Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 86


Transcriptional and genomic parallels between the monoxenous parasite Herpetomonas muscarum and Leishmania.

Sloan MA, Brooks K, Otto TD, Sanders MJ, Cotton JA, Ligoxygakis P.

PLoS Genet. 2019 Nov 11;15(11):e1008452. doi: 10.1371/journal.pgen.1008452. eCollection 2019 Nov.


Genomic and metabolomic polymorphism among experimentally selected paromomycin-resistant Leishmania donovani strains.

Shaw CD, Imamura H, Downing T, Blackburn G, Westrop GD, Cotton JA, Berriman M, Sanders M, Rijal S, Coombs GH, Dujardin JC, Carter KC.

Antimicrob Agents Chemother. 2019 Oct 28. pii: AAC.00904-19. doi: 10.1128/AAC.00904-19. [Epub ahead of print]


The global diversity of Haemonchus contortus is shaped by human intervention and climate.

Sallé G, Doyle SR, Cortet J, Cabaret J, Berriman M, Holroyd N, Cotton JA.

Nat Commun. 2019 Oct 22;10(1):4811. doi: 10.1038/s41467-019-12695-4.


Evaluation of DNA Extraction Methods on Individual Helminth Egg and Larval Stages for Whole-Genome Sequencing.

Doyle SR, Sankaranarayanan G, Allan F, Berger D, Jimenez Castro PD, Collins JB, Crellen T, Duque-Correa MA, Ellis P, Jaleta TG, Laing R, Maitland K, McCarthy C, Moundai T, Softley B, Thiele E, Ouakou PT, Tushabe JV, Webster JP, Weiss AJ, Lok J, Devaney E, Kaplan RM, Cotton JA, Berriman M, Holroyd N.

Front Genet. 2019 Sep 20;10:826. doi: 10.3389/fgene.2019.00826. eCollection 2019.


The confounding effects of high genetic diversity on the determination and interpretation of differential gene expression analysis in the parasitic nematode Haemonchus contortus.

Rezansoff AM, Laing R, Martinelli A, Stasiuk S, Redman E, Bartley D, Holroyd N, Devaney E, Sargison ND, Doyle S, Cotton JA, Gilleard JS.

Int J Parasitol. 2019 Oct;49(11):847-858. doi: 10.1016/j.ijpara.2019.05.012. Epub 2019 Sep 13.


Whole genome sequencing of experimental hybrids supports meiosis-like sexual recombination in Leishmania.

Inbar E, Shaik J, Iantorno SA, Romano A, Nzelu CO, Owens K, Sanders MJ, Dobson D, Cotton JA, Grigg ME, Beverley SM, Sacks D.

PLoS Genet. 2019 May 15;15(5):e1008042. doi: 10.1371/journal.pgen.1008042. eCollection 2019 May.


Population genomic and evolutionary modelling analyses reveal a single major QTL for ivermectin drug resistance in the pathogenic nematode, Haemonchus contortus.

Doyle SR, Illingworth CJR, Laing R, Bartley DJ, Redman E, Martinelli A, Holroyd N, Morrison AA, Rezansoff A, Tracey A, Devaney E, Berriman M, Sargison N, Cotton JA, Gilleard JS.

BMC Genomics. 2019 Mar 15;20(1):218. doi: 10.1186/s12864-019-5592-6.


Genome-wide Approaches to Investigate Anthelmintic Resistance.

Doyle SR, Cotton JA.

Trends Parasitol. 2019 Apr;35(4):289-301. doi: 10.1016/ Epub 2019 Feb 4. Review.


Population genetic analysis of Chadian Guinea worms reveals that human and non-human hosts share common parasite populations.

Thiele EA, Eberhard ML, Cotton JA, Durrant C, Berg J, Hamm K, Ruiz-Tiben E.

PLoS Negl Trop Dis. 2018 Oct 4;12(10):e0006747. doi: 10.1371/journal.pntd.0006747. eCollection 2018 Oct.


Eradication genomics-lessons for parasite control.

Cotton JA, Berriman M, Dalén L, Barnes I.

Science. 2018 Jul 13;361(6398):130-131. doi: 10.1126/science.aar6609. Epub 2018 Jul 12. No abstract available.


Leishmania naiffi and Leishmania guyanensis reference genomes highlight genome structure and gene evolution in the Viannia subgenus.

Coughlan S, Taylor AS, Feane E, Sanders M, Schonian G, Cotton JA, Downing T.

