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ClampFISH detects individual nucleic acid molecules using click chemistry-based amplification.

Rouhanifard SH, Mellis IA, Dunagin M, Bayatpour S, Jiang CL, Dardani I, Symmons O, Emert B, Torre E, Cote A, Sullivan A, Stamatoyannopoulos JA, Raj A.

Nat Biotechnol. 2018 Nov 12. doi: 10.1038/nbt.4286. [Epub ahead of print]


GNE-371, a Potent and Selective Chemical Probe for the Second Bromodomains of Human Transcription-Initiation-Factor TFIID Subunit 1 and Transcription-Initiation-Factor TFIID Subunit 1-like.

Wang S, Tsui V, Crawford TD, Audia JE, Burdick DJ, Beresini MH, Côté A, Cummings R, Duplessis M, Flynn EM, Hewitt MC, Huang HR, Jayaram H, Jiang Y, Joshi S, Murray J, Nasveschuk CG, Pardo E, Poy F, Romero FA, Tang Y, Taylor AM, Wang J, Xu Z, Zawadzke LE, Zhu X, Albrecht BK, Magnuson SR, Bellon S, Cochran AG.

J Med Chem. 2018 Oct 25;61(20):9301-9315. doi: 10.1021/acs.jmedchem.8b01225. Epub 2018 Oct 5.


Coronary artery intimal thickening and ventricular dynamics in pediatric heart transplant recipients.

Cote AT, Hosking M, Voss C, Human DG, Sandor GGS, Harris KC.

Congenit Heart Dis. 2018 Sep 5. doi: 10.1111/chd.12629. [Epub ahead of print]


Evaluation of the use of the Scale for the Assessment and Rating of Ataxia (SARA) in healthy volunteers and patients with schizophrenia.

Shaafi Kabiri N, Syed S, Bali T, Karlin DR, Binneman B, Tan Y, Steinman A, Cote AC, Thomas KC.

J Neurol Sci. 2018 Aug 15;391:40-44. doi: 10.1016/j.jns.2018.05.019. Epub 2018 May 24.


Therapeutic Potential of Adipose Stem Cells.

Sabol RA, Bowles AC, Côté A, Wise R, Pashos N, Bunnell BA.

Adv Exp Med Biol. 2018 Jul 27. doi: 10.1007/5584_2018_248. [Epub ahead of print]


Evolution of ARDS biomarkers: Will metabolomics be the answer?

Metwaly S, Cote A, Donnelly SJ, Banoei MM, Mourad AI, Winston BW.

Am J Physiol Lung Cell Mol Physiol. 2018 Oct 1;315(4):L526-L534. doi: 10.1152/ajplung.00074.2018. Epub 2018 Jun 28.


The accuracy of endorectal ultrasonography and high-resolution magnetic resonance imaging for restaging rectal cancer after neoadjuvant chemoradiotherapy.

Cote A, Florin FG, Mois E, Elisei R, Badea R, Mare C, Hajjar NA, Iancu C, Lebovici A.

Ann Ital Chir. 2018;89:168-176.


Mapping DNA damage-dependent genetic interactions in yeast via party mating and barcode fusion genetics.

Díaz-Mejía JJ, Celaj A, Mellor JC, Coté A, Balint A, Ho B, Bansal P, Shaeri F, Gebbia M, Weile J, Verby M, Karkhanina A, Zhang Y, Wong C, Rich J, Prendergast D, Gupta G, Öztürk S, Durocher D, Brown GW, Roth FP.

Mol Syst Biol. 2018 May 28;14(5):e7985. doi: 10.15252/msb.20177985.


Amino Acid Assisted Incorporation of Dye Molecules within Calcite Crystals.

Marzec B, Green DC, Holden MA, Coté AS, Ihli J, Khalid S, Kulak A, Walker D, Tang C, Duffy DM, Kim YY, Meldrum FC.

Angew Chem Int Ed Engl. 2018 Jul 9;57(28):8623-8628. doi: 10.1002/anie.201804365. Epub 2018 Jun 10.


Hypertension Canada's 2018 Guidelines for the Management of Hypertension in Pregnancy.

Butalia S, Audibert F, Côté AM, Firoz T, Logan AG, Magee LA, Mundle W, Rey E, Rabi DM, Daskalopoulou SS, Nerenberg KA; Hypertension Canada.

