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Items: 1 to 50 of 149

1.

Structural requirements for mitotane activity: development of analogs for treatment of adrenal cancer.

Schteingart DE, Sinsheimer JE, Benitez RS, Homan DF, Johnson TD, Counsell RE.

Anticancer Res. 2012 Jul;32(7):2711-20.

PMID:
22753730
2.

Synthesis and structure-activity relationship effects on the tumor avidity of radioiodinated phospholipid ether analogues.

Pinchuk AN, Rampy MA, Longino MA, Skinner RW, Gross MD, Weichert JP, Counsell RE.

J Med Chem. 2006 Apr 6;49(7):2155-65.

PMID:
16570911
3.

Hepatobiliary imaging using a novel hepatocyte-selective CT contrast agent.

Bakan DA, Lee FT Jr, Weichert JP, Longino MA, Counsell RE.

Acad Radiol. 2002 May;9 Suppl 1:S194-9. No abstract available.

PMID:
12019866
4.

Percutaneous CT lymphography using a new polyiodinated biomimetic microemulsion.

Wisner ER, Weichert JP, Longino MA, Counsell RE, Weisbrode SE.

Acad Radiol. 2002 May;9 Suppl 1:S191-3. No abstract available.

PMID:
12019865
5.

A surface-modified chylomicron remnant-like emulsion for percutaneous computed tomography lymphography: synthesis and preliminary imaging findings.

Wisner ER, Weichert JP, Longino MA, Counsell RE, Weisbrode SE.

Invest Radiol. 2002 Apr;37(4):232-9.

PMID:
11923646
6.

Imaging efficacy of a hepatocyte-selective polyiodinated triglyceride for contrast-enhanced computed tomography.

Bakan DA, Doerr-Stevens JK, Weichert JP, Longino MA, Lee FT Jr, Counsell RE.

Am J Ther. 2001 Sep-Oct;8(5):359-65.

PMID:
11550077
9.

Lipid-based blood-pool CT imaging of the liver.

Weichert JP, Lee FT Jr, Longino MA, Chosy SG, Counsell RE.

Acad Radiol. 1998 Apr;5 Suppl 1:S16-9; discussion S28-30.

PMID:
9561034
10.

Adrenal proteins bound by a reactive intermediate of mitotane.

Cai W, Counsell RE, Schteingart DE, Sinsheimer JE, Vaz AD, Wotring LL.

Cancer Chemother Pharmacol. 1997;39(6):537-40.

12.

Biological disposition and imaging of a radioiodinated alkylphosphocholine in two rodent models of breast cancer.

Rampy MA, Brown RS, Pinchuk AN, Weichert JP, Skinner RW, Fisher SJ, Wahl RL, Gross MD, Ethier SP, Counsell RE.

J Nucl Med. 1996 Sep;37(9):1540-5.

13.

Computed tomography scanning of hepatic tumors with polyiodinated triglycerides.

Weichert JP, Lee FT Jr, Longino MA, Bakan DA, Spigarelli MG, Francis IR, Counsell RE.

Acad Radiol. 1996 Aug;3 Suppl 2:S229-31. No abstract available.

PMID:
8796569
14.
15.

Gas chromatographic-electron capture determination of 2,4'-dichlorodiphenylacetic acid from in-vitro adrenal transformations of mitotane and its analogs.

Sinsheimer JE, Counsell RE, Cai W, Gopalaswamy R, Mahalakshmi P, Piñeiro-Sánchez ML, Ruangwises N, Schteingart DE.

J Pharm Biomed Anal. 1996 May;14(7):861-6. No abstract available.

PMID:
8809711
16.

Computed tomography scanning of Morris hepatomas with liver-specific polyiodinated triglycerides.

Weichert JP, Longino MA, Spigarelli MG, Lee FT Jr, Schwendner SW, Counsell RE.

Acad Radiol. 1996 May;3(5):412-7.

PMID:
8796694
17.

Synthesis and biological evaluation of radioiodinated phospholipid ether stereoisomers.

Rampy MA, Pinchuk AN, Weichert JP, Skinner RW, Fisher SJ, Wahl RL, Gross MD, Counsell RE.

J Med Chem. 1995 Aug 4;38(16):3156-62.

PMID:
7636878
18.

Bovine adrenal cortex transformations of mitotane [1-(2-chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane; o,p'-DDD] and its p,p'- and m,p'-isomers.

Cai W, Benitez R, Counsell RE, Djanegara T, Schteingart DE, Sinsheimer JE, Wotring LL.

