Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 435


Population-based inference of aminoglycoside resistance mechanisms in Escherichia coli.

Mancini S, Marchesi M, Imkamp F, Wagner K, Keller PM, Quiblier C, Bodendoerfer E, Courvalin P, Böttger EC.

EBioMedicine. 2019 Aug;46:184-192. doi: 10.1016/j.ebiom.2019.07.020. Epub 2019 Jul 12.


Combining forecast probabilities with graphical visualization for improved reporting of antimicrobial susceptibility testing.

Mancini S, Marchesi M, Blöchliger N, Schmid M, Courvalin P, Keller PM, Böttger EC.

J Antimicrob Chemother. 2018 Aug 1;73(8):2266-2268. doi: 10.1093/jac/dky138. No abstract available.


Deciphering Multifactorial Resistance Phenotypes in Acinetobacter baumannii by Genomics and Targeted Label-free Proteomics.

Cecchini T, Yoon EJ, Charretier Y, Bardet C, Beaulieu C, Lacoux X, Docquier JD, Lemoine J, Courvalin P, Grillot-Courvalin C, Charrier JP.

Mol Cell Proteomics. 2018 Mar;17(3):442-456. doi: 10.1074/mcp.RA117.000107. Epub 2017 Dec 19.


New aminoglycoside-modifying enzymes APH(3')-VIII and APH(3')-IX in Acinetobacter rudis and Acinetobacter gerneri.

Yoon EJ, Grillot-Courvalin C, Courvalin P.

J Antibiot (Tokyo). 2017 Apr;70(4):400-403. doi: 10.1038/ja.2016.144. Epub 2016 Dec 14.


First Detection of GES-5 Carbapenemase-Producing Acinetobacter baumannii Isolate.

Al-Agamy MH, Jeannot K, El-Mahdy TS, Shibl AM, Kattan W, Plésiat P, Courvalin P.

Microb Drug Resist. 2017 Jul;23(5):556-562. doi: 10.1089/mdr.2016.0152. Epub 2016 Nov 17.


Structural and Biochemical Characterization of Acinetobacter spp. Aminoglycoside Acetyltransferases Highlights Functional and Evolutionary Variation among Antibiotic Resistance Enzymes.

Stogios PJ, Kuhn ML, Evdokimova E, Law M, Courvalin P, Savchenko A.

ACS Infect Dis. 2017 Feb 10;3(2):132-143. doi: 10.1021/acsinfecdis.6b00058. Epub 2016 Nov 10.


Diversity of Molecular Mechanisms Conferring Carbapenem Resistance to Pseudomonas aeruginosa Isolates from Saudi Arabia.

Al-Agamy MH, Jeannot K, El-Mahdy TS, Samaha HA, Shibl AM, Plésiat P, Courvalin P.

Can J Infect Dis Med Microbiol. 2016;2016:4379686. doi: 10.1155/2016/4379686. Epub 2016 Aug 11.


Contribution of the Ade Resistance-Nodulation-Cell Division-Type Efflux Pumps to Fitness and Pathogenesis of Acinetobacter baumannii.

Yoon EJ, Balloy V, Fiette L, Chignard M, Courvalin P, Grillot-Courvalin C.

MBio. 2016 May 31;7(3). pii: e00697-16. doi: 10.1128/mBio.00697-16.


A penicillin- and metronidazole-resistant Clostridium botulinum strain responsible for an infant botulism case.

Mazuet C, Yoon EJ, Boyer S, Pignier S, Blanc T, Doehring I, Meziane-Cherif D, Dumant-Forest C, Sautereau J, Legeay C, Bouvet P, Bouchier C, Quijano-Roy S, Pestel-Caron M, Courvalin P, Popoff MR.

Clin Microbiol Infect. 2016 Jul;22(7):644.e7-644.e12. doi: 10.1016/j.cmi.2016.04.011. Epub 2016 Apr 21.


