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Items: 31


The Wonder Years: What Can Primary School Children Teach Us About Immunity to Mycobacterium tuberculosis?

Seddon JA, Chiang SS, Esmail H, Coussens AK.

Front Immunol. 2018 Dec 13;9:2946. doi: 10.3389/fimmu.2018.02946. eCollection 2018. Review.


Neutrophils: Innate Effectors of TB Resistance?

Kroon EE, Coussens AK, Kinnear C, Orlova M, Möller M, Seeger A, Wilkinson RJ, Hoal EG, Schurr E.

Front Immunol. 2018 Nov 14;9:2637. doi: 10.3389/fimmu.2018.02637. eCollection 2018. Review.


Recent progress in understanding immune activation in the pathogenesis in HIV-tuberculosis co-infection.

du Bruyn E, Peton N, Esmail H, Howlett PJ, Coussens AK, Wilkinson RJ.

Curr Opin HIV AIDS. 2018 Nov;13(6):455-461. doi: 10.1097/COH.0000000000000501. Review.


Plasma Biomarkers to Detect Prevalent or Predict Progressive Tuberculosis Associated With Human Immunodeficiency Virus-1.

Lesosky M, Rangaka MX, Pienaar C, Coussens AK, Goliath R, Mathee S, Mwansa-Kambafwile J, Maartens G, Wilkinson RJ, Wilkinson KA.

Clin Infect Dis. 2019 Jul 2;69(2):295-305. doi: 10.1093/cid/ciy823.


Viral Apoptosis Evasion via the MAPK Pathway by Use of a Host Long Noncoding RNA.

Barichievy S, Naidoo J, Boullé M, Scholefield J, Parihar SP, Coussens AK, Brombacher F, Sigal A, Mhlanga MM.

Front Cell Infect Microbiol. 2018 Aug 3;8:263. doi: 10.3389/fcimb.2018.00263. eCollection 2018.


Complement pathway gene activation and rising circulating immune complexes characterize early disease in HIV-associated tuberculosis.

Esmail H, Lai RP, Lesosky M, Wilkinson KA, Graham CM, Horswell S, Coussens AK, Barry CE 3rd, O'Garra A, Wilkinson RJ.

Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):E964-E973. doi: 10.1073/pnas.1711853115. Epub 2018 Jan 16.


Paradoxical upgrading reaction in extra-pulmonary tuberculosis: association with vitamin D therapy.

Barr DA, Coussens AK, Irvine S, Ritchie ND, Herbert K, Choo-Kang B, Raeside D, Bell DJ, Seaton RA.

Int J Tuberc Lung Dis. 2017 Jun 1;21(6):677-683. doi: 10.5588/ijtld.16.0927.


Matrix Degradation in Human Immunodeficiency Virus Type 1-Associated Tuberculosis and Tuberculosis Immune Reconstitution Inflammatory Syndrome: A Prospective Observational Study.

Walker NF, Wilkinson KA, Meintjes G, Tezera LB, Goliath R, Peyper JM, Tadokera R, Opondo C, Coussens AK, Wilkinson RJ, Friedland JS, Elkington PT.

Clin Infect Dis. 2017 Jul 1;65(1):121-132. doi: 10.1093/cid/cix231.


Socio-political prescriptions for latent tuberculosis infection are required to prevent reactivation of tuberculosis.

Coussens AK, Mason PH, Oni T.

Int J Infect Dis. 2017 May;58:115-116. doi: 10.1016/j.ijid.2017.01.033. Epub 2017 Feb 1. No abstract available.


Human Immunology of Tuberculosis.

Scriba TJ, Coussens AK, Fletcher HA.

Microbiol Spectr. 2017 Jan;5(1). doi: 10.1128/microbiolspec.TBTB2-0016-2016. Review.


The role of UV radiation and vitamin D in the seasonality and outcomes of infectious disease.

Abhimanyu, Coussens AK.

