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Dietary Advanced Glycation End Products: Digestion, Metabolism and Modulation of Gut Microbial Ecology.

Snelson M, Coughlan MT.

Nutrients. 2019 Jan 22;11(2). pii: E215. doi: 10.3390/nu11020215. Review.


Modulation of the Gut Microbiota by Resistant Starch as a Treatment of Chronic Kidney Diseases: Evidence of Efficacy and Mechanistic Insights.

Snelson M, Kellow NJ, Coughlan MT.

Adv Nutr. 2019 Mar 1;10(2):303-320. doi: 10.1093/advances/nmy068.


The p53 Pathway in Glioblastoma.

Zhang Y, Dube C, Gibert M Jr, Cruickshanks N, Wang B, Coughlan M, Yang Y, Setiady I, Deveau C, Saoud K, Grello C, Oxford M, Yuan F, Abounader R.

Cancers (Basel). 2018 Sep 1;10(9). pii: E297. doi: 10.3390/cancers10090297. Review.


Assessment of Open Syndesmosis Reduction Techniques in an Unbroken Fibula Model: Visualization Versus Palpation.

Pang EQ, Coughlan M, Bonaretti S, Finlay A, Bellino M, Bishop JA, Gardner MJ.

J Orthop Trauma. 2019 Jan;33(1):e14-e18. doi: 10.1097/BOT.0000000000001322.


Nonpupil adaptive optics for visual simulation of a customized contact lens.

Coughlan MF, Goncharov AV.

Appl Opt. 2018 Aug 1;57(22):E57-E63. doi: 10.1364/AO.57.000E57.


Use of Readily Accessible Inflammatory Markers to Predict Diabetic Kidney Disease.

Winter L, Wong LA, Jerums G, Seah JM, Clarke M, Tan SM, Coughlan MT, MacIsaac RJ, Ekinci EI.

Front Endocrinol (Lausanne). 2018 May 22;9:225. doi: 10.3389/fendo.2018.00225. eCollection 2018. Review.


Avoiding Neurovascular Risk During Percutaneous Clamp Reduction of Spiral Tibial Shaft Fractures: An Anatomic Correlation With Computed Tomography.

Horrigan PB, Coughlan MJ, DeBaun MR, Schultz B, Bishop JA, Gardner MJ.

J Orthop Trauma. 2018 Sep;32(9):e376-e380. doi: 10.1097/BOT.0000000000001239.


A Prospective, Randomized, Multicenter Study Comparing Silicated Calcium Phosphate versus BMP-2 Synthetic Bone Graft in Posterolateral Instrumented Lumbar Fusion for Degenerative Spinal Disorders.

Coughlan M, Davies M, Mostert AK, Nanda D, Willems PC, Rosenberg G, Ferch R.

Spine (Phila Pa 1976). 2018 Aug 1;43(15):E860-E868. doi: 10.1097/BRS.0000000000002678.


Influences of Native American land use on the Colonial Euro-American settlement of the South Carolina Piedmont.

Coughlan MR, Nelson DR.

PLoS One. 2018 Mar 29;13(3):e0195036. doi: 10.1371/journal.pone.0195036. eCollection 2018.


Methods in renal research: Measurement of autophagic flux in the renal cortex ex vivo.

Higgins GC, Nguyen TV, Ramm G, Coughlan MT.

Nephrology (Carlton). 2018 Sep;23(9):815-820. doi: 10.1111/nep.13251.


Obesity associated advanced glycation end products within the human uterine cavity adversely impact endometrial function and embryo implantation competence.

Antoniotti GS, Coughlan M, Salamonsen LA, Evans J.

Hum Reprod. 2018 Apr 1;33(4):654-665. doi: 10.1093/humrep/dey029.


RAGE Deletion Confers Renoprotection by Reducing Responsiveness to Transforming Growth Factor-β and Increasing Resistance to Apoptosis.

Hagiwara S, Sourris K, Ziemann M, Tieqiao W, Mohan M, McClelland AD, Brennan E, Forbes J, Coughlan M, Harcourt B, Penfold S, Wang B, Higgins G, Pickering R, El-Osta A, Thomas MC, Cooper ME, Kantharidis P.

Diabetes. 2018 May;67(5):960-973. doi: 10.2337/db17-0538. Epub 2018 Feb 15.


Bisphenol A induces DSB-ATM-p53 signaling leading to cell cycle arrest, senescence, autophagy, stress response, and estrogen release in human fetal lung fibroblasts.

