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Items: 46

1.

Correction: Liver kinase B1 expression promotes phosphatase activity and abrogation of receptor tyrosine kinase phosphorylation in human cancer cells.

Okon IS, Coughlan KA, Zou MH.

J Biol Chem. 2019 Aug 16;294(33):12555. doi: 10.1074/jbc.AAC119.010208. No abstract available.

2.

Vascular regression precedes motor neuron loss in the FUS (1-359) ALS mouse model.

Crivello M, Hogg MC, Jirström E, Halang L, Woods I, Rayner M, Coughlan KS, Lewandowski SA, Prehn JHM.

Dis Model Mech. 2019 Aug 13;12(8). pii: dmm040238. doi: 10.1242/dmm.040238.

3.

mRNA Therapy Improves Metabolic and Behavioral Abnormalities in a Murine Model of Citrin Deficiency.

Cao J, An D, Galduroz M, Zhuo J, Liang S, Eybye M, Frassetto A, Kuroda E, Funahashi A, Santana J, Mihai C, Benenato KE, Kumarasinghe ES, Sabnis S, Salerno T, Coughlan K, Miracco EJ, Levy B, Besin G, Schultz J, Lukacs C, Guey L, Finn P, Furukawa T, Giangrande PH, Saheki T, Martini PGV.

Mol Ther. 2019 Jul 3;27(7):1242-1251. doi: 10.1016/j.ymthe.2019.04.017. Epub 2019 Apr 23.

PMID:
31056400
4.

Pleiotropic activity of systemically delivered angiogenin in the SOD1G93A mouse model.

Crivello M, O'Riordan SL, Woods I, Cannon S, Halang L, Coughlan KS, Hogg MC, Lewandowski SA, Prehn JHM.

Neuropharmacology. 2018 May 1;133:503-511. doi: 10.1016/j.neuropharm.2018.02.022. Epub 2018 Feb 25.

PMID:
29486168
5.

Riluzole does not improve lifespan or motor function in three ALS mouse models.

Hogg MC, Halang L, Woods I, Coughlan KS, Prehn JHM.

Amyotroph Lateral Scler Frontotemporal Degener. 2018 Aug;19(5-6):438-445. doi: 10.1080/21678421.2017.1407796. Epub 2017 Dec 8.

PMID:
29221425
6.

The effects of troglitazone on AMPK in HepG2 cells.

Allen KM, Coughlan KA, Mahmood FN, Valentine RJ, Ruderman NB, Saha AK.

Arch Biochem Biophys. 2017 Jun 1;623-624:49-57. doi: 10.1016/j.abb.2017.05.010. Epub 2017 May 16.

PMID:
28526426
7.

Mortality Reduction for Fever, Hyperglycemia, and Swallowing Nurse-Initiated Stroke Intervention: QASC Trial (Quality in Acute Stroke Care) Follow-Up.

Middleton S, Coughlan K, Mnatzaganian G, Low Choy N, Dale S, Jammali-Blasi A, Levi C, Grimshaw JM, Ward J, Cadilhac DA, McElduff P, Hiller JE, D'Este C.

Stroke. 2017 May;48(5):1331-1336. doi: 10.1161/STROKEAHA.116.016038. Epub 2017 Apr 7.

PMID:
28389609
8.

Deletion of endothelial cell-specific liver kinase B1 increases angiogenesis and tumor growth via vascular endothelial growth factor.

Zhang W, Ding Y, Zhang C, Lu Q, Liu Z, Coughlan K, Okon I, Zou MH.

Oncogene. 2017 Jul 27;36(30):4277-4287. doi: 10.1038/onc.2017.61. Epub 2017 Mar 27.

9.
10.

PKD1 Inhibits AMPKα2 through Phosphorylation of Serine 491 and Impairs Insulin Signaling in Skeletal Muscle Cells.

Coughlan KA, Valentine RJ, Sudit BS, Allen K, Dagon Y, Kahn BB, Ruderman NB, Saha AK.

J Biol Chem. 2016 Mar 11;291(11):5664-75. doi: 10.1074/jbc.M115.696849. Epub 2016 Jan 21.

11.

Aberrant NRP-1 expression serves as predicator of metastatic endometrial and lung cancers.