Why is antibiotic resistance a deadly emerging disease?

Courvalin P.

Clin Microbiol Infect. 2016 May;22(5):405-7. doi: 10.1016/j.cmi.2016.01.012. Epub 2016 Jan 22. Review.


Origin in Acinetobacter gyllenbergii and dissemination of aminoglycoside-modifying enzyme AAC(6')-Ih.

Yoon EJ, Goussard S, Nemec A, Lambert T, Courvalin P, Grillot-Courvalin C.

J Antimicrob Chemother. 2016 Mar;71(3):601-6. doi: 10.1093/jac/dkv390. Epub 2015 Dec 7.


Structural insights into the loss of penicillinase and the gain of ceftazidimase activities by OXA-145 β-lactamase in Pseudomonas aeruginosa.

Meziane-Cherif D, Bonnet R, Haouz A, Courvalin P.

J Antimicrob Chemother. 2016 Feb;71(2):395-402. doi: 10.1093/jac/dkv375. Epub 2015 Nov 14.


Structural and Functional Adaptation of Vancomycin Resistance VanT Serine Racemases.

Meziane-Cherif D, Stogios PJ, Evdokimova E, Egorova O, Savchenko A, Courvalin P.

MBio. 2015 Aug 11;6(4):e00806. doi: 10.1128/mBio.00806-15.


AAC(3)-XI, a new aminoglycoside 3-N-acetyltransferase from Corynebacterium striatum.

Galimand M, Fishovitz J, Lambert T, Barbe V, Zajicek J, Mobashery S, Courvalin P.

Antimicrob Agents Chemother. 2015 Sep;59(9):5647-53. doi: 10.1128/AAC.01203-15. Epub 2015 Jul 6.


Structural and functional plasticity of antibiotic resistance nucleotidylyltransferases revealed by molecular characterization of lincosamide nucleotidylyltransferases lnu(A) and lnu(D).

Stogios PJ, Evdokimova E, Morar M, Koteva K, Wright GD, Courvalin P, Savchenko A.

J Mol Biol. 2015 Jun 19;427(12):2229-43. doi: 10.1016/j.jmb.2015.04.008. Epub 2015 Apr 18.


Competition between VanU(G) repressor and VanR(G) activator leads to rheostatic control of vanG vancomycin resistance operon expression.

Depardieu F, Mejean V, Courvalin P.

PLoS Genet. 2015 Apr 21;11(4):e1005170. doi: 10.1371/journal.pgen.1005170. eCollection 2015 Apr.


Contribution of resistance-nodulation-cell division efflux systems to antibiotic resistance and biofilm formation in Acinetobacter baumannii.

Yoon EJ, Chabane YN, Goussard S, Snesrud E, Courvalin P, Dé E, Grillot-Courvalin C.

MBio. 2015 Mar 24;6(2). pii: e00309-15. doi: 10.1128/mBio.00309-15.


A vanG-type locus in Clostridium argentinense.

Berthet N, Périchon B, Mazuet C, Chapetón-Montes D, Bouchier C, Bouvet P, Legeay C, Popoff MR, Courvalin P.

J Antimicrob Chemother. 2015 Jul;70(7):1942-5. doi: 10.1093/jac/dkv073. Epub 2015 Mar 22.


Antimicrobial Activity of Plectasin NZ2114 in Combination with Cell Wall Targeting Antibiotics Against VanA-Type Enterococcus faecalis.

Breidenstein EB, Courvalin P, Meziane-Cherif D.

Microb Drug Resist. 2015 Aug;21(4):373-9. doi: 10.1089/mdr.2014.0221. Epub 2015 Mar 18.


The Resistant-Population Cutoff (RCOFF): a New Concept for Improved Characterization of Antimicrobial Susceptibility Patterns of Non-Wild-Type Bacterial Populations.

Valsesia G, Hombach M, Maurer FP, Courvalin P, Roos M, Böttger EC.

