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Items: 21


Oxidative stress promotes pathologic polyploidization in nonalcoholic fatty liver disease.

Gentric G, Maillet V, Paradis V, Couton D, L'Hermitte A, Panasyuk G, Fromenty B, Celton-Morizur S, Desdouets C.

J Clin Invest. 2015 Mar 2;125(3):981-92. doi: 10.1172/JCI73957. Epub 2015 Jan 26.


Polyploidization without mitosis improves in vivo liver transduction with lentiviral vectors.

Pichard V, Couton D, Desdouets C, Ferry N.

Hum Gene Ther. 2013 Feb;24(2):143-51. doi: 10.1089/hum.2011.227. Epub 2013 Jan 30.


Polyploidy and liver proliferation: central role of insulin signaling.

Celton-Morizur S, Merlen G, Couton D, Desdouets C.

Cell Cycle. 2010 Feb 1;9(3):460-6. Epub 2010 Feb 6.


Protection against hepatocyte mitochondrial dysfunction delays fibrosis progression in mice.

Mitchell C, Robin MA, Mayeuf A, Mahrouf-Yorgov M, Mansouri A, Hamard M, Couton D, Fromenty B, Gilgenkrantz H.

Am J Pathol. 2009 Nov;175(5):1929-37. doi: 10.2353/ajpath.2009.090332. Epub 2009 Oct 1.


The insulin/Akt pathway controls a specific cell division program that leads to generation of binucleated tetraploid liver cells in rodents.

Celton-Morizur S, Merlen G, Couton D, Margall-Ducos G, Desdouets C.

J Clin Invest. 2009 Jul;119(7):1880-7.


Dual role of CCR2 in the constitution and the resolution of liver fibrosis in mice.

Mitchell C, Couton D, Couty JP, Anson M, Crain AM, Bizet V, Rénia L, Pol S, Mallet V, Gilgenkrantz H.

Am J Pathol. 2009 May;174(5):1766-75. doi: 10.2353/ajpath.2009.080632. Epub 2009 Apr 9.


Liver tetraploidization is controlled by a new process of incomplete cytokinesis.

Margall-Ducos G, Celton-Morizur S, Couton D, Brégerie O, Desdouets C.

J Cell Sci. 2007 Oct 15;120(Pt 20):3633-9. Epub 2007 Sep 25.


Transplanted hepatocytes over-expressing FoxM1B efficiently repopulate chronically injured mouse liver independent of donor age.

Brezillon N, Lambert-Blot M, Morosan S, Couton D, Mitchell C, Kremsdorf D, Costa RH, Gilgenkrantz H, Guidotti JE.

Mol Ther. 2007 Sep;15(9):1710-5. Epub 2007 Jun 12.


Delayed liver regeneration in mice lacking liver serum response factor.

Latasa MU, Couton D, Charvet C, Lafanechère A, Guidotti JE, Li Z, Tuil D, Daegelen D, Mitchell C, Gilgenkrantz H.

Am J Physiol Gastrointest Liver Physiol. 2007 Apr;292(4):G996-G1001. Epub 2006 Dec 14.


[Experimental modulation of apoptosis: physiopathological and therapeutic targets].

Mitchell C, Mallet V, Guidotti JE, Mignon A, Couton D, Kahn A, Gilgenkrantz H.

J Soc Biol. 2005;199(3):243-6. Review. French.


Interplay between FGF10 and Notch signalling is required for the self-renewal of pancreatic progenitors.

Miralles F, Lamotte L, Couton D, Joshi RL.

Int J Dev Biol. 2006;50(1):17-26.


Overexpression of beta2-adrenergic receptors in mouse liver alters the expression of gluconeogenic and glycolytic enzymes.

Erraji-Benchekroun L, Couton D, Postic C, Borde I, Gaston J, Guillet JG, André C.

Am J Physiol Endocrinol Metab. 2005 Apr;288(4):E715-22. Epub 2004 Dec 7.


beta2-adrenergic receptor-selective agonist clenbuterol prevents Fas-induced liver apoptosis and death in mice.

André C, Couton D, Gaston J, Erraji L, Renia L, Varlet P, Briand P, Guillet JG.

Am J Physiol. 1999 Mar;276(3):G647-54. doi: 10.1152/ajpgi.1999.276.3.G647.


The amino-terminal region of SV40 large T antigen is sufficient to induce hepatic tumours in mice.

Bennoun M, Grimber G, Couton D, Seye A, Molina T, Briand P, Joulin V.

Oncogene. 1998 Sep 10;17(10):1253-9.


Transient expression of genes transferred in vivo into heart using first-generation adenoviral vectors: role of the immune response.

Gilgenkrantz H, Duboc D, Juillard V, Couton D, Pavirani A, Guillet JG, Briand P, Kahn A.

Hum Gene Ther. 1995 Oct;6(10):1265-74.


Tat-induced lesions in transgenic mice do not correlate with the HIV-1 LTR transactivation.

Fergelot P, Molina T, Blanchet P, Grimber G, Duquenne O, Couton D, Zider A, Briand P, Cavard C.

C R Acad Sci III. 1995 Mar;318(3):329-37.


In vivo adenovirus-mediated gene transfer into ocular tissues.

Mashhour B, Couton D, Perricaudet M, Briand P.

Gene Ther. 1994 Mar;1(2):122-6.


Adenovirus-mediated transfer of a human dystrophin gene to skeletal muscle of mdx mouse.

Ragot T, Stratford-Perricaudet LD, Vincent N, Chafey P, Vigne E, Gilgenkrantz H, Couton D, Briand P, Kaplan JC, Kahn A, et al.

Gene Ther. 1994;1 Suppl 1:S53-4.


Long-term correction of mouse dystrophic degeneration by adenovirus-mediated transfer of a minidystrophin gene.

Vincent N, Ragot T, Gilgenkrantz H, Couton D, Chafey P, Grégoire A, Briand P, Kaplan JC, Kahn A, Perricaudet M.

Nat Genet. 1993 Oct;5(2):130-4.


Efficient adenovirus-mediated transfer of a human minidystrophin gene to skeletal muscle of mdx mice.

Ragot T, Vincent N, Chafey P, Vigne E, Gilgenkrantz H, Couton D, Cartaud J, Briand P, Kaplan JC, Perricaudet M, et al.

Nature. 1993 Feb 18;361(6413):647-50.


Dispensable role of the NF-kappa B sites in the UV-induction of the HIV-1 LTR in transgenic mice.

Zider A, Mashhour B, Fergelot P, Grimber G, Vernet M, Hazan U, Couton D, Briand P, Cavard C.

Nucleic Acids Res. 1993 Jan 11;21(1):79-86.

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