Okon IS, Ding Y, Coughlan KA, Wang Q, Song P, Benbrook DM, Zou MH.

Oncotarget. 2016 Feb 16;7(7):7970-8. doi: 10.18632/oncotarget.6699.

12.

Nutrient Excess and AMPK Downregulation in Incubated Skeletal Muscle and Muscle of Glucose Infused Rats.

Coughlan KA, Balon TW, Valentine RJ, Petrocelli R, Schultz V, Brandon A, Cooney GJ, Kraegen EW, Ruderman NB, Saha AK.

PLoS One. 2015 May 21;10(5):e0127388. doi: 10.1371/journal.pone.0127388. eCollection 2015.

13.

Gefitinib-mediated reactive oxygen specie (ROS) instigates mitochondrial dysfunction and drug resistance in lung cancer cells.

Okon IS, Coughlan KA, Zhang M, Wang Q, Zou MH.

J Biol Chem. 2015 Apr 3;290(14):9101-10. doi: 10.1074/jbc.M114.631580. Epub 2015 Feb 13.

14.

"Preconditioning" with latrepirdine, an adenosine 5'-monophosphate-activated protein kinase activator, delays amyotrophic lateral sclerosis progression in SOD1(G93A) mice.

Coughlan KS, Mitchem MR, Hogg MC, Prehn JH.

Neurobiol Aging. 2015 Feb;36(2):1140-50. doi: 10.1016/j.neurobiolaging.2014.09.022. Epub 2014 Sep 26.

PMID:
25443289
15.

AMPKα1 deficiency promotes cellular proliferation and DNA damage via p21 reduction in mouse embryonic fibroblasts.

Xu H, Zhou Y, Coughlan KA, Ding Y, Wang S, Wu Y, Song P, Zou MH.

Biochim Biophys Acta. 2015 Jan;1853(1):65-73. doi: 10.1016/j.bbamcr.2014.10.002. Epub 2014 Oct 13.

16.

Crucial involvement of xanthine oxidase in the intracellular signalling networks associated with human myeloid cell function.

Abooali M, Lall GS, Coughlan K, Lall HS, Gibbs BF, Sumbayev VV.

Sci Rep. 2014 Sep 9;4:6307. doi: 10.1038/srep06307.

17.

Protein kinase LKB1 promotes RAB7-mediated neuropilin-1 degradation to inhibit angiogenesis.

Okon IS, Coughlan KA, Zhang C, Moriasi C, Ding Y, Song P, Zhang W, Li G, Zou MH.

J Clin Invest. 2014 Oct;124(10):4590-602. doi: 10.1172/JCI75371. Epub 2014 Sep 2.

18.

Insulin inhibits AMPK activity and phosphorylates AMPK Ser⁴⁸⁵/⁴⁹¹ through Akt in hepatocytes, myotubes and incubated rat skeletal muscle.

Valentine RJ, Coughlan KA, Ruderman NB, Saha AK.

Arch Biochem Biophys. 2014 Nov 15;562:62-9. doi: 10.1016/j.abb.2014.08.013. Epub 2014 Aug 27.

19.

AMPK activation: a therapeutic target for type 2 diabetes?

Coughlan KA, Valentine RJ, Ruderman NB, Saha AK.

Diabetes Metab Syndr Obes. 2014 Jun 24;7:241-53. doi: 10.2147/DMSO.S43731. eCollection 2014. Review.

20.

The BCL-2 family protein Bid is critical for pro-inflammatory signaling in astrocytes.

König HG, Coughlan KS, Kinsella S, Breen BA, Prehn JH.

Neurobiol Dis. 2014 Oct;70:99-107. doi: 10.1016/j.nbd.2014.06.008. Epub 2014 Jun 21.

PMID:
24956542
21.

Are suspected stroke patients identified by paramedics transported to appropriate stroke centres in Victoria, Australia?

Bray JE, Coughlan K, Mosley I, Barger B, Bladin C.

Intern Med J. 2014 May;44(5):515-8. doi: 10.1111/imj.12382.

PMID:
24816313
22.

Liver kinase B1 expression promotes phosphatase activity and abrogation of receptor tyrosine kinase phosphorylation in human cancer cells.

