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Items: 47

1.

Survival after adjuvant radiation therapy in localized small cell lung cancer treated with complete resection.

Engelhardt KE, Coughlin JM, DeCamp MM, Denlinger CE, Meyerson SL, Bharat A, Odell DD.

J Thorac Cardiovasc Surg. 2019 Dec;158(6):1665-1677.e2. doi: 10.1016/j.jtcvs.2019.08.031. Epub 2019 Sep 9.

PMID:
31627955
2.

High availability of the α7 nicotinic acetylcholine receptor in brains of individuals with mild cognitive impairment: A pilot study using 18F-ASEM PET.

Coughlin JM, Rubin LH, Du Y, Rowe SP, Crawford JL, Rosenthal HB, Frey SM, Marshall ES, Shinehouse LK, Chen A, Speck CL, Wang Y, Lesniak WG, Minn I, Bakker A, Kamath V, Smith GS, Albert MS, Behnam Azad B, Dannals RF, Horti AG, Wong DF, Pomper MG.

J Nucl Med. 2019 Aug 16. pii: jnumed.119.230979. doi: 10.2967/jnumed.119.230979. [Epub ahead of print]

PMID:
31420499
3.

Characterizing the Link Between Glial Activation and Changed Functional Connectivity in National Football League Players Using Multimodal Neuroimaging.

Peters ME, Rahman S, Coughlin JM, Pomper MG, Sair HI.

J Neuropsychiatry Clin Neurosci. 2019 Aug 9:appineuropsych18110274. doi: 10.1176/appi.neuropsych.18110274. [Epub ahead of print]

PMID:
31394988
4.

Minimizing Opioid Prescribing in Surgery (MOPiS) Initiative: An Analysis of Implementation Barriers.

Coughlin JM, Shallcross ML, Schäfer WLA, Buckley BA, Stulberg JJ, Holl JL, Bilimoria KY, Johnson JK.

J Surg Res. 2019 Jul;239:309-319. doi: 10.1016/j.jss.2019.03.006. Epub 2019 Mar 22.

PMID:
30908977
5.

Opportunities in precision psychiatry using PET neuroimaging in psychosis.

Coughlin JM, Horti AG, Pomper MG.

Neurobiol Dis. 2019 Nov;131:104428. doi: 10.1016/j.nbd.2019.03.016. Epub 2019 Mar 20. Review.

PMID:
30904669
6.

Assessing Brain Metabolism With 7-T Proton Magnetic Resonance Spectroscopy in Patients With First-Episode Psychosis.

Wang AM, Pradhan S, Coughlin JM, Trivedi A, DuBois SL, Crawford JL, Sedlak TW, Nucifora FC Jr, Nestadt G, Nucifora LG, Schretlen DJ, Sawa A, Barker PB.

JAMA Psychiatry. 2019 Mar 1;76(3):314-323. doi: 10.1001/jamapsychiatry.2018.3637.

PMID:
30624573
7.

Imaging glial activation in patients with post-treatment Lyme disease symptoms: a pilot study using [11C]DPA-713 PET.

Coughlin JM, Yang T, Rebman AW, Bechtold KT, Du Y, Mathews WB, Lesniak WG, Mihm EA, Frey SM, Marshall ES, Rosenthal HB, Reekie TA, Kassiou M, Dannals RF, Soloski MJ, Aucott JN, Pomper MG.

J Neuroinflammation. 2018 Dec 19;15(1):346. doi: 10.1186/s12974-018-1381-4.

8.

Sulforaphane Augments Glutathione and Influences Brain Metabolites in Human Subjects: A Clinical Pilot Study.

Sedlak TW, Nucifora LG, Koga M, Shaffer LS, Higgs C, Tanaka T, Wang AM, Coughlin JM, Barker PB, Fahey JW, Sawa A.

Mol Neuropsychiatry. 2018 May;3(4):214-222. doi: 10.1159/000487639. Epub 2018 Apr 17.

9.

Microglial activation is inversely associated with cognition in individuals living with HIV on effective antiretroviral therapy.

Rubin LH, Sacktor N, Creighton J, Du Y, Endres CJ, Pomper MG, Coughlin JM.

AIDS. 2018 Jul 31;32(12):1661-1667. doi: 10.1097/QAD.0000000000001858.

