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Genomic Analyses of PMBL Reveal New Drivers and Mechanisms of Sensitivity to PD-1 Blockade.

Chapuy B, Stewart C, Dunford AJ, Kim J, Wienand K, Kamburov A, Griffin GK, Chen PH, Lako A, Redd R, Cote CM, Ducar MD, Thorner AR, Rodig SJ, Getz G, Shipp MA.

Blood. 2019 Oct 28. pii: blood.2019002067. doi: 10.1182/blood.2019002067. [Epub ahead of print]


The Single-Clinician-Operator/Anesthetist Model for Dental Deep Sedation/Anesthesia: A Major Safety Issue for Children.

Coté CJ, Brown RE Jr, Kaplan A.

JAMA Pediatr. 2019 Oct 28. doi: 10.1001/jamapediatrics.2019.3823. [Epub ahead of print] No abstract available.


Elemental: An Open-Source Wireless Hardware and Software Platform for Building Energy and Indoor Environmental Monitoring and Control.

Ali AS, Coté C, Heidarinejad M, Stephens B.

Sensors (Basel). 2019 Sep 18;19(18). pii: E4017. doi: 10.3390/s19184017.


Patient-reported disease burden in oculopharyngeal muscular dystrophy.

Kurtz NS, Cote C, Heatwole C, Gagnon C, Youssof S.

Muscle Nerve. 2019 Dec;60(6):724-731. doi: 10.1002/mus.26712. Epub 2019 Oct 30.


Long-Term Effects of a Multimodal Physiotherapy Program on the Severity of Somatosensory Tinnitus and Identification of Clinical Indicators Predicting Favorable Outcomes of the Program.

Côté C, Baril I, Morency CÈ, Montminy S, Couture M, Leblond J, Roos M, Roy JS.

J Am Acad Audiol. 2019 Sep;30(8):720-730. doi: 10.3766/jaaa.17147.


A Francisella novicida Mutant, Lacking the Soluble Lytic Transglycosylase Slt, Exhibits Defects in Both Growth and Virulence.

Bachert BA, Biryukov SS, Chua J, Rodriguez SA, Toothman RG Jr, Cote CK, Klimko CP, Hunter M, Shoe JL, Williams JA, Kuehl KA, Biot FV, Bozue JA.

Front Microbiol. 2019 Jun 14;10:1343. doi: 10.3389/fmicb.2019.01343. eCollection 2019.


Guidelines for Monitoring and Management of Pediatric Patients Before, During, and After Sedation for Diagnostic and Therapeutic Procedures.


Pediatrics. 2019 Jun;143(6). pii: e20191000. doi: 10.1542/peds.2019-1000.


Deteriorated Cardiometabolic Risk Profile in Individuals With Excessive Blood Pressure Response to Submaximal Exercise.

Côté CE, Rhéaume C, Poirier P, Després JP, Alméras N.

Am J Hypertens. 2019 Sep 24;32(10):945-952. doi: 10.1093/ajh/hpz087.


Quebec Serve and Protect Low Back Pain Study: What About Mental Quality of Life?

Benyamina Douma N, Côté C, Lacasse A.

Saf Health Work. 2019 Mar;10(1):39-46. doi: 10.1016/ Epub 2018 Sep 6.


Correction: Two stable variants of Burkholderia pseudomallei strain MSHR5848 express broadly divergent in vitro phenotypes associated with their virulence differences.

Shea AA, Bernhards RC, Cote CK, Chase CJ, Koehler JW, Klimko CP, Ladner JT, Rozak DA, Wolcott MJ, Fetterer DP, Kern SJ, Koroleva GI, Lovett SP, Palacios GF, Toothman RG, Bozue JA, Worsham PL, Welkos SL.

PLoS One. 2019 Apr 4;14(4):e0215200. doi: 10.1371/journal.pone.0215200. eCollection 2019.


The Society for Pediatric Anesthesia recommendations for the use of opioids in children during the perioperative period.