Okon IS, Coughlan KA, Zou MH.

J Biol Chem. 2014 Jan 17;289(3):1639-48. doi: 10.1074/jbc.M113.500934. Epub 2013 Nov 27. Erratum in: J Biol Chem. 2019 Aug 16;294(33):12555.

23.

Adenosine monophosphate-activated protein kinase-α2 deficiency promotes vascular smooth muscle cell migration via S-phase kinase-associated protein 2 upregulation and E-cadherin downregulation.

Song P, Zhou Y, Coughlan KA, Dai X, Xu H, Viollet B, Zou MH.

Arterioscler Thromb Vasc Biol. 2013 Dec;33(12):2800-9. doi: 10.1161/ATVBAHA.113.301869. Epub 2013 Oct 10. Erratum in: Arterioscler Thromb Vasc Biol. 2014 Oct;34(10):e23.

24.

Nutrient Excess in AMPK Downregulation and Insulin Resistance.

Coughlan KA, Valentine RJ, Ruderman NB, Saha AK.

J Endocrinol Diabetes Obes. 2013 Jul-Sep;1(1):1008.

25.

Structure-activity relationship of memapsin 2: implications on physiological functions and Alzheimer's disease.

Li X, Hong L, Coughlan K, Wang L, Cao L, Tang J.

Acta Biochim Biophys Sin (Shanghai). 2013 Aug;45(8):613-21. doi: 10.1093/abbs/gmt050. Epub 2013 May 15. Review.

26.

Expression and processing of fluorescent fusion proteins of amyloid precursor protein (APP).

Coughlan K, Huang X, He X, Chung CH, Li G, Tang J.

Biochim Biophys Acta. 2013 Jun;1833(6):1562-71. doi: 10.1016/j.bbamcr.2013.03.003. Epub 2013 Mar 19.

27.

The yin-yang of DNA damage response: roles in tumorigenesis and cellular senescence.

Li X, Xu H, Xu C, Lin M, Song X, Yi F, Feng Y, Coughlan KA, Cho WC, Kim SS, Cao L.

Int J Mol Sci. 2013 Jan 25;14(2):2431-48. doi: 10.3390/ijms14022431.

28.

Acidotoxicity and acid-sensing ion channels contribute to motoneuron degeneration.

Behan AT, Breen B, Hogg M, Woods I, Coughlan K, Mitchem M, Prehn JH.

Cell Death Differ. 2013 Apr;20(4):589-98. doi: 10.1038/cdd.2012.158. Epub 2013 Jan 11. Retraction in: Cell Death Differ. 2014 Feb;21(2):344.

29.

Inhibition of AMP-activated protein kinase accentuates lipopolysaccharide-induced lung endothelial barrier dysfunction and lung injury in vivo.

Xing J, Wang Q, Coughlan K, Viollet B, Moriasi C, Zou MH.

Am J Pathol. 2013 Mar;182(3):1021-30. doi: 10.1016/j.ajpath.2012.11.022. Epub 2013 Jan 7.

30.

Mitofusins 1 and 2 are essential for postnatal metabolic remodeling in heart.

Papanicolaou KN, Kikuchi R, Ngoh GA, Coughlan KA, Dominguez I, Stanley WC, Walsh K.

Circ Res. 2012 Sep 28;111(8):1012-26. Epub 2012 Aug 17.

31.

Motoneurons secrete angiogenin to induce RNA cleavage in astroglia.

Skorupa A, King MA, Aparicio IM, Dussmann H, Coughlan K, Breen B, Kieran D, Concannon CG, Marin P, Prehn JH.

J Neurosci. 2012 Apr 11;32(15):5024-38. doi: 10.1523/JNEUROSCI.6366-11.2012.

32.

Pharmacological inhibition of Kv1.3 fails to modulate insulin sensitivity in diabetic mice or human insulin-sensitive tissues.

Straub SV, Perez SM, Tan B, Coughlan KA, Trebino CE, Cosgrove P, Buxton JM, Kreeger JM, Jackson VM.

Am J Physiol Endocrinol Metab. 2011 Aug;301(2):E380-90. doi: 10.1152/ajpendo.00076.2011. Epub 2011 May 17.

33.