10.

Positron Emission Tomography Studies of the Glial Cell Marker Translocator Protein in Patients With Psychosis: A Meta-analysis Using Individual Participant Data.

Plavén-Sigray P, Matheson GJ, Collste K, Ashok AH, Coughlin JM, Howes OD, Mizrahi R, Pomper MG, Rusjan P, Veronese M, Wang Y, Cervenka S.

Biol Psychiatry. 2018 Sep 15;84(6):433-442. doi: 10.1016/j.biopsych.2018.02.1171. Epub 2018 Mar 6.

11.

18F-XTRA PET for Enhanced Imaging of the Extrathalamic α4β2 Nicotinic Acetylcholine Receptor.

Coughlin JM, Slania S, Du Y, Rosenthal HB, Lesniak WG, Minn I, Smith GS, Dannals RF, Kuwabara H, Wong DF, Wang Y, Horti AG, Pomper MG.

J Nucl Med. 2018 Oct;59(10):1603-1608. doi: 10.2967/jnumed.117.205492. Epub 2018 Mar 1.

12.

Decoupling of Brain Temperature and Glutamate in Recent Onset of Schizophrenia: A 7T Proton Magnetic Resonance Spectroscopy Study.

Posporelis S, Coughlin JM, Marsman A, Pradhan S, Tanaka T, Wang H, Varvaris M, Ward R, Higgs C, Edwards JA, Ford CN, Kim PK, Lloyd AM, Edden RAE, Schretlen DJ, Cascella NG, Barker PB, Sawa A.

Biol Psychiatry Cogn Neurosci Neuroimaging. 2018 Mar;3(3):248-254. doi: 10.1016/j.bpsc.2017.04.003. Epub 2017 Apr 21.

13.

Translocator protein (TSPO) and stress cascades in mouse models of psychosis with inflammatory disturbances.

Fukudome D, Hayes LN, Faust TE, Foss CA, Kondo MA, Lee BJ, Saito A, Kano SI, Coughlin JM, Kamiya A, Pomper MG, Sawa A, Niwa M.

Schizophr Res. 2018 Jul;197:492-497. doi: 10.1016/j.schres.2018.01.015. Epub 2018 Feb 3.

14.

Reconceptualization of translocator protein as a biomarker of neuroinflammation in psychiatry.

Notter T, Coughlin JM, Sawa A, Meyer U.

Mol Psychiatry. 2018 Jan;23(1):36-47. doi: 10.1038/mp.2017.232. Epub 2017 Dec 5. Review.

PMID:
29203847
15.

The distribution of the alpha7 nicotinic acetylcholine receptor in healthy aging: An in vivo positron emission tomography study with [18F]ASEM.

Coughlin JM, Du Y, Rosenthal HB, Slania S, Min Koo S, Park A, Solomon G, Vranesic M, Antonsdottir I, Speck CL, Rootes-Murdy K, Lerner A, Rowe SP, Wang Y, Lesniak WG, Minn I, Bakker A, Smith GS, Dannals RF, Kuwabara H, Horti A, Wong DF, Pomper MG.

Neuroimage. 2018 Jan 15;165:118-124. doi: 10.1016/j.neuroimage.2017.10.009. Epub 2017 Oct 7.

16.

The Low-Affinity Binding of Second Generation Radiotracers Targeting TSPO is Associated with a Unique Allosteric Binding Site.

Rojas C, Stathis M, Coughlin JM, Pomper M, Slusher BS.

J Neuroimmune Pharmacol. 2018 Mar;13(1):1-5. doi: 10.1007/s11481-017-9765-2. Epub 2017 Sep 5.

17.

Translational evaluation of translocator protein as a marker of neuroinflammation in schizophrenia.

Notter T, Coughlin JM, Gschwind T, Weber-Stadlbauer U, Wang Y, Kassiou M, Vernon AC, Benke D, Pomper MG, Sawa A, Meyer U.

Mol Psychiatry. 2018 Feb;23(2):323-334. doi: 10.1038/mp.2016.248. Epub 2017 Jan 17.

PMID:
28093569
18.

Imaging of Glial Cell Activation and White Matter Integrity in Brains of Active and Recently Retired National Football League Players.