R Soc Open Sci. 2018 Apr 25;5(4):172212. doi: 10.1098/rsos.172212. eCollection 2018 Apr.


Integrated genomic and metabolomic profiling of ISC1, an emerging Leishmania donovani population in the Indian subcontinent.

Cuypers B, Berg M, Imamura H, Dumetz F, De Muylder G, Domagalska MA, Rijal S, Bhattarai NR, Maes I, Sanders M, Cotton JA, Meysman P, Laukens K, Dujardin JC.

Infect Genet Evol. 2018 Aug;62:170-178. doi: 10.1016/j.meegid.2018.04.021. Epub 2018 Apr 19.


Transcriptomic profiling of nematode parasites surviving vaccine exposure.

Sallé G, Laing R, Cotton JA, Maitland K, Martinelli A, Holroyd N, Tracey A, Berriman M, Smith WD, Newlands GFJ, Hanks E, Devaney E, Britton C.

Int J Parasitol. 2018 Apr;48(5):395-402. doi: 10.1016/j.ijpara.2018.01.004. Epub 2018 Mar 10.


Genetic Diversity of Cryptosporidium hominis in a Bangladeshi Community as Revealed by Whole-Genome Sequencing.

Gilchrist CA, Cotton JA, Burkey C, Arju T, Gilmartin A, Lin Y, Ahmed E, Steiner K, Alam M, Ahmed S, Robinson G, Zaman SU, Kabir M, Sanders M, Chalmers RM, Ahmed T, Ma JZ, Haque R, Faruque ASG, Berriman M, Petri WA.

J Infect Dis. 2018 Jun 20;218(2):259-264. doi: 10.1093/infdis/jiy121.


Complete avian malaria parasite genomes reveal features associated with lineage-specific evolution in birds and mammals.

Böhme U, Otto TD, Cotton JA, Steinbiss S, Sanders M, Oyola SO, Nicot A, Gandon S, Patra KP, Herd C, Bushell E, Modrzynska KK, Billker O, Vinetz JM, Rivero A, Newbold CI, Berriman M.

Genome Res. 2018 Apr;28(4):547-560. doi: 10.1101/gr.218123.116. Epub 2018 Mar 2.


Genome wide comparison of Ethiopian Leishmania donovani strains reveals differences potentially related to parasite survival.

Zackay A, Cotton JA, Sanders M, Hailu A, Nasereddin A, Warburg A, Jaffe CL.

PLoS Genet. 2018 Jan 9;14(1):e1007133. doi: 10.1371/journal.pgen.1007133. eCollection 2018 Jan.


A Genome Resequencing-Based Genetic Map Reveals the Recombination Landscape of an Outbred Parasitic Nematode in the Presence of Polyploidy and Polyandry.

Doyle SR, Laing R, Bartley DJ, Britton C, Chaudhry U, Gilleard JS, Holroyd N, Mable BK, Maitland K, Morrison AA, Tait A, Tracey A, Berriman M, Devaney E, Cotton JA, Sargison ND.

Genome Biol Evol. 2018 Feb 1;10(2):396-409. doi: 10.1093/gbe/evx269.


A method for single pair mating in an obligate parasitic nematode.

Sargison ND, Redman E, Morrison AA, Bartley DJ, Jackson F, Naghra-van Gijzel H, Holroyd N, Berriman M, Cotton JA, Gilleard JS.

Int J Parasitol. 2018 Feb;48(2):159-165. doi: 10.1016/j.ijpara.2017.08.010. Epub 2017 Oct 27.


Gene Expression in Leishmania Is Regulated Predominantly by Gene Dosage.

Iantorno SA, Durrant C, Khan A, Sanders MJ, Beverley SM, Warren WC, Berriman M, Sacks DL, Cotton JA, Grigg ME.

MBio. 2017 Sep 12;8(5). pii: e01393-17. doi: 10.1128/mBio.01393-17.


Giardia co-infection promotes the secretion of antimicrobial peptides beta-defensin 2 and trefoil factor 3 and attenuates attaching and effacing bacteria-induced intestinal disease.

Manko A, Motta JP, Cotton JA, Feener T, Oyeyemi A, Vallance BA, Wallace JL, Buret AG.

PLoS One. 2017 Jun 16;12(6):e0178647. doi: 10.1371/journal.pone.0178647. eCollection 2017.


Modulation of Aneuploidy in Leishmania donovani during Adaptation to Different In Vitro and In Vivo Environments and Its Impact on Gene Expression.