Can J Cardiol. 2018 May;34(5):526-531. doi: 10.1016/j.cjca.2018.02.021. Epub 2018 Mar 1.


Hypertension Canada's 2018 Guidelines for Diagnosis, Risk Assessment, Prevention, and Treatment of Hypertension in Adults and Children.

Nerenberg KA, Zarnke KB, Leung AA, Dasgupta K, Butalia S, McBrien K, Harris KC, Nakhla M, Cloutier L, Gelfer M, Lamarre-Cliche M, Milot A, Bolli P, Tremblay G, McLean D, Padwal RS, Tran KC, Grover S, Rabkin SW, Moe GW, Howlett JG, Lindsay P, Hill MD, Sharma M, Field T, Wein TH, Shoamanesh A, Dresser GK, Hamet P, Herman RJ, Burgess E, Gryn SE, Grégoire JC, Lewanczuk R, Poirier L, Campbell TS, Feldman RD, Lavoie KL, Tsuyuki RT, Honos G, Prebtani APH, Kline G, Schiffrin EL, Don-Wauchope A, Tobe SW, Gilbert RE, Leiter LA, Jones C, Woo V, Hegele RA, Selby P, Pipe A, McFarlane PA, Oh P, Gupta M, Bacon SL, Kaczorowski J, Trudeau L, Campbell NRC, Hiremath S, Roerecke M, Arcand J, Ruzicka M, Prasad GVR, Vallée M, Edwards C, Sivapalan P, Penner SB, Fournier A, Benoit G, Feber J, Dionne J, Magee LA, Logan AG, Côté AM, Rey E, Firoz T, Kuyper LM, Gabor JY, Townsend RR, Rabi DM, Daskalopoulou SS; Hypertension Canada.

Can J Cardiol. 2018 May;34(5):506-525. doi: 10.1016/j.cjca.2018.02.022. Epub 2018 Mar 1.


Notes from the Field: Assessing Rabies Risk After a Mass Bat Exposure at a Research Facility in a National Park - Wyoming, 2017.

Cote A, Guagliardo SAJ, Tran CH, Said MA, Pickens V, Musgrave K, Wallace R.

MMWR Morb Mortal Wkly Rep. 2018 Mar 16;67(10):313-314. doi: 10.15585/mmwr.mm6710a7. No abstract available.


Exercise and Asthma.

Côté A, Turmel J, Boulet LP.

Semin Respir Crit Care Med. 2018 Feb;39(1):19-28. doi: 10.1055/s-0037-1606215. Epub 2018 Feb 10.


A framework for exhaustively mapping functional missense variants.

Weile J, Sun S, Cote AG, Knapp J, Verby M, Mellor JC, Wu Y, Pons C, Wong C, van Lieshout N, Yang F, Tasan M, Tan G, Yang S, Fowler DM, Nussbaum R, Bloom JD, Vidal M, Hill DE, Aloy P, Roth FP.

Mol Syst Biol. 2017 Dec 21;13(12):957. doi: 10.15252/msb.20177908.


Intimal thickening at coronary bifurcations in pediatric heart transplant recipients.

Duncombe SL, Hosking MCK, Coté AT, Voss C, Harris KC.

Pediatr Transplant. 2018 Mar;22(2). doi: 10.1111/petr.13100. Epub 2017 Dec 19.


Premature Termination of Psychotherapy in Patients With Borderline Personality Disorder: A Cluster-Analytic Study.

Gamache D, Savard C, Lemelin S, Côté A, Villeneuve É.

J Nerv Ment Dis. 2018 Apr;206(4):231-238. doi: 10.1097/NMD.0000000000000764.


Non-linear Heart Rate and Blood Pressure Interaction in Response to Lower-Body Negative Pressure.

Verma AK, Xu D, Garg A, Cote AT, Goswami N, Blaber AP, Tavakolian K.

Front Physiol. 2017 Oct 24;8:767. doi: 10.3389/fphys.2017.00767. eCollection 2017.


Interventional magnetic resonance imaging guided carotid embolectomy using a novel resonant marker catheter: demonstration of preclinical feasibility.

