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Items: 1 to 50 of 70

1.

POMC Neurons Dysfunction in Diet-induced Metabolic Disease: Hallmark or Mechanism of Disease?

Quarta C, Fioramonti X, Cota D.

Neuroscience. 2019 Nov 2. pii: S0306-4522(19)30676-1. doi: 10.1016/j.neuroscience.2019.09.031. [Epub ahead of print] Review.

PMID:
31689486
2.

Effects of a High-Protein/Moderate-Carbohydrate Diet on Appetite, Gut Peptides, and Endocannabinoids-A Preview Study.

Tischmann L, Drummen M, Gatta-Cherifi B, Raben A, Fogelholm M, Hartmann B, Holst JJ, Matias I, Cota D, Mensink RP, Joris PJ, Westerterp-Plantenga MS, Adam TC.

Nutrients. 2019 Sep 21;11(10). pii: E2269. doi: 10.3390/nu11102269.

3.

mTORC1 and CB1 receptor signaling regulate excitatory glutamatergic inputs onto the hypothalamic paraventricular nucleus in response to energy availability.

Mazier W, Saucisse N, Simon V, Cannich A, Marsicano G, Massa F, Cota D.

Mol Metab. 2019 Oct;28:151-159. doi: 10.1016/j.molmet.2019.08.005. Epub 2019 Aug 8.

4.

The gliotransmitter ACBP controls feeding and energy homeostasis via the melanocortin system.

Bouyakdan K, Martin H, Liénard F, Budry L, Taib B, Rodaros D, Chrétien C, Biron É, Husson Z, Cota D, Pénicaud L, Fulton S, Fioramonti X, Alquier T.

J Clin Invest. 2019 Apr 2;129(6):2417-2430. doi: 10.1172/JCI123454.

5.

Oea Signaling Pathways and the Metabolic Benefits of Vertical Sleeve Gastrectomy.

Hutch CR, Trakimas DR, Roelofs K, Pressler J, Sorrell J, Cota D, Obici S, Sandoval DA.

Ann Surg. 2020 Mar;271(3):509-518. doi: 10.1097/SLA.0000000000003093.

PMID:
30702457
6.

Sequential alteration of microglia and astrocytes in the rat thalamus following spinal nerve ligation.

Blaszczyk L, Maître M, Lesté-Lasserre T, Clark S, Cota D, Oliet SHR, Fénelon VS.

J Neuroinflammation. 2018 Dec 20;15(1):349. doi: 10.1186/s12974-018-1378-z.

7.

Beneficial role of Terminalia arjuna hydro-alcoholic extract in colitis and its possible mechanism.

Cota D, Mishra S, Shengule S.

J Ethnopharmacol. 2019 Feb 10;230:117-125. doi: 10.1016/j.jep.2018.10.020. Epub 2018 Oct 24.

PMID:
30367989
8.

NPV-BSK805, an Antineoplastic Jak2 Inhibitor Effective in Myeloproliferative Disorders, Causes Adiposity in Mice by Interfering With the Action of Leptin.

Haissaguerre M, Ferriere A, Clark S, Guzman-Quevedo O, Tabarin A, Cota D.

Front Pharmacol. 2018 May 15;9:527. doi: 10.3389/fphar.2018.00527. eCollection 2018.

9.

mTORC1-dependent increase in oxidative metabolism in POMC neurons regulates food intake and action of leptin.

Haissaguerre M, Ferrière A, Simon V, Saucisse N, Dupuy N, André C, Clark S, Guzman-Quevedo O, Tabarin A, Cota D.

Mol Metab. 2018 Jun;12:98-106. doi: 10.1016/j.molmet.2018.04.002. Epub 2018 Apr 13.

10.

mTORC1 pathway disruption abrogates the effects of the ciliary neurotrophic factor on energy balance and hypothalamic neuroinflammation.

André C, Catania C, Remus-Borel J, Ladeveze E, Leste-Lasserre T, Mazier W, Binder E, Gonzales D, Clark S, Guzman-Quevedo O, Abrous DN, Layé S, Cota D.

Brain Behav Immun. 2018 May;70:325-334. doi: 10.1016/j.bbi.2018.03.014. Epub 2018 Mar 13.

PMID:
29548998
11.

