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Items: 1 to 50 of 247

1.

ZIKA VIRUS SEROPREVALENCE IN BLOOD DONORS FROM THE NORTHEASTERN REGION OF SÃO PAULO STATE, BRAZIL, BETWEEN 2015 - 2017.

Slavov SN, Guaragna Machado RR, Ferreira AR, Soares CP, Araujo DB, Leal Oliveira DB, Covas DT, Durigon EL, Kashima S.

J Infect. 2019 Nov 15. pii: S0163-4453(19)30296-8. doi: 10.1016/j.jinf.2019.10.002. [Epub ahead of print]

PMID:
31738944
2.

CAR-T Cells for Cancer Treatment: Current Design and Next Frontiers.

Picanço-Castro V, Swiech K, Malmegrim KCR, Covas DT.

Methods Mol Biol. 2020;2086:1-10. doi: 10.1007/978-1-0716-0146-4_1.

PMID:
31707664
3.

Establishment of a simple and efficient platform for car-t cell generation and expansion: from lentiviral production to in vivo studies.

Picanço-Castro V, Moço PD, Mizukami A, Vaz LD, de Souza Fernandes Pereira M, Silvestre RN, de Azevedo JTC, de Sousa Bomfim A, de Abreu Neto MS, Malmegrim KCR, Swiech K, Covas DT.

Hematol Transfus Cell Ther. 2019 Oct 9. pii: S2531-1379(19)30135-X. doi: 10.1016/j.htct.2019.06.007. [Epub ahead of print]

4.

Serological evidence of Borrelia circulation among blood donors in the São Paulo state, Brazil.

Slavov SN, Christova IS, Ferreira AR, Rodrigues ES, Bianquini ML, Hespanhol MR, Covas DT, Kashima S.

Transfus Med. 2019 Oct;29(5):358-363. doi: 10.1111/tme.12627. Epub 2019 Aug 30.

PMID:
31468639
5.

Simultaneous zika and dengue serotype-4 viral detection and isolation from a donor plasma unit.

Slavov SN, Ferreira FU, Rodrigues ES, Gomes R, Covas DT, Kashima S.

J Vector Borne Dis. 2019 Apr-Jun;56(2):166-169. doi: 10.4103/0972-9062.263724.

6.

Proteomic Identification and Time-Course Monitoring of Secreted Proteins During Expansion of Human Mesenchymal Stem/Stromal in Stirred-Tank Bioreactor.

Mizukami A, Thomé CH, Ferreira GA, Lanfredi GP, Covas DT, Pitteri SJ, Swiech K, Faça VM.

Front Bioeng Biotechnol. 2019 Jun 26;7:154. doi: 10.3389/fbioe.2019.00154. eCollection 2019.

7.

High-content screen in human pluripotent cells identifies miRNA-regulated pathways controlling pluripotency and differentiation.

de Souza Lima IM, Schiavinato JLDS, Paulino Leite SB, Sastre D, Bezerra HLO, Sangiorgi B, Corveloni AC, Thomé CH, Faça VM, Covas DT, Zago MA, Giacca M, Mano M, Panepucci RA.

Stem Cell Res Ther. 2019 Jul 8;10(1):202. doi: 10.1186/s13287-019-1318-6.

8.

Human pegivirus-1 (HPgV-1) RNA prevalence and genotypes in volunteer blood donors from the Brazilian Amazon.

Slavov SN, Maraninchi Silveira R, Hespanhol MR, Sauvage V, Rodrigues ES, Fontanari Krause L, Bittencourt HT, Caro V, Laperche S, Covas DT, Kashima S.

Transfus Clin Biol. 2019 Jun 18. pii: S1246-7820(19)30070-9. doi: 10.1016/j.tracli.2019.06.005. [Epub ahead of print]

PMID:
31277987
9.

Correction to: Priming approaches to improve the efficacy of mesenchymal stromal cell-based therapies.

Noronha NC, Mizukami A, Caliári-Oliveira C, Cominal JG, Rocha JLM, Covas DT, Swiech K, Malmegrim KCR.

Stem Cell Res Ther. 2019 May 17;10(1):132. doi: 10.1186/s13287-019-1259-0.

10.

Titanium with nanotopography induces osteoblast differentiation through regulation of integrin αV.

Lopes HB, Freitas GP, Fantacini DMC, Picanço-Castro V, Covas DT, Rosa AL, Beloti MM.

J Cell Biochem. 2019 Oct;120(10):16723-16732. doi: 10.1002/jcb.28930. Epub 2019 May 15.

PMID:
31090958
11.