Biochem Pharmacol. 1995 May 17;49(10):1483-9.

PMID:
7763292
19.

Synthesis and biological evaluation of radioiodinated phospholipid ether analogs.

Rampy MA, Chou TS, Pinchuk AN, Skinner RW, Gross MD, Fisher S, Wahl R, Counsell RE.

Nucl Med Biol. 1995 May;22(4):505-12.

PMID:
7550028
20.

Polyiodinated triglyceride analogs as potential computed tomography imaging agents for the liver.

Weichert JP, Longino MA, Bakan DA, Spigarelli MG, Chou TS, Schwendner SW, Counsell RE.

J Med Chem. 1995 Feb 17;38(4):636-46.

PMID:
7861412
21.

Metabolic activation and binding of mitotane in adrenal cortex homogenates.

Cai W, Counsell RE, Djanegara T, Schteingart DE, Sinsheimer JE, Wotring LL.

J Pharm Sci. 1995 Feb;84(2):134-8.

PMID:
7738789
22.

alpha-Methylene and glycidic acid analogs of IPPA as potential myocardial imaging agents.

Ruyan MK, Bakan DA, Skinner RW, Newman C, Gross MD, Counsell RE.

Nucl Med Biol. 1995 Jan;22(1):95-103.

PMID:
7735176
23.

Targeted polyiodinated triglycerides for hepatic computed tomography.

Weichert JP, Longino MA, Bakan DA, Spigarelli MG, Schwendner SW, Francis IR, Counsell RE.

Invest Radiol. 1994 Jun;29 Suppl 2:S284-5. No abstract available.

PMID:
7928257
24.

Biodistribution, metabolism, and excretion of radioiodinated phospholipid ether analogs in tumor-bearing rats.

Plotzke KP, Rampy MA, Meyer K, Ruyan M, Fisher SJ, Wahl RL, Skinner RW, Gross MD, Counsell RE.

J Nucl Biol Med. 1993 Dec;37(4):264-72.

PMID:
8172971
25.

Selective localization of a radioiodinated phospholipid ether analog in human tumor xenografts.

Plotzke KP, Fisher SJ, Wahl RL, Olken NM, Skinner S, Gross MD, Counsell RE.

J Nucl Med. 1993 May;34(5):787-92.

26.

Comparison of the adrenalytic activity of mitotane and a methylated homolog on normal adrenal cortex and adrenal cortical carcinoma.

Schteingart DE, Sinsheimer JE, Counsell RE, Abrams GD, McClellan N, Djanegara T, Hines J, Ruangwises N, Benitez R, Wotring LL.

Cancer Chemother Pharmacol. 1993;31(6):459-66.

27.

Comparison of methods for incorporating a radioiodinated residualizing cholesteryl ester analog into low density lipoprotein.

Deforge LE, Degalan MR, Ruyan MK, Newton RS, Counsell RE.

Int J Rad Appl Instrum B. 1992 Oct;19(7):775-82.

28.

Selective localization of radioiodinated alkylphosphocholine derivatives in tumors.

Plotzke KP, Haradahira T, Stancato L, Olken NM, Skinner S, Gross MD, Wahl RL, Counsell RE.

Int J Rad Appl Instrum B. 1992 Oct;19(7):765-73.

29.

Potential organ or tumor imaging agents. 32. A triglyceride ester of p-iodophenyl pentadecanoic acid as a potential hepatic imaging agent.

Schwendner SW, Weichert JP, Longino MA, Gross MD, Counsell RE.

Int J Rad Appl Instrum B. 1992 Aug;19(6):639-50.

30.

Synthesis and evaluation of radioiodinated cholesteryl ethers as lipoprotein probes.

DeForge LE, Ruyan MK, Schwendner SW, Newton RS, Counsell RE.

Bioconjug Chem. 1991 Jul-Aug;2(4):254-60.

PMID:
1772907
31.
32.

Lipoproteins as carriers for organ-imaging radiopharmaceuticals.

Counsell RE, Schwendner SW, DeForge LE, DeGalan MR, Newton RS.

Targeted Diagn Ther. 1991;5:251-314. Review. No abstract available.

PMID:
1797169
33.

Tumor visualization with a radioiodinated phospholipid ether.

Counsell RE, Schwendner SW, Meyer KL, Haradahira T, Gross MD.

J Nucl Med. 1990 Mar;31(3):332-6.

34.

