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Items: 35

1.

Sex Differences in Circulating Biomarkers of Cardiovascular Disease.

Lau ES, Paniagua SM, Guseh JS, Bhambhani V, Zanni MV, Courchesne P, Lyass A, Larson MG, Levy D, Ho JE.

J Am Coll Cardiol. 2019 Sep 24;74(12):1543-1553. doi: 10.1016/j.jacc.2019.06.077.

PMID:
31537263
2.

Circulating IGFBP-2: a novel biomarker for incident dementia.

McGrath ER, Himali JJ, Levy D, Conner SC, DeCarli CS, Pase MP, Courchesne P, Satizabal CL, Vasan RS, Beiser AS, Seshadri S.

Ann Clin Transl Neurol. 2019 Sep;6(9):1659-1670. doi: 10.1002/acn3.50854. Epub 2019 Aug 2.

3.

Epigenome-wide association study of DNA methylation and microRNA expression highlights novel pathways for human complex traits.

Huan T, Mendelson M, Joehanes R, Yao C, Liu C, Song C, Bhattacharya A, Rong J, Tanriverdi K, Keefe J, Murabito JM, Courchesne P, Larson MG, Freedman JE, Levy D.

Epigenetics. 2019 Jul 17:1-16. doi: 10.1080/15592294.2019.1640547. [Epub ahead of print]

PMID:
31282290
4.

Circulating fibroblast growth factor 23 levels and incident dementia: The Framingham heart study.

McGrath ER, Himali JJ, Levy D, Conner SC, Pase MP, Abraham CR, Courchesne P, Satizabal CL, Vasan RS, Beiser AS, Seshadri S.

PLoS One. 2019 Mar 4;14(3):e0213321. doi: 10.1371/journal.pone.0213321. eCollection 2019.

5.

Evidence for a Causal Role of the SH2B3-β2M Axis in Blood Pressure Regulation.

Keefe JA, Hwang SJ, Huan T, Mendelson M, Yao C, Courchesne P, Saleh MA, Madhur MS, Levy D.

Hypertension. 2019 Feb;73(2):497-503. doi: 10.1161/HYPERTENSIONAHA.118.12094.

PMID:
30624993
6.

Author Correction: Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease.

Yao C, Chen G, Song C, Keefe J, Mendelson M, Huan T, Sun BB, Laser A, Maranville JC, Wu H, Ho JE, Courchesne P, Lyass A, Larson MG, Gieger C, Graumann J, Johnson AD, Danesh J, Runz H, Hwang SJ, Liu C, Butterworth AS, Suhre K, Levy D.

Nat Commun. 2018 Sep 18;9(1):3853. doi: 10.1038/s41467-018-06231-z.

7.

Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease.

Yao C, Chen G, Song C, Keefe J, Mendelson M, Huan T, Sun BB, Laser A, Maranville JC, Wu H, Ho JE, Courchesne P, Lyass A, Larson MG, Gieger C, Graumann J, Johnson AD, Danesh J, Runz H, Hwang SJ, Liu C, Butterworth AS, Suhre K, Levy D.

Nat Commun. 2018 Aug 15;9(1):3268. doi: 10.1038/s41467-018-05512-x. Erratum in: Nat Commun. 2018 Sep 18;9(1):3853.

8.

Protein Biomarkers of Cardiovascular Disease and Mortality in the Community.

Ho JE, Lyass A, Courchesne P, Chen G, Liu C, Yin X, Hwang SJ, Massaro JM, Larson MG, Levy D.

J Am Heart Assoc. 2018 Jul 13;7(14). pii: e008108. doi: 10.1161/JAHA.117.008108.

9.

MicroRNA Signature of Cigarette Smoking and Evidence for a Putative Causal Role of MicroRNAs in Smoking-Related Inflammation and Target Organ Damage.

Willinger CM, Rong J, Tanriverdi K, Courchesne PL, Huan T, Wasserman GA, Lin H, Dupuis J, Joehanes R, Jones MR, Chen G, Benjamin EJ, O'Connor GT, Mizgerd JP, Freedman JE, Larson MG, Levy D.

Circ Cardiovasc Genet. 2017 Oct;10(5). pii: e001678. doi: 10.1161/CIRCGENETICS.116.001678.

