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Items: 5

1.

T cells translate individual, quantal activation into collective, analog cytokine responses via time-integrated feedbacks.

Tkach KE, Barik D, Voisinne G, Malandro N, Hathorn MM, Cotari JW, Vogel R, Merghoub T, Wolchok J, Krichevsky O, Altan-Bonnet G.

Elife. 2014 Apr 9;3:e01944. doi: 10.7554/eLife.01944.

2.

Multidimensional single-cell analysis of BCR signaling reveals proximal activation defect as a hallmark of chronic lymphocytic leukemia B cells.

Palomba ML, Piersanti K, Ziegler CG, Decker H, Cotari JW, Bantilan K, Rijo I, Gardner JR, Heaney M, Bemis D, Balderas R, Malek SN, Seymour E, Zelenetz AD, van den Brink MR, Altan-Bonnet G.

PLoS One. 2014 Jan 29;9(1):e79987. doi: 10.1371/journal.pone.0079987. eCollection 2014.

3.

Diversity training for signal transduction: leveraging cell-to-cell variability to dissect cellular signaling, differentiation and death.

Cotari JW, Voisinne G, Altan-Bonnet G.

Curr Opin Biotechnol. 2013 Aug;24(4):760-6. doi: 10.1016/j.copbio.2013.05.002. Epub 2013 Jun 7. Review.

4.

Cell-to-cell variability analysis dissects the plasticity of signaling of common γ chain cytokines in T cells.

Cotari JW, Voisinne G, Dar OE, Karabacak V, Altan-Bonnet G.

Sci Signal. 2013 Mar 12;6(266):ra17. doi: 10.1126/scisignal.2003240.

5.

Human Langerhans cells use an IL-15R-α/IL-15/pSTAT5-dependent mechanism to break T-cell tolerance against the self-differentiation tumor antigen WT1.

Romano E, Cotari JW, Barreira da Silva R, Betts BC, Chung DJ, Avogadri F, Fink MJ, St Angelo ET, Mehrara B, Heller G, Münz C, Altan-Bonnet G, Young JW.

Blood. 2012 May 31;119(22):5182-90. doi: 10.1182/blood-2011-09-382200. Epub 2012 Apr 17.

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