Yang JK, Cote AM, Jordan CD, Kondapavulur S, Losey AD, McCoy D, Chu A, Yu JF, Moore T, Stillson C, Settecase F, Alexander MD, Nicholson A, Cooke DL, Saeed M, Barry D, Martin AJ, Wilson MW, Hetts SW.

Biomed Microdevices. 2017 Sep 25;19(4):88. doi: 10.1007/s10544-017-0225-9.


Premature psychotherapy termination in an outpatient treatment program for personality disorders: a survival analysis.

Gamache D, Savard C, Lemelin S, Côté A, Villeneuve E.

Compr Psychiatry. 2018 Jan;80:14-23. doi: 10.1016/j.comppsych.2017.08.001. Epub 2017 Aug 9.


Mitotic transcription and waves of gene reactivation during mitotic exit.

Palozola KC, Donahue G, Liu H, Grant GR, Becker JS, Cote A, Yu H, Raj A, Zaret KS.

Science. 2017 Oct 6;358(6359):119-122. doi: 10.1126/science.aal4671. Epub 2017 Sep 14.


Assessing predictions of fitness effects of missense mutations in SUMO-conjugating enzyme UBE2I.

Zhang J, Kinch LN, Cong Q, Weile J, Sun S, Cote AG, Roth FP, Grishin NV.

Hum Mutat. 2017 Sep;38(9):1051-1063. doi: 10.1002/humu.23293.


GNE-886: A Potent and Selective Inhibitor of the Cat Eye Syndrome Chromosome Region Candidate 2 Bromodomain (CECR2).

Crawford TD, Audia JE, Bellon S, Burdick DJ, Bommi-Reddy A, Côté A, Cummings RT, Duplessis M, Flynn EM, Hewitt M, Huang HR, Jayaram H, Jiang Y, Joshi S, Kiefer JR, Murray J, Nasveschuk CG, Neiss A, Pardo E, Romero FA, Sandy P, Sims RJ 3rd, Tang Y, Taylor AM, Tsui V, Wang J, Wang S, Wang Y, Xu Z, Zawadzke L, Zhu X, Albrecht BK, Magnuson SR, Cochran AG.

ACS Med Chem Lett. 2017 Jun 1;8(7):737-741. doi: 10.1021/acsmedchemlett.7b00132. eCollection 2017 Jul 13.


A Systematic Review of Infective Endocarditis in Patients With Bovine Jugular Vein Valves Compared With Other Valve Types.

Sharma A, Cote AT, Hosking MCK, Harris KC.

JACC Cardiovasc Interv. 2017 Jul 24;10(14):1449-1458. doi: 10.1016/j.jcin.2017.04.025. Review.


Inhibition of bromodomain-containing protein 9 for the prevention of epigenetically-defined drug resistance.

Crawford TD, Vartanian S, Côté A, Bellon S, Duplessis M, Flynn EM, Hewitt M, Huang HR, Kiefer JR, Murray J, Nasveschuk CG, Pardo E, Romero FA, Sandy P, Tang Y, Taylor AM, Tsui V, Wang J, Wang S, Zawadzke L, Albrecht BK, Magnuson SR, Cochran AG, Stokoe D.

Bioorg Med Chem Lett. 2017 Aug 1;27(15):3534-3541. doi: 10.1016/j.bmcl.2017.05.063. Epub 2017 Jun 3.


A Doppler Echocardiographic Study of the Myocardial Inotropic Response to Peak Semisupine Exercise in Healthy Children: Development of a Simplified Index of Myocardial Reserve.

Cote AT, Duff DK, Escudero CA, De Souza AM, Williams LD, Gill R, Zadorsky MT, Harris KC, Potts JE, Sandor GGS.

J Am Soc Echocardiogr. 2017 Aug;30(8):790-796. doi: 10.1016/j.echo.2017.04.008. Epub 2017 Jun 7.


Hypertension Canada's 2017 Guidelines for Diagnosis, Risk Assessment, Prevention, and Treatment of Hypertension in Adults.

