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Items: 21


Genetic dissection of Nodal and Bmp signalling requirements during primordial germ cell development in mouse.

Senft AD, Bikoff EK, Robertson EJ, Costello I.

Nat Commun. 2019 Mar 6;10(1):1089. doi: 10.1038/s41467-019-09052-w.


Combinatorial Smad2/3 Activities Downstream of Nodal Signaling Maintain Embryonic/Extra-Embryonic Cell Identities during Lineage Priming.

Senft AD, Costello I, King HW, Mould AW, Bikoff EK, Robertson EJ.

Cell Rep. 2018 Aug 21;24(8):1977-1985.e7. doi: 10.1016/j.celrep.2018.07.077.


From expert to novice.

Costello I.

Br J Nurs. 2018 Mar 22;27(6):288. doi: 10.12968/bjon.2018.27.6.288. No abstract available.


Stability of vincristine sulfate, doxorubicin hydrochloride and etoposide phosphate admixtures in polyisoprene elastomeric pump supporting transition of the EPOCH regimen to outpatient care.

Svirskis D, Behera S, Naidoo N, Beachman J, Raina T, Zhou Y, Berkahn L, Costello I, Gu Y.

J Oncol Pharm Pract. 2019 Jun;25(4):831-840. doi: 10.1177/1078155218764285. Epub 2018 Mar 14.


Functional characterisation of cis-regulatory elements governing dynamic Eomes expression in the early mouse embryo.

Simon CS, Downes DJ, Gosden ME, Telenius J, Higgs DR, Hughes JR, Costello I, Bikoff EK, Robertson EJ.

Development. 2017 Apr 1;144(7):1249-1260. doi: 10.1242/dev.147322. Epub 2017 Feb 7.


Lhx1 functions together with Otx2, Foxa2, and Ldb1 to govern anterior mesendoderm, node, and midline development.

Costello I, Nowotschin S, Sun X, Mould AW, Hadjantonakis AK, Bikoff EK, Robertson EJ.

Genes Dev. 2015 Oct 15;29(20):2108-22. doi: 10.1101/gad.268979.115.


Constraint of gene expression by the chromatin remodelling protein CHD4 facilitates lineage specification.

O'Shaughnessy-Kirwan A, Signolet J, Costello I, Gharbi S, Hendrich B.

Development. 2015 Aug 1;142(15):2586-97. doi: 10.1242/dev.125450. Epub 2015 Jun 26.


The PR/SET domain zinc finger protein Prdm4 regulates gene expression in embryonic stem cells but plays a nonessential role in the developing mouse embryo.

Bogani D, Morgan MA, Nelson AC, Costello I, McGouran JF, Kessler BM, Robertson EJ, Bikoff EK.

Mol Cell Biol. 2013 Oct;33(19):3936-50. doi: 10.1128/MCB.00498-13. Epub 2013 Aug 5.


The T-box transcription factor Eomesodermin is essential for AVE induction in the mouse embryo.

Nowotschin S, Costello I, Piliszek A, Kwon GS, Mao CA, Klein WH, Robertson EJ, Hadjantonakis AK.

Genes Dev. 2013 May 1;27(9):997-1002. doi: 10.1101/gad.215152.113.


NuRD suppresses pluripotency gene expression to promote transcriptional heterogeneity and lineage commitment.

Reynolds N, Latos P, Hynes-Allen A, Loos R, Leaford D, O'Shaughnessy A, Mosaku O, Signolet J, Brennecke P, Kalkan T, Costello I, Humphreys P, Mansfield W, Nakagawa K, Strouboulis J, Behrens A, Bertone P, Hendrich B.

Cell Stem Cell. 2012 May 4;10(5):583-94. doi: 10.1016/j.stem.2012.02.020.


The T-box transcription factor Eomesodermin acts upstream of Mesp1 to specify cardiac mesoderm during mouse gastrulation.

Costello I, Pimeisl IM, Dräger S, Bikoff EK, Robertson EJ, Arnold SJ.

Nat Cell Biol. 2011 Aug 7;13(9):1084-91. doi: 10.1038/ncb2304.


Sporadic Creutzfeldt-Jakob disease: a rare cause of rapid cognitive decline in a patient with systemic lupus erythematosus.

Costello I, Phadke R, Shah N.

J R Coll Physicians Edinb. 2011 Mar;41(1):22-5. doi: 10.4997/JRCPE.2011.106.


The fibronectin leucine-rich repeat transmembrane protein Flrt2 is required in the epicardium to promote heart morphogenesis.

Müller PS, Schulz R, Maretto S, Costello I, Srinivas S, Bikoff E, Robertson E.

Development. 2011 Apr;138(7):1297-308. doi: 10.1242/dev.059386. Epub 2011 Feb 24.


Smad4-dependent pathways control basement membrane deposition and endodermal cell migration at early stages of mouse development.

Costello I, Biondi CA, Taylor JM, Bikoff EK, Robertson EJ.

BMC Dev Biol. 2009 Oct 22;9:54. doi: 10.1186/1471-213X-9-54.


The role of low intensity pulsed ultrasound therapy in the management of acute fractures: a systematic review.

Griffin XL, Costello I, Costa ML.

J Trauma. 2008 Dec;65(6):1446-52. doi: 10.1097/TA.0b013e318185e222. Review.


Keeping things quiet: roles of NuRD and Sin3 co-repressor complexes during mammalian development.

McDonel P, Costello I, Hendrich B.

Int J Biochem Cell Biol. 2009 Jan;41(1):108-16. doi: 10.1016/j.biocel.2008.07.022. Epub 2008 Aug 14. Review.


Chronic haloperidol or clozapine treatment does not alter parvalbumin immunoreactivity in the rat frontal cortex or hippocampus.

Cahir M, Costello I, King DJ, Reynolds GP.

Neurosci Lett. 2005 Jan 3;373(1):57-60.


A literature review to identify interventions to improve the use of medicines in children.

Costello I, Wong IC, Nunn AJ.

Child Care Health Dev. 2004 Nov;30(6):647-65. Review.


Oral cobalamin therapy.

Chalmers RA, Bain MD, Costello I.

Lancet. 2000 Jan 8;355(9198):148. No abstract available.


The economics of a pharmacy-based central intravenous additive service for paediatric patients.

Armour DJ, Cairns CJ, Costello I, Riley SJ, Davies EG.

Pharmacoeconomics. 1996 Oct;10(4):386-94.


Sodium glycerophosphate in the treatment of neonatal hypophosphataemia.

Costello I, Powell C, Williams AF.

Arch Dis Child Fetal Neonatal Ed. 1995 Jul;73(1):F44-5.

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