Dysfunctional mitochondria contain endogenous high-affinity human Toll-like receptor 4 (TLR4) ligands and induce TLR4-mediated inflammatory reactions.

Nicholas SA, Coughlan K, Yasinska I, Lall GS, Gibbs BF, Calzolai L, Sumbayev VV.

Int J Biochem Cell Biol. 2011 Apr;43(4):674-81. doi: 10.1016/j.biocel.2011.01.012. Epub 2011 Jan 22.

PMID:
21262374
34.

Continence management in acute stroke: a survey of current practices in Australia.

Jordan LA, Mackey E, Coughlan K, Wyer M, Allnutt N, Middleton S.

J Adv Nurs. 2011 Jan;67(1):94-104. doi: 10.1111/j.1365-2648.2010.05480.x. Epub 2010 Oct 24.

PMID:
20969615
35.

The involvement of sphingosine kinase 1 in LPS-induced Toll-like receptor 4-mediated accumulation of HIF-1α protein, activation of ASK1 and production of the pro-inflammatory cytokine IL-6.

Pchejetski D, Nunes J, Coughlan K, Lall H, Pitson SM, Waxman J, Sumbayev VV.

Immunol Cell Biol. 2011 Feb;89(2):268-74. doi: 10.1038/icb.2010.91. Epub 2010 Jul 27.

PMID:
20661259
36.

Paramedic diagnosis of stroke: examining long-term use of the Melbourne Ambulance Stroke Screen (MASS) in the field.

Bray JE, Coughlan K, Barger B, Bladin C.

Stroke. 2010 Jul;41(7):1363-6. doi: 10.1161/STROKEAHA.109.571836. Epub 2010 Jun 10.

PMID:
20538702
37.

Methicillin-resistant Staphylococcus aureus in resident animals of a long-term care facility.

Coughlan K, Olsen KE, Boxrud D, Bender JB.

Zoonoses Public Health. 2010 May;57(3):220-6. doi: 10.1111/j.1863-2378.2009.01302.x. Epub 2009 Dec 23.

PMID:
20042067
38.

Apoptosis signal-regulating kinase 1 (ASK1) and HIF-1alpha protein are essential factors for nitric oxide-dependent accumulation of p53 in THP-1 human myeloid macrophages.

Jawahir M, Nicholas SA, Coughlan K, Sumbayev VV.

Apoptosis. 2008 Dec;13(12):1410-6. doi: 10.1007/s10495-008-0267-9.

PMID:
18841476
39.

Lessons learnt in implementation of ABCD score in an emergency department.

Bray J, Bladin C, Coughlan K, Patil A.

Stroke. 2008 Jul;39(7):e111; author reply e112. doi: 10.1161/STROKEAHA.107.518431. Epub 2008 May 15. No abstract available.

PMID:
18483417
40.

HIF-1alpha protein is an essential factor for protection of myeloid cells against LPS-induced depletion of ATP and apoptosis that supports Toll-like receptor 4-mediated production of IL-6.

Lall H, Coughlan K, Sumbayev VV.

Mol Immunol. 2008 Jun;45(11):3045-9. doi: 10.1016/j.molimm.2008.03.014. Epub 2008 May 6.

PMID:
18462799
42.
43.

Exogenous TGF-beta1 promotes stromal development in the heifer mammary gland.

Musters S, Coughlan K, McFadden T, Maple R, Mulvey T, Plaut K.

J Dairy Sci. 2004 Apr;87(4):896-904.

44.

Patellofemoral contact forces and pressures during intramedullary tibial nailing.

Devitt AT, Coughlan KA, Ward T, McCormack D, Mulcahy D, Felle P, McElwain JP.

Int Orthop. 1998;22(2):92-6.

45.

A new trichrome-blue stain for detection of microsporidial species in urine, stool, and nasopharyngeal specimens.

Ryan NJ, Sutherland G, Coughlan K, Globan M, Doultree J, Marshall J, Baird RW, Pedersen J, Dwyer B.

J Clin Microbiol. 1993 Dec;31(12):3264-9.

46.

Women partners of Vietnam vets.

Coughlan K, Parkin C.

J Psychosoc Nurs Ment Health Serv. 1987 Oct;25(10):25-7. No abstract available.

PMID:
3681775

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