Liver Reptin/RUVBL2 controls glucose and lipid metabolism with opposite actions on mTORC1 and mTORC2 signalling.

Javary J, Allain-Courtois N, Saucisse N, Costet P, Heraud C, Benhamed F, Pierre R, Bure C, Pallares-Lupon N, Do Cruzeiro M, Postic C, Cota D, Dubus P, Rosenbaum J, Benhamouche-Trouillet S.

Gut. 2018 Dec;67(12):2192-2203. doi: 10.1136/gutjnl-2017-314208. Epub 2017 Oct 26.

PMID:
29074727
12.

Adipocyte cannabinoid receptor CB1 regulates energy homeostasis and alternatively activated macrophages.

Ruiz de Azua I, Mancini G, Srivastava RK, Rey AA, Cardinal P, Tedesco L, Zingaretti CM, Sassmann A, Quarta C, Schwitter C, Conrad A, Wettschureck N, Vemuri VK, Makriyannis A, Hartwig J, Mendez-Lago M, Bindila L, Monory K, Giordano A, Cinti S, Marsicano G, Offermanns S, Nisoli E, Pagotto U, Cota D, Lutz B.

J Clin Invest. 2017 Nov 1;127(11):4148-4162. doi: 10.1172/JCI83626. Epub 2017 Oct 16.

13.

The brain strikes back: Hypothalamic targets for peripheral CB1 receptor inverse agonism.

Cota D.

Mol Metab. 2017 Oct;6(10):1077-1078. doi: 10.1016/j.molmet.2017.07.003. Epub 2017 Jul 12. No abstract available.

14.

Molecular Integration of Incretin and Glucocorticoid Action Reverses Immunometabolic Dysfunction and Obesity.

Quarta C, Clemmensen C, Zhu Z, Yang B, Joseph SS, Lutter D, Yi CX, Graf E, García-Cáceres C, Legutko B, Fischer K, Brommage R, Zizzari P, Franklin BS, Krueger M, Koch M, Vettorazzi S, Li P, Hofmann SM, Bakhti M, Bastidas-Ponce A, Lickert H, Strom TM, Gailus-Durner V, Bechmann I, Perez-Tilve D, Tuckermann J, Hrabě de Angelis M, Sandoval D, Cota D, Latz E, Seeley RJ, Müller TD, DiMarchi RD, Finan B, Tschöp MH.

Cell Metab. 2017 Oct 3;26(4):620-632.e6. doi: 10.1016/j.cmet.2017.08.023. Epub 2017 Sep 21.

15.

Endocannabinoid modulation of homeostatic and non-homeostatic feeding circuits.

Lau BK, Cota D, Cristino L, Borgland SL.

Neuropharmacology. 2017 Sep 15;124:38-51. doi: 10.1016/j.neuropharm.2017.05.033. Epub 2017 Jun 1. Review.

PMID:
28579186
16.

Islet Endothelial Cell: Friend and Foe.

Mazier W, Cota D.

Endocrinology. 2017 Feb 1;158(2):226-228. doi: 10.1210/en.2016-1925. No abstract available.

PMID:
28430925
17.

The CB1 Receptor as the Cornerstone of Exostasis.

Piazza PV, Cota D, Marsicano G.

Neuron. 2017 Mar 22;93(6):1252-1274. doi: 10.1016/j.neuron.2017.02.002. Review.

18.

MECHANISMS IN ENDOCRINOLOGY: Endocannabinoids and metabolism: past, present and future.

Simon V, Cota D.

Eur J Endocrinol. 2017 Jun;176(6):R309-R324. doi: 10.1530/EJE-16-1044. Epub 2017 Feb 28. Review.

PMID:
28246151
19.

Nutritional status-dependent endocannabinoid signalling regulates the integration of rat visceral information.

Khlaifia A, Matias I, Cota D, Tell F.

J Physiol. 2017 Jun 1;595(11):3267-3285. doi: 10.1113/JP273484. Epub 2017 Mar 27.

20.

Inhibiting Microglia Expansion Prevents Diet-Induced Hypothalamic and Peripheral Inflammation.

André C, Guzman-Quevedo O, Rey C, Rémus-Borel J, Clark S, Castellanos-Jankiewicz A, Ladeveze E, Leste-Lasserre T, Nadjar A, Abrous DN, Laye S, Cota D.