Noninvasive assessment of lipid disposition in treated and untreated atherosclerotic rabbits.

DeForge LE, Schwendner SW, DeGalan MR, McConnell DS, Counsell RE.

Pharm Res. 1989 Dec;6(12):1011-6.

35.

Potential tumor or organ-imaging agents. 30. Radioiodinated phospholipid ethers.

Meyer KL, Schwendner SW, Counsell RE.

J Med Chem. 1989 Sep;32(9):2142-7.

PMID:
2769685
36.

Iodoaryl analogues of dioctanoylglycerol and 1-oleoyl-2-acetylglycerol as probes for protein kinase C.

Strawn LM, Martell RE, Simpson RU, Leach KL, Counsell RE.

J Med Chem. 1989 Sep;32(9):2104-10.

PMID:
2769682
37.

Lipoprotein incorporation enhances radioiodinated cholesteryl ester uptake into steroid hormone-secreting tissues.

Counsell RE, Schwendner SW, Gross MD, Longino MA, McConnell DS.

J Nucl Med. 1989 Jun;30(6):1088-94.

38.

Synthesis and evaluation of iodinated analogues of diacylglycerols as potential probes for protein kinase C.

Strawn LM, Martell RE, Simpson RU, Leach KL, Counsell RE.

J Med Chem. 1989 Mar;32(3):643-8.

PMID:
2918512
39.

Potential tumor- or organ-imaging agents. 29. Radioiodinated esters and amides of 20-hydroxy- and 20-aminopregn-5-en-3 beta-ols.

Haradahira T, Schwendner SW, Kojima M, Counsell RE.

J Med Chem. 1989 Mar;32(3):609-12.

PMID:
2918507
40.

Potential tumor or organ imaging agents--31. Radioiodinated sterol benzoates and carbamates.

Van Dort M, Santay L, Schwendner SW, Counsell RE.

Int J Rad Appl Instrum B. 1989;16(6):603-7.

41.

Synthesis of 11C-labelled thymidine for tumor visualization using positron emission tomography.

Poupeye E, Counsell RE, De Leenheer A, Slegers G, Goethals P.

Int J Rad Appl Instrum A. 1989;40(1):57-61.

42.

Iodine-125 cholesteryl iopanoate for measuring extent of atherosclerosis in rabbits.

DeGalan MR, Schwendner SW, Skinner RW, Longino MA, Gross M, Counsell RE.

J Nucl Med. 1988 Apr;29(4):503-8.

43.

Radioiodinated p-iodoclonidine: a high-affinity probe for the alpha 2-adrenergic receptor.

Van Dort M, Neubig R, Counsell RE.

J Med Chem. 1987 Jul;30(7):1241-4.

PMID:
3037080
44.

Potential tumor- or organ-imaging agents. 28. Radioiodinated esters of cholesterol and pregnenolone.

Van Dort M, Schwendner SW, Counsell RE.

Steroids. 1987 Jun;49(6):531-41.

45.

Potential tumor- or organ-imaging agents. 27. Polyiodinated 1,3-disubstituted and 1,2,3-trisubstituted triacylglycerols.

Weichert JP, Groziak MP, Longino MA, Schwendner SW, Counsell RE.

J Med Chem. 1986 Dec;29(12):2457-65.

PMID:
3783605
46.

Potential tumor- or organ-imaging agents. 26. Polyiodinated 2-substituted triacylglycerols as hepatographic agents.

Weichert JP, Longino MA, Schwendner SW, Counsell RE.

J Med Chem. 1986 Sep;29(9):1674-82.

PMID:
3746816
47.

Radioiodinated Cholesteryl lopanoate as a Potential Probe for the in Vivo Visualization of Atherosclerotic Lesions in Animals.

De Galan MR, Schwendner SW, Weichert JP, Counsell RE.

Pharm Res. 1986 Feb;3(1):52-5. doi: 10.1023/A:1016376916448.

48.

7 alpha-substituted derivatives of androstenedione as inhibitors of estrogen biosynthesis.

Darby MV, Lovett JA, Brueggemeier RW, Groziak MP, Counsell RE.

J Med Chem. 1985 Jun;28(6):803-7.

PMID:
4009603
49.
50.

In vitro and in vivo metabolism of a radioiodinated analog of 1-(2-chlorophenyl)-1-(4-chlorophenyl)-2,-dichloroethane.

Pohland RC, Counsell RE.

Drug Metab Dispos. 1985 Jan-Feb;13(1):113-5. No abstract available.

PMID:
2858368

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