Mahemuti L, Chen Q, Coughlan MC, Qiao C, Chepelev NL, Florian M, Dong D, Woodworth RG, Yan J, Cao XL, Scoggan KA, Jin X, Willmore WG.

Arch Toxicol. 2018 Apr;92(4):1453-1469. doi: 10.1007/s00204-017-2150-3. Epub 2017 Dec 23.


Perinatal exposure to high dietary advanced glycation end products in transgenic NOD8.3 mice leads to pancreatic beta cell dysfunction.

Borg DJ, Yap FYT, Keshvari S, Simmons DG, Gallo LA, Fotheringham AK, Zhuang A, Slattery RM, Hasnain SZ, Coughlan MT, Kantharidis P, Forbes JM.

Islets. 2018 Jan 2;10(1):10-24. doi: 10.1080/19382014.2017.1405189. Epub 2017 Dec 22.


Opto-mechanical design of a dispersive artificial eye.

Coughlan MF, Mihashi T, Goncharov AV.

Appl Opt. 2017 May 20;56(15):4338-4346. doi: 10.1364/AO.56.004338.


Increased liver AGEs induce hepatic injury mediated through an OST48 pathway.

Zhuang A, Yap FY, Bruce C, Leung C, Plan MR, Sullivan MA, Herath C, McCarthy D, Sourris KC, Kantharidis P, Coughlan MT, Febbraio MA, Hodson MP, Watt MJ, Angus P, Schulz BL, Forbes JM.

Sci Rep. 2017 Sep 25;7(1):12292. doi: 10.1038/s41598-017-12548-4.


NADPH Oxidase Nox5 Accelerates Renal Injury in Diabetic Nephropathy.

Jha JC, Banal C, Okabe J, Gray SP, Hettige T, Chow BSM, Thallas-Bonke V, De Vos L, Holterman CE, Coughlan MT, Power DA, Skene A, Ekinci EI, Cooper ME, Touyz RM, Kennedy CR, Jandeleit-Dahm K.

Diabetes. 2017 Oct;66(10):2691-2703. doi: 10.2337/db16-1585. Epub 2017 Jul 26.


Pediatric Postoperative Pulse Oximetry Monitoring During Transport to the Postanesthesia Care Unit Reduces Frequency of Hypoxemia.

Caruso TJ, Mokhtari TE, Coughlan MJ, Wu DS, Marquez JL, Duan M, Freeman H, Giustini A, Tweedy M, Sharek PJ.

Jt Comm J Qual Patient Saf. 2017 Mar;43(3):146-150. doi: 10.1016/j.jcjq.2016.12.001. Epub 2017 Jan 20.


Stirring the Pot: Can Dietary Modification Alleviate the Burden of CKD?

Snelson M, Clarke RE, Coughlan MT.

Nutrients. 2017 Mar 11;9(3). pii: E265. doi: 10.3390/nu9030265. Review.


The patients' perspective of international normalized ratio self-testing, remote communication of test results and confidence to move to self-management.

Grogan A, Coughlan M, Prizeman G, O'Connell N, O'Mahony N, Quinn K, McKee G.

J Clin Nurs. 2017 Dec;26(23-24):4379-4389. doi: 10.1111/jocn.13767. Epub 2017 Apr 18.


Reduction in Cylindrical Grasp Strength Is Associated With Early Thumb Carpometacarpal Osteoarthritis.

Coughlan MJ, Bourdillon A, Crisco JJ, Kenney D, Weiss AP, Ladd AL.

Clin Orthop Relat Res. 2017 Feb;475(2):522-528. doi: 10.1007/s11999-016-5151-2. Epub 2016 Nov 7.


Bisphenol A exposure alters release of immune and developmental modulators and expression of estrogen receptors in human fetal lung fibroblasts.

Mahemuti L, Chen Q, Coughlan MC, Zhang M, Florian M, Mailloux RJ, Cao XL, Scoggan KA, Willmore WG, Jin X.

J Environ Sci (China). 2016 Oct;48:11-23. doi: 10.1016/j.jes.2016.02.013. Epub 2016 Apr 29.


Challenging the dogma of mitochondrial reactive oxygen species overproduction in diabetic kidney disease.

Coughlan MT, Sharma K.

Kidney Int. 2016 Aug;90(2):272-279. doi: 10.1016/j.kint.2016.02.043. Epub 2016 May 20. Review.


Living on a flammable planet: interdisciplinary, cross-scalar and varied cultural lessons, prospects and challenges.

Roos CI, Scott AC, Belcher CM, Chaloner WG, Aylen J, Bird RB, Coughlan MR, Johnson BR, Johnston FH, McMorrow J, Steelman T; Fire and Mankind Discussion Group.

