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Abacavir exposure in children co-treated for tuberculosis with rifampicin and super-boosted lopinavir-ritonavir.

Rabie H, Tikiso T, Lee J, Fairlie L, Strehlau R, Bobat R, Liberty A, McIlleron H, Andrieux-Meyer I, Cotton M, Lallemant M, Denti P.

Antimicrob Agents Chemother. 2020 Feb 18. pii: AAC.01923-19. doi: 10.1128/AAC.01923-19. [Epub ahead of print]


Effect of HIV-exposure and timing of antiretroviral treatment initiation in children living with HIV on antibody persistence and memory responses to Haemophilus influenzae type b and pneumococcal polysaccharide-protein conjugate vaccines.

Madhi SA, Izu A, Violari A, Cotton MF, Jean-Philippe P, Otwombe K, Adrian PV; CIPRA 4 team.

Vaccine. 2020 Feb 15. pii: S0264-410X(20)30223-1. doi: 10.1016/j.vaccine.2020.02.026. [Epub ahead of print]


High-dose rifapentine with or without moxifloxacin for shortening treatment of pulmonary tuberculosis: Study protocol for TBTC study 31/ACTG A5349 phase 3 clinical trial.

Dorman SE, Nahid P, Kurbatova EV, Goldberg SV, Bozeman L, Burman WJ, Chang KC, Chen M, Cotton M, Dooley KE, Engle M, Feng PJ, Fletcher CV, Ha P, Heilig CM, Johnson JL, Lessem E, Metchock B, Miro JM, Nhung NV, Pettit AC, Phillips PPJ, Podany AT, Purfield AE, Robergeau K, Samaneka W, Scott NA, Sizemore E, Vernon A, Weiner M, Swindells S, Chaisson RE; AIDS Clinical Trials Group and the Tuberculosis Trials Consortium.

Contemp Clin Trials. 2020 Jan 22;90:105938. doi: 10.1016/j.cct.2020.105938. [Epub ahead of print]


Intermittent Ethanol Access Increases Sensitivity to Social Defeat Stress.

Nennig SE, Fulenwider HD, Eskew JE, Whiting KE, Cotton MR, McGinty GE, Solomon MG, Schank JR.

Alcohol Clin Exp Res. 2020 Jan 19. doi: 10.1111/acer.14278. [Epub ahead of print]


Extending a hand of greeting to Latin America.

Cotton M.

Trop Doct. 2020 Jan;50(1):1-2. doi: 10.1177/0049475519895333. No abstract available.


HIV outbreak in children in Pakistan: localised or more widespread?

Cotton MF, Rabie H.

Lancet Infect Dis. 2019 Dec 19. pii: S1473-3099(19)30746-7. doi: 10.1016/S1473-3099(19)30746-7. [Epub ahead of print] No abstract available.


African Multi-Site 2-Year Neuropsychological Study of School-Age Children Perinatally Infected, Exposed, and Unexposed to Human Immunodeficiency Virus.

Boivin MJ, Chernoff M, Fairlie L, Laughton B, Zimmer B, Joyce C, Barlow-Mosha L, Bwakura-Dangarembizi M, Vhembo T, Ratswana M, Kamthunzi P, McCarthy K, Familiar-Lopez I, Jean-Philippe P, Coetzee J, Abrahams N, Gous H, Violari A, Cotton MF, Palumbo PE.

Clin Infect Dis. 2019 Dec 18. pii: ciz1088. doi: 10.1093/cid/ciz1088. [Epub ahead of print]


Intact HIV Proviruses Persist in Children Seven to Nine Years after Initiation of Antiretroviral Therapy in the First Year of Life.

Katusiime MG, Halvas EK, Wright I, Joseph K, Bale MJ, Kirby-McCullough B, Engelbrecht S, Shao W, Hu WS, Cotton MF, Mellors JW, Kearney MF, van Zyl GU.

J Virol. 2020 Jan 31;94(4). pii: e01519-19. doi: 10.1128/JVI.01519-19. Print 2020 Jan 31.