Dumetz F, Imamura H, Sanders M, Seblova V, Myskova J, Pescher P, Vanaerschot M, Meehan CJ, Cuypers B, De Muylder G, Späth GF, Bussotti G, Vermeesch JR, Berriman M, Cotton JA, Volf P, Dujardin JC, Domagalska MA.

MBio. 2017 May 23;8(3). pii: e00599-17. doi: 10.1128/mBio.00599-17.


The Expanding World of Human Leishmaniasis.

Cotton JA.

Trends Parasitol. 2017 May;33(5):341-344. doi: 10.1016/ Epub 2017 Mar 17.


The genome of Leishmania adleri from a mammalian host highlights chromosome fission in Sauroleishmania.

Coughlan S, Mulhair P, Sanders M, Schonian G, Cotton JA, Downing T.

Sci Rep. 2017 Mar 3;7:43747. doi: 10.1038/srep43747.


Plasmodium malariae and P. ovale genomes provide insights into malaria parasite evolution.

Rutledge GG, Böhme U, Sanders M, Reid AJ, Cotton JA, Maiga-Ascofare O, Djimdé AA, Apinjoh TO, Amenga-Etego L, Manske M, Barnwell JW, Renaud F, Ollomo B, Prugnolle F, Anstey NM, Auburn S, Price RN, McCarthy JS, Kwiatkowski DP, Newbold CI, Berriman M, Otto TD.

Nature. 2017 Feb 2;542(7639):101-104. doi: 10.1038/nature21038. Epub 2017 Jan 25.


Comparative genomics of canine-isolated Leishmania (Leishmania) amazonensis from an endemic focus of visceral leishmaniasis in Governador Valadares, southeastern Brazil.

Valdivia HO, Almeida LV, Roatt BM, Reis-Cunha JL, Pereira AA, Gontijo C, Fujiwara RT, Reis AB, Sanders MJ, Cotton JA, Bartholomeu DC.

Sci Rep. 2017 Jan 16;7:40804. doi: 10.1038/srep40804.


Stage-Specific Transcriptome and Proteome Analyses of the Filarial Parasite Onchocerca volvulus and Its Wolbachia Endosymbiont.

Bennuru S, Cotton JA, Ribeiro JM, Grote A, Harsha B, Holroyd N, Mhashilkar A, Molina DM, Randall AZ, Shandling AD, Unnasch TR, Ghedin E, Berriman M, Lustigman S, Nutman TB.

MBio. 2016 Nov 23;7(6). pii: e02028-16. doi: 10.1128/mBio.02028-16.


The genome of Onchocerca volvulus, agent of river blindness.

Cotton JA, Bennuru S, Grote A, Harsha B, Tracey A, Beech R, Doyle SR, Dunn M, Hotopp JC, Holroyd N, Kikuchi T, Lambert O, Mhashilkar A, Mutowo P, Nursimulu N, Ribeiro JM, Rogers MB, Stanley E, Swapna LS, Tsai IJ, Unnasch TR, Voronin D, Parkinson J, Nutman TB, Ghedin E, Berriman M, Lustigman S.

Nat Microbiol. 2016 Nov 21;2:16216. doi: 10.1038/nmicrobiol.2016.216.


Reduced Efficacy of Praziquantel Against Schistosoma mansoni Is Associated With Multiple Rounds of Mass Drug Administration.

Crellen T, Walker M, Lamberton PH, Kabatereine NB, Tukahebwa EM, Cotton JA, Webster JP.

Clin Infect Dis. 2016 Nov 1;63(9):1151-1159. Epub 2016 Jul 28.


The genome of the yellow potato cyst nematode, Globodera rostochiensis, reveals insights into the basis of parasitism and virulence.

Eves-van den Akker S, Laetsch DR, Thorpe P, Lilley CJ, Danchin EG, Da Rocha M, Rancurel C, Holroyd NE, Cotton JA, Szitenberg A, Grenier E, Montarry J, Mimee B, Duceppe MO, Boyes I, Marvin JM, Jones LM, Yusup HB, Lafond-Lapalme J, Esquibet M, Sabeh M, Rott M, Overmars H, Finkers-Tomczak A, Smant G, Koutsovoulos G, Blok V, Mantelin S, Cock PJ, Phillips W, Henrissat B, Urwin PE, Blaxter M, Jones JT.

Genome Biol. 2016 Jun 10;17(1):124. doi: 10.1186/s13059-016-0985-1.


Haemonchus contortus: Genome Structure, Organization and Comparative Genomics.