Cravero JP, Agarwal R, Berde C, Birmingham P, Coté CJ, Galinkin J, Isaac L, Kost-Byerly S, Krodel D, Maxwell L, Voepel-Lewis T, Sethna N, Wilder R.

Paediatr Anaesth. 2019 Jun;29(6):547-571. doi: 10.1111/pan.13639. Epub 2019 Jun 11.


Soy Isoflavone Supplementation Increases Long Interspersed Nucleotide Element-1 (LINE-1) Methylation in Head and Neck Squamous Cell Carcinoma.

Rozek LS, Virani S, Bellile EL, Taylor JMG, Sartor MA, Zarins KR, Virani A, Cote C, Worden FP, Mark MEP, McLean SA, Duffy SA, Yoo GH, Saba NF, Shin DM, Kucuk O, Wolf GT.

Nutr Cancer. 2019;71(5):772-780. doi: 10.1080/01635581.2019.1577981. Epub 2019 Mar 12.


CRISPR/CAS9 targeted CAPTURE of mammalian genomic regions for characterization by NGS.

Slesarev A, Viswanathan L, Tang Y, Borgschulte T, Achtien K, Razafsky D, Onions D, Chang A, Cote C.

Sci Rep. 2019 Mar 5;9(1):3587. doi: 10.1038/s41598-019-39667-4.


Formaldehyde and Glutaraldehyde Inactivation of Bacterial Tier 1 Select Agents in Tissues.

Chua J, Bozue JA, Klimko CP, Shoe JL, Ruiz SI, Jensen CL, Tobery SA, Crumpler JM, Chabot DJ, Quirk AV, Hunter M, Harbourt DE, Friedlander AM, Cote CK.

Emerg Infect Dis. 2019 May;25(5):919-926. doi: 10.3201/eid2505.180928. Epub 2019 May 17.


Chronic opioid use after coronary bypass surgery.

Hirji SA, Landino S, Cote C, Lee J, Orhurhu V, Shah RM, McGurk S, Kaneko T, Shekar P, Pelletier MP.

J Card Surg. 2019 Feb;34(2):67-73. doi: 10.1111/jocs.13981. Epub 2019 Jan 9.


Production of recycled manure solids for bedding in Canadian dairy farms: I. Solid-liquid separation.

Fournel S, Godbout S, Ruel P, Fortin A, Généreux M, Côté C, Landry C, Pellerin D.

J Dairy Sci. 2019 Feb;102(2):1832-1846. doi: 10.3168/jds.2018-14966. Epub 2018 Dec 20.


Production of recycled manure solids for use as bedding in Canadian dairy farms: II. Composting methods.

Fournel S, Godbout S, Ruel P, Fortin A, Duquette-Lozeau K, Létourneau V, Généreux M, Lemieux J, Potvin D, Côté C, Duchaine C, Pellerin D.

J Dairy Sci. 2019 Feb;102(2):1847-1865. doi: 10.3168/jds.2018-14967. Epub 2018 Dec 20.


The requirement for a disease-specific patient-reported outcome measure of dysphagia in oculopharyngeal muscular dystrophy.

Côté C, Gagnon C, Youssof S, sKurtz N, Brais B.

Muscle Nerve. 2019 Apr;59(4):445-450. doi: 10.1002/mus.26405. Epub 2019 Jan 11.


Tumor-specific MHC-II expression drives a unique pattern of resistance to immunotherapy via LAG-3/FCRL6 engagement.

Johnson DB, Nixon MJ, Wang Y, Wang DY, Castellanos E, Estrada MV, Ericsson-Gonzalez PI, Cote CH, Salgado R, Sanchez V, Dean PT, Opalenik SR, Schreeder DM, Rimm DL, Kim JY, Bordeaux J, Loi S, Horn L, Sanders ME, Ferrell PB Jr, Xu Y, Sosman JA, Davis RS, Balko JM.

