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Items: 1 to 50 of 52

1.

Expression of a dominant negative estrogen receptor alpha variant in transgenic mice accelerates uterine cancer induced by the potent estrogen diethylstilbestrol.

Davis VL, Newbold RR, Couse JF, Rea SL, Gallagher KM, Hamilton KJ, Goulding EH, Jefferson W, Eddy EM, Bullock BC, Korach KS.

Reprod Toxicol. 2012 Dec;34(4):512-21. doi: 10.1016/j.reprotox.2012.08.005. Epub 2012 Aug 31.

2.

Estrogen receptor-α mediates diethylstilbestrol-induced feminization of the seminal vesicle in male mice.

Walker VR, Jefferson WN, Couse JF, Korach KS.

Environ Health Perspect. 2012 Apr;120(4):560-5. doi: 10.1289/ehp.1103678. Epub 2012 Jan 24.

3.

Estradiol induction of spermatogenesis is mediated via an estrogen receptor-{alpha} mechanism involving neuroendocrine activation of follicle-stimulating hormone secretion.

Allan CM, Couse JF, Simanainen U, Spaliviero J, Jimenez M, Rodriguez K, Korach KS, Handelsman DJ.

Endocrinology. 2010 Jun;151(6):2800-10. doi: 10.1210/en.2009-1477. Epub 2010 Apr 21.

4.

Expression of basigin in reproductive tissues of estrogen receptor-{alpha} or -{beta} null mice.

Chen L, Bi J, Nakai M, Bunick D, Couse JF, Korach KS, Nowak RA.

Reproduction. 2010 Jun;139(6):1057-66. doi: 10.1530/REP-10-0069. Epub 2010 Apr 13.

5.

Insufficient luteinizing hormone-induced intracellular signaling disrupts ovulation in preovulatory follicles lacking estrogen receptor-{beta}.

Rodriguez KF, Couse JF, Jayes FL, Hamilton KJ, Burns KA, Taniguchi F, Korach KS.

Endocrinology. 2010 Jun;151(6):2826-34. doi: 10.1210/en.2009-1446. Epub 2010 Apr 8.

6.

Estrogen receptor beta is required for optimal cAMP production in mouse granulosa cells.

Deroo BJ, Rodriguez KF, Couse JF, Hamilton KJ, Collins JB, Grissom SF, Korach KS.

Mol Endocrinol. 2009 Jul;23(7):955-65. doi: 10.1210/me.2008-0213. Epub 2009 Mar 26.

7.

Increased blood pressure in mice lacking cytochrome P450 2J5.

Athirakul K, Bradbury JA, Graves JP, DeGraff LM, Ma J, Zhao Y, Couse JF, Quigley R, Harder DR, Zhao X, Imig JD, Pedersen TL, Newman JW, Hammock BD, Conley AJ, Korach KS, Coffman TM, Zeldin DC.

FASEB J. 2008 Dec;22(12):4096-108. doi: 10.1096/fj.08-114413. Epub 2008 Aug 20.

8.
9.

The bi-modal effects of estradiol on gonadotropin synthesis and secretion in female mice are dependent on estrogen receptor-alpha.

Lindzey J, Jayes FL, Yates MM, Couse JF, Korach KS.

J Endocrinol. 2006 Oct;191(1):309-17.

PMID:
17065413
10.

The intraovarian actions of estrogen receptor-alpha are necessary to repress the formation of morphological and functional Leydig-like cells in the female gonad.

Couse JF, Yates MM, Rodriguez KF, Johnson JA, Poirier D, Korach KS.

Endocrinology. 2006 Aug;147(8):3666-78. Epub 2006 Apr 20.

11.

17beta-estradiol induces apoptosis in the developing rodent prostate independently of ERalpha or ERbeta.

Taylor RA, Cowin P, Couse JF, Korach KS, Risbridger GP.

Endocrinology. 2006 Jan;147(1):191-200. Epub 2005 Oct 13.

PMID:
16223864
12.

Upregulation of estrogen receptor expression in the uterus of ovariectomized B6C3F1 mice and Ishikawa cells treated with bromoethane.

Aoyama H, Couse JF, Hewitt SC, Haseman JK, He H, Zheng X, Majstoravich S, Korach KS, Dixon D.

Toxicol Appl Pharmacol. 2005 Dec 15;209(3):226-35.

PMID:
15922381
13.

Estrogen receptor-beta is critical to granulosa cell differentiation and the ovulatory response to gonadotropins.

Couse JF, Yates MM, Deroo BJ, Korach KS.

Endocrinology. 2005 Aug;146(8):3247-62. Epub 2005 Apr 14.