Neurodevelopment at 11 months after starting antiretroviral therapy within 3 weeks of life.

Laughton B, Naidoo S, Dobbels EFMT, Boivin MJ, van Rensburg AJ, Glashoff RH, van Zyl GU, Kruger M, Cotton MF.

South Afr J HIV Med. 2019 Oct 30;20(1):1008. doi: 10.4102/sajhivmed.v20i1.1008. eCollection 2019.


Earlier Antiretroviral Therapy Initiation and Decreasing Mortality Among HIV-infected Infants Initiating Antiretroviral Therapy Within 3 Months of Age in South Africa, 2006-2017.

Iyun V, Technau KG, Eley B, Rabie H, Boulle A, Fatti G, Egger M, Tanser F, Wood R, Fairlie L, Cotton MF, Davies MA.

Pediatr Infect Dis J. 2020 Feb;39(2):127-133. doi: 10.1097/INF.0000000000002516.


Pharmacokinetics and safety of a raltegravir-containing regimen in HIV-infected children aged 2-12 years on rifampicin for tuberculosis.

Meyers T, Samson P, Acosta EP, Moye J, Townley E, Bradford S, Marillo L, Denson K, Hovind L, Sise T, Teppler H, Mathiba SR, Masenya M, Hesseling A, Cotton MF, Krogstad P; IMPAACT P1101 Team.

AIDS. 2019 Nov 15;33(14):2197-2203. doi: 10.1097/QAD.0000000000002369.


Disclosure of human immunodeficiency virus status to children in South Africa: A comprehensive analysis.

van Elsland SL, Peters RPH, Grobbelaar C, Ketelo P, Kok MO, Cotton MF, van Furth AM.

South Afr J HIV Med. 2019 Aug 22;20(1):884. doi: 10.4102/sajhivmed.v20i1.884. eCollection 2019.


Essential metrics for high-quality reporting of neonatal sepsis research in low-resource settings.

Rabie H, Cotton M, Dramowski A.

Lancet Infect Dis. 2019 Nov;19(11):1155-1157. doi: 10.1016/S1473-3099(19)30495-5. Epub 2019 Sep 12. No abstract available.


Ebola is back.

Cotton M.

Trop Doct. 2019 Oct;49(4):255. doi: 10.1177/0049475519876758. No abstract available.


HIV-1 DNA decay is faster in children who initiate ART shortly after birth than later.

Veldsman KA, Janse van Rensburg A, Isaacs S, Naidoo S, Laughton B, Lombard C, Cotton MF, Mellors JW, van Zyl GU.

J Int AIDS Soc. 2019 Aug;22(8):e25368. doi: 10.1002/jia2.25368.


Multisystem impairment in South African adolescents with Perinatally acquired HIV on antiretroviral therapy (ART).

Frigati LJ, Brown K, Mahtab S, Githinji L, Gray D, Zühlke L, Nourse P, Stein DJ, Hoare J, Cotton MF, Myer L, Zar HJ.

J Int AIDS Soc. 2019 Aug;22(8):e25386. doi: 10.1002/jia2.25386.


Neurodevelopmental and behavioural outcomes of HIV-exposed uninfected and HIV-unexposed children at 2-3 years of age in Cape Town, South Africa.

Springer PE, Slogrove AL, Kidd M, Kalk E, Bettinger JA, Esser MM, Cotton MF, Zunza M, Molteno CD, Kruger M.

AIDS Care. 2019 Jul 7:1-9. doi: 10.1080/09540121.2019.1637506. [Epub ahead of print]


A prospective study of the immune reconstitution inflammatory syndrome (IRIS) in HIV-infected children from high prevalence countries.

Cotton MF, Rabie H, Nemes E, Mujuru H, Bobat R, Njau B, Violari A, Mave V, Mitchell C, Oleske J, Zimmer B, Varghese G, Pahwa S; P1073 team.

PLoS One. 2019 Jul 1;14(7):e0211155. doi: 10.1371/journal.pone.0211155. eCollection 2019.


Preoperative Warming Reduces Intraoperative Hypothermia in Total Joint Arthroplasty Patients.

