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Items: 1 to 50 of 88

1.

Sustained efficacy and seroconversion with the Toll-like receptor 7 agonist GS-9620 in the Woodchuck model of chronic hepatitis B.

Menne S, Tumas DB, Liu KH, Thampi L, AlDeghaither D, Baldwin BH, Bellezza CA, Cote PJ, Zheng J, Halcomb R, Fosdick A, Fletcher SP, Daffis S, Li L, Yue P, Wolfgang GH, Tennant BC.

J Hepatol. 2015 Jun;62(6):1237-45. doi: 10.1016/j.jhep.2014.12.026. Epub 2015 Jan 2.

2.

Identification of an intrahepatic transcriptional signature associated with self-limiting infection in the woodchuck model of hepatitis B.

Fletcher SP, Chin DJ, Cheng DT, Ravindran P, Bitter H, Gruenbaum L, Cote PJ, Ma H, Klumpp K, Menne S.

Hepatology. 2013 Jan;57(1):13-22. doi: 10.1002/hep.25954.

3.

Electroporation enhances immunogenicity of a DNA vaccine expressing woodchuck hepatitis virus surface antigen in woodchucks.

Liu KH, Ascenzi MA, Bellezza CA, Bezuidenhout AJ, Cote PJ, Gonzalez-Aseguinolaza G, Hannaman D, Luxembourg A, Evans CF, Tennant BC, Menne S.

J Virol. 2011 May;85(10):4853-62. doi: 10.1128/JVI.02437-10. Epub 2011 Mar 9.

4.

Glucosidase inhibition enhances presentation of de-N-glycosylated hepatitis B virus epitopes by major histocompatibility complex class I in vitro and in woodchucks.

Norton PA, Menne S, Sinnathamby G, Betesh L, Cote PJ, Philip R, Mehta AS, Tennant BC, Block TM.

Hepatology. 2010 Oct;52(4):1242-50. doi: 10.1002/hep.23806.

5.

Rapid immunity to vaccination with woodchuck hepatitis virus surface antigen using cationic liposome-DNA complexes as adjuvant.

Cote PJ, Butler SD, George AL, Fairman J, Gerin JL, Tennant BC, Menne S.

J Med Virol. 2009 Oct;81(10):1760-72. doi: 10.1002/jmv.21566.

PMID:
19697409
6.

Calculating the return on investment of mobile healthcare.

Oriol NE, Cote PJ, Vavasis AP, Bennet J, Delorenzo D, Blanc P, Kohane I.

BMC Med. 2009 Jun 2;7:27. doi: 10.1186/1741-7015-7-27.

7.

Antiviral effects of lamivudine, emtricitabine, adefovir dipivoxil, and tenofovir disoproxil fumarate administered orally alone and in combination to woodchucks with chronic woodchuck hepatitis virus infection.

Menne S, Butler SD, George AL, Tochkov IA, Zhu Y, Xiong S, Gerin JL, Cote PJ, Tennant BC.

Antimicrob Agents Chemother. 2008 Oct;52(10):3617-32. doi: 10.1128/AAC.00654-08. Epub 2008 Aug 1.

8.

Serologic survey of woodchuck hepatitis virus in North Carolina woodchucks (Marmota monax).

Cullen JM, Lindsey-Pegram D, Cote PJ.

J Zoo Wildl Med. 2008 Jun;39(2):263-5.

PMID:
18634221
9.

Immunogenicity in mice and rabbits of DNA vaccines expressing woodchuck hepatitis virus antigens.

Luxembourg A, Hannaman D, Wills K, Bernard R, Tennant BC, Menne S, Cote PJ.

Vaccine. 2008 Jul 29;26(32):4025-33. doi: 10.1016/j.vaccine.2008.05.021. Epub 2008 Jun 2.

PMID:
18556096
11.

Antiviral effect of orally administered (-)-beta-D-2-aminopurine dioxolane in woodchucks with chronic woodchuck hepatitis virus infection.

Menne S, Asif G, Narayanasamy J, Butler SD, George AL, Hurwitz SJ, Schinazi RF, Chu CK, Cote PJ, Gerin JL, Tennant BC.

Antimicrob Agents Chemother. 2007 Sep;51(9):3177-84. Epub 2007 Jul 2.

12.

Immunosuppression reactivates viral replication long after resolution of woodchuck hepatitis virus infection.

Menne S, Cote PJ, Butler SD, Toshkov IA, Gerin JL, Tennant BC.

Hepatology. 2007 Mar;45(3):614-22.

PMID:
17326155
13.
14.

Clevudine inhibits hepatitis delta virus viremia: a pilot study of chronically infected woodchucks.

Casey J, Cote PJ, Toshkov IA, Chu CK, Gerin JL, Hornbuckle WE, Tennant BC, Korba BE.

Antimicrob Agents Chemother. 2005 Oct;49(10):4396-9.

15.

Antiviral effect of oral administration of tenofovir disoproxil fumarate in woodchucks with chronic woodchuck hepatitis virus infection.