PMID:
15831568
14.

Increased mortality and aggravation of heart failure in estrogen receptor-beta knockout mice after myocardial infarction.

Pelzer T, Loza PA, Hu K, Bayer B, Dienesch C, Calvillo L, Couse JF, Korach KS, Neyses L, Ertl G.

Circulation. 2005 Mar 29;111(12):1492-8. Epub 2005 Mar 21.

PMID:
15781739
15.

In vitro growth and ovulation of follicles from ovaries of estrogen receptor (ER){alpha} and ER{beta} null mice indicate a role for ER{beta} in follicular maturation.

Emmen JM, Couse JF, Elmore SA, Yates MM, Kissling GE, Korach KS.

Endocrinology. 2005 Jun;146(6):2817-26. Epub 2005 Feb 24.

PMID:
15731357
16.
17.

Formation of cystic ovarian follicles associated with elevated luteinizing hormone requires estrogen receptor-beta.

Couse JF, Yates MM, Sanford R, Nyska A, Nilson JH, Korach KS.

Endocrinology. 2004 Oct;145(10):4693-702. Epub 2004 Jul 1.

PMID:
15231698
18.

Update on animal models developed for analyses of estrogen receptor biological activity.

Korach KS, Emmen JM, Walker VR, Hewitt SC, Yates M, Hall JM, Swope DL, Harrell JC, Couse JF.

J Steroid Biochem Mol Biol. 2003 Sep;86(3-5):387-91. Review.

PMID:
14623535
19.
20.
21.

An estrogen receptor repressor induces cataract formation in transgenic mice.

Davis VL, Chan CC, Schoen TJ, Couse JF, Chader GJ, Korach KS.

Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9427-32. Epub 2002 Jun 24.

22.

Prostate phenotypes in estrogen-modulated transgenic mice.

Jarred RA, McPherson SJ, Bianco JJ, Couse JF, Korach KS, Risbridger GP.

Trends Endocrinol Metab. 2002 May-Jun;13(4):163-8. Review.

PMID:
11943560
23.

Contrasting phenotypes in reproductive tissues of female estrogen receptor null mice.

Couse JF, Korach KS.

Ann N Y Acad Sci. 2001 Dec;948:1-8. Review.

PMID:
11795387
24.
25.

Estrogen imprinting of the developing prostate gland is mediated through stromal estrogen receptor alpha: studies with alphaERKO and betaERKO mice.

Prins GS, Birch L, Couse JF, Choi I, Katzenellenbogen B, Korach KS.

Cancer Res. 2001 Aug 15;61(16):6089-97.

26.

The multifaceted mechanisms of estradiol and estrogen receptor signaling.

Hall JM, Couse JF, Korach KS.

J Biol Chem. 2001 Oct 5;276(40):36869-72. Epub 2001 Jul 17. Review. No abstract available.

27.
28.

Receptor null mice reveal contrasting roles for estrogen receptor alpha and beta in reproductive tissues.

Couse JF, Curtis Hewitt S, Korach KS.

J Steroid Biochem Mol Biol. 2000 Nov 30;74(5):287-96. Review. No abstract available.

PMID:
11162937
29.

17beta-estradiol and ICI-182780 regulate the hair follicle cycle in mice through an estrogen receptor-alpha pathway.

Chanda S, Robinette CL, Couse JF, Smart RC.

Am J Physiol Endocrinol Metab. 2000 Feb;278(2):E202-10.

30.

Expression of estrogen receptor beta is developmentally regulated in reproductive tissues of male and female mice.

Jefferson WN, Couse JF, Banks EP, Korach KS, Newbold RR.

Biol Reprod. 2000 Feb;62(2):310-7.

PMID:
10642567
31.

Postnatal sex reversal of the ovaries in mice lacking estrogen receptors alpha and beta.

Couse JF, Hewitt SC, Bunch DO, Sar M, Walker VR, Davis BJ, Korach KS.

Science. 1999 Dec 17;286(5448):2328-31.

32.

Prevention of the polycystic ovarian phenotype and characterization of ovulatory capacity in the estrogen receptor-alpha knockout mouse.

Couse JF, Bunch DO, Lindzey J, Schomberg DW, Korach KS.

Endocrinology. 1999 Dec;140(12):5855-65.

PMID:
10579351
33.

Reproductive phenotypes in the estrogen receptor-alpha knockout mouse.

Couse JF, Korach KS.

Ann Endocrinol (Paris). 1999 Jul;60(2):143-8. Review.

PMID:
10456188
34.

Estrogen receptor null mice: what have we learned and where will they lead us?