Laing R, Martinelli A, Tracey A, Holroyd N, Gilleard JS, Cotton JA.

Adv Parasitol. 2016;93:569-98. doi: 10.1016/bs.apar.2016.02.016. Epub 2016 Apr 11. Review.


Evolutionary genomics of epidemic visceral leishmaniasis in the Indian subcontinent.

Imamura H, Downing T, Van den Broeck F, Sanders MJ, Rijal S, Sundar S, Mannaert A, Vanaerschot M, Berg M, De Muylder G, Dumetz F, Cuypers B, Maes I, Domagalska M, Decuypere S, Rai K, Uranw S, Bhattarai NR, Khanal B, Prajapati VK, Sharma S, Stark O, Schönian G, De Koning HP, Settimo L, Vanhollebeke B, Roy S, Ostyn B, Boelaert M, Maes L, Berriman M, Dujardin JC, Cotton JA.

Elife. 2016 Mar 22;5. pii: e12613. doi: 10.7554/eLife.12613.


Whole genome resequencing of the human parasite Schistosoma mansoni reveals population history and effects of selection.

Crellen T, Allan F, David S, Durrant C, Huckvale T, Holroyd N, Emery AM, Rollinson D, Aanensen DM, Berriman M, Webster JP, Cotton JA.

Sci Rep. 2016 Feb 16;6:20954. doi: 10.1038/srep20954.


The genomic basis of parasitism in the Strongyloides clade of nematodes.

Hunt VL, Tsai IJ, Coghlan A, Reid AJ, Holroyd N, Foth BJ, Tracey A, Cotton JA, Stanley EJ, Beasley H, Bennett HM, Brooks K, Harsha B, Kajitani R, Kulkarni A, Harbecke D, Nagayasu E, Nichol S, Ogura Y, Quail MA, Randle N, Xia D, Brattig NW, Soblik H, Ribeiro DM, Sanchez-Flores A, Hayashi T, Itoh T, Denver DR, Grant W, Stoltzfus JD, Lok JB, Murayama H, Wastling J, Streit A, Kikuchi T, Viney M, Berriman M.

Nat Genet. 2016 Mar;48(3):299-307. doi: 10.1038/ng.3495. Epub 2016 Feb 1.


In vitro selection of miltefosine resistance in promastigotes of Leishmania donovani from Nepal: genomic and metabolomic characterization.

Shaw CD, Lonchamp J, Downing T, Imamura H, Freeman TM, Cotton JA, Sanders M, Blackburn G, Dujardin JC, Rijal S, Khanal B, Illingworth CJ, Coombs GH, Carter KC.

Mol Microbiol. 2016 Mar;99(6):1134-48. doi: 10.1111/mmi.13291. Epub 2016 Feb 9.


Disruptions of Host Immunity and Inflammation by Giardia Duodenalis: Potential Consequences for Co-Infections in the Gastro-Intestinal Tract.

Cotton JA, Amat CB, Buret AG.

Pathogens. 2015 Nov 10;4(4):764-92. doi: 10.3390/pathogens4040764. Review.


Speciation processes in putative island endemic sister bat species: false impressions from mitochondrial DNA and microsatellite data.

Kuo HC, Chen SF, Fang YP, Cotton JA, Parker JD, Csorba G, Lim BK, Eger JL, Chen CH, Chou CH, Rossiter SJ.

Mol Ecol. 2015 Dec;24(23):5910-26. doi: 10.1111/mec.13425. Epub 2015 Nov 20.


Giardia duodenalis Surface Cysteine Proteases Induce Cleavage of the Intestinal Epithelial Cytoskeletal Protein Villin via Myosin Light Chain Kinase.

Bhargava A, Cotton JA, Dixon BR, Gedamu L, Yates RM, Buret AG.

PLoS One. 2015 Sep 3;10(9):e0136102. doi: 10.1371/journal.pone.0136102. eCollection 2015.


Modelling the effects of mass drug administration on the molecular epidemiology of schistosomes.

Lamberton PH, Crellen T, Cotton JA, Webster JP.

Adv Parasitol. 2015 Mar;87:293-327. doi: 10.1016/bs.apar.2014.12.006. Epub 2015 Feb 7.


Mosaic aneuploidy in Leishmania: the perspective of whole genome sequencing.

Dujardin JC, Mannaert A, Durrant C, Cotton JA.

Trends Parasitol. 2014 Dec;30(12):554-5. doi: 10.1016/ Epub 2014 Oct 22. No abstract available.