Menne S, Cote PJ, Korba BE, Butler SD, George AL, Tochkov IA, Delaney WE 4th, Xiong S, Gerin JL, Tennant BC.

Antimicrob Agents Chemother. 2005 Jul;49(7):2720-8.

16.

Clevudine therapy with vaccine inhibits progression of chronic hepatitis and delays onset of hepatocellular carcinoma in chronic woodchuck hepatitis virus infection.

Korba BE, Cote PJ, Menne S, Toshkov I, Baldwin BH, Wells FV, Tennant BC, Gerin JL.

Antivir Ther. 2004 Dec;9(6):937-52.

PMID:
15651753
17.

Hepatocellular carcinoma in the woodchuck model of hepatitis B virus infection.

Tennant BC, Toshkov IA, Peek SF, Jacob JR, Menne S, Hornbuckle WE, Schinazi RD, Korba BE, Cote PJ, Gerin JL.

Gastroenterology. 2004 Nov;127(5 Suppl 1):S283-93. Review.

PMID:
15508096
18.

Interferon-gamma-associated responses to woodchuck hepatitis virus infection in neonatal woodchucks and virus-infected hepatocytes.

Wang Y, Jacob JR, Menne S, Bellezza CA, Tennant BC, Gerin JL, Cote PJ.

J Viral Hepat. 2004 Sep;11(5):404-17.

PMID:
15357645
19.

Suppression of lamivudine-resistant B-domain mutants by adefovir dipivoxil in the woodchuck hepatitis virus model.

Jacob JR, Korba BE, Cote PJ, Toshkov I, Delaney WE 4th, Gerin JL, Tennant BC.

Antiviral Res. 2004 Aug;63(2):115-21.

PMID:
15302140
20.

Integration of woodchuck hepatitis and N-myc rearrangement determine size and histologic grade of hepatic tumors.

Jacob JR, Sterczer A, Toshkov IA, Yeager AE, Korba BE, Cote PJ, Buendia MA, Gerin JL, Tennant BC.

Hepatology. 2004 Apr;39(4):1008-16.

PMID:
15057905
21.

Measurement of cell-mediated immune response in woodchucks.

Menne S, Cote PJ.

Methods Mol Med. 2004;96:27-36. No abstract available.

PMID:
14762256
22.

Kinetics of viremia and acute liver injury in relation to outcome of neonatal woodchuck hepatitis virus infection.

Wang Y, Menne S, Baldwin BH, Tennant BC, Gerin JL, Cote PJ.

J Med Virol. 2004 Mar;72(3):406-15.

PMID:
14748064
23.

Role of type 1 versus type 2 immune responses in liver during the onset of chronic woodchuck hepatitis virus infection.

Wang Y, Menne S, Jacob JR, Tennant BC, Gerin JL, Cote PJ.

Hepatology. 2003 Apr;37(4):771-80.

PMID:
12668969
25.

Real-time polymerase chain reaction assays for leukocyte CD and cytokine mRNAs of the Eastern woodchuck (Marmota monax).

Menne S, Wang Y, Butler SD, Gerin JL, Cote PJ, Tennant BC.

Vet Immunol Immunopathol. 2002 Aug;87(1-2):97-105.

PMID:
12052347
29.

Antiviral activity of clevudine [L-FMAU, (1-(2-fluoro-5-methyl-beta, L-arabinofuranosyl) uracil)] against woodchuck hepatitis virus replication and gene expression in chronically infected woodchucks (Marmota monax).

Peek SF, Cote PJ, Jacob JR, Toshkov IA, Hornbuckle WE, Baldwin BH, Wells FV, Chu CK, Gerin JL, Tennant BC, Korba BE.

Hepatology. 2001 Jan;33(1):254-66.

PMID:
11124844
30.

Temporal pathogenesis of experimental neonatal woodchuck hepatitis virus infection: increased initial viral load and decreased severity of acute hepatitis during the development of chronic viral infection.

Cote PJ, Toshkov I, Bellezza C, Ascenzi M, Roneker C, Ann Graham L, Baldwin BH, Gaye K, Nakamura I, Korba BE, Tennant BC, Gerin JL.

Hepatology. 2000 Oct;32(4 Pt 1):807-17.

PMID:
11003627
31.

Antiviral activities of oral 1-O-hexadecylpropanediol-3-phosphoacyclovir and acyclovir in woodchucks with chronic woodchuck hepatitis virus infection.

Hostetler KY, Beadle JR, Hornbuckle WE, Bellezza CA, Tochkov IA, Cote PJ, Gerin JL, Korba BE, Tennant BC.

Antimicrob Agents Chemother. 2000 Jul;44(7):1964-9.

32.

Preclinical investigation of L-FMAU as an anti-hepatitis B virus agent.

Chu CK, Boudinot FD, Peek SF, Hong JH, Choi Y, Korba BE, Gerin JL, Cote PJ, Tennant BC, Cheng YC.

Antivir Ther. 1998;3(Suppl 3):113-21. Review.

PMID:
10726061
33.