Kay AB, Klavas DM, Hirase T, Cotton MO, Lambert BS, Incavo SJ.

J Am Acad Orthop Surg. 2019 Jun 14. doi: 10.5435/JAAOS-D-19-00041. [Epub ahead of print]


What Will It Take to Implement Targeted HIV Testing at Birth?

Cotton MF, Rabie H.

Pediatrics. 2019 Jun;143(6). pii: e20190913. doi: 10.1542/peds.2019-0913. Epub 2019 May 17. No abstract available.


Is point-of-care early infant HIV diagnosis sustainable?

Cotton MF, Rabie H.

Lancet HIV. 2019 Jun;6(6):e344-e345. doi: 10.1016/S2352-3018(19)30078-5. Epub 2019 Apr 12. No abstract available.


Doctors and Torture.

Cotton M.

Trop Doct. 2019 Apr;49(2):73-74. doi: 10.1177/0049475519841485. Epub 2019 Mar 27. No abstract available.


What Should We Do When HIV-positive Children Fail First-line Combination Antiretroviral Therapy? A Comparison of 4 ART Management Strategies.

Patten G, Schomaker M, Davies MA, Rabie H, van Zyl G, Technau K, Eley B, Boulle A, Van Dyke RB, Patel K, Sipambo N, Wood R, Tanser F, Giddy J, Cotton M, Nuttall J, Essack G, Karalius B, Seage G, Sawry S, Egger M, Fairlie L; for IeDEA Southern Africa.

Pediatr Infect Dis J. 2019 Apr;38(4):400-405. doi: 10.1097/INF.0000000000002156.


Dirty war practice targeting medical care.

Cotton M.

Trop Doct. 2019 Jan;49(1):1-2. doi: 10.1177/0049475518822031. No abstract available.


Should efavirenz be used in children and, if so, how?

Cotton MF, Laughton B, Rabie H.

Lancet HIV. 2019 Apr;6(4):e210-e211. doi: 10.1016/S2352-3018(18)30337-0. Epub 2019 Feb 12. No abstract available.


Operating Room Attire.

Cotton M.

J Am Coll Surg. 2019 Feb;228(2):209-210. doi: 10.1016/j.jamcollsurg.2018.11.001. No abstract available.


A child with perinatal HIV infection and long-term sustained virological control following antiretroviral treatment cessation.

Violari A, Cotton MF, Kuhn L, Schramm DB, Paximadis M, Loubser S, Shalekoff S, Da Costa Dias B, Otwombe K, Liberty A, McIntyre J, Babiker A, Gibb D, Tiemessen CT.

Nat Commun. 2019 Jan 24;10(1):412. doi: 10.1038/s41467-019-08311-0.


Human Immunodeficiency Virus-exposed Uninfected Infants: Surviving and Thriving or Overlooked by Success?

Slogrove AL, Powis KM, Cotton MF.

Clin Infect Dis. 2019 May 30;68(12):2156-2158. doi: 10.1093/cid/ciy1056. No abstract available.


Lopinavir-ritonavir super-boosting in young HIV-infected children on rifampicin-based tuberculosis therapy compared with lopinavir-ritonavir without rifampicin: a pharmacokinetic modelling and clinical study.

Rabie H, Denti P, Lee J, Masango M, Coovadia A, Pillay S, Liberty A, Simon F, McIlleron H, Cotton MF, Lallemant M.

Lancet HIV. 2018 Dec 6. pii: S2352-3018(18)30293-5. doi: 10.1016/S2352-3018(18)30293-5. [Epub ahead of print]


Conversation on the Ebola outbreak in Sierra Leone with Sinead Walsh and Oliver Johnson.

Cotton M.

Trop Doct. 2018 Oct;48(4):259-260. doi: 10.1177/0049475518807006. No abstract available.


Measles Immunity at 4.5 Years of Age Following Vaccination at 9 and 15-18 Months of Age Among Human Immunodeficiency Virus (HIV)-infected, HIV-exposed-uninfected, and HIV-unexposed Children.

