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Items: 1 to 50 of 68

1.

Publisher Correction: Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics.

Carreras-Sureda A, Jaña F, Urra H, Durand S, Mortenson DE, Sagredo A, Bustos G, Hazari Y, Ramos-Fernández E, Sassano ML, Pihán P, van Vliet AR, González-Quiroz M, Torres AK, Tapia-Rojas C, Kerkhofs M, Vicente R, Kaufman RJ, Inestrosa NC, Gonzalez-Billault C, Wiseman RL, Agostinis P, Bultynck G, Court FA, Kroemer G, Cárdenas JC, Hetz C.

Nat Cell Biol. 2019 Jul;21(7):913. doi: 10.1038/s41556-019-0355-9.

PMID:
31201389
2.

Altered mitochondrial bioenergetics are responsible for the delay in Wallerian degeneration observed in neonatal mice.

Kline RA, Dissanayake KN, Hurtado ML, Martínez NW, Ahl A, Mole AJ, Lamont DJ, Court FA, Ribchester RR, Wishart TM, Murray LM.

Neurobiol Dis. 2019 Jun 6;130:104496. doi: 10.1016/j.nbd.2019.104496. [Epub ahead of print]

3.

Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics.

Carreras-Sureda A, Jaña F, Urra H, Durand S, Mortenson DE, Sagredo A, Bustos G, Hazari Y, Ramos-Fernández E, Sassano ML, Pihán P, van Vliet AR, González-Quiroz M, Torres AK, Tapia-Rojas C, Kerkhofs M, Vicente R, Kaufman RJ, Inestrosa NC, Gonzalez-Billault C, Wiseman RL, Agostinis P, Bultynck G, Court FA, Kroemer G, Cárdenas JC, Hetz C.

Nat Cell Biol. 2019 Jun;21(6):755-767. doi: 10.1038/s41556-019-0329-y. Epub 2019 May 20. Erratum in: Nat Cell Biol. 2019 Jun 14;:.

PMID:
31110288
4.

c-Jun N-terminal kinase (JNK)-dependent internalization and Rab5-dependent endocytic sorting mediate long-distance retrograde neuronal death induced by axonal BDNF-p75 signaling.

Escudero CA, Cabeza C, Moya-Alvarado G, Maloney MT, Flores CM, Wu C, Court FA, Mobley WC, Bronfman FC.

Sci Rep. 2019 Apr 15;9(1):6070. doi: 10.1038/s41598-019-42420-6.

5.

Compartmentalized necroptosis activation in excitotoxicity-induced axonal degeneration: a novel mechanism implicated in neurodegenerative disease pathology.

Arrazola MS, Court FA.

Neural Regen Res. 2019 Aug;14(8):1385-1386. doi: 10.4103/1673-5374.253520. No abstract available.

6.

Axonal Degeneration Is Mediated by Necroptosis Activation.

Arrázola MS, Saquel C, Catalán RJ, Barrientos SA, Hernandez DE, Martínez NW, Catenaccio A, Court FA.

J Neurosci. 2019 May 15;39(20):3832-3844. doi: 10.1523/JNEUROSCI.0881-18.2019. Epub 2019 Mar 8.

PMID:
30850513
7.

Axonal degeneration induced by glutamate excitotoxicity is mediated by necroptosis.

Hernández DE, Salvadores NA, Moya-Alvarado G, Catalán RJ, Bronfman FC, Court FA.

J Cell Sci. 2018 Nov 19;131(22). pii: jcs214684. doi: 10.1242/jcs.214684.

8.

Publisher Correction: IRE1α governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A.

Urra H, Henriquez DR, Cánovas J, Villarroel-Campos D, Carreras-Sureda A, Pulgar E, Molina E, Hazari YM, Limia CM, Alvarez-Rojas S, Figueroa R, Vidal RL, Rodriguez DA, Rivera CA, Court FA, Couve A, Qi L, Chevet E, Akai R, Iwawaki T, Concha ML, Glavic Á, Gonzalez-Billault C, Hetz C.

Nat Cell Biol. 2018 Oct;20(10):1228. doi: 10.1038/s41556-018-0186-0.

PMID:
30089843
9.