JCI Insight. 2018 Dec 20;3(24). pii: 120360. doi: 10.1172/jci.insight.120360.


Noncoding regions are the main source of targetable tumor-specific antigens.

Laumont CM, Vincent K, Hesnard L, Audemard É, Bonneil É, Laverdure JP, Gendron P, Courcelles M, Hardy MP, Côté C, Durette C, St-Pierre C, Benhammadi M, Lanoix J, Vobecky S, Haddad E, Lemieux S, Thibault P, Perreault C.

Sci Transl Med. 2018 Dec 5;10(470). pii: eaau5516. doi: 10.1126/scitranslmed.aau5516.


Disease progression in mice exposed to low-doses of aerosolized clinical isolates of Burkholderia pseudomallei.

Trevino SR, Klimko CP, Reed MC, Aponte-Cuadrado MJ, Hunter M, Shoe JL, Meyer JR, Dankmeyer JL, Biryukov SS, Quirk AV, Fritts KA, Kern SJ, Fetterer DP, Kohler LJ, Toothman RG, Bozue JA, Schellhase CW, Kreiselmeier N, Daye SP, Welkos SL, Soffler C, Worsham PL, Waag DM, Amemiya K, Cote CK.

PLoS One. 2018 Nov 30;13(11):e0208277. doi: 10.1371/journal.pone.0208277. eCollection 2018.


Nonredundant Roles of IL-21 and IL-4 in the Phased Initiation of Germinal Center B Cells and Subsequent Self-Renewal Transitions.

Gonzalez DG, Cote CM, Patel JR, Smith CB, Zhang Y, Nickerson KM, Zhang T, Kerfoot SM, Haberman AM.

J Immunol. 2018 Dec 15;201(12):3569-3579. doi: 10.4049/jimmunol.1500497. Epub 2018 Nov 16.


Use of antibiotics in broiler production: Global impacts and alternatives.

Mehdi Y, Létourneau-Montminy MP, Gaucher ML, Chorfi Y, Suresh G, Rouissi T, Brar SK, Côté C, Ramirez AA, Godbout S.

Anim Nutr. 2018 Jun;4(2):170-178. doi: 10.1016/j.aninu.2018.03.002. Epub 2018 Apr 3. Review.


Clinical pharmacology of oncology agents in older adults: A comprehensive review of how chronologic and functional age can influence treatment-related effects.

Nightingale G, Schwartz R, Kachur E, Dixon BN, Cote C, Barlow A, Barlow B, Medina P.

J Geriatr Oncol. 2019 Jan;10(1):4-30. doi: 10.1016/j.jgo.2018.06.008. Epub 2018 Jul 13. Review.


A Standard Method To Inactivate Bacillus anthracis Spores to Sterility via Gamma Irradiation.

Cote CK, Buhr T, Bernhards CB, Bohmke MD, Calm AM, Esteban-Trexler JS, Hunter M, Katoski SE, Kennihan N, Klimko CP, Miller JA, Minter ZA, Pfarr JW, Prugh AM, Quirk AV, Rivers BA, Shea AA, Shoe JL, Sickler TM, Young AA, Fetterer DP, Welkos SL, Bozue JA, McPherson D, Fountain AW 3rd, Gibbons HS.

Appl Environ Microbiol. 2018 May 31;84(12). pii: e00106-18. doi: 10.1128/AEM.00106-18. Print 2018 Jun 15.


Occupational and Ergonomic Factors Associated With Low Back Pain Among Car-patrol Police Officers: Findings From the Quebec Serve and Protect Low Back Pain Study.

Benyamina Douma N, Côté C, Lacasse A.

Clin J Pain. 2018 Oct;34(10):960-966. doi: 10.1097/AJP.0000000000000617.


Avirulent Bacillus anthracis Strain with Molecular Assay Targets as Surrogate for Irradiation-Inactivated Virulent Spores.