Coughlin JM, Wang Y, Minn I, Bienko N, Ambinder EB, Xu X, Peters ME, Dougherty JW, Vranesic M, Koo SM, Ahn HH, Lee M, Cottrell C, Sair HI, Sawa A, Munro CA, Nowinski CJ, Dannals RF, Lyketsos CG, Kassiou M, Smith G, Caffo B, Mori S, Guilarte TR, Pomper MG.

JAMA Neurol. 2017 Jan 1;74(1):67-74. doi: 10.1001/jamaneurol.2016.3764.

19.

Reduced superoxide dismutase-1 (SOD1) in cerebrospinal fluid of patients with early psychosis in association with clinical features.

Coughlin JM, Hayes LN, Tanaka T, Xiao M, Yolken RH, Worley P, Leweke FM, Sawa A.

Schizophr Res. 2017 May;183:64-69. doi: 10.1016/j.schres.2016.10.040. Epub 2016 Nov 23.

PMID:
27889384
20.

Neuroimaging of translocator protein in patients with systemic lupus erythematosus: a pilot study using [11C]DPA-713 positron emission tomography.

Wang Y, Coughlin JM, Ma S, Endres CJ, Kassiou M, Sawa A, Dannals RF, Petri M, Pomper MG.

Lupus. 2017 Feb;26(2):170-178. doi: 10.1177/0961203316657432. Epub 2016 Jul 11.

21.

In vivo markers of inflammatory response in recent-onset schizophrenia: a combined study using [(11)C]DPA-713 PET and analysis of CSF and plasma.

Coughlin JM, Wang Y, Ambinder EB, Ward RE, Minn I, Vranesic M, Kim PK, Ford CN, Higgs C, Hayes LN, Schretlen DJ, Dannals RF, Kassiou M, Sawa A, Pomper MG.

Transl Psychiatry. 2016 Apr 12;6:e777. doi: 10.1038/tp.2016.40.

22.

Novel BAC Mouse Model of Huntington's Disease with 225 CAG Repeats Exhibits an Early Widespread and Stable Degenerative Phenotype.

Wegrzynowicz M, Bichell TJ, Soares BD, Loth MK, McGlothan JS, Mori S, Alikhan FS, Hua K, Coughlin JM, Holt HK, Jetter CS, Pomper MG, Osmand AP, Guilarte TR, Bowman AB.

J Huntingtons Dis. 2015;4(1):17-36.

23.

Decoupling of N-acetyl-aspartate and glutamate within the dorsolateral prefrontal cortex in schizophrenia.

Coughlin JM, Tanaka T, Marsman A, Wang H, Bonekamp S, Kim PK, Higgs C, Varvaris M, Edden RA, Pomper M, Schretlen D, Barker PB, Sawa A.

Curr Mol Med. 2015;15(2):176-83.

24.

Rhodium(II) metallopeptide catalyst design enables fine control in selective functionalization of natural SH3 domains.

Vohidov F, Coughlin JM, Ball ZT.

Angew Chem Int Ed Engl. 2015 Apr 7;54(15):4587-91. doi: 10.1002/anie.201411745. Epub 2015 Feb 16.

PMID:
25688989
25.

Neuroinflammation and brain atrophy in former NFL players: An in vivo multimodal imaging pilot study.

Coughlin JM, Wang Y, Munro CA, Ma S, Yue C, Chen S, Airan R, Kim PK, Adams AV, Garcia C, Higgs C, Sair HI, Sawa A, Smith G, Lyketsos CG, Caffo B, Kassiou M, Guilarte TR, Pomper MG.

Neurobiol Dis. 2015 Feb;74:58-65. doi: 10.1016/j.nbd.2014.10.019. Epub 2014 Nov 7.

26.

Inhibiting prolyl isomerase activity by hybrid organic-inorganic molecules containing rhodium(II) fragments.

Coughlin JM, Kundu R, Cooper JC, Ball ZT.

Bioorg Med Chem Lett. 2014 Nov 15;24(22):5203-6. doi: 10.1016/j.bmcl.2014.09.068. Epub 2014 Oct 2.

PMID:
25442313
27.

BlmB and TlmB provide resistance to the bleomycin family of antitumor antibiotics by N-acetylating metal-free bleomycin, tallysomycin, phleomycin, and zorbamycin.