Photochem Photobiol Sci. 2017 Mar 16;16(3):314-338. doi: 10.1039/c6pp00355a. Review.


Tuberculosis prevention must integrate technological and basic care innovation.

Mason PH, Oni T, van Herpen MM, Coussens AK.

Eur Respir J. 2016 Nov;48(5):1529-1531. doi: 10.1183/13993003.01449-2016. No abstract available.


Vitamin D Status and Its Consequences for Health in South Africa.

Norval M, Coussens AK, Wilkinson RJ, Bornman L, Lucas RM, Wright CY.

Int J Environ Res Public Health. 2016 Oct 18;13(10). pii: E1019. Review.


Human Immunology of Tuberculosis.

Scriba TJ, Coussens AK, Fletcher HA.

Microbiol Spectr. 2016 Oct;4(5). doi: 10.1128/microbiolspec.TBTB2-0016-2016. Review.


Human Immunology of Tuberculosis.

Scriba TJ, Coussens AK, Fletcher HA.

Microbiol Spectr. 2016 Aug;4(4). doi: 10.1128/microbiolspec.TBTB2-0016-2016. Review.


Characterization of progressive HIV-associated tuberculosis using 2-deoxy-2-[18F]fluoro-D-glucose positron emission and computed tomography.

Esmail H, Lai RP, Lesosky M, Wilkinson KA, Graham CM, Coussens AK, Oni T, Warwick JM, Said-Hartley Q, Koegelenberg CF, Walzl G, Flynn JL, Young DB, Barry Iii CE, O'Garra A, Wilkinson RJ.

Nat Med. 2016 Oct;22(10):1090-1093. doi: 10.1038/nm.4161. Epub 2016 Sep 5.


Relationship Between HIV Coinfection, Interleukin 10 Production, and Mycobacterium tuberculosis in Human Lymph Node Granulomas.

Diedrich CR, O'Hern J, Gutierrez MG, Allie N, Papier P, Meintjes G, Coussens AK, Wainwright H, Wilkinson RJ.

J Infect Dis. 2016 Nov 1;214(9):1309-1318. Epub 2016 Jul 26.


Phenylbutyrate Is Bacteriostatic against Mycobacterium tuberculosis and Regulates the Macrophage Response to Infection, Synergistically with 25-Hydroxy-Vitamin D3.

Coussens AK, Wilkinson RJ, Martineau AR.

PLoS Pathog. 2015 Jul 2;11(7):e1005007. doi: 10.1371/journal.ppat.1005007. eCollection 2015 Jul.


High-dose vitamin D3 reduces deficiency caused by low UVB exposure and limits HIV-1 replication in urban Southern Africans.

Coussens AK, Naude CE, Goliath R, Chaplin G, Wilkinson RJ, Jablonski NG.

Proc Natl Acad Sci U S A. 2015 Jun 30;112(26):8052-7. doi: 10.1073/pnas.1500909112. Epub 2015 Jun 15.


Tricks to translating TB transcriptomics.

Deffur A, Wilkinson RJ, Coussens AK.

Ann Transl Med. 2015 May;3(Suppl 1):S43. doi: 10.3978/j.issn.2305-5839.2015.04.12.


Neutrophil-associated central nervous system inflammation in tuberculous meningitis immune reconstitution inflammatory syndrome.

Marais S, Wilkinson KA, Lesosky M, Coussens AK, Deffur A, Pepper DJ, Schutz C, Ismail Z, Meintjes G, Wilkinson RJ.

Clin Infect Dis. 2014 Dec 1;59(11):1638-47. doi: 10.1093/cid/ciu641. Epub 2014 Aug 8.


Anti-Inflammatory and Antimicrobial Actions of Vitamin D in Combating TB/HIV.

Coussens AK, Martineau AR, Wilkinson RJ.