Effects of age and viral determinants on chronicity as an outcome of experimental woodchuck hepatitis virus infection.

Cote PJ, Korba BE, Miller RH, Jacob JR, Baldwin BH, Hornbuckle WE, Purcell RH, Tennant BC, Gerin JL.

Hepatology. 2000 Jan;31(1):190-200.

PMID:
10613745
34.

Licensed recombinant hepatitis B vaccines protect chimpanzees against infection with the prototype surface gene mutant of hepatitis B virus.

Ogata N, Cote PJ, Zanetti AR, Miller RH, Shapiro M, Gerin J, Purcell RH.

Hepatology. 1999 Sep;30(3):779-86.

PMID:
10462386
35.

Antiviral activity and toxicity of fialuridine in the woodchuck model of hepatitis B virus infection.

Tennant BC, Baldwin BH, Graham LA, Ascenzi MA, Hornbuckle WE, Rowland PH, Tochkov IA, Yeager AE, Erb HN, Colacino JM, Lopez C, Engelhardt JA, Bowsher RR, Richardson FC, Lewis W, Cote PJ, Korba BE, Gerin JL.

Hepatology. 1998 Jul;28(1):179-91.

PMID:
9657111
36.

Hepatitis D viremia following orthotopic liver transplantation involves a typical HDV virion with a hepatitis B surface antigen envelope.

Smedile A, Casey JL, Cote PJ, Durazzo M, Lavezzo B, Purcell RH, Rizzetto M, Gerin JL.

Hepatology. 1998 Jun;27(6):1723-9.

PMID:
9620349
37.

Titration of recombinant woodchuck hepatitis virus DNA in adult woodchucks.

Chen HS, Miller RH, Hornbuckle WE, Tennant BC, Cote PJ, Gerin JL, Purcell RH.

J Med Virol. 1998 Feb;54(2):92-4.

PMID:
9496365
38.

Hepatic expression of the woodchuck hepatitis virus X-antigen during acute and chronic infection and detection of a woodchuck hepatitis virus X-antigen antibody response.

Jacob JR, Ascenzi MA, Roneker CA, Toshkov IA, Cote PJ, Gerin JL, Tennant BC.

Hepatology. 1997 Dec;26(6):1607-15.

PMID:
9398005
39.

Cloning and characterization of partial cDNAs for woodchuck cytokines and CD3epsilon with applications for the detection of RNA expression in tissues by RT-PCR assay.

Nakamura I, Nupp JT, Rao BS, Buckler-White A, Engle RE, Casey JL, Gerin JL, Cote PJ.

J Med Virol. 1997 Sep;53(1):85-95.

PMID:
9298738
40.
42.

Woodchuck hepatitis virus surface antigen induces nitric oxide synthesis in hepatocytes: possible role in hepatocarcinogenesis.

Liu RH, Jacob JR, Hotchkiss JH, Cote PJ, Gerin JL, Tennant BC.

Carcinogenesis. 1994 Dec;15(12):2875-7.

PMID:
8001249
43.

DNA ploidy analysis of hepatic preneoplastic and neoplastic lesions in woodchucks experimentally infected with woodchuck hepatitis virus.

Mi LJ, Patil J, Hornbuckle WE, Cote PJ, Gerin JL, Tennant BC, Paronetto F.

Hepatology. 1994 Jul;20(1 Pt 1):21-9.

PMID:
8020890
44.

The woodchuck hepatitis virus X gene is important for establishment of virus infection in woodchucks.

Chen HS, Kaneko S, Girones R, Anderson RW, Hornbuckle WE, Tennant BC, Cote PJ, Gerin JL, Purcell RH, Miller RH.

J Virol. 1993 Mar;67(3):1218-26.

45.

Antibodies to polymerized albumin in woodchuck hepatitis virus infection.

Lee WM, Iverson A, McLeod L, Walpole HE, Arnaud P, Cote PJ, Gerin JL, Tennant BC.

Viral Immunol. 1993 Spring;6(1):13-9.

PMID:
8476506
46.

New enzyme immunoassays for the serologic detection of woodchuck hepatitis virus infection.

Cote PJ, Roneker C, Cass K, Schödel F, Peterson D, Tennant B, De Noronha F, Gerin J.

Viral Immunol. 1993 Summer;6(2):161-9.

PMID:
8216715
47.

Power laws, flicker noise, and the Barkhausen effect.

Meisel LV, Cote PJ.

Phys Rev B Condens Matter. 1992 Nov 1;46(17):10822-10828. No abstract available.

PMID:
10002942
48.

Hyperbolic distributions and fractal character of fracture surfaces.

McAnulty P, Meisel LV, Cote PJ.

Phys Rev A. 1992 Sep 15;46(6):3523-3526. No abstract available.

PMID:
9908520
49.

The precore gene of the woodchuck hepatitis virus genome is not essential for viral replication in the natural host.

Chen HS, Kew MC, Hornbuckle WE, Tennant BC, Cote PJ, Gerin JL, Purcell RH, Miller RH.

J Virol. 1992 Sep;66(9):5682-4.

50.

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