Leung AA, Daskalopoulou SS, Dasgupta K, McBrien K, Butalia S, Zarnke KB, Nerenberg K, Harris KC, Nakhla M, Cloutier L, Gelfer M, Lamarre-Cliche M, Milot A, Bolli P, Tremblay G, McLean D, Tran KC, Tobe SW, Ruzicka M, Burns KD, Vallée M, Prasad GVR, Gryn SE, Feldman RD, Selby P, Pipe A, Schiffrin EL, McFarlane PA, Oh P, Hegele RA, Khara M, Wilson TW, Penner SB, Burgess E, Sivapalan P, Herman RJ, Bacon SL, Rabkin SW, Gilbert RE, Campbell TS, Grover S, Honos G, Lindsay P, Hill MD, Coutts SB, Gubitz G, Campbell NRC, Moe GW, Howlett JG, Boulanger JM, Prebtani A, Kline G, Leiter LA, Jones C, Côté AM, Woo V, Kaczorowski J, Trudeau L, Tsuyuki RT, Hiremath S, Drouin D, Lavoie KL, Hamet P, Grégoire JC, Lewanczuk R, Dresser GK, Sharma M, Reid D, Lear SA, Moullec G, Gupta M, Magee LA, Logan AG, Dionne J, Fournier A, Benoit G, Feber J, Poirier L, Padwal RS, Rabi DM; Hypertension Canada.

Can J Cardiol. 2017 May;33(5):557-576. doi: 10.1016/j.cjca.2017.03.005. Epub 2017 Mar 10. Erratum in: Can J Cardiol. 2017 Dec;33(12 ):1733-1734.


FISHing Out the Details of CRISPR Genome Tracks.

Coté AJ, Raj A.

Biophys J. 2017 Mar 28;112(6):1045-1046. doi: 10.1016/j.bpj.2017.02.006. No abstract available.


Visual or automated dipstick testing for proteinuria in pregnancy?

Correa ME, Côté AM, De Silva DA, Wang L, Packianathan P, von Dadelszen P, Magee LA.

Pregnancy Hypertens. 2017 Jan;7:50-53. doi: 10.1016/j.preghy.2017.01.005. Epub 2017 Jan 23.


The influence of circumferential resection margins on survival following rectal cancer surgery.

Mois E, Graur F, Hajjar NA, Puia C, Cote A, Zaharie F, Bartos A, Momani NA, Pop F, Neagos H, Ciorogar G, Iancu C.

Ann Ital Chir. 2017;88. pii: S0003469X16026300.


Optimization of an endovascular magnetic filter for maximized capture of magnetic nanoparticles.

Kondapavulur S, Cote AM, Neumann KD, Jordan CD, McCoy D, Mabray MC, Liu D, Sze CH, Gautam A, VanBrocklin HF, Wilson M, Hetts SW.

Biomed Microdevices. 2016 Dec;18(6):109.


Asthma and exercise-induced respiratory symptoms in the athlete: new insights.

Boulet LP, Turmel J, Côté A.

Curr Opin Pulm Med. 2017 Jan;23(1):71-77. Review.


Exploring genetic suppression interactions on a global scale.

van Leeuwen J, Pons C, Mellor JC, Yamaguchi TN, Friesen H, Koschwanez J, Ušaj MM, Pechlaner M, Takar M, Ušaj M, VanderSluis B, Andrusiak K, Bansal P, Baryshnikova A, Boone CE, Cao J, Cote A, Gebbia M, Horecka G, Horecka I, Kuzmin E, Legro N, Liang W, van Lieshout N, McNee M, San Luis BJ, Shaeri F, Shuteriqi E, Sun S, Yang L, Youn JY, Yuen M, Costanzo M, Gingras AC, Aloy P, Oostenbrink C, Murray A, Graham TR, Myers CL, Andrews BJ, Roth FP, Boone C.

Science. 2016 Nov 4;354(6312). pii: aag0839.


Influence of Calcium on the Initial Stages of the Sol-Gel Synthesis of Bioactive Glasses.

Côté AS, Cormack AN, Tilocca A.

J Phys Chem B. 2016 Nov 17;120(45):11773-11780. Epub 2016 Nov 3.


Discovery of a Potent and Selective in Vivo Probe (GNE-272) for the Bromodomains of CBP/EP300.

Crawford TD, Romero FA, Lai KW, Tsui V, Taylor AM, de Leon Boenig G, Noland CL, Murray J, Ly J, Choo EF, Hunsaker TL, Chan EW, Merchant M, Kharbanda S, Gascoigne KE, Kaufman S, Beresini MH, Liao J, Liu W, Chen KX, Chen Z, Conery AR, Côté A, Jayaram H, Jiang Y, Kiefer JR, Kleinheinz T, Li Y, Maher J, Pardo E, Poy F, Spillane KL, Wang F, Wang J, Wei X, Xu Z, Xu Z, Yen I, Zawadzke L, Zhu X, Bellon S, Cummings R, Cochran AG, Albrecht BK, Magnuson S.