Plaut RD, Staab AB, Munson MA, Gebhardt JS, Klimko CP, Quirk AV, Cote CK, Buhr TL, Rossmaier RD, Bernhards RC, Love CE, Berk KL, Abshire TG, Rozak DA, Beck LC, Stibitz S, Goodwin BG, Smith MA, Sozhamannan S.

Emerg Infect Dis. 2018 Apr;24(4). doi: 10.3201/eid2404.171646.


Comparison of the MHC I Immunopeptidome Repertoire of B-Cell Lymphoblasts Using Two Isolation Methods.

Lanoix J, Durette C, Courcelles M, Cossette É, Comtois-Marotte S, Hardy MP, Côté C, Perreault C, Thibault P.

Proteomics. 2018 Jun;18(12):e1700251. doi: 10.1002/pmic.201700251. Epub 2018 Apr 24.


Concerns Regarding the Single Operator Model of Sedation in Young Children.

Agarwal R, Kaplan A, Brown R, Coté CJ.

Pediatrics. 2018 Apr;141(4). pii: e20172344. doi: 10.1542/peds.2017-2344. Epub 2018 Mar 2. No abstract available.


The anatomy of the pediatric airway: Has our knowledge changed in 120 years? A review of historic and recent investigations of the anatomy of the pediatric larynx.

Holzki J, Brown KA, Carroll RG, Coté CJ.

Paediatr Anaesth. 2018 Jan;28(1):13-22. doi: 10.1111/pan.13281. Epub 2017 Nov 17. Review.


Incorporating germination-induction into decontamination strategies for bacterial spores.

Kohler LJ, Quirk AV, Welkos SL, Cote CK.

J Appl Microbiol. 2018 Jan;124(1):2-14. doi: 10.1111/jam.13600. Epub 2017 Nov 5. Review.


Dimercaptosuccinic acid scintigraphy vs. ultrasound for renal parenchymal defects in children.

Marceau-Grimard M, Marion A, Côté C, Bolduc S, Dumont M, Moore K.

Can Urol Assoc J. 2017 Aug;11(8):260-264. doi: 10.5489/cuaj.4257.


Irrigation Water Sources and Time Intervals as Variables on the Presence of Campylobacter spp. and Listeria monocytogenes on Romaine Lettuce Grown in Muck Soil.

Guévremont E, Lamoureux L, Généreux M, Côté C.

J Food Prot. 2017 Jul;80(7):1182-1187. doi: 10.4315/0362-028X.JFP-16-551.


Germinal center B cell development has distinctly regulated stages completed by disengagement from T cell help.

Zhang TT, Gonzalez DG, Cote CM, Kerfoot SM, Deng S, Cheng Y, Magari M, Haberman AM.

Elife. 2017 May 12;6. pii: e19552. doi: 10.7554/eLife.19552.


Response to the Letter to the Editor.

Wilson S, Coté CJ.

Pediatr Dent. 2017 Mar 15;39(2):95-96. No abstract available.


A spontaneous mutation in kdsD, a biosynthesis gene for 3 Deoxy-D-manno-Octulosonic Acid, occurred in a ciprofloxacin resistant strain of Francisella tularensis and caused a high level of attenuation in murine models of tularemia.

Chance T, Chua J, Toothman RG, Ladner JT, Nuss JE, Raymond JL, Biot FV, Demons S, Miller L, Halasohoris S, Mou S, Koroleva G, Lovett S, Palacios G, Vietri NJ, Worsham PL, Cote CK, Kijek TM, Bozue JA.

PLoS One. 2017 Mar 22;12(3):e0174106. doi: 10.1371/journal.pone.0174106. eCollection 2017.


Quebec Serve and Protect Low Back Pain Study: A Web-based Cross-sectional Investigation of Prevalence and Functional Impact Among Police Officers.

Benyamina Douma N, Côté C, Lacasse A.

Spine (Phila Pa 1976). 2017 Oct 1;42(19):1485-1493. doi: 10.1097/BRS.0000000000002136.