Philos Trans R Soc Lond B Biol Sci. 2016 Jun 5;371(1696). pii: 20150469. doi: 10.1098/rstb.2015.0469. Review.


Dietary acrylamide exposure in male F344 rats: Dataset of systemic oxidative stress and inflammation markers.

Jin X, Coughlan M, Roberts J, Mehta R, Raju J.

Data Brief. 2016 Feb 14;7:460-7. doi: 10.1016/j.dib.2016.02.024. eCollection 2016 Jun.


Dietary Advanced Glycation End Products and Risk Factors for Chronic Disease: A Systematic Review of Randomised Controlled Trials.

Clarke RE, Dordevic AL, Tan SM, Ryan L, Coughlan MT.

Nutrients. 2016 Mar 1;8(3):125. doi: 10.3390/nu8030125. Review.


Wildland Arson as Clandestine Resource Management: A Space-Time Permutation Analysis and Classification of Informal Fire Management Regimes in Georgia, USA.

Coughlan MR.

Environ Manage. 2016 May;57(5):1077-87. doi: 10.1007/s00267-016-0669-3. Epub 2016 Feb 16.


A potential hidden layer of meteorites below the ice surface of Antarctica.

Evatt GW, Coughlan MJ, Joy KH, Smedley AR, Connolly PJ, Abrahams ID.

Nat Commun. 2016 Feb 16;7:10679. doi: 10.1038/ncomms10679.


Picosecond metrology of laser-driven proton bursts.

Dromey B, Coughlan M, Senje L, Taylor M, Kuschel S, Villagomez-Bernabe B, Stefanuik R, Nersisyan G, Stella L, Kohanoff J, Borghesi M, Currell F, Riley D, Jung D, Wahlström CG, Lewis CL, Zepf M.

Nat Commun. 2016 Feb 10;7:10642. doi: 10.1038/ncomms10642.


Mapping time-course mitochondrial adaptations in the kidney in experimental diabetes.

Coughlan MT, Nguyen TV, Penfold SA, Higgins GC, Thallas-Bonke V, Tan SM, Van Bergen NJ, Sourris KC, Harcourt BE, Thorburn DR, Trounce IA, Cooper ME, Forbes JM.

Clin Sci (Lond). 2016 May;130(9):711-20. doi: 10.1042/CS20150838. Epub 2016 Feb 1.


Deficiency in Apoptosis-Inducing Factor Recapitulates Chronic Kidney Disease via Aberrant Mitochondrial Homeostasis.

Coughlan MT, Higgins GC, Nguyen TV, Penfold SA, Thallas-Bonke V, Tan SM, Ramm G, Van Bergen NJ, Henstridge DC, Sourris KC, Harcourt BE, Trounce IA, Robb PM, Laskowski A, McGee SL, Genders AJ, Walder K, Drew BG, Gregorevic P, Qian H, Thomas MC, Jerums G, Macisaac RJ, Skene A, Power DA, Ekinci EI, Wijeyeratne XW, Gallo LA, Herman-Edelstein M, Ryan MT, Cooper ME, Thorburn DR, Forbes JM.

Diabetes. 2016 Apr;65(4):1085-98. doi: 10.2337/db15-0864. Epub 2016 Jan 28.


Targeting Mitochondria and Reactive Oxygen Species-Driven Pathogenesis in Diabetic Nephropathy.

Lindblom R, Higgins G, Coughlan M, de Haan JB.

Rev Diabet Stud. 2015 Spring-Summer;12(1-2):134-56. doi: 10.1900/RDS.2015.12.134. Epub 2015 Aug 10. Review.


Noncollinear Polarization Gating of Attosecond Pulse Trains in the Relativistic Regime.

Yeung M, Bierbach J, Eckner E, Rykovanov S, Kuschel S, Sävert A, Förster M, Rödel C, Paulus GG, Cousens S, Coughlan M, Dromey B, Zepf M.

Phys Rev Lett. 2015 Nov 6;115(19):193903. doi: 10.1103/PhysRevLett.115.193903. Epub 2015 Nov 4.


Effect of diet-derived advanced glycation end products on inflammation.

Kellow NJ, Coughlan MT.

Nutr Rev. 2015 Nov;73(11):737-59. doi: 10.1093/nutrit/nuv030. Epub 2015 Sep 15. Review.


Can Targeting the Incretin Pathway Dampen RAGE-Mediated Events in Diabetic Nephropathy?