10.

Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach.

Mendelson MM, Marioni RE, Joehanes R, Liu C, Hedman ÅK, Aslibekyan S, Demerath EW, Guan W, Zhi D, Yao C, Huan T, Willinger C, Chen B, Courchesne P, Multhaup M, Irvin MR, Cohain A, Schadt EE, Grove ML, Bressler J, North K, Sundström J, Gustafsson S, Shah S, McRae AF, Harris SE, Gibson J, Redmond P, Corley J, Murphy L, Starr JM, Kleinbrink E, Lipovich L, Visscher PM, Wray NR, Krauss RM, Fallin D, Feinberg A, Absher DM, Fornage M, Pankow JS, Lind L, Fox C, Ingelsson E, Arnett DK, Boerwinkle E, Liang L, Levy D, Deary IJ.

PLoS Med. 2017 Jan 17;14(1):e1002215. doi: 10.1371/journal.pmed.1002215. eCollection 2017 Jan.

11.

Plasma clusterin levels and risk of dementia, Alzheimer's disease, and stroke.

Weinstein G, Beiser AS, Preis SR, Courchesne P, Chouraki V, Levy D, Seshadri S.

Alzheimers Dement (Amst). 2016 Jul 9;3:103-9. doi: 10.1016/j.dadm.2016.06.005. eCollection 2016.

12.

Metabolite Signatures of Metabolic Risk Factors and their Longitudinal Changes.

Yin X, Subramanian S, Willinger CM, Chen G, Juhasz P, Courchesne P, Chen BH, Li X, Hwang SJ, Fox CS, O'Donnell CJ, Muntendam P, Fuster V, Bobeldijk-Pastorova I, Sookoian SC, Pirola CJ, Gordon N, Adourian A, Larson MG, Levy D.

J Clin Endocrinol Metab. 2016 Apr;101(4):1779-89. doi: 10.1210/jc.2015-2555. Epub 2016 Feb 23.

13.

Integrative network analysis reveals molecular mechanisms of blood pressure regulation.

Huan T, Meng Q, Saleh MA, Norlander AE, Joehanes R, Zhu J, Chen BH, Zhang B, Johnson AD, Ying S, Courchesne P, Raghavachari N, Wang R, Liu P; International Consortium for Blood Pressure GWAS (ICBP), O'Donnell CJ, Vasan R, Munson PJ, Madhur MS, Harrison DG, Yang X, Levy D.

Mol Syst Biol. 2015 Apr 16;11(1):799. doi: 10.15252/msb.20145399.

14.

Genome-wide identification of microRNA expression quantitative trait loci.

Huan T, Rong J, Liu C, Zhang X, Tanriverdi K, Joehanes R, Chen BH, Murabito JM, Yao C, Courchesne P, Munson PJ, O'Donnell CJ, Cox N, Johnson AD, Larson MG, Levy D, Freedman JE.

Nat Commun. 2015 Mar 20;6:6601. doi: 10.1038/ncomms7601.

15.

A meta-analysis of gene expression signatures of blood pressure and hypertension.

Huan T, Esko T, Peters MJ, Pilling LC, Schramm K, Schurmann C, Chen BH, Liu C, Joehanes R, Johnson AD, Yao C, Ying SX, Courchesne P, Milani L, Raghavachari N, Wang R, Liu P, Reinmaa E, Dehghan A, Hofman A, Uitterlinden AG, Hernandez DG, Bandinelli S, Singleton A, Melzer D, Metspalu A, Carstensen M, Grallert H, Herder C, Meitinger T, Peters A, Roden M, Waldenberger M, Dörr M, Felix SB, Zeller T; International Consortium for Blood Pressure GWAS (ICBP), Vasan R, O'Donnell CJ, Munson PJ, Yang X, Prokisch H, Völker U, van Meurs JB, Ferrucci L, Levy D.

PLoS Genet. 2015 Mar 18;11(3):e1005035. doi: 10.1371/journal.pgen.1005035. eCollection 2015 Mar.

16.

Dissecting the roles of microRNAs in coronary heart disease via integrative genomic analyses.