J Clin Microbiol. 2015 Jun;53(6):1806-11. doi: 10.1128/JCM.03505-14. Epub 2015 Mar 11.


The clinical positioning of telavancin in Europe.

Masterton R, Cornaglia G, Courvalin P, Lode HM, Rello J, Torres A.

Int J Antimicrob Agents. 2015 Mar;45(3):213-20. doi: 10.1016/j.ijantimicag.2014.12.006. Epub 2014 Dec 24. Review.


Molecular epidemiology of carbapenem non-susceptible Acinetobacter baumannii in France.

Jeannot K, Diancourt L, Vaux S, Thouverez M, Ribeiro A, Coignard B, Courvalin P, Brisse S.

PLoS One. 2014 Dec 17;9(12):e115452. doi: 10.1371/journal.pone.0115452. eCollection 2014.


Origin in Acinetobacter guillouiae and dissemination of the aminoglycoside-modifying enzyme Aph(3')-VI.

Yoon EJ, Goussard S, Touchon M, Krizova L, Cerqueira G, Murphy C, Lambert T, Grillot-Courvalin C, Nemec A, Courvalin P.

MBio. 2014 Oct 21;5(5):e01972-14. doi: 10.1128/mBio.01972-14.


The genomic diversification of the whole Acinetobacter genus: origins, mechanisms, and consequences.

Touchon M, Cury J, Yoon EJ, Krizova L, Cerqueira GC, Murphy C, Feldgarden M, Wortman J, Clermont D, Lambert T, Grillot-Courvalin C, Nemec A, Courvalin P, Rocha EP.

Genome Biol Evol. 2014 Oct 13;6(10):2866-82. doi: 10.1093/gbe/evu225.


Potential for reduction of streptogramin A resistance revealed by structural analysis of acetyltransferase VatA.

Stogios PJ, Kuhn ML, Evdokimova E, Courvalin P, Anderson WF, Savchenko A.

Antimicrob Agents Chemother. 2014 Dec;58(12):7083-92. doi: 10.1128/AAC.03743-14. Epub 2014 Sep 15.


Overexpression of the novel MATE fluoroquinolone efflux pump FepA in Listeria monocytogenes is driven by inactivation of its local repressor FepR.

Guérin F, Galimand M, Tuambilangana F, Courvalin P, Cattoir V.

PLoS One. 2014 Sep 4;9(9):e106340. doi: 10.1371/journal.pone.0106340. eCollection 2014.


Integrating forecast probabilities in antibiograms: a way to guide antimicrobial prescriptions more reliably?

Maurer FP, Courvalin P, Böttger EC, Hombach M.

J Clin Microbiol. 2014 Oct;52(10):3674-84. doi: 10.1128/JCM.01645-14. Epub 2014 Aug 6.


Antibiotic resistance: to the rescue of old drugs.

Meziane-Cherif D, Courvalin P.

Nature. 2014 Jun 26;510(7506):477-8. doi: 10.1038/510477a. No abstract available.


Validation of antibiotic susceptibility testing guidelines in a routine clinical microbiology laboratory exemplifies general key challenges in setting clinical breakpoints.

Hombach M, Courvalin P, Böttger EC.

Antimicrob Agents Chemother. 2014 Jul;58(7):3921-6. doi: 10.1128/AAC.02489-13. Epub 2014 Apr 28.


Amplification of aminoglycoside resistance gene aphA1 in Acinetobacter baumannii results in tobramycin therapy failure.

McGann P, Courvalin P, Snesrud E, Clifford RJ, Yoon EJ, Onmus-Leone F, Ong AC, Kwak YI, Grillot-Courvalin C, Lesho E, Waterman PE.

MBio. 2014 Apr 22;5(2):e00915. doi: 10.1128/mBio.00915-14.


Structural basis for the evolution of vancomycin resistance D,D-peptidases.

Meziane-Cherif D, Stogios PJ, Evdokimova E, Savchenko A, Courvalin P.