Mitochondria and Calcium Regulation as Basis of Neurodegeneration Associated With Aging.

Müller M, Ahumada-Castro U, Sanhueza M, Gonzalez-Billault C, Court FA, Cárdenas C.

Front Neurosci. 2018 Jul 13;12:470. doi: 10.3389/fnins.2018.00470. eCollection 2018.

10.

IRE1α governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A.

Urra H, Henriquez DR, Cánovas J, Villarroel-Campos D, Carreras-Sureda A, Pulgar E, Molina E, Hazari YM, Limia CM, Alvarez-Rojas S, Figueroa R, Vidal RL, Rodriguez DA, Rivera CA, Court FA, Couve A, Qi L, Chevet E, Akai R, Iwawaki T, Concha ML, Glavic Á, Gonzalez-Billault C, Hetz C.

Nat Cell Biol. 2018 Aug;20(8):942-953. doi: 10.1038/s41556-018-0141-0. Epub 2018 Jul 16. Erratum in: Nat Cell Biol. 2018 Oct;20(10):1228.

PMID:
30013108
11.

The inhibition of CTGF/CCN2 activity improves muscle and locomotor function in a murine ALS model.

Gonzalez D, Rebolledo DL, Correa LM, Court FA, Cerpa W, Lipson KE, van Zundert B, Brandan E.

Hum Mol Genet. 2018 Aug 15;27(16):2913-2926. doi: 10.1093/hmg/ddy204.

PMID:
29860398
12.

Teased Fiber Preparation of Myelinated Nerve Fibers from Peripheral Nerves for Vital Dye Staining and Immunofluorescence Analysis.

Catenaccio A, Court FA.

Methods Mol Biol. 2018;1739:329-337. doi: 10.1007/978-1-4939-7649-2_21.

PMID:
29546717
13.

Purification of Exosomes from Primary Schwann Cells, RNA Extraction, and Next-Generation Sequencing of Exosomal RNAs.

De Gregorio C, Díaz P, López-Leal R, Manque P, Court FA.

Methods Mol Biol. 2018;1739:299-315. doi: 10.1007/978-1-4939-7649-2_19.

PMID:
29546715
14.

In Vitro Analysis of the Role of Schwann Cells on Axonal Degeneration and Regeneration Using Sensory Neurons from Dorsal Root Ganglia.

López-Leal R, Diaz P, Court FA.

Methods Mol Biol. 2018;1739:255-267. doi: 10.1007/978-1-4939-7649-2_16.

PMID:
29546712
15.

A dual role for Integrin α6β4 in modulating hereditary neuropathy with liability to pressure palsies.

Poitelon Y, Matafora V, Silvestri N, Zambroni D, McGarry C, Serghany N, Rush T, Vizzuso D, Court FA, Bachi A, Wrabetz L, Feltri ML.

J Neurochem. 2018 May;145(3):245-257. doi: 10.1111/jnc.14295. Epub 2018 Feb 13.

16.

Molecular analysis of axonal-intrinsic and glial-associated co-regulation of axon degeneration.

Catenaccio A, Llavero Hurtado M, Diaz P, Lamont DJ, Wishart TM, Court FA.

Cell Death Dis. 2017 Nov 9;8(11):e3166. doi: 10.1038/cddis.2017.489.

17.

Disulfide cross-linked multimers of TDP-43 and spinal motoneuron loss in a TDP-43A315T ALS/FTD mouse model.

Bargsted L, Medinas DB, Martínez Traub F, Rozas P, Muñoz N, Nassif M, Jerez C, Catenaccio A, Court FA, Hetz C, Matus S.

Sci Rep. 2017 Oct 27;7(1):14266. doi: 10.1038/s41598-017-14399-5.

18.

Axonal Degeneration during Aging and Its Functional Role in Neurodegenerative Disorders.

Salvadores N, Sanhueza M, Manque P, Court FA.

Front Neurosci. 2017 Sep 4;11:451. doi: 10.3389/fnins.2017.00451. eCollection 2017. Review.

19.

Herpes Simplex Virus Type 1 Neuronal Infection Perturbs Golgi Apparatus Integrity through Activation of Src Tyrosine Kinase and Dyn-2 GTPase.