Characterization of pathogenesis of and immune response to Burkholderia pseudomallei K96243 using both inhalational and intraperitoneal infection models in BALB/c and C57BL/6 mice.

Bearss JJ, Hunter M, Dankmeyer JL, Fritts KA, Klimko CP, Weaver CH, Shoe JL, Quirk AV, Toothman RG, Webster WM, Fetterer DP, Bozue JA, Worsham PL, Welkos SL, Amemiya K, Cote CK.

PLoS One. 2017 Feb 24;12(2):e0172627. doi: 10.1371/journal.pone.0172627. eCollection 2017.


Comparison of sampling methods to recover germinated Bacillus anthracis and Bacillus thuringiensis endospores from surface coupons.

Mott TM, Shoe JL, Hunter M, Woodson AM, Fritts KA, Klimko CP, Quirk AV, Welkos SL, Cote CK.

J Appl Microbiol. 2017 May;122(5):1219-1232. doi: 10.1111/jam.13418. Epub 2017 Apr 3.


Two stable variants of Burkholderia pseudomallei strain MSHR5848 express broadly divergent in vitro phenotypes associated with their virulence differences.

Shea AA, Bernhards RC, Cote CK, Chase CJ, Koehler JW, Klimko CP, Ladner JT, Rozak DA, Wolcott MJ, Fetterer DP, Kern SJ, Koroleva GI, Lovett SP, Palacios GF, Toothman RG, Bozue JA, Worsham PL, Welkos SL.

PLoS One. 2017 Feb 10;12(2):e0171363. doi: 10.1371/journal.pone.0171363. eCollection 2017. Erratum in: PLoS One. 2019 Apr 4;14(4):e0215200.


Prévenir la dénutrition des personnes âgées dysphagiques institutionnalisées avec une alimentation à textures adaptées : essai clinique randomisé.

Côté C, Payette H, Gagnon C.

Can J Diet Pract Res. 2017 Mar;78(1):45-49. doi: 10.3148/cjdpr-2016-031. Epub 2017 Feb 1. French. No abstract available.


Transapical Cannulation Through a Transcatheter Aortic Valve Implantation Valve: A Novel Approach for Cardiogenic Collapse.

Tremblay LP, Cote C, Pelletier MP.

Semin Thorac Cardiovasc Surg. 2016 Summer;28(2):400-402. doi: 10.1053/j.semtcvs.2016.05.012. Epub 2016 Jun 11.


The International Human Epigenome Consortium Data Portal.

Bujold D, Morais DAL, Gauthier C, Côté C, Caron M, Kwan T, Chen KC, Laperle J, Markovits AN, Pastinen T, Caron B, Veilleux A, Jacques PÉ, Bourque G.

Cell Syst. 2016 Nov 23;3(5):496-499.e2. doi: 10.1016/j.cels.2016.10.019. Epub 2016 Nov 15.


MHC class I-associated peptides derive from selective regions of the human genome.

Pearson H, Daouda T, Granados DP, Durette C, Bonneil E, Courcelles M, Rodenbrock A, Laverdure JP, Côté C, Mader S, Lemieux S, Thibault P, Perreault C.

J Clin Invest. 2016 Dec 1;126(12):4690-4701. doi: 10.1172/JCI88590. Epub 2016 Nov 14.


The Use of Epinephrine in Caudal Anesthesia Increases Stroke Volume and Cardiac Output in Children.

Liu CA, Sui J, Coté CJ, Anderson TA.

Reg Anesth Pain Med. 2016 Nov/Dec;41(6):780-786.


Characterization of in vitro phenotypes of Burkholderia pseudomallei and Burkholderia mallei strains potentially associated with persistent infection in mice.

Bernhards RC, Cote CK, Amemiya K, Waag DM, Klimko CP, Worsham PL, Welkos SL.

Arch Microbiol. 2017 Mar;199(2):277-301. doi: 10.1007/s00203-016-1303-8. Epub 2016 Oct 13.

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