Proc Natl Acad Sci U S A. 2014 Apr 22;111(16):5872-7. doi: 10.1073/pnas.1402259111. Epub 2014 Apr 7.


The survival of influenza A(H1N1)pdm09 virus on 4 household surfaces.

Oxford J, Berezin EN, Courvalin P, Dwyer DE, Exner M, Jana LA, Kaku M, Lee C, Letlape K, Low DE, Madani TA, Rubino JR, Saini N, Schoub BD, Signorelli C, Tierno PM, Zhong X.

Am J Infect Control. 2014 Apr;42(4):423-5. doi: 10.1016/j.ajic.2013.10.016.


Aminoglycoside resistance 16S rRNA methyltransferases block endogenous methylation, affect translation efficiency and fitness of the host.

Lioy VS, Goussard S, Guerineau V, Yoon EJ, Courvalin P, Galimand M, Grillot-Courvalin C.

RNA. 2014 Mar;20(3):382-91. doi: 10.1261/rna.042572.113. Epub 2014 Jan 7.


Functional motions modulating VanA ligand binding unraveled by self-organizing maps.

Bouvier G, Duclert-Savatier N, Desdouits N, Meziane-Cherif D, Blondel A, Courvalin P, Nilges M, Malliavin TE.

J Chem Inf Model. 2014 Jan 27;54(1):289-301. doi: 10.1021/ci400354b. Epub 2014 Jan 15.


Highly rifampin-resistant Listeria monocytogenes isolated from a patient with prosthetic bone infection.

Chenal-Francisque V, Charlier C, Mehvish S, Dieye H, Leclercq A, Courvalin P, Lecuit M.

Antimicrob Agents Chemother. 2014;58(3):1829-30. doi: 10.1128/AAC.02449-13. Epub 2014 Jan 6. No abstract available.


Identification of 50 class D β-lactamases and 65 Acinetobacter-derived cephalosporinases in Acinetobacter spp.

Périchon B, Goussard S, Walewski V, Krizova L, Cerqueira G, Murphy C, Feldgarden M, Wortman J, Clermont D, Nemec A, Courvalin P.

Antimicrob Agents Chemother. 2014;58(2):936-49. doi: 10.1128/AAC.01261-13. Epub 2013 Nov 25.


Emergence of colistin-resistance in extremely drug-resistant Acinetobacter baumannii containing a novel pmrCAB operon during colistin therapy of wound infections.

Lesho E, Yoon EJ, McGann P, Snesrud E, Kwak Y, Milillo M, Onmus-Leone F, Preston L, St Clair K, Nikolich M, Viscount H, Wortmann G, Zapor M, Grillot-Courvalin C, Courvalin P, Clifford R, Waterman PE.

J Infect Dis. 2013 Oct 1;208(7):1142-51. doi: 10.1093/infdis/jit293. Epub 2013 Jun 28.


The functional vanGCd cluster of Clostridium difficile does not confer vancomycin resistance.

Ammam F, Meziane-Cherif D, Mengin-Lecreulx D, Blanot D, Patin D, Boneca IG, Courvalin P, Lambert T, Candela T.

Mol Microbiol. 2013 Aug;89(4):612-25. doi: 10.1111/mmi.12299. Epub 2013 Jul 12.


RND-type efflux pumps in multidrug-resistant clinical isolates of Acinetobacter baumannii: major role for AdeABC overexpression and AdeRS mutations.

Yoon EJ, Courvalin P, Grillot-Courvalin C.

Antimicrob Agents Chemother. 2013 Jul;57(7):2989-95. doi: 10.1128/AAC.02556-12. Epub 2013 Apr 15.


Structural and functional characterization of VanG D-Ala:D-Ser ligase associated with vancomycin resistance in Enterococcus faecalis.

Meziane-Cherif D, Saul FA, Haouz A, Courvalin P.