Martin C, Leyton L, Hott M, Arancibia Y, Spichiger C, McNiven MA, Court FA, Concha MI, Burgos PV, Otth C.

Front Cell Infect Microbiol. 2017 Aug 22;7:371. doi: 10.3389/fcimb.2017.00371. eCollection 2017.

20.

BAX inhibitor-1 regulates autophagy by controlling the IRE1α branch of the unfolded protein response.

Castillo K, Rojas-Rivera D, Lisbona F, Caballero B, Nassif M, Court FA, Schuck S, Ibar C, Walter P, Sierralta J, Glavic A, Hetz C.

EMBO J. 2017 Jun 1;36(11):1640. doi: 10.15252/embj.201797020. No abstract available.

21.

Origin of axonal proteins: Is the axon-schwann cell unit a functional syncytium?

López-Leal R, Alvarez J, Court FA.

Cytoskeleton (Hoboken). 2016 Oct;73(10):629-639. doi: 10.1002/cm.21319. Epub 2016 Sep 10. Review.

PMID:
27490284
22.

Schwann Cell and Axon: An Interlaced Unit-From Action Potential to Phenotype Expression.

Court FA, Alvarez J.

Adv Exp Med Biol. 2016;949:183-201. Review.

PMID:
27714690
23.

Corrigendum: Microtubule-associated protein 1B (MAP1B)-deficient neurons show structural presynaptic deficiencies in vitro and altered presynaptic physiology.

Bodaleo FJ, Montenegro-Venegas C, Henríquez DR, Court FA, Gonzalez-Billault C.

Sci Rep. 2016 Sep 2;6:32275. doi: 10.1038/srep32275. No abstract available.

24.

Bursting the unfolded protein response accelerates axonal regeneration.

Oñate M, Court FA, Hetz C.

Neural Regen Res. 2016 Jun;11(6):892-3. doi: 10.4103/1673-5374.184453. No abstract available.

25.

Microtubule-associated protein 1B (MAP1B)-deficient neurons show structural presynaptic deficiencies in vitro and altered presynaptic physiology.

Bodaleo FJ, Montenegro-Venegas C, Henríquez DR, Court FA, Gonzalez-Billault C.

Sci Rep. 2016 Jul 18;6:30069. doi: 10.1038/srep30069. Erratum in: Sci Rep. 2016 Sep 02;6:32275.

26.

Injury to the nervous system: A look into the ER.

Valenzuela V, Oñate M, Hetz C, Court FA.

Brain Res. 2016 Oct 1;1648(Pt B):617-625. doi: 10.1016/j.brainres.2016.04.053. Epub 2016 Apr 23. Review.

PMID:
27117870
27.

Corrigendum to "ApoER2 and reelin are expressed in regenerating peripheral nerve and regulate Schwann cell migration by activating the Rac1 GEF protein, Tiam1"[Mol Cell Neurosci 69C (2015) 1-11].

Pasten C, Cerda J, Jausoro I, Court FA, Cáceres A, Marzolo MP.

Mol Cell Neurosci. 2016 Apr;72:123. doi: 10.1016/j.mcn.2016.03.002. Epub 2016 Mar 17. No abstract available.

PMID:
27040664
28.

Altered potassium channel distribution and composition in myelinated axons suppresses hyperexcitability following injury.

Calvo M, Richards N, Schmid AB, Barroso A, Zhu L, Ivulic D, Zhu N, Anwandter P, Bhat MA, Court FA, McMahon SB, Bennett DL.

Elife. 2016 Apr 19;5:e12661. doi: 10.7554/eLife.12661.

29.

Schwann Cell Exosomes Mediate Neuron-Glia Communication and Enhance Axonal Regeneration.

Lopez-Leal R, Court FA.

Cell Mol Neurobiol. 2016 Apr;36(3):429-36. doi: 10.1007/s10571-015-0314-3. Epub 2016 Mar 18. Review.

PMID:
26993502
30.

Activation of the unfolded protein response promotes axonal regeneration after peripheral nerve injury.

Oñate M, Catenaccio A, Martínez G, Armentano D, Parsons G, Kerr B, Hetz C, Court FA.