Mutsaerts EAML, Nunes MC, van Rijswijk MN, Klipstein-Grobusch K, Otwombe K, Cotton MF, Violari A, Madhi SA.

Clin Infect Dis. 2019 Aug 1;69(4):687-696. doi: 10.1093/cid/ciy964.


Effect of HIV exposure and timing of antiretroviral therapy initiation on immune memory responses to diphtheria, tetanus, whole cell pertussis and hepatitis B vaccines.

Simani OE, Izu A, Nunes MC, Violari A, Cotton MF, Van Niekerk N, Adrian PV, Madhi SA.

Expert Rev Vaccines. 2019 Jan;18(1):95-104. doi: 10.1080/14760584.2019.1547195. Epub 2018 Nov 19.


Vancomycin-resistant Enterococcus faecium Empyema in an Asplenic Patient.

Cotton MJ, Packer CD.

Cureus. 2018 Aug 29;10(8):e3227. doi: 10.7759/cureus.3227.


Considerations in evaluating infectious morbidity and mortality in HIV-exposed uninfected infants.

Slogrove AL, Powis KM, Bettinger JA, Cotton MF.

AIDS. 2018 Nov 28;32(18):2855-2856. doi: 10.1097/QAD.0000000000002049. No abstract available.


'Of Mice and Dementia': A filmed conversation on the use of animals in dementia research.

Tamagnini F, Cotton M, Goodall O, Harrison G, Jeynes C, Palombo F, Tomkow J, Tomkow T, Wedgwood K, Welsman J.

Dementia (London). 2018 Nov;17(8):1055-1063. doi: 10.1177/1471301218789560.


Diagnostic accuracy of the Molteno Adapted Scale for developmental delay in South African toddlers.

Honeth I, Laughton B, Springer PE, Cotton MF, Pretorius C.

Paediatr Int Child Health. 2019 May;39(2):132-138. doi: 10.1080/20469047.2018.1528754. Epub 2018 Oct 17.


Strong sex bias in elite control of paediatric HIV infection.

Vieira VA, Zuidewind P, Muenchhoff M, Roider J, Millar J, Clapson M, Van Zyl A, Shingadia D, Adland E, Athavale R, Grayson N, Ansari MA, Brander C, Guash CF, Naver L, Puthanakit T, Songtaweesin WN, Ananworanich J, Peluso D, Thomé B, Pinto J, Jooste P, Tudor-Williams G, Cotton MF, Goulder P.

AIDS. 2019 Jan 27;33(1):67-75. doi: 10.1097/QAD.0000000000002043. Erratum in: AIDS. 2019 Oct 1;33(12):1959.


Naive B Cell Output in HIV-Infected and HIV-Uninfected Children.

Payne H, Chain G, Adams S, Hunter P, Luckhurst N, Gilmour K, Lewis J, Babiker A, Cotton M, Violari A, Gibb D, Callard R, Klein N.

AIDS Res Hum Retroviruses. 2019 Jan;35(1):33-39. doi: 10.1089/AID.2018.0170. Epub 2018 Dec 26.


Prevalence of risk factors for chronic kidney disease in South African youth with perinatally acquired HIV.

Frigati L, Mahtab S, Nourse P, Ray P, Perrazzo S, Machemedze T, Agyei NA, Cotton M, Myer L, Zar H.

Pediatr Nephrol. 2019 Feb;34(2):313-318. doi: 10.1007/s00467-018-4080-6. Epub 2018 Sep 15.


Insulin Resistance in South African Youth Living with Perinatally Acquired HIV Receiving Antiretroviral Therapy.

Frigati LJ, Jao J, Mahtab S, Asafu Agyei NA, Cotton MF, Myer L, Zar HJ.

AIDS Res Hum Retroviruses. 2019 Jan;35(1):56-62. doi: 10.1089/AID.2018.0092. Epub 2018 Sep 25.


Output from the CIHR Canadian HIV Trials Network international postdoctoral fellowship for capacity building in HIV clinical trials.