Couse JF, Korach KS.

Endocr Rev. 1999 Jun;20(3):358-417. Review. Erratum in: Endocr Rev 1999 Aug;20(4):459.

PMID:
10368776
35.

Targeted disruption of the estrogen receptor-alpha gene in female mice: characterization of ovarian responses and phenotype in the adult.

Schomberg DW, Couse JF, Mukherjee A, Lubahn DB, Sar M, Mayo KE, Korach KS.

Endocrinology. 1999 Jun;140(6):2733-44.

PMID:
10342864
36.

A mouse mammary tumor virus-Wnt-1 transgene induces mammary gland hyperplasia and tumorigenesis in mice lacking estrogen receptor-alpha.

Bocchinfuso WP, Hively WP, Couse JF, Varmus HE, Korach KS.

Cancer Res. 1999 Apr 15;59(8):1869-76.

37.

Generation and reproductive phenotypes of mice lacking estrogen receptor beta.

Krege JH, Hodgin JB, Couse JF, Enmark E, Warner M, Mahler JF, Sar M, Korach KS, Gustafsson JA, Smithies O.

Proc Natl Acad Sci U S A. 1998 Dec 22;95(26):15677-82.

39.

Exploring the role of sex steroids through studies of receptor deficient mice.

Couse JF, Korach KS.

J Mol Med (Berl). 1998 Jun;76(7):497-511. Review.

PMID:
9660168
40.

The role of estrogen receptors and androgen receptors in sex steroid regulation of B lymphopoiesis.

Smithson G, Couse JF, Lubahn DB, Korach KS, Kincade PW.

J Immunol. 1998 Jul 1;161(1):27-34.

42.

Disruption of the estrogen receptor gene in mice.

Dixon D, Couse JF, Korach KS.

Toxicol Pathol. 1997 Sep-Oct;25(5):518-20. No abstract available.

PMID:
9323845
43.

Accelerated onset of uterine tumors in transgenic mice with aberrant expression of the estrogen receptor after neonatal exposure to diethylstilbestrol.

Couse JF, Davis VL, Hanson RB, Jefferson WN, McLachlan JA, Bullock BC, Newbold RR, Korach KS.

Mol Carcinog. 1997 Aug;19(4):236-42.

PMID:
9290700
44.

Vascular estrogen receptors and endothelium-derived nitric oxide production in the mouse aorta. Gender difference and effect of estrogen receptor gene disruption.

Rubanyi GM, Freay AD, Kauser K, Sukovich D, Burton G, Lubahn DB, Couse JF, Curtis SW, Korach KS.

J Clin Invest. 1997 May 15;99(10):2429-37.

45.

Physiological coupling of growth factor and steroid receptor signaling pathways: estrogen receptor knockout mice lack estrogen-like response to epidermal growth factor.

Curtis SW, Washburn T, Sewall C, DiAugustine R, Lindzey J, Couse JF, Korach KS.

Proc Natl Acad Sci U S A. 1996 Oct 29;93(22):12626-30.

46.

Estrogen receptor gene disruption: molecular characterization and experimental and clinical phenotypes.

Korach KS, Couse JF, Curtis SW, Washburn TF, Lindzey J, Kimbro KS, Eddy EM, Migliaccio S, Snedeker SM, Lubahn DB, Schomberg DW, Smith EP.

Recent Prog Horm Res. 1996;51:159-86; discussion 186-8. Review.

PMID:
8701078
47.

Disruption of the mouse oestrogen receptor gene: resulting phenotypes and experimental findings.

Couse JF, Curtis SW, Washburn TF, Eddy EM, Schomberg DW, Korach KS.

Biochem Soc Trans. 1995 Nov;23(4):929-35. No abstract available.

PMID:
8654869
48.

Analysis of transcription and estrogen insensitivity in the female mouse after targeted disruption of the estrogen receptor gene.

Couse JF, Curtis SW, Washburn TF, Lindzey J, Golding TS, Lubahn DB, Smithies O, Korach KS.

Mol Endocrinol. 1995 Nov;9(11):1441-54.

PMID:
8584021
49.

An improved method of genomic DNA extraction for screening transgenic mice.

Couse JF, Davis VL, Tally WC, Korach KS.

Biotechniques. 1994 Dec;17(6):1030-2. No abstract available.

PMID:
7873170
50.

Aberrant reproductive phenotypes evident in transgenic mice expressing the wild-type mouse estrogen receptor.

Davis VL, Couse JF, Goulding EH, Power SG, Eddy EM, Korach KS.

Endocrinology. 1994 Jul;135(1):379-86.

PMID:
8013372

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