Diabetes. 2017 Apr;66(4):908-919. doi: 10.2337/db16-0586. Epub 2016 Nov 30.

21.

A cannabinoid link between mitochondria and memory.

Hebert-Chatelain E, Desprez T, Serrat R, Bellocchio L, Soria-Gomez E, Busquets-Garcia A, Pagano Zottola AC, Delamarre A, Cannich A, Vincent P, Varilh M, Robin LM, Terral G, García-Fernández MD, Colavita M, Mazier W, Drago F, Puente N, Reguero L, Elezgarai I, Dupuy JW, Cota D, Lopez-Rodriguez ML, Barreda-Gómez G, Massa F, Grandes P, Bénard G, Marsicano G.

Nature. 2016 Nov 24;539(7630):555-559. doi: 10.1038/nature20127. Epub 2016 Nov 9.

PMID:
27828947
22.

The cannabinoid CB1 receptor and mTORC1 signalling pathways interact to modulate glucose homeostasis in mice.

Bermudez-Silva FJ, Romero-Zerbo SY, Haissaguerre M, Ruz-Maldonado I, Lhamyani S, El Bekay R, Tabarin A, Marsicano G, Cota D.

Dis Model Mech. 2016 Jan;9(1):51-61. doi: 10.1242/dmm.020750. Epub 2015 Nov 12.

23.

The Endocannabinoid System: Pivotal Orchestrator of Obesity and Metabolic Disease.

Mazier W, Saucisse N, Gatta-Cherifi B, Cota D.

Trends Endocrinol Metab. 2015 Oct;26(10):524-537. doi: 10.1016/j.tem.2015.07.007. Review.

PMID:
26412154
24.

Endocannabinoids and Metabolic Disorders.

Gatta-Cherifi B, Cota D.

Handb Exp Pharmacol. 2015;231:367-91. doi: 10.1007/978-3-319-20825-1_13. Review.

PMID:
26408168
25.

New insights on the role of the endocannabinoid system in the regulation of energy balance.

Gatta-Cherifi B, Cota D.

Int J Obes (Lond). 2016 Feb;40(2):210-9. doi: 10.1038/ijo.2015.179. Epub 2015 Sep 16. Review.

PMID:
26374449
26.

[Role of the mTOR pathway in the central regulation of energy balance].

Haissaguerre M, Cota D.

Biol Aujourdhui. 2015;209(4):295-307. doi: 10.1051/jbio/2016009. Epub 2016 Mar 28. Review. French.

PMID:
27021048
27.

Cannabinoid type 1 (CB1) receptors on Sim1-expressing neurons regulate energy expenditure in male mice.

Cardinal P, Bellocchio L, Guzmán-Quevedo O, André C, Clark S, Elie M, Leste-Lasserre T, Gonzales D, Cannich A, Marsicano G, Cota D.

Endocrinology. 2015 Feb;156(2):411-8. doi: 10.1210/en.2014-1437. Epub 2014 Dec 2.

PMID:
25456065
28.

CB1 cannabinoid receptor in SF1-expressing neurons of the ventromedial hypothalamus determines metabolic responses to diet and leptin.

Cardinal P, André C, Quarta C, Bellocchio L, Clark S, Elie M, Leste-Lasserre T, Maitre M, Gonzales D, Cannich A, Pagotto U, Marsicano G, Cota D.

Mol Metab. 2014 Aug 1;3(7):705-16. doi: 10.1016/j.molmet.2014.07.004. eCollection 2014 Oct.

29.

The corticotrophin-releasing factor/urocortin system regulates white fat browning in mice through paracrine mechanisms.

Lu B, Diz-Chaves Y, Markovic D, Contarino A, Penicaud L, Fanelli F, Clark S, Lehnert H, Cota D, Grammatopoulos DK, Tabarin A.

Int J Obes (Lond). 2015 Mar;39(3):408-17. doi: 10.1038/ijo.2014.164. Epub 2014 Sep 5.

PMID:
25189177
30.

Influence of mTOR in energy and metabolic homeostasis.

Haissaguerre M, Saucisse N, Cota D.

