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Items: 9


Human T cell response to CD1a and contact dermatitis allergens in botanical extracts and commercial skin care products.

Nicolai S, Wegrecki M, Cheng TY, Bourgeois EA, Cotton RN, Mayfield JA, Monnot GC, Le Nours J, Van Rhijn I, Rossjohn J, Moody DB, de Jong A.

Sci Immunol. 2020 Jan 3;5(43). pii: eaax5430. doi: 10.1126/sciimmunol.aax5430. Epub 2020 Jan 3.


Mycobacterium tuberculosis releases an antacid that remodels phagosomes.

Buter J, Cheng TY, Ghanem M, Grootemaat AE, Raman S, Feng X, Plantijn AR, Ennis T, Wang J, Cotton RN, Layre E, Ramnarine AK, Mayfield JA, Young DC, Jezek Martinot A, Siddiqi N, Wakabayashi S, Botella H, Calderon R, Murray M, Ehrt S, Snider BB, Reed MB, Oldfield E, Tan S, Rubin EJ, Behr MA, van der Wel NN, Minnaard AJ, Moody DB.

Nat Chem Biol. 2019 Sep;15(9):889-899. doi: 10.1038/s41589-019-0336-0. Epub 2019 Aug 19.


Lipids hide or step aside for CD1-autoreactive T cell receptors.

Cotton RN, Shahine A, Rossjohn J, Moody DB.

Curr Opin Immunol. 2018 Jun;52:93-99. doi: 10.1016/j.coi.2018.04.013. Epub 2018 May 5. Review.


Four pathways of CD1 antigen presentation to T cells.

Moody DB, Cotton RN.

Curr Opin Immunol. 2017 Jun;46:127-133. doi: 10.1016/j.coi.2017.07.013. Epub 2017 Jul 28. Review.


Total Synthesis of Mycobacterium tuberculosis Dideoxymycobactin-838 and Stereoisomers: Diverse CD1a-Restricted T Cells Display a Common Hierarchy of Lipopeptide Recognition.

Cheng JM, Liu L, Pellicci DG, Reddiex SJ, Cotton RN, Cheng TY, Young DC, Van Rhijn I, Moody DB, Rossjohn J, Fairlie DP, Godfrey DI, Williams SJ.

Chemistry. 2017 Jan 31;23(7):1694-1701. doi: 10.1002/chem.201605287. Epub 2017 Jan 18.


Microfilariae of Brugia malayi Inhibit the mTOR Pathway and Induce Autophagy in Human Dendritic Cells.

Narasimhan PB, Bennuru S, Meng Z, Cotton RN, Elliott KR, Ganesan S, McDonald-Fleming R, Veenstra TD, Nutman TB, Tolouei Semnani R.

Infect Immun. 2016 Aug 19;84(9):2463-72. doi: 10.1128/IAI.00174-16. Print 2016 Sep.


Brugia malayi infective larvae fail to activate Langerhans cells and dermal dendritic cells in human skin.

Cotton RN, McDonald-Fleming R, Boyd A, Spates K, Nutman TB, Tolouei Semnani R.

Parasite Immunol. 2015 Feb;37(2):79-91. doi: 10.1111/pim.12169.


Human dendritic cells exhibit a pronounced type I IFN signature following Leishmania major infection that is required for IL-12 induction.

Favila MA, Geraci NS, Zeng E, Harker B, Condon D, Cotton RN, Jayakumar A, Tripathi V, McDowell MA.

J Immunol. 2014 Jun 15;192(12):5863-72. doi: 10.4049/jimmunol.1203230. Epub 2014 May 7.


Leishmania major inhibits IL-12 in macrophages by signalling through CR3 (CD11b/CD18) and down-regulation of ETS-mediated transcription.

Ricardo-Carter C, Favila M, Polando RE, Cotton RN, Bogard Horner K, Condon D, Ballhorn W, Whitcomb JP, Yadav M, Geister RL, Schorey JS, McDowell MA.

Parasite Immunol. 2013 Dec;35(12):409-20. doi: 10.1111/pim.12049.

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