Sci Rep. 2016 Feb 24;6:21709. doi: 10.1038/srep21709.

31.

Axons provide the secretory machinery for trafficking of voltage-gated sodium channels in peripheral nerve.

González C, Cánovas J, Fresno J, Couve E, Court FA, Couve A.

Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):1823-8. doi: 10.1073/pnas.1514943113. Epub 2016 Feb 2.

32.

Applying extracellular vesicles based therapeutics in clinical trials - an ISEV position paper.

Lener T, Gimona M, Aigner L, Börger V, Buzas E, Camussi G, Chaput N, Chatterjee D, Court FA, Del Portillo HA, O'Driscoll L, Fais S, Falcon-Perez JM, Felderhoff-Mueser U, Fraile L, Gho YS, Görgens A, Gupta RC, Hendrix A, Hermann DM, Hill AF, Hochberg F, Horn PA, de Kleijn D, Kordelas L, Kramer BW, Krämer-Albers EM, Laner-Plamberger S, Laitinen S, Leonardi T, Lorenowicz MJ, Lim SK, Lötvall J, Maguire CA, Marcilla A, Nazarenko I, Ochiya T, Patel T, Pedersen S, Pocsfalvi G, Pluchino S, Quesenberry P, Reischl IG, Rivera FJ, Sanzenbacher R, Schallmoser K, Slaper-Cortenbach I, Strunk D, Tonn T, Vader P, van Balkom BW, Wauben M, Andaloussi SE, Théry C, Rohde E, Giebel B.

J Extracell Vesicles. 2015 Dec 31;4:30087. doi: 10.3402/jev.v4.30087. eCollection 2015.

33.

Correction: Functional Role of the Disulfide Isomerase ERp57 in Axonal Regeneration.

Castillo V, Oñate M, Woehlbier U, Rozas P, Andreu C, Medinas D, Valdés P, Osorio F, Mercado G, Vidal RL, Kerr B, Court FA, Hetz C.

PLoS One. 2015 Oct 2;10(10):e0140200. doi: 10.1371/journal.pone.0140200. eCollection 2015. No abstract available.

34.

ApoER2 and Reelin are expressed in regenerating peripheral nerve and regulate Schwann cell migration by activating the Rac1 GEF protein, Tiam1.

Pasten C, Cerda J, Jausoro I, Court FA, Cáceres A, Marzolo MP.

Mol Cell Neurosci. 2015 Nov;69:1-11. doi: 10.1016/j.mcn.2015.09.004. Epub 2015 Sep 16. Erratum in: Mol Cell Neurosci. 2016 Apr;72:123.

PMID:
26386179
35.

Functional Role of the Disulfide Isomerase ERp57 in Axonal Regeneration.

Castillo V, Oñate M, Woehlbier U, Rozas P, Andreu C, Medinas D, Valdés P, Osorio F, Mercado G, Vidal RL, Kerr B, Court FA, Hetz C.

PLoS One. 2015 Sep 11;10(9):e0136620. doi: 10.1371/journal.pone.0136620. eCollection 2015. Erratum in: PLoS One. 2015;10(10):e0140200.

36.

Emerging roles of extracellular vesicles in the nervous system.

Rajendran L, Bali J, Barr MM, Court FA, Krämer-Albers EM, Picou F, Raposo G, van der Vos KE, van Niel G, Wang J, Breakefield XO.

J Neurosci. 2014 Nov 12;34(46):15482-9. doi: 10.1523/JNEUROSCI.3258-14.2014. Review.

37.

Sprouting of axonal collaterals after spinal cord injury is prevented by delayed axonal degeneration.

Collyer E, Catenaccio A, Lemaitre D, Diaz P, Valenzuela V, Bronfman F, Court FA.

Exp Neurol. 2014 Nov;261:451-61. doi: 10.1016/j.expneurol.2014.07.014. Epub 2014 Jul 28.

PMID:
25079366
38.

Calcium release from intra-axonal endoplasmic reticulum leads to axon degeneration through mitochondrial dysfunction.

Villegas R, Martinez NW, Lillo J, Pihan P, Hernandez D, Twiss JL, Court FA.