Huan T, Rong J, Tanriverdi K, Meng Q, Bhattacharya A, McManus DD, Joehanes R, Assimes TL, McPherson R, Samani NJ, Erdmann J, Schunkert H, Courchesne P, Munson PJ, Johnson AD, O'Donnell CJ, Zhang B, Larson MG, Freedman JE, Levy D, Yang X.

Arterioscler Thromb Vasc Biol. 2015 Apr;35(4):1011-21. doi: 10.1161/ATVBAHA.114.305176. Epub 2015 Feb 5.

17.

A systematic heritability analysis of the human whole blood transcriptome.

Huan T, Liu C, Joehanes R, Zhang X, Chen BH, Johnson AD, Yao C, Courchesne P, O'Donnell CJ, Munson PJ, Levy D.

Hum Genet. 2015 Mar;134(3):343-58. doi: 10.1007/s00439-014-1524-3. Epub 2015 Jan 14.

18.

Integromic analysis of genetic variation and gene expression identifies networks for cardiovascular disease phenotypes.

Yao C, Chen BH, Joehanes R, Otlu B, Zhang X, Liu C, Huan T, Tastan O, Cupples LA, Meigs JB, Fox CS, Freedman JE, Courchesne P, O'Donnell CJ, Munson PJ, Keles S, Levy D.

Circulation. 2015 Feb 10;131(6):536-49. doi: 10.1161/CIRCULATIONAHA.114.010696. Epub 2014 Dec 22. Erratum in: Circulation. 2015 May 12;131(19):e474.

19.

Stromal cell-derived factor 1 as a biomarker of heart failure and mortality risk.

Subramanian S, Liu C, Aviv A, Ho JE, Courchesne P, Muntendam P, Larson MG, Cheng S, Wang TJ, Mehta NN, Levy D.

Arterioscler Thromb Vasc Biol. 2014 Sep;34(9):2100-5. doi: 10.1161/ATVBAHA.114.303579. Epub 2014 Jul 24.

20.

Protein biomarkers of new-onset cardiovascular disease: prospective study from the systems approach to biomarker research in cardiovascular disease initiative.

Yin X, Subramanian S, Hwang SJ, O'Donnell CJ, Fox CS, Courchesne P, Muntendam P, Gordon N, Adourian A, Juhasz P, Larson MG, Levy D.

Arterioscler Thromb Vasc Biol. 2014 Apr;34(4):939-45. doi: 10.1161/ATVBAHA.113.302918. Epub 2014 Feb 13.

21.

Gene expression signatures of coronary heart disease.

Joehanes R, Ying S, Huan T, Johnson AD, Raghavachari N, Wang R, Liu P, Woodhouse KA, Sen SK, Tanriverdi K, Courchesne P, Freedman JE, O'Donnell CJ, Levy D, Munson PJ.

Arterioscler Thromb Vasc Biol. 2013 Jun;33(6):1418-26. doi: 10.1161/ATVBAHA.112.301169. Epub 2013 Mar 28.

22.

A systems biology framework identifies molecular underpinnings of coronary heart disease.

Huan T, Zhang B, Wang Z, Joehanes R, Zhu J, Johnson AD, Ying S, Munson PJ, Raghavachari N, Wang R, Liu P, Courchesne P, Hwang SJ, Assimes TL, McPherson R, Samani NJ, Schunkert H; Coronary ARteryDIsease Genome wide Replication and Meta-analysis (CARDIoGRAM) Consortium, International Consortium for Blood Pressure GWAS (ICBP), Meng Q, Suver C, O'Donnell CJ, Derry J, Yang X, Levy D.

Arterioscler Thromb Vasc Biol. 2013 Jun;33(6):1427-34. doi: 10.1161/ATVBAHA.112.300112. Epub 2013 Mar 28.

23.

Galectin-3, a marker of cardiac fibrosis, predicts incident heart failure in the community.

Ho JE, Liu C, Lyass A, Courchesne P, Pencina MJ, Vasan RS, Larson MG, Levy D.

J Am Coll Cardiol. 2012 Oct 2;60(14):1249-56. doi: 10.1016/j.jacc.2012.04.053. Epub 2012 Aug 29.

24.

The liver toxicity biomarker study phase I: markers for the effects of tolcapone or entacapone.