Giardia duodenalis infection reduces granulocyte infiltration in an in vivo model of bacterial toxin-induced colitis and attenuates inflammation in human intestinal tissue.

Cotton JA, Motta JP, Schenck LP, Hirota SA, Beck PL, Buret AG.

PLoS One. 2014 Oct 7;9(10):e109087. doi: 10.1371/journal.pone.0109087. eCollection 2014.


Whipworm genome and dual-species transcriptome analyses provide molecular insights into an intimate host-parasite interaction.

Foth BJ, Tsai IJ, Reid AJ, Bancroft AJ, Nichol S, Tracey A, Holroyd N, Cotton JA, Stanley EJ, Zarowiecki M, Liu JZ, Huckvale T, Cooper PJ, Grencis RK, Berriman M.

Nat Genet. 2014 Jul;46(7):693-700. doi: 10.1038/ng.3010. Epub 2014 Jun 15.


Giardia duodenalis cathepsin B proteases degrade intestinal epithelial interleukin-8 and attenuate interleukin-8-induced neutrophil chemotaxis.

Cotton JA, Bhargava A, Ferraz JG, Yates RM, Beck PL, Buret AG.

Infect Immun. 2014 Jul;82(7):2772-87. doi: 10.1128/IAI.01771-14. Epub 2014 Apr 14.


The genome and life-stage specific transcriptomes of Globodera pallida elucidate key aspects of plant parasitism by a cyst nematode.

Cotton JA, Lilley CJ, Jones LM, Kikuchi T, Reid AJ, Thorpe P, Tsai IJ, Beasley H, Blok V, Cock PJ, Eves-van den Akker S, Holroyd N, Hunt M, Mantelin S, Naghra H, Pain A, Palomares-Rius JE, Zarowiecki M, Berriman M, Jones JT, Urwin PE.

Genome Biol. 2014 Mar 3;15(3):R43. doi: 10.1186/gb-2014-15-3-r43.


Genomic confirmation of hybridisation and recent inbreeding in a vector-isolated Leishmania population.

Rogers MB, Downing T, Smith BA, Imamura H, Sanders M, Svobodova M, Volf P, Berriman M, Cotton JA, Smith DF.

PLoS Genet. 2014 Jan;10(1):e1004092. doi: 10.1371/journal.pgen.1004092. Epub 2014 Jan 16.


The peculiar epidemiology of dracunculiasis in Chad.

Eberhard ML, Ruiz-Tiben E, Hopkins DR, Farrell C, Toe F, Weiss A, Withers PC, Jenks MH, Thiele EA, Cotton JA, Hance Z, Holroyd N, Cama VA, Tahir MA, Mounda T.

Am J Trop Med Hyg. 2014 Jan;90(1):61-70. doi: 10.4269/ajtmh.13-0554. Epub 2013 Nov 25.


Phylogenomic analyses elucidate the evolutionary relationships of bats.

Tsagkogeorga G, Parker J, Stupka E, Cotton JA, Rossiter SJ.

Curr Biol. 2013 Nov 18;23(22):2262-2267. doi: 10.1016/j.cub.2013.09.014. Epub 2013 Oct 31.


Genome-wide signatures of convergent evolution in echolocating mammals.

Parker J, Tsagkogeorga G, Cotton JA, Liu Y, Provero P, Stupka E, Rossiter SJ.

Nature. 2013 Oct 10;502(7470):228-31. doi: 10.1038/nature12511. Epub 2013 Sep 4.


The genome and transcriptome of Haemonchus contortus, a key model parasite for drug and vaccine discovery.

Laing R, Kikuchi T, Martinelli A, Tsai IJ, Beech RN, Redman E, Holroyd N, Bartley DJ, Beasley H, Britton C, Curran D, Devaney E, Gilabert A, Hunt M, Jackson F, Johnston SL, Kryukov I, Li K, Morrison AA, Reid AJ, Sargison N, Saunders GI, Wasmuth JD, Wolstenholme A, Berriman M, Gilleard JS, Cotton JA.

Genome Biol. 2013 Aug 28;14(8):R88. doi: 10.1186/gb-2013-14-8-r88.


The evolution of bat vestibular systems in the face of potential antagonistic selection pressures for flight and echolocation.

Davies KT, Bates PJ, Maryanto I, Cotton JA, Rossiter SJ.

PLoS One. 2013 Apr 24;8(4):e61998. doi: 10.1371/journal.pone.0061998. Print 2013.

Supplemental Content

Loading ...
Support Center