Prevalence of hepatitis E virus infection in multiple transfused Brazilian patients with thalassemia and sickle cell disease.

Slavov SN, Maçonetto JDM, Martinez EZ, Silva-Pinto AC, Covas DT, Eis-Hübinger AM, Kashima S.

J Med Virol. 2019 Sep;91(9):1693-1697. doi: 10.1002/jmv.25498. Epub 2019 May 22.

PMID:
31066064
12.

Priming approaches to improve the efficacy of mesenchymal stromal cell-based therapies.

Noronha NC, Mizukami A, Caliári-Oliveira C, Cominal JG, Rocha JLM, Covas DT, Swiech K, Malmegrim KCR.

Stem Cell Res Ther. 2019 May 2;10(1):131. doi: 10.1186/s13287-019-1224-y. Review. Erratum in: Stem Cell Res Ther. 2019 May 17;10(1):132.

13.

Autologous adipose-derived stem cell for painful leg ulcers in patients with sickle cell disease. A preliminary study.

Farina Junior JA, De Santis GC, Orellana MD, Silva-Pinto AC, de Oliveira Guirro EC, de Carvalho CS, Zampar AG, Coltro PS, Tirapeli LF, Covas DT.

Br J Haematol. 2019 Aug;186(3):e47-e50. doi: 10.1111/bjh.15891. Epub 2019 Mar 28. No abstract available.

PMID:
30919931
14.

Generation of integration-free induced pluripotent stem cells from blood-derived cells isolated from patient with severe haemophilia A.

Ferreira AF, Ferreira FU, Costa PNMD, Catelli LF, Favarin Macedo MDC, Santos TPMD, Leopoldino AM, Picanço-Castro V, Kashima S, Covas DT.

Haemophilia. 2019 May;25(3):e195-e199. doi: 10.1111/hae.13716. Epub 2019 Mar 13. No abstract available.

PMID:
30866120
15.

Parvovirus B19 seroprevalence, viral load, and genotype characterization in volunteer blood donors from southern Brazil.

Slavov SN, Rodrigues ES, Sauvage V, Caro V, Diefenbach CF, Zimmermann AM, Covas DT, Laperche S, Kashima S.

J Med Virol. 2019 Jul;91(7):1224-1231. doi: 10.1002/jmv.25453. Epub 2019 Mar 25.

PMID:
30851123
16.

Triple-modal imaging of stem-cells labeled with multimodal nanoparticles, applied in a stroke model.

da Silva HR, Mamani JB, Nucci MP, Nucci LP, Kondo AT, Fantacini DMC, de Souza LEB, Picanço-Castro V, Covas DT, Kutner JM, de Oliveira FA, Hamerschlak N, Gamarra LF.

World J Stem Cells. 2019 Feb 26;11(2):100-123. doi: 10.4252/wjsc.v11.i2.100.

17.

Mobilizing hematopoietic progenitor cells in donors with sickle cell trait is safe.

De Santis GC, Prado BPA Jr, Dotoli GM, Simões BP, Covas DT.

Hematol Transfus Cell Ther. 2019 Jan-Mar;41(1):101-102. doi: 10.1016/j.htct.2018.04.003. Epub 2018 May 25. No abstract available.

18.

"Molecular analysis of the rare S-s- red blood cell phenotype in blood donors and patients in south-east Brazil".

Santos FLS, Cuter TB, Rodrigues ES, Bettarello ÊC, Ubiali EMA, Castilho LM, Kashima S, Covas DT.

Vox Sang. 2019 Apr;114(3):262-267. doi: 10.1111/vox.12751. Epub 2019 Feb 19.

PMID:
30784083
19.

Human pegivirus-1 (HPgV-1, GBV-C) RNA prevalence and genotype diversity among volunteer blood donors from an intra-hospital hemotherapy service in Southern Brazil.

Slavov SN, Silveira RM, Rodrigues ES, Diefenbach CF, Zimmermann AM, Covas DT, Kashima S.

Transfus Apher Sci. 2019 Apr;58(2):174-178. doi: 10.1016/j.transci.2019.01.002. Epub 2019 Jan 25.

PMID:
30709590
20.

DPP-4 Inhibition Leads to Decreased Pancreatic Inflammatory Profile and Increased Frequency of Regulatory T Cells in Experimental Type 1 Diabetes.

Davanso MR, Caliari-Oliveira C, Couri CEB, Covas DT, de Oliveira Leal AM, Voltarelli JC, Malmegrim KCR, Yaochite JNU.

