, Bravo LE, Peek RM Jr, Wilson KT, Cover TL, Williams SM, Correa P.

Proc Natl Acad Sci U S A. 2014 Jan 28;111(4):1455-60. doi: 10.1073/pnas.1318093111. Epub 2014 Jan 13.

41.

Role of connexin 43 in Helicobacter pylori VacA-induced cell death.

Radin JN, González-Rivera C, Frick-Cheng AE, Sheng J, Gaddy JA, Rubin DH, Algood HM, McClain MS, Cover TL.

Infect Immun. 2014 Jan;82(1):423-32. doi: 10.1128/IAI.00827-13. Epub 2013 Nov 4.

42.

Control of gene expression in Helicobacter pylori using the Tet repressor.

McClain MS, Duncan SS, Gaddy JA, Cover TL.

J Microbiol Methods. 2013 Dec;95(3):336-41. doi: 10.1016/j.mimet.2013.09.019. Epub 2013 Oct 8.

43.

Genome Sequences of Three hpAfrica2 Strains of Helicobacter pylori.

Duncan SS, Bertoli MT, Kersulyte D, Valk PL, Tamma S, Segal I, McClain MS, Cover TL, Berg DE.

Genome Announc. 2013 Sep 26;1(5). pii: e00729-13. doi: 10.1128/genomeA.00729-13.

44.

Diet, microbial virulence, and Helicobacter pylori-induced gastric cancer.

Cover TL, Peek RM Jr.

Gut Microbes. 2013 Nov-Dec;4(6):482-93. doi: 10.4161/gmic.26262. Epub 2013 Sep 3. Review.

45.

Impaired autophagy, defective T cell homeostasis, and a wasting syndrome in mice with a T cell-specific deletion of Vps34.

Parekh VV, Wu L, Boyd KL, Williams JA, Gaddy JA, Olivares-Villagómez D, Cover TL, Zong WX, Zhang J, Van Kaer L.

J Immunol. 2013 May 15;190(10):5086-101. doi: 10.4049/jimmunol.1202071. Epub 2013 Apr 17.

46.

Flagellar localization of a Helicobacter pylori autotransporter protein.

Radin JN, Gaddy JA, González-Rivera C, Loh JT, Algood HM, Cover TL.

MBio. 2013 Apr 9;4(2):e00613-12. doi: 10.1128/mBio.00613-12.

47.

High dietary salt intake exacerbates Helicobacter pylori-induced gastric carcinogenesis.

Gaddy JA, Radin JN, Loh JT, Zhang F, Washington MK, Peek RM Jr, Algood HM, Cover TL.

Infect Immun. 2013 Jun;81(6):2258-67. doi: 10.1128/IAI.01271-12. Epub 2013 Apr 8.

48.

Functional plasticity in the type IV secretion system of Helicobacter pylori.

Barrozo RM, Cooke CL, Hansen LM, Lam AM, Gaddy JA, Johnson EM, Cariaga TA, Suarez G, Peek RM Jr, Cover TL, Solnick JV.

PLoS Pathog. 2013 Feb;9(2):e1003189. doi: 10.1371/journal.ppat.1003189. Epub 2013 Feb 28.

49.

Comparative genomic analysis of East Asian and non-Asian Helicobacter pylori strains identifies rapidly evolving genes.

Duncan SS, Valk PL, McClain MS, Shaffer CL, Metcalf JA, Bordenstein SR, Cover TL.

PLoS One. 2013;8(1):e55120. doi: 10.1371/journal.pone.0055120. Epub 2013 Jan 31.

50.

Downregulated Th17 responses are associated with reduced gastritis in Helicobacter pylori-infected children.

Serrano C, Wright SW, Bimczok D, Shaffer CL, Cover TL, Venegas A, Salazar MG, Smythies LE, Harris PR, Smith PD.

Mucosal Immunol. 2013 Sep;6(5):950-959. doi: 10.1038/mi.2012.133. Epub 2013 Jan 9.

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