Coughlin JM, Rudolf JD, Wendt-Pienkowski E, Wang L, Unsin C, Galm U, Yang D, Tao M, Shen B.

Biochemistry. 2014 Nov 11;53(44):6901-9. doi: 10.1021/bi501121e. Epub 2014 Oct 23.

28.

Inflammatory molecular signature associated with infectious agents in psychosis.

Hayes LN, Severance EG, Leek JT, Gressitt KL, Rohleder C, Coughlin JM, Leweke FM, Yolken RH, Sawa A.

Schizophr Bull. 2014 Sep;40(5):963-72. doi: 10.1093/schbul/sbu052. Epub 2014 Apr 17.

29.

Regional brain distribution of translocator protein using [(11)C]DPA-713 PET in individuals infected with HIV.

Coughlin JM, Wang Y, Ma S, Yue C, Kim PK, Adams AV, Roosa HV, Gage KL, Stathis M, Rais R, Rojas C, McGlothan JL, Watkins CC, Sacktor N, Guilarte TR, Zhou Y, Sawa A, Slusher BS, Caffo B, Kassiou M, Endres CJ, Pomper MG.

J Neurovirol. 2014 Jun;20(3):219-32. doi: 10.1007/s13365-014-0239-5. Epub 2014 Feb 25.

30.

A designer bleomycin with significantly improved DNA cleavage activity.

Huang SX, Feng Z, Wang L, Galm U, Wendt-Pienkowski E, Yang D, Tao M, Coughlin JM, Duan Y, Shen B.

J Am Chem Soc. 2012 Aug 15;134(32):13501-9. doi: 10.1021/ja3056535. Epub 2012 Aug 6.

31.

Catalytic protein modification with dirhodium metallopeptides: specificity in designed and natural systems.

Chen Z, Vohidov F, Coughlin JM, Stagg LJ, Arold ST, Ladbury JE, Ball ZT.

J Am Chem Soc. 2012 Jun 20;134(24):10138-45. doi: 10.1021/ja302284p. Epub 2012 Jun 7.

PMID:
22621321
32.

Asystole in ultrabrief pulse electroconvulsive therapy.

Coughlin JM, Rodenbach K, Lee PH, Hayat MJ, Griffin MM, Mirski MA, Reti IM.

J ECT. 2012 Sep;28(3):165-9. doi: 10.1097/YCT.0b013e31825003f9.

PMID:
22513509
33.

Marked reduction of soluble superoxide dismutase-1 (SOD1) in cerebrospinal fluid of patients with recent-onset schizophrenia.

Coughlin JM, Ishizuka K, Kano SI, Edwards JA, Seifuddin FT, Shimano MA, Daley EL, Zandi PP, Leweke FM, Cascella NG, Pomper MG, Yolken RH, Sawa A.

Mol Psychiatry. 2013 Jan;18(1):10-1. doi: 10.1038/mp.2012.6. Epub 2012 Feb 21. No abstract available.

34.

Radiation dosimetry and biodistribution of the TSPO ligand 11C-DPA-713 in humans.

Endres CJ, Coughlin JM, Gage KL, Watkins CC, Kassiou M, Pomper MG.

J Nucl Med. 2012 Feb;53(2):330-5. doi: 10.2967/jnumed.111.094565. Epub 2012 Jan 12.

35.

Evaluation of two intensive care delirium screening tools for non-critically ill hospitalized patients.

Neufeld KJ, Hayat MJ, Coughlin JM, Huberman AL, Leistikow NA, Krumm SK, Needham DM.

Psychosomatics. 2011 Mar-Apr;52(2):133-40. doi: 10.1016/j.psym.2010.12.018.

PMID:
21397105
36.

Comparative analysis of the biosynthetic gene clusters and pathways for three structurally related antitumor antibiotics: bleomycin, tallysomycin, and zorbamycin.

Galm U, Wendt-Pienkowski E, Wang L, Huang SX, Unsin C, Tao M, Coughlin JM, Shen B.

J Nat Prod. 2011 Mar 25;74(3):526-36. doi: 10.1021/np1008152. Epub 2011 Jan 6. Review.

37.

Oxazolomycin biosynthesis in Streptomyces albus JA3453 featuring an "acyltransferase-less" type I polyketide synthase that incorporates two distinct extender units.