Sourris KC, Yao H, Jerums G, Cooper ME, Ekinci EI, Coughlan MT.

Curr Drug Targets. 2016;17(11):1252-64. Review.


A Northern contaminant mixture impairs pancreas function in obese and lean JCR rats and inhibits insulin secretion in MIN6 cells.

Mailloux R, Fu A, Florian M, Petrov I, Chen Q, Coughlan MC, Laziyan M, Yan J, Caldwell D, Patry D, Lalande M, Wang GS, Willmore W, Jin X.

Toxicology. 2015 Aug 6;334:81-93. doi: 10.1016/j.tox.2015.06.001. Epub 2015 Jun 9.


Traditional fire-use, landscape transition, and the legacies of social theory past.

Coughlan MR.

Ambio. 2015 Dec;44(8):705-17. doi: 10.1007/s13280-015-0643-y. Epub 2015 Jun 3. Review.


The use of FDG-PET in diffuse large B cell lymphoma (DLBCL): predicting outcome following first line therapy.

Coughlan M, Elstrom R.

Cancer Imaging. 2014 Nov 29;14:34. doi: 10.1186/s40644-014-0034-9. Review.


Nox-4 deletion reduces oxidative stress and injury by PKC-α-associated mechanisms in diabetic nephropathy.

Thallas-Bonke V, Jha JC, Gray SP, Barit D, Haller H, Schmidt HH, Coughlan MT, Cooper ME, Forbes JM, Jandeleit-Dahm KA.

Physiol Rep. 2014 Nov 3;2(11). pii: e12192. doi: 10.14814/phy2.12192. Print 2014 Nov 1.


Exposure to a northern contaminant mixture (NCM) alters hepatic energy and lipid metabolism exacerbating hepatic steatosis in obese JCR rats.

Mailloux RJ, Florian M, Chen Q, Yan J, Petrov I, Coughlan MC, Laziyan M, Caldwell D, Lalande M, Patry D, Gagnon C, Sarafin K, Truong J, Chan HM, Ratnayake N, Li N, Willmore WG, Jin X.

PLoS One. 2014 Sep 15;9(9):e106832. doi: 10.1371/journal.pone.0106832. eCollection 2014.


Ramipril inhibits AGE-RAGE-induced matrix metalloproteinase-2 activation in experimental diabetic nephropathy.

Fukami K, Yamagishi S, Coughlan MT, Harcourt BE, Kantharidis P, Thallas-Bonke V, Okuda S, Cooper ME, Forbes JM.

Diabetol Metab Syndr. 2014 Aug 13;6(1):86. doi: 10.1186/1758-5996-6-86. eCollection 2014.


A healthy regard for the legal system.

Coughlan M.

Nurs Stand. 2014 Aug 5;28(48):64-5. doi: 10.7748/ns.28.48.64.s52. No abstract available.


Mitochondrial dysfunction and mitophagy: the beginning and end to diabetic nephropathy?

Higgins GC, Coughlan MT.

Br J Pharmacol. 2014 Apr;171(8):1917-42. doi: 10.1111/bph.12503. Review.


Metabolic benefits of dietary prebiotics in human subjects: a systematic review of randomised controlled trials.

Kellow NJ, Coughlan MT, Reid CM.

Br J Nutr. 2014 Apr 14;111(7):1147-61. doi: 10.1017/S0007114513003607. Epub 2013 Nov 13. Review.


Advanced glycation end products (AGEs) are cross-sectionally associated with insulin secretion in healthy subjects.

Forbes JM, Sourris KC, de Courten MP, Dougherty SL, Chand V, Lyons JG, Bertovic D, Coughlan MT, Schlaich MP, Soldatos G, Cooper ME, Straznicky NE, Kingwell BA, de Courten B.

Amino Acids. 2014 Feb;46(2):321-6. doi: 10.1007/s00726-013-1542-9. Epub 2013 Jul 6.


Finding meaning behind meaningful use. Physicians discuss their experiences in obtaining government incentives for using technology.

Coughlan MM, Ellis GG Jr, Garner A, Goodman DS, McClintock MB.

Med Econ. 2012 Nov 25;89(22):41-2, 44-6. No abstract available.


Northern contaminant mixtures induced morphological and functional changes in human coronary artery endothelial cells under culture conditions typifying high fat/sugar diet and ethanol exposure.

Florian M, Yan J, Ulhaq S, Coughlan M, Laziyan M, Willmore W, Jin X.

Toxicology. 2013 Nov 16;313(2-3):103-12. doi: 10.1016/j.tox.2013.01.018. Epub 2013 Feb 4.


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