Mol Cell Endocrinol. 2014 Nov;397(1-2):67-77. doi: 10.1016/j.mce.2014.07.015. Epub 2014 Aug 7. Review.

PMID:
25109278
31.

mTORC2, the "other" mTOR, is a new player in energy balance regulation.

Cota D.

Mol Metab. 2014 Apr 18;3(4):349-50. doi: 10.1016/j.molmet.2014.04.002. eCollection 2014 Jul. No abstract available.

32.

Cannabinoid type-1 receptors in the paraventricular nucleus of the hypothalamus inhibit stimulated food intake.

Soria-Gómez E, Massa F, Bellocchio L, Rueda-Orozco PE, Ciofi P, Cota D, Oliet SH, Prospéro-García O, Marsicano G.

Neuroscience. 2014 Mar 28;263:46-53. doi: 10.1016/j.neuroscience.2014.01.005. Epub 2014 Jan 13.

PMID:
24434770
33.

Astroglial CB1 cannabinoid receptors regulate leptin signaling in mouse brain astrocytes.

Bosier B, Bellocchio L, Metna-Laurent M, Soria-Gomez E, Matias I, Hebert-Chatelain E, Cannich A, Maitre M, Leste-Lasserre T, Cardinal P, Mendizabal-Zubiaga J, Canduela MJ, Reguero L, Hermans E, Grandes P, Cota D, Marsicano G.

Mol Metab. 2013 Aug 9;2(4):393-404. doi: 10.1016/j.molmet.2013.08.001. eCollection 2013.

34.

Leucine supplementation protects from insulin resistance by regulating adiposity levels.

Binder E, Bermúdez-Silva FJ, André C, Elie M, Romero-Zerbo SY, Leste-Lasserre T, Belluomo I, Duchampt A, Clark S, Aubert A, Mezzullo M, Fanelli F, Pagotto U, Layé S, Mithieux G, Cota D.

PLoS One. 2013 Sep 25;8(9):e74705. doi: 10.1371/journal.pone.0074705. eCollection 2013.

35.

Leucine supplementation modulates fuel substrates utilization and glucose metabolism in previously obese mice.

Binder E, Bermúdez-Silva FJ, Elie M, Leste-Lasserre T, Belluomo I, Clark S, Duchampt A, Mithieux G, Cota D.

Obesity (Silver Spring). 2014 Mar;22(3):713-20. doi: 10.1002/oby.20578. Epub 2013 Sep 5.

36.

Activation of the sympathetic nervous system mediates hypophagic and anxiety-like effects of CB₁ receptor blockade.

Bellocchio L, Soria-Gómez E, Quarta C, Metna-Laurent M, Cardinal P, Binder E, Cannich A, Delamarre A, Häring M, Martín-Fontecha M, Vega D, Leste-Lasserre T, Bartsch D, Monory K, Lutz B, Chaouloff F, Pagotto U, Guzman M, Cota D, Marsicano G.

Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):4786-91. doi: 10.1073/pnas.1218573110. Epub 2013 Mar 4.

37.

Coupling nutrient sensing to metabolic homoeostasis: the role of the mammalian target of rapamycin complex 1 pathway.

André C, Cota D.

Proc Nutr Soc. 2012 Nov;71(4):502-10. doi: 10.1017/S0029665112000754. Epub 2012 Aug 9. Review.

PMID:
22877732
38.

Endocannabinoids measurement in human saliva as potential biomarker of obesity.

Matias I, Gatta-Cherifi B, Tabarin A, Clark S, Leste-Lasserre T, Marsicano G, Piazza PV, Cota D.

PLoS One. 2012;7(7):e42399. doi: 10.1371/journal.pone.0042399. Epub 2012 Jul 31.

39.

Hypothalamic CB1 cannabinoid receptors regulate energy balance in mice.

Cardinal P, Bellocchio L, Clark S, Cannich A, Klugmann M, Lutz B, Marsicano G, Cota D.

Endocrinology. 2012 Sep;153(9):4136-43. doi: 10.1210/en.2012-1405. Epub 2012 Jul 9.

PMID:
22778221
40.

Cannabinoid receptor 1 (CB1) antagonism enhances glucose utilisation and activates brown adipose tissue in diet-induced obese mice.