Mbuagbaw L, Slogrove AL, Sas J, Lengwe Kunda J, Morfaw F, Mukonzo JK, Cao W, Ngomba-Kadima G, Zunza M, Ongolo-Zogo P, Nana PN, Cockcroft A, Andersson N, Sewankambo N, Cotton MF, Li T, Young T, Singer J, Routy JP, Ross CJ, Thin K, Thabane L, Anis AH.

HIV AIDS (Auckl). 2018 Aug 16;10:151-155. doi: 10.2147/HIV.S150107. eCollection 2018.


Can We Improve Stavudine's Safety Profile in Children? Pharmacokinetics of Intracellular Stavudine Triphosphate with Reduced Dosing.

Innes S, van der Laan L, Anderson PL, Cotton M, Denti P.

Antimicrob Agents Chemother. 2018 Oct 24;62(11). pii: e00761-18. doi: 10.1128/AAC.00761-18. Print 2018 Nov.


A treatment-support intervention evaluated in South African paediatric populations with HIV infection or tuberculous meningitis.

van Elsland SL, Peters RPH, Kok MO, van Toorn R, Springer P, Cotton MF, Grobbelaar CJ, Aarnoutse R, van Furth AM.

Trop Med Int Health. 2018 Oct;23(10):1129-1140. doi: 10.1111/tmi.13134. Epub 2018 Sep 3.


Paediatric ART Adherence in South Africa: A Comprehensive Analysis.

van Elsland SL, Peters RPH, Grobbelaar N, Ketelo P, Kok MO, Cotton MF, van Furth AM.

AIDS Behav. 2019 Feb;23(2):475-488. doi: 10.1007/s10461-018-2235-x.


Rampant infection & multi-resistance.

Cotton M.

Trop Doct. 2018 Jul;48(3):177-178. doi: 10.1177/0049475518782587. No abstract available.


Early Breastfeeding Cessation Among HIV-Infected and HIV-Uninfected Women in Western Cape Province, South Africa.

Zunza M, Esser M, Slogrove A, Bettinger JA, Machekano R, Cotton MF; Mother-Infant Health Study (MIHS) Project Steering Committee.

AIDS Behav. 2018 Jul;22(Suppl 1):114-120. doi: 10.1007/s10461-018-2208-0.


Loss of intraoperative neurological monitoring signals during flexed prone positioning on a hinged open frame during surgery for kyphoscoliosis correction: case report.

Graham RB, Cotton M, Koht A, Koski TR.

J Neurosurg Spine. 2018 Sep;29(3):339-343. doi: 10.3171/2018.1.SPINE17811. Epub 2018 Jun 22.


Perinatal HIV Infection or Exposure Is Associated With Low N-Acetylaspartate and Glutamate in Basal Ganglia at Age 9 but Not 7 Years.

Robertson FC, Holmes MJ, Cotton MF, Dobbels E, Little F, Laughton B, van der Kouwe AJW, Meintjes EM.

Front Hum Neurosci. 2018 May 7;12:145. doi: 10.3389/fnhum.2018.00145. eCollection 2018.


Five year neurodevelopment outcomes of perinatally HIV-infected children on early limited or deferred continuous antiretroviral therapy.

Laughton B, Cornell M, Kidd M, Springer PE, Dobbels EFM, Rensburg AJV, Otwombe K, Babiker A, Gibb DM, Violari A, Kruger M, Cotton MF.

J Int AIDS Soc. 2018 May;21(5):e25106. doi: 10.1002/jia2.25106.


Shorter treatment for minimal tuberculosis (TB) in children (SHINE): a study protocol for a randomised controlled trial.

Chabala C, Turkova A, Thomason MJ, Wobudeya E, Hissar S, Mave V, van der Zalm M, Palmer M, Kapasa M, Bhavani PK, Balaji S, Raichur PA, Demers AM, Hoddinott G, Owen-Powell E, Kinikar A, Musoke P, Mulenga V, Aarnoutse R, McIlleron H, Hesseling A, Crook AM, Cotton M, Gibb DM; SHINE trial team.

Trials. 2018 Apr 19;19(1):237. doi: 10.1186/s13063-018-2608-5.

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