McBurney RN, Hines WM, VonTungeln LS, Schnackenberg LK, Beger RD, Moland CL, Han T, Fuscoe JC, Chang CW, Chen JJ, Su Z, Fan XH, Tong W, Booth SA, Balasubramanian R, Courchesne PL, Campbell JM, Graber A, Guo Y, Juhasz P, Li TY, Lynch MD, Morel NM, Plasterer TN, Takach EJ, Zeng C, Beland FA.

Toxicol Pathol. 2012 Aug;40(6):951-64. doi: 10.1177/0192623312444026. Epub 2012 May 9.

PMID:
22573522
25.

The liver toxicity biomarker study: phase I design and preliminary results.

McBurney RN, Hines WM, Von Tungeln LS, Schnackenberg LK, Beger RD, Moland CL, Han T, Fuscoe JC, Chang CW, Chen JJ, Su Z, Fan XH, Tong W, Booth SA, Balasubramanian R, Courchesne PL, Campbell JM, Graber A, Guo Y, Juhasz PJ, Li TY, Lynch MD, Morel NM, Plasterer TN, Takach EJ, Zeng C, Beland FA.

Toxicol Pathol. 2009 Jan;37(1):52-64. doi: 10.1177/0192623308329287. Epub 2009 Jan 26.

PMID:
19171931
26.

Towards defining the urinary proteome using liquid chromatography-tandem mass spectrometry. I. Profiling an unfractionated tryptic digest.

Spahr CS, Davis MT, McGinley MD, Robinson JH, Bures EJ, Beierle J, Mort J, Courchesne PL, Chen K, Wahl RC, Yu W, Luethy R, Patterson SD.

Proteomics. 2001 Jan;1(1):93-107.

PMID:
11680902
27.

Identification of incompletely processed potential carboxypeptidase E substrates from CpEfat/CpEfat mice.

Bures EJ, Courchesne PL, Douglass J, Chen K, Davis MT, Jones MD, McGinley MD, Robinson JH, Spahr CS, Sun J, Wahl RC, Patterson SD.

Proteomics. 2001 Jan;1(1):79-92.

PMID:
11680901
28.

Identification and characterization of proSAAS, a granin-like neuroendocrine peptide precursor that inhibits prohormone processing.

Fricker LD, McKinzie AA, Sun J, Curran E, Qian Y, Yan L, Patterson SD, Courchesne PL, Richards B, Levin N, Mzhavia N, Devi LA, Douglass J.

J Neurosci. 2000 Jan 15;20(2):639-48.

29.

Chicken macrophage stimulating protein is a ligand of the receptor protein-tyrosine kinase Sea.

Wahl RC, Hsu RY, Huff JL, Jelinek MA, Chen K, Courchesne P, Patterson SD, Parsons JT, Welcher AA.

J Biol Chem. 1999 Sep 10;274(37):26361-8.

30.

Identification of proteins by matrix-assisted laser desorption/ionization mass spectrometry using peptide and fragment ion masses.

Courchesne PL, Patterson SD.

Methods Mol Biol. 1999;112:487-511. Review. No abstract available.

PMID:
10027273
31.

Two-dimensional electrophoresis of human placental mitochondria and protein identification by mass spectrometry: toward a human mitochondrial proteome.

Rabilloud T, Kieffer S, Procaccio V, Louwagie M, Courchesne PL, Patterson SD, Martinez P, Garin J, Lunardi J.

Electrophoresis. 1998 May;19(6):1006-14.

PMID:
9638947
32.

Optimization of capillary chromatography ion trap-mass spectrometry for identification of gel-separated proteins.

Courchesne PL, Jones MD, Robinson JH, Spahr CS, McCracken S, Bentley DL, Luethy R, Patterson SD.

Electrophoresis. 1998 May;19(6):956-67.

PMID:
9638942
33.

Mutation of Cys672 allows recombinant expression of activatible macrophage-stimulating protein.

Wahl RC, Costigan VJ, Batac JP, Chen K, Cam L, Courchesne PL, Patterson SD, Zhang K, Pacifici RE.

J Biol Chem. 1997 Jun 13;272(24):15053-6.

35.

Manual microcolumn chromatography for sample cleanup before mass spectrometry.

Courchesne PL, Patterson SD.

Biotechniques. 1997 Feb;22(2):244-6, 248-50. No abstract available.

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