J Neurosci. 2014 May 21;34(21):7179-89. doi: 10.1523/JNEUROSCI.4784-13.2014.

39.

Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1.

Valdés P, Mercado G, Vidal RL, Molina C, Parsons G, Court FA, Martinez A, Galleguillos D, Armentano D, Schneider BL, Hetz C.

Proc Natl Acad Sci U S A. 2014 May 6;111(18):6804-9. doi: 10.1073/pnas.1321845111. Epub 2014 Apr 21.

40.

The p75 neurotrophin receptor evades the endolysosomal route in neuronal cells, favouring multivesicular bodies specialised for exosomal release.

Escudero CA, Lazo OM, Galleguillos C, Parraguez JI, Lopez-Verrilli MA, Cabeza C, Leon L, Saeed U, Retamal C, Gonzalez A, Marzolo MP, Carter BD, Court FA, Bronfman FC.

J Cell Sci. 2014 May 1;127(Pt 9):1966-79. doi: 10.1242/jcs.141754. Epub 2014 Feb 25.

41.

Measurement of autophagy flux in the nervous system in vivo.

Castillo K, Valenzuela V, Matus S, Nassif M, Oñate M, Fuentealba Y, Encina G, Irrazabal T, Parsons G, Court FA, Schneider BL, Armentano D, Hetz C.

Cell Death Dis. 2013 Nov 14;4:e917. doi: 10.1038/cddis.2013.421.

42.

Schwann cell-derived exosomes enhance axonal regeneration in the peripheral nervous system.

Lopez-Verrilli MA, Picou F, Court FA.

Glia. 2013 Nov;61(11):1795-806. doi: 10.1002/glia.22558. Epub 2013 Aug 30.

PMID:
24038411
43.

Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons.

Castillo K, Nassif M, Valenzuela V, Rojas F, Matus S, Mercado G, Court FA, van Zundert B, Hetz C.

Autophagy. 2013 Sep;9(9):1308-20. doi: 10.4161/auto.25188. Epub 2013 Jun 6.

PMID:
23851366
44.

Exosomes: mediators of communication in eukaryotes.

Lopez-Verrilli MA, Court FA.

Biol Res. 2013;46(1):5-11. doi: 10.4067/S0716-97602013000100001. Review.

45.

Diapause formation and downregulation of insulin-like signaling via DAF-16/FOXO delays axonal degeneration and neuronal loss.

Calixto A, Jara JS, Court FA.

PLoS Genet. 2012;8(12):e1003141. doi: 10.1371/journal.pgen.1003141. Epub 2012 Dec 27.

46.

A BAX/BAK and cyclophilin D-independent intrinsic apoptosis pathway.

Zamorano S, Rojas-Rivera D, Lisbona F, Parra V, Court FA, Villegas R, Cheng EH, Korsmeyer SJ, Lavandero S, Hetz C.

PLoS One. 2012;7(6):e37782. doi: 10.1371/journal.pone.0037782. Epub 2012 Jun 12.

47.

Transfer of vesicles from schwann cells to axons: a novel mechanism of communication in the peripheral nervous system.

Lopez-Verrilli MA, Court FA.

Front Physiol. 2012 Jun 13;3:205. doi: 10.3389/fphys.2012.00205. eCollection 2012.

48.

Mitochondria as a central sensor for axonal degenerative stimuli.

Court FA, Coleman MP.

Trends Neurosci. 2012 Jun;35(6):364-72. doi: 10.1016/j.tins.2012.04.001. Epub 2012 May 11. Review.

PMID:
22578891
49.

Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy.

Vidal RL, Figueroa A, Court FA, Thielen P, Molina C, Wirth C, Caballero B, Kiffin R, Segura-Aguilar J, Cuervo AM, Glimcher LH, Hetz C.

Hum Mol Genet. 2012 May 15;21(10):2245-62. doi: 10.1093/hmg/dds040. Epub 2012 Feb 14.

50.

Activation of the unfolded protein response enhances motor recovery after spinal cord injury.

Valenzuela V, Collyer E, Armentano D, Parsons GB, Court FA, Hetz C.

Cell Death Dis. 2012 Feb 16;3:e272. doi: 10.1038/cddis.2012.8.

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