Inflammation. 2019 Apr;42(2):449-462. doi: 10.1007/s10753-018-00954-3.

PMID:
30707388
21.

Endothelial cells from different anatomical origin have distinct responses during SNAIL/TGF-β2-mediated endothelial-mesenchymal transition.

Pinto MT, Ferreira Melo FU, Malta TM, Rodrigues ES, Plaça JR, Silva WA Jr, Panepucci RA, Covas DT, de Oliveira Rodrigues C, Kashima S.

Am J Transl Res. 2018 Dec 15;10(12):4065-4081. eCollection 2018.

22.

Guidelines on transfusion of red blood cells: Prognosis of patients who decline blood transfusions.

Langhi DM, Covas DT, Marques JFC, Mendrone A, Ubiali EMA, Santis GC, Kelmann G, Bernardo WM.

Hematol Transfus Cell Ther. 2018 Oct-Dec;40(4):377-381. doi: 10.1016/j.htct.2018.08.001. Epub 2018 Sep 25. No abstract available.

23.

Seroprevalence of Chikungunya virus in blood donors from Northern and Southeastern Brazil.

Slavov SN, Otaguiri KK, Bianquini ML, Bitencourt HTO, Chagas MCM, Guerreiro DSS, Figueiredo LTM, Covas DT, Kashima S.

Hematol Transfus Cell Ther. 2018 Oct-Dec;40(4):358-362. doi: 10.1016/j.htct.2018.04.002. Epub 2018 May 25.

24.

Short Communication: Human Bone Marrow Stromal Cells Exhibit Immunosuppressive Effects on Human T Lymphotropic Virus Type 1 T Lymphocyte from Infected Individuals.

Rodrigues ES, de Macedo MD, Orellana MD, Takayanagui OM, Palma PVB, Pinto MT, de Oliveira GLV, Malmegrim KCR, Slavov SN, Covas DT, Kashima S.

AIDS Res Hum Retroviruses. 2019 Feb;35(2):164-168. doi: 10.1089/AID.2018.0066. Epub 2018 Dec 22.

PMID:
30351194
25.

TAX-mRNA-Carrying Exosomes from Human T Cell Lymphotropic Virus Type 1-Infected Cells Can Induce Interferon-Gamma Production In Vitro.

Otaguiri KK, Dos Santos DF, Slavov SN, Depieri LV, Palma PVB, Meirelles FV, Covas DT, da Silveira JC, Kashima S.

AIDS Res Hum Retroviruses. 2018 Nov 1. doi: 10.1089/AID.2018.0115. [Epub ahead of print]

PMID:
30229663
26.

A microfluidic approach to study the effect of mechanical stress on erythrocytes in sickle cell disease.

Lizarralde Iragorri MA, El Hoss S, Brousse V, Lefevre SD, Dussiot M, Xu T, Ferreira AR, Lamarre Y, Silva Pinto AC, Kashima S, Lapouméroulie C, Covas DT, Le Van Kim C, Colin Y, Elion J, Français O, Le Pioufle B, El Nemer W.

Lab Chip. 2018 Sep 26;18(19):2975-2984. doi: 10.1039/c8lc00637g.

PMID:
30168832
27.

Image and motor behavior for monitoring tumor growth in C6 glioma model.

Souza TKF, Nucci MP, Mamani JB, da Silva HR, Fantacini DMC, de Souza LEB, Picanço-Castro V, Covas DT, Vidoto EL, Tannús A, Gamarra LF.

PLoS One. 2018 Jul 26;13(7):e0201453. doi: 10.1371/journal.pone.0201453. eCollection 2018.

28.

Patent mining and landscaping of emerging recombinant factor VIII through network analysis.

Pereira CG, Picanco-Castro V, Covas DT, Porto GS.

Nat Biotechnol. 2018 Jul 6;36(7):585-590. doi: 10.1038/nbt.4178. No abstract available.

PMID:
29979668
29.

Ex vivo evaluation of intravitreal mesenchymal stromal cell viability using bioluminescence imaging.

Vilela CAP, Souza LEB, Siqueira RC, Calado RT, Covas DT, Paula JS.

Stem Cell Res Ther. 2018 Jun 13;9(1):155. doi: 10.1186/s13287-018-0909-y.

30.

Detection of HTLV-1 proviral DNA in BM mononuclear cells and cultured mesenchymal stromal cells isolated from patients with HTLV-1 infection.

Rodrigues ES, do Carmo Favarin M, de Macedo MD, Otaguiri KK, Orellana MD, Takayanagui OM, Palma PVB, Slavov SN, Covas DT, Kashima S.