Scientifica (Cairo). 2014;2014:903680. doi: 10.1155/2014/903680. Epub 2014 Jul 2. Review.


Regulation of CYP27B1 and CYP24A1 hydroxylases limits cell-autonomous activation of vitamin D in dendritic cells.

Kundu R, Chain BM, Coussens AK, Khoo B, Noursadeghi M.

Eur J Immunol. 2014 Jun;44(6):1781-90. doi: 10.1002/eji.201344157. Epub 2014 Apr 10.


Ethnic variation in inflammatory profile in tuberculosis.

Coussens AK, Wilkinson RJ, Nikolayevskyy V, Elkington PT, Hanifa Y, Islam K, Timms PM, Bothamley GH, Claxton AP, Packe GE, Darmalingam M, Davidson RN, Milburn HJ, Baker LV, Barker RD, Drobniewski FA, Mein CA, Bhaw-Rosun L, Nuamah RA, Griffiths CJ, Martineau AR.

PLoS Pathog. 2013;9(7):e1003468. doi: 10.1371/journal.ppat.1003468. Epub 2013 Jul 4.


Vitamin D accelerates resolution of inflammatory responses during tuberculosis treatment.

Coussens AK, Wilkinson RJ, Hanifa Y, Nikolayevskyy V, Elkington PT, Islam K, Timms PM, Venton TR, Bothamley GH, Packe GE, Darmalingam M, Davidson RN, Milburn HJ, Baker LV, Barker RD, Mein CA, Bhaw-Rosun L, Nuamah R, Young DB, Drobniewski FA, Griffiths CJ, Martineau AR.

Proc Natl Acad Sci U S A. 2012 Sep 18;109(38):15449-54. Epub 2012 Sep 4.


Corticosteroid therapy, vitamin D status, and inflammatory cytokine profile in the HIV-tuberculosis immune reconstitution inflammatory syndrome.

Conesa-Botella A, Meintjes G, Coussens AK, van der Plas H, Goliath R, Schutz C, Moreno-Reyes R, Mehta M, Martineau AR, Wilkinson RJ, Colebunders R, Wilkinson KA.

Clin Infect Dis. 2012 Oct;55(7):1004-11. doi: 10.1093/cid/cis577. Epub 2012 Jun 19.


High-dose vitamin D(3) during intensive-phase antimicrobial treatment of pulmonary tuberculosis: a double-blind randomised controlled trial.

Martineau AR, Timms PM, Bothamley GH, Hanifa Y, Islam K, Claxton AP, Packe GE, Moore-Gillon JC, Darmalingam M, Davidson RN, Milburn HJ, Baker LV, Barker RD, Woodward NJ, Venton TR, Barnes KE, Mullett CJ, Coussens AK, Rutterford CM, Mein CA, Davies GR, Wilkinson RJ, Nikolayevskyy V, Drobniewski FA, Eldridge SM, Griffiths CJ.

Lancet. 2011 Jan 15;377(9761):242-50. doi: 10.1016/S0140-6736(10)61889-2. Epub 2011 Jan 5.


In vitro differentiation of human calvarial suture derived cells with and without dexamethasone does not induce in vivo-like expression.

Coussens AK, Hughes IP, Morris CP, Powell BC, Anderson PJ.

J Cell Physiol. 2009 Jan;218(1):183-91. doi: 10.1002/jcp.21586.


Identification of genes differentially expressed by prematurely fused human sutures using a novel in vivo - in vitro approach.

Coussens AK, Hughes IP, Wilkinson CR, Morris CP, Anderson PJ, Powell BC, van Daal A.

Differentiation. 2008 May;76(5):531-45. Epub 2007 Dec 17.


Unravelling the molecular control of calvarial suture fusion in children with craniosynostosis.

Coussens AK, Wilkinson CR, Hughes IP, Morris CP, van Daal A, Anderson PJ, Powell BC.

BMC Genomics. 2007 Dec 12;8:458.


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