Bajzer M, Olivieri M, Haas MK, Pfluger PT, Magrisso IJ, Foster MT, Tschöp MH, Krawczewski-Carhuatanta KA, Cota D, Obici S.

Diabetologia. 2011 Dec;54(12):3121-31. doi: 10.1007/s00125-011-2302-6. Epub 2011 Oct 11.

PMID:
21987346
41.

Simultaneous postprandial deregulation of the orexigenic endocannabinoid anandamide and the anorexigenic peptide YY in obesity.

Gatta-Cherifi B, Matias I, Vallée M, Tabarin A, Marsicano G, Piazza PV, Cota D.

Int J Obes (Lond). 2012 Jun;36(6):880-5. doi: 10.1038/ijo.2011.165. Epub 2011 Aug 16.

PMID:
21844878
42.

The role of the endocannabinoid system in the neuroendocrine regulation of energy balance.

Bermudez-Silva FJ, Cardinal P, Cota D.

J Psychopharmacol. 2012 Jan;26(1):114-24. doi: 10.1177/0269881111408458. Epub 2011 Aug 8. Review.

PMID:
21824982
43.

New fat and new neurons: endocannabinoids control neurogenesis in obesity (Commentary on Rivera et al.).

Cota D, Marsicano G.

Eur J Neurosci. 2011 May;33(9):1575-6. doi: 10.1111/j.1460-9568.2011.07684.x. No abstract available.

PMID:
21535244
44.

mTORC1 signaling in energy balance and metabolic disease.

Catania C, Binder E, Cota D.

Int J Obes (Lond). 2011 Jun;35(6):751-61. doi: 10.1038/ijo.2010.208. Epub 2010 Sep 28. Review.

PMID:
20877289
45.

CB(1) signaling in forebrain and sympathetic neurons is a key determinant of endocannabinoid actions on energy balance.

Quarta C, Bellocchio L, Mancini G, Mazza R, Cervino C, Braulke LJ, Fekete C, Latorre R, Nanni C, Bucci M, Clemens LE, Heldmaier G, Watanabe M, Leste-Lassere T, Maitre M, Tedesco L, Fanelli F, Reuss S, Klaus S, Srivastava RK, Monory K, Valerio A, Grandis A, De Giorgio R, Pasquali R, Nisoli E, Cota D, Lutz B, Marsicano G, Pagotto U.

Cell Metab. 2010 Apr 7;11(4):273-85. doi: 10.1016/j.cmet.2010.02.015.

46.

Bimodal control of stimulated food intake by the endocannabinoid system.

Bellocchio L, Lafenêtre P, Cannich A, Cota D, Puente N, Grandes P, Chaouloff F, Piazza PV, Marsicano G.

Nat Neurosci. 2010 Mar;13(3):281-3. doi: 10.1038/nn.2494. Epub 2010 Feb 7.

PMID:
20139974
47.

Complex regulation of mammalian target of rapamycin complex 1 in the basomedial hypothalamus by leptin and nutritional status.

Villanueva EC, Münzberg H, Cota D, Leshan RL, Kopp K, Ishida-Takahashi R, Jones JC, Fingar DC, Seeley RJ, Myers MG Jr.

Endocrinology. 2009 Oct;150(10):4541-51. doi: 10.1210/en.2009-0642. Epub 2009 Jul 23.

48.

Food intake-independent effects of CB1 antagonism on glucose and lipid metabolism.

Cota D, Sandoval DA, Olivieri M, Prodi E, D'Alessio DA, Woods SC, Seeley RJ, Obici S.

Obesity (Silver Spring). 2009 Aug;17(8):1641-5. doi: 10.1038/oby.2009.84. Epub 2009 Mar 26.

49.

Mammalian target of rapamycin complex 1 (mTORC1) signaling in energy balance and obesity.

Cota D.

Physiol Behav. 2009 Jul 14;97(5):520-4. doi: 10.1016/j.physbeh.2009.03.006. Epub 2009 Mar 16. Review.

PMID:
19296907
50.

Fatty acid synthase inhibitors modulate energy balance via mammalian target of rapamycin complex 1 signaling in the central nervous system.

Proulx K, Cota D, Woods SC, Seeley RJ.

Diabetes. 2008 Dec;57(12):3231-8. doi: 10.2337/db07-1690. Epub 2008 Sep 5.

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