J Med Chem. 2016 Dec 8;59(23):10549-10563. Epub 2016 Sep 28.


Obstetric medical care in Canada.

Magee LA, Cote AM, Joseph G, Firoz T, Sia W.

Obstet Med. 2016 Sep;9(3):117-9. doi: 10.1177/1753495X16645730. Epub 2016 May 12.


Persistent Insulin Resistance in Podocytes Caused by Epigenetic Changes of SHP-1 in Diabetes.

Lizotte F, Denhez B, Guay A, Gévry N, Côté AM, Geraldes P.

Diabetes. 2016 Dec;65(12):3705-3717. Epub 2016 Sep 1.


Ultimate journey of the terminally ill: Ways and pathways of hope.

Daneault S, Lussier V, Mongeau S, Yelle L, Côté A, Sicotte C, Paillé P, Dion D, Coulombe M.

Can Fam Physician. 2016 Aug;62(8):648-56.


Outcome Following Surgical Interventions for Micrognathia in Infants With Pierre Robin Sequence: A Systematic Review of the Literature.

Almajed A, Viezel-Mathieu A, Gilardino MS, Flores RL, Tholpady SS, Côté A.

Cleft Palate Craniofac J. 2017 Jan;54(1):32-42. doi: 10.1597/15-282. Epub 2016 Jul 14. Review.


Nanoscale imaging of RNA with expansion microscopy.

Chen F, Wassie AT, Cote AJ, Sinha A, Alon S, Asano S, Daugharthy ER, Chang JB, Marblestone A, Church GM, Raj A, Boyden ES.

Nat Methods. 2016 Aug;13(8):679-84. doi: 10.1038/nmeth.3899. Epub 2016 Jul 4.


Strain-relief by single dislocation loops in calcite crystals grown on self-assembled monolayers.

Ihli J, Clark JN, Côté AS, Kim YY, Schenk AS, Kulak AN, Comyn TP, Chammas O, Harder RJ, Duffy DM, Robinson IK, Meldrum FC.

Nat Commun. 2016 Jun 15;7:11878. doi: 10.1038/ncomms11878.


Diving into the Water: Inducible Binding Conformations for BRD4, TAF1(2), BRD9, and CECR2 Bromodomains.

Crawford TD, Tsui V, Flynn EM, Wang S, Taylor AM, Côté A, Audia JE, Beresini MH, Burdick DJ, Cummings R, Dakin LA, Duplessis M, Good AC, Hewitt MC, Huang HR, Jayaram H, Kiefer JR, Jiang Y, Murray J, Nasveschuk CG, Pardo E, Poy F, Romero FA, Tang Y, Wang J, Xu Z, Zawadzke LE, Zhu X, Albrecht BK, Magnuson SR, Bellon S, Cochran AG.

J Med Chem. 2016 Jun 9;59(11):5391-402. doi: 10.1021/acs.jmedchem.6b00264. Epub 2016 May 31.


Fragment-Based Discovery of a Selective and Cell-Active Benzodiazepinone CBP/EP300 Bromodomain Inhibitor (CPI-637).

Taylor AM, Côté A, Hewitt MC, Pastor R, Leblanc Y, Nasveschuk CG, Romero FA, Crawford TD, Cantone N, Jayaram H, Setser J, Murray J, Beresini MH, de Leon Boenig G, Chen Z, Conery AR, Cummings RT, Dakin LA, Flynn EM, Huang OW, Kaufman S, Keller PJ, Kiefer JR, Lai T, Li Y, Liao J, Liu W, Lu H, Pardo E, Tsui V, Wang J, Wang Y, Xu Z, Yan F, Yu D, Zawadzke L, Zhu X, Zhu X, Sims RJ 3rd, Cochran AG, Bellon S, Audia JE, Magnuson S, Albrecht BK.

ACS Med Chem Lett. 2016 Mar 15;7(5):531-6. doi: 10.1021/acsmedchemlett.6b00075. eCollection 2016 May 12.