Zhao C, Coughlin JM, Ju J, Zhu D, Wendt-Pienkowski E, Zhou X, Wang Z, Shen B, Deng Z.

J Biol Chem. 2010 Jun 25;285(26):20097-108. doi: 10.1074/jbc.M109.090092. Epub 2010 Apr 20.

38.

Functional characterization of tlmH in Streptoalloteichus hindustanus E465-94 ATCC 31158 unveiling new insight into tallysomycin biosynthesis and affording a novel bleomycin analog.

Tao M, Wang L, Wendt-Pienkowski E, Zhang N, Yang D, Galm U, Coughlin JM, Xu Z, Shen B.

Mol Biosyst. 2010 Feb;6(2):349-56. doi: 10.1039/b918106g. Epub 2009 Dec 1.

39.

Type I polyketide synthases that require discrete acyltransferases.

Cheng YQ, Coughlin JM, Lim SK, Shen B.

Methods Enzymol. 2009;459:165-86. doi: 10.1016/S0076-6879(09)04608-4.

40.

Functional characterization of tlmK unveiling unstable carbinolamide intermediates in the tallysomycin biosynthetic pathway.

Wang L, Tao M, Wendt-Pienkoski E, Galm U, Coughlin JM, Shen B.

J Biol Chem. 2009 Mar 27;284(13):8256-64. doi: 10.1074/jbc.M900640200. Epub 2009 Feb 3.

41.

The biosynthetic gene cluster of zorbamycin, a member of the bleomycin family of antitumor antibiotics, from Streptomyces flavoviridis ATCC 21892.

Galm U, Wendt-Pienkowski E, Wang L, George NP, Oh TJ, Yi F, Tao M, Coughlin JM, Shen B.

Mol Biosyst. 2009 Jan;5(1):77-90. doi: 10.1039/b814075h. Epub 2008 Nov 12.

42.

In vivo manipulation of the bleomycin biosynthetic gene cluster in Streptomyces verticillus ATCC15003 revealing new insights into its biosynthetic pathway.

Galm U, Wang L, Wendt-Pienkowski E, Yang R, Liu W, Tao M, Coughlin JM, Shen B.

J Biol Chem. 2008 Oct 17;283(42):28236-45. doi: 10.1074/jbc.M804971200. Epub 2008 Aug 12.

43.

Glycopeptide antitumor antibiotic zorbamycin from Streptomyces flavoviridis ATCC 21892: strain improvement and structure elucidation.

Wang L, Yun BS, George NP, Wendt-Pienkowski E, Galm U, Oh TJ, Coughlin JM, Zhang G, Tao M, Shen B.

J Nat Prod. 2007 Mar;70(3):402-6. Epub 2007 Feb 21.

44.

Novel syn intramolecular pathway in base-catalyzed 1,2-elimination reactions of beta-acetoxy esters.

Mohrig JR, Carlson HK, Coughlin JM, Hofmeister GE, McMartin LA, Rowley EG, Trimmer EE, Wild AJ, Schultz SC.

J Org Chem. 2007 Feb 2;72(3):793-8.

PMID:
17253797
45.

The tallysomycin biosynthetic gene cluster from Streptoalloteichus hindustanus E465-94 ATCC 31158 unveiling new insights into the biosynthesis of the bleomycin family of antitumor antibiotics.

Tao M, Wang L, Wendt-Pienkowski E, George NP, Galm U, Zhang G, Coughlin JM, Shen B.

Mol Biosyst. 2007 Jan;3(1):60-74. Epub 2006 Nov 28.

PMID:
17216057
46.

Characterization of CTG/CAG repeats on chromosome 18: a study of bipolar disorder.

Swift-Scanlan T, Coughlin JM, Lan TH, Potash JB, Ingersoll RG, Depaulo R Jr, Ross CA, McInnis MG.

Psychiatr Genet. 2005 Jun;15(2):91-9.

PMID:
15900223
47.

Genetic analysis of the (CTG)n NOTCH4 polymorphism in 65 multiplex bipolar pedigrees.

Swift-Scanlan T, Lan TH, Fallin MD, Coughlin JM, Potash JB, DePaulo JR, McInnis MG.

Psychiatr Genet. 2002 Mar;12(1):43-7.

PMID:
11901359

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