J Biol Chem. 2012 Nov 2;287(45):37583-92. doi: 10.1074/jbc.M112.405522. Epub 2012 Sep 11.


Staphylococcus aureus VRSA-11B is a constitutive vancomycin-resistant mutant of vancomycin-dependent VRSA-11A.

Périchon B, Courvalin P.

Antimicrob Agents Chemother. 2012 Sep;56(9):4693-6. doi: 10.1128/AAC.00454-12. Epub 2012 Jun 18.


RmtF, a new member of the aminoglycoside resistance 16S rRNA N7 G1405 methyltransferase family.

Galimand M, Courvalin P, Lambert T.

Antimicrob Agents Chemother. 2012 Jul;56(7):3960-2. doi: 10.1128/AAC.00660-12. Epub 2012 Apr 30.


Expression of the resistance-nodulation-cell division pump AdeIJK in Acinetobacter baumannii is regulated by AdeN, a TetR-type regulator.

Rosenfeld N, Bouchier C, Courvalin P, Périchon B.

Antimicrob Agents Chemother. 2012 May;56(5):2504-10. doi: 10.1128/AAC.06422-11. Epub 2012 Feb 27.


Tackling antibiotic resistance.

Bush K, Courvalin P, Dantas G, Davies J, Eisenstein B, Huovinen P, Jacoby GA, Kishony R, Kreiswirth BN, Kutter E, Lerner SA, Levy S, Lewis K, Lomovskaya O, Miller JH, Mobashery S, Piddock LJ, Projan S, Thomas CM, Tomasz A, Tulkens PM, Walsh TR, Watson JD, Witkowski J, Witte W, Wright G, Yeh P, Zgurskaya HI.

Nat Rev Microbiol. 2011 Nov 2;9(12):894-6. doi: 10.1038/nrmicro2693. Review.


D-Ala-d-Ser VanN-type transferable vancomycin resistance in Enterococcus faecium.

Lebreton F, Depardieu F, Bourdon N, Fines-Guyon M, Berger P, Camiade S, Leclercq R, Courvalin P, Cattoir V.

Antimicrob Agents Chemother. 2011 Oct;55(10):4606-12. doi: 10.1128/AAC.00714-11. Epub 2011 Aug 1.


Expert systems in clinical microbiology.

Winstanley T, Courvalin P.

Clin Microbiol Rev. 2011 Jul;24(3):515-56. doi: 10.1128/CMR.00061-10. Review.


Ceftazidime-hydrolysing β-lactamase OXA-145 with impaired hydrolysis of penicillins in Pseudomonas aeruginosa.

Hocquet D, Colomb M, Dehecq B, Belmonte O, Courvalin P, Plésiat P, Meziane-Cherif D.

J Antimicrob Chemother. 2011 Aug;66(8):1745-50. doi: 10.1093/jac/dkr187. Epub 2011 Jun 10.


Antimicrobial resistance of Listeria monocytogenes isolates from food and the environment in France over a 10-year period.

Granier SA, Moubareck C, Colaneri C, Lemire A, Roussel S, Dao TT, Courvalin P, Brisabois A.

Appl Environ Microbiol. 2011 Apr;77(8):2788-90. doi: 10.1128/AEM.01381-10. Epub 2011 Feb 25.


Plasmid-mediated quinolone resistance in expanded spectrum beta lactamase producing enterobacteriaceae in Morocco.

Bouchakour M, Zerouali K, Gros Claude JD, Amarouch H, El Mdaghri N, Courvalin P, Timinouni M.

J Infect Dev Ctries. 2010 Dec 23;4(12):779-803.


Efflux-mediated antibiotic resistance in Acinetobacter spp.

Coyne S, Courvalin P, Périchon B.

Antimicrob Agents Chemother. 2011 Mar;55(3):947-53. doi: 10.1128/AAC.01388-10. Epub 2010 Dec 20. Review.

Supplemental Content

Loading ...
Support Center