Pooled-matrix protein interaction screens using Barcode Fusion Genetics.

Yachie N, Petsalaki E, Mellor JC, Weile J, Jacob Y, Verby M, Ozturk SB, Li S, Cote AG, Mosca R, Knapp JJ, Ko M, Yu A, Gebbia M, Sahni N, Yi S, Tyagi T, Sheykhkarimli D, Roth JF, Wong C, Musa L, Snider J, Liu YC, Yu H, Braun P, Stagljar I, Hao T, Calderwood MA, Pelletier L, Aloy P, Hill DE, Vidal M, Roth FP.

Mol Syst Biol. 2016 Apr 22;12(4):863. doi: 10.15252/msb.20156660.


Regulatory T Cell Modulation by CBP/EP300 Bromodomain Inhibition.

Ghosh S, Taylor A, Chin M, Huang HR, Conery AR, Mertz JA, Salmeron A, Dakle PJ, Mele D, Cote A, Jayaram H, Setser JW, Poy F, Hatzivassiliou G, DeAlmeida-Nagata D, Sandy P, Hatton C, Romero FA, Chiang E, Reimer T, Crawford T, Pardo E, Watson VG, Tsui V, Cochran AG, Zawadzke L, Harmange JC, Audia JE, Bryant BM, Cummings RT, Magnuson SR, Grogan JL, Bellon SF, Albrecht BK, Sims RJ 3rd, Lora JM.

J Biol Chem. 2016 Jun 17;291(25):13014-27. doi: 10.1074/jbc.M115.708560. Epub 2016 Apr 7.


Discovery of Benzotriazolo[4,3-d][1,4]diazepines as Orally Active Inhibitors of BET Bromodomains.

Taylor AM, Vaswani RG, Gehling VS, Hewitt MC, Leblanc Y, Audia JE, Bellon S, Cummings RT, Côté A, Harmange JC, Jayaram H, Joshi S, Lora JM, Mertz JA, Neiss A, Pardo E, Nasveschuk CG, Poy F, Sandy P, Setser JW, Sims RJ 3rd, Tang Y, Albrecht BK.

ACS Med Chem Lett. 2015 Mar 25;7(2):145-50. doi: 10.1021/ml500411h. eCollection 2016 Feb 11.


Single-cell differences in matrix gene expression do not predict matrix deposition.

Cote AJ, McLeod CM, Farrell MJ, McClanahan PD, Dunagin MC, Raj A, Mauck RL.

Nat Commun. 2016 Mar 3;7:10865. doi: 10.1038/ncomms10865.


Neonatal intensive care unit discharge of infants with cardiorespiratory events: Tri-country comparison of academic centers.

Carlos C, Hageman J, Pellerite M, McEntire B, Cóté A, Raoux A, Franco P, Rusciolelli C, Consenstein L, Kelly D.

J Neonatal Perinatal Med. 2015;8(4):307-11. doi: 10.3233/NPM-15814077.


Identification of a Benzoisoxazoloazepine Inhibitor (CPI-0610) of the Bromodomain and Extra-Terminal (BET) Family as a Candidate for Human Clinical Trials.

Albrecht BK, Gehling VS, Hewitt MC, Vaswani RG, Côté A, Leblanc Y, Nasveschuk CG, Bellon S, Bergeron L, Campbell R, Cantone N, Cooper MR, Cummings RT, Jayaram H, Joshi S, Mertz JA, Neiss A, Normant E, O'Meara M, Pardo E, Poy F, Sandy P, Supko J, Sims RJ 3rd, Harmange JC, Taylor AM, Audia JE.

J Med Chem. 2016 Feb 25;59(4):1330-9. doi: 10.1021/acs.jmedchem.5b01882. Epub 2016 Feb 4.


[Regulators in access to anticancer drugs in Canada].

Côté A, Keating B, Parent M, Simard G.

Sante Publique. 2015 Jul-Aug;27(4):515-27. French.


The accuracy of endorectal ultrasonography in rectal cancer staging.

Cote A, Graur F, Lebovici A, Mois E, Al Hajjar N, Mare C, Badea R, Iancu C.

Clujul Med. 2015;88(3):348-56. doi: 10.15386/cjmed-481. Epub 2015 Jul 1.

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