Virology. 2018 Jun;519:145-155. doi: 10.1016/j.virol.2018.04.014. Epub 2018 Apr 30.

31.

Homeostatic proliferation leads to telomere attrition and increased PD-1 expression after autologous hematopoietic SCT for systemic sclerosis.

Arruda LCM, Lima-Júnior JR, Clave E, Moraes DA, Douay C, Fournier I, Moins-Teisserenc H, Covas DT, Simões BP, Farge D, Toubert A, Malmegrim KCR, Oliveira MC.

Bone Marrow Transplant. 2018 Oct;53(10):1319-1327. doi: 10.1038/s41409-018-0162-0. Epub 2018 Apr 18.

PMID:
29670207
32.

Silent dengue virus circulation among asymptomatic blood donors from a hyperendemic Brazilian region.

Slavov SN, Hespanhol MR, Ferreira AR, Rodrigues ES, Covas DT, Kashima S.

Transfus Med. 2018 Dec;28(6):465-467. doi: 10.1111/tme.12521. Epub 2018 Mar 15. No abstract available.

PMID:
29542218
33.

Hematopoietic stem cells from induced pluripotent stem cells - considering the role of microRNA as a cell differentiation regulator.

Ferreira AF, Calin GA, Picanço-Castro V, Kashima S, Covas DT, de Castro FA.

J Cell Sci. 2018 Feb 21;131(4). pii: jcs203018. doi: 10.1242/jcs.203018. Review.

34.

Beneficial Role of Low-Intensity Laser Irradiation on Neural β-tubulin III Protein Expression in Human Bone Marrow Multipotent Mesenchymal Stromal Cells.

Ferreira-Silva V, Primo FL, Baqui MMA, Magalhães DAR, Orellana MD, Castilho-Fernandes A, Cruz MC, Câmara NOS, Covas DT, Tedesco AC.

Stem Cell Rev Rep. 2018 Aug;14(4):585-598. doi: 10.1007/s12015-017-9796-3.

PMID:
29442223
35.

Immune rebound associates with a favorable clinical response to autologous HSCT in systemic sclerosis patients.

Arruda LCM, Malmegrim KCR, Lima-Júnior JR, Clave E, Dias JBE, Moraes DA, Douay C, Fournier I, Moins-Teisserenc H, Alberdi AJ, Covas DT, Simões BP, Lansiaux P, Toubert A, Oliveira MC.

Blood Adv. 2018 Jan 23;2(2):126-141. doi: 10.1182/bloodadvances.2017011072.

36.

A Fully-Closed and Automated Hollow Fiber Bioreactor for Clinical-Grade Manufacturing of Human Mesenchymal Stem/Stromal Cells.

Mizukami A, de Abreu Neto MS, Moreira F, Fernandes-Platzgummer A, Huang YF, Milligan W, Cabral JMS, da Silva CL, Covas DT, Swiech K.

Stem Cell Rev Rep. 2018 Feb;14(1):141-143. doi: 10.1007/s12015-017-9787-4. No abstract available.

PMID:
29188439
37.

Comparative characterization of CD271+ and CD271- subpopulations of CD34+ human adipose-derived stromal cells.

Beckenkamp LR, Souza LEB, Melo FUF, Thomé CH, Magalhães DAR, Palma PVB, Covas DT.

J Cell Biochem. 2018 May;119(5):3873-3884. doi: 10.1002/jcb.26496. Epub 2018 Jan 19.

PMID:
29125884
38.

Functional analysis of HOXA10 and HOXB4 in human medulloblastoma cell lines.

Bonfim-Silva R, Ferreira Melo FU, Thomé CH, Abraham KJ, De Souza FAL, Ramalho FS, Machado HR, De Oliveira RS, Cardoso AA, Covas DT, Fontes AM.

Int J Oncol. 2017 Dec;51(6):1929-1940. doi: 10.3892/ijo.2017.4151. Epub 2017 Oct 10.

PMID:
29039487
39.

Pre-culture in endothelial growth medium enhances the angiogenic properties of adipose-derived stem/stromal cells.

Souza LEB, Beckenkamp LR, Sobral LM, Fantacini DMC, Melo FUF, Borges JS, Leopoldino AM, Kashima S, Covas DT.

Angiogenesis. 2018 Feb;21(1):15-22. doi: 10.1007/s10456-017-9579-0. Epub 2017 Oct 7.

PMID:
28988272
40.

Zika virus RNA detection in asymptomatic blood donors during an outbreak in the northeast region of São Paulo State, Brazil, 2016.

Slavov SN, Hespanhol MR, Rodrigues ES, Levi JE, Ubiali EMA, Covas DT, Kashima S.

Transfusion. 2017 Dec;57(12):2897-2901. doi: 10.1111/trf.14322. Epub 2017 Sep 16.

PMID:
28921551
41.

Quantification of Coagulation Factor VIII by Selective Reaction Monitoring.

do Nascimento Filho EG, Lanfredi GP, Abreu-Neto MS, Covas DT, Faça VM.

Methods Mol Biol. 2018;1674:275-282. doi: 10.1007/978-1-4939-7312-5_22.

PMID:
28921445
42.

Purification and Autoactivation Method for Recombinant Coagulation Factor VII.

Granovski V, Freitas MCC, Abreu-Neto MS, Covas DT.

Methods Mol Biol. 2018;1674:221-226. doi: 10.1007/978-1-4939-7312-5_18.

PMID:
28921441
43.

Purification Methods for Recombinant Factor VIII Expressed in Human Liver SK-Hep Cells.

Granovski V, Abreu-Neto MS, Covas DT.

Methods Mol Biol. 2018;1674:195-202. doi: 10.1007/978-1-4939-7312-5_15.

PMID:
28921438
44.

Human Cells as Platform to Produce Gamma-Carboxylated Proteins.

de Sousa Bomfim A, de Freitas MCC, Covas DT, de Sousa Russo EM.

Methods Mol Biol. 2018;1674:49-61. doi: 10.1007/978-1-4939-7312-5_4.

PMID:
28921427
45.

Expression differences of genes in the PI3K/AKT, WNT/b-catenin, SHH, NOTCH and MAPK signaling pathways in CD34+ hematopoietic cells obtained from chronic phase patients with chronic myeloid leukemia and from healthy controls.

de Cássia Viu Carrara R, Fontes AM, Abraham KJ, Orellana MD, Haddad SK, Palma PVB, Panepucci RA, Zago MA, Covas DT.

Clin Transl Oncol. 2018 Apr;20(4):542-549. doi: 10.1007/s12094-017-1751-x. Epub 2017 Sep 13.

PMID:
28905209
46.

Corrigendum to "The expression of Death Inducer-Obliterator (DIDO) variants in Myeloproliferative Neoplasms" [Blood Cells Mol. Dis. 59 (2016) 25-30].

Berzoti-Coelho MG, Ferreira AF, de Souza Nunes N, Tomazini Pinto M, Júnior MCR, Simões BP, Martínez-A C, Souto EX, Panepucci RA, Covas DT, Kashima S, Castro FA.

Blood Cells Mol Dis. 2018 Mar;69:123. doi: 10.1016/j.bcmd.2017.08.013. Epub 2017 Sep 4. No abstract available.

PMID:
28882478
47.

Induced Pluripotent Stem Cell for the Study and Treatment of Sickle Cell Anemia.

Junqueira Reis LC, Picanço-Castro V, Paes BCMF, Pereira OA, Gerdes Gyuricza I, de Araújo FT, Morato-Marques M, Moreira LF, Costa EBO, Dos Santos TPM, Covas DT, Pereira Carramaschi LDV, Russo EMS.

Stem Cells Int. 2017;2017:7492914. doi: 10.1155/2017/7492914. Epub 2017 Jul 26.

48.

Mesenchymal stem cells from sternum: the type of heart disease, ischemic or valvular, does not influence the cell culture establishment and growth kinetics.

Dias LD, Casali KR, Ghem C, da Silva MK, Sausen G, Palma PB, Covas DT, Kalil RAK, Schaan BD, Nardi NB, Markoski MM.

J Transl Med. 2017 Jul 25;15(1):161. doi: 10.1186/s12967-017-1262-0.

49.

Production of coagulation factor VII in human cell lines Sk-Hep-1 and HKB-11.

Corrêa de Freitas MC, Bomfim AS, Mizukami A, Picanço-Castro V, Swiech K, Covas DT.

Protein Expr Purif. 2017 Sep;137:26-33. doi: 10.1016/j.pep.2017.06.012. Epub 2017 Jun 23.

PMID:
28651975
50.

TGF-beta/atRA-induced Tregs express a selected set of microRNAs involved in the repression of transcripts related to Th17 differentiation.

Schiavinato JLDS, Haddad R, Saldanha-Araujo F, Baiochi J, Araujo AG, Santos Scheucher P, Covas DT, Zago MA, Panepucci RA.

Sci Rep. 2017 Jun 15;7(1):3627. doi: 10.1038/s41598-017-03456-8.

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