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Items: 36

1.

Ectopic Lck expression in CLL demarcates intratumoral subpopulations with aberrant B-cell receptor signaling.

Theofani E, Alexis S, Costeas P, Andriopoulos C, Feleskoura G, Zikos P, Aktypi A, Spyridonidis A, Nika K.

Blood Adv. 2018 Apr 24;2(8):877-882. doi: 10.1182/bloodadvances.2017015321. No abstract available.

2.

Combined effect of glutamine at position 70 of HLA-DRB1 and alanine at position 57 of HLA-DQB1 in type 1 diabetes: An epitope analysis.

Gerasimou P, Nicolaidou V, Skordis N, Picolos M, Monos D, Costeas PA.

PLoS One. 2018 Mar 1;13(3):e0193684. doi: 10.1371/journal.pone.0193684. eCollection 2018.

3.

JAK2 V617F hematopoietic clones are present several years prior to MPN diagnosis and follow different expansion kinetics.

McKerrell T, Park N, Chi J, Collord G, Moreno T, Ponstingl H, Dias J, Gerasimou P, Melanthiou K, Prokopiou C, Antoniades M, Varela I, Costeas PA, Vassiliou GS.

Blood Adv. 2017 Jun 12;1(14):968-971. doi: 10.1182/bloodadvances.2017007047. eCollection 2017 Jun 13. No abstract available.

4.

Simple in vitro generation of human leukocyte antigen-G-expressing T-regulatory cells through pharmacological hypomethylation for adoptive cellular immunotherapy against graft-versus-host disease.

Stamou P, Marioli D, Patmanidi AL, Sgourou A, Vittoraki A, Theofani E, Pierides C, Taraviras S, Costeas PA, Spyridonidis A.

Cytotherapy. 2017 Apr;19(4):521-530. doi: 10.1016/j.jcyt.2017.01.004. Epub 2017 Feb 2.

PMID:
28162915
5.

HLA-G variability and haplotypes detected by massively parallel sequencing procedures in the geographicaly distinct population samples of Brazil and Cyprus.

Castelli EC, Gerasimou P, Paz MA, Ramalho J, Porto IOP, Lima THA, Souza AS, Veiga-Castelli LC, Collares CVA, Donadi EA, Mendes-Junior CT, Costeas P.

Mol Immunol. 2017 Mar;83:115-126. doi: 10.1016/j.molimm.2017.01.020. Epub 2017 Jan 27.

PMID:
28135606
6.

Treatment and outcome of 2904 CML patients from the EUTOS population-based registry.

Hoffmann VS, Baccarani M, Hasford J, Castagnetti F, Di Raimondo F, Casado LF, Turkina A, Zackova D, Ossenkoppele G, Zaritskey A, Höglund M, Simonsson B, Indrak K, Sninska Z, Sacha T, Clark R, Bogdanovic A, Hellmann A, Griskevicius L, Schubert-Fritschle G, Sertic D, Guilhot J, Lejniece S, Zupan I, Burgstaller S, Koskenvesa P, Everaus H, Costeas P, Lindoerfer D, Rosti G, Saussele S, Hochhaus A, Hehlmann R.

Leukemia. 2017 Mar;31(3):593-601. doi: 10.1038/leu.2016.246. Epub 2016 Aug 29.

PMID:
27568522
7.

Eye on the B-ALL: B-cell receptor repertoires reveal persistence of numerous B-lymphoblastic leukemia subclones from diagnosis to relapse.

Bashford-Rogers RJ, Nicolaou KA, Bartram J, Goulden NJ, Loizou L, Koumas L, Chi J, Hubank M, Kellam P, Costeas PA, Vassiliou GS.

Leukemia. 2016 Dec;30(12):2312-2321. doi: 10.1038/leu.2016.142. Epub 2016 May 23.

8.

Development and validation of a comprehensive genomic diagnostic tool for myeloid malignancies.

McKerrell T, Moreno T, Ponstingl H, Bolli N, Dias JM, Tischler G, Colonna V, Manasse B, Bench A, Bloxham D, Herman B, Fletcher D, Park N, Quail MA, Manes N, Hodkinson C, Baxter J, Sierra J, Foukaneli T, Warren AJ, Chi J, Costeas P, Rad R, Huntly B, Grove C, Ning Z, Tyler-Smith C, Varela I, Scott M, Nomdedeu J, Mustonen V, Vassiliou GS.

Blood. 2016 Jul 7;128(1):e1-9. doi: 10.1182/blood-2015-11-683334. Epub 2016 Apr 27.

9.

HLA-G 14-bp polymorphism affects the age of onset in Type I Diabetes Mellitus.

Gerasimou P, Skordis N, Picolos M, Spyridonidis A, Costeas P.

Int J Immunogenet. 2016 Jun;43(3):135-42. doi: 10.1111/iji.12259. Epub 2016 Apr 15.

PMID:
27080982
10.

SPARC ectopic overexpression inhibits growth and promotes programmed cell death in acute myeloid leukemia transformed from myelodysplastic syndrome cells, alone and in combination with Ara-C treatment.

Nian Q, Chi J, Xiao Q, Wei C, Costeas P, Yang Z, Liu L, Wang L.

Oncol Rep. 2015 Sep;34(3):1406-14. doi: 10.3892/or.2015.4114. Epub 2015 Jul 8.

PMID:
26165695
11.

Gene expression changes in HLA mismatched mixed lymphocyte cultures reveal genes associated with allorecognition.

Nicolaidou V, Stylianou C, Koumas L, Vassiliou GS, Bodman-Smith KB, Costeas P.

Tissue Antigens. 2015 Apr;85(4):267-77. doi: 10.1111/tan.12543.

12.

The EUTOS population-based registry: incidence and clinical characteristics of 2904 CML patients in 20 European Countries.

Hoffmann VS, Baccarani M, Hasford J, Lindoerfer D, Burgstaller S, Sertic D, Costeas P, Mayer J, Indrak K, Everaus H, Koskenvesa P, Guilhot J, Schubert-Fritschle G, Castagnetti F, Di Raimondo F, Lejniece S, Griskevicius L, Thielen N, Sacha T, Hellmann A, Turkina AG, Zaritskey A, Bogdanovic A, Sninska Z, Zupan I, Steegmann JL, Simonsson B, Clark RE, Covelli A, Guidi G, Hehlmann R.

Leukemia. 2015 Jun;29(6):1336-43. doi: 10.1038/leu.2015.73. Epub 2015 Mar 18.

PMID:
25783795
13.

cDNA synthesis for BCR-ABL1 detection at the MMR level: the importance of using the appropriate kit.

Chi J, Pierides C, Mitsidou A, Miltiadou A, Gerasimou P, Costeas P.

Biol Proced Online. 2015 Feb 9;17(1):4. doi: 10.1186/s12575-015-0014-x. eCollection 2015.

14.

Characterization of gene mutations and copy number changes in acute myeloid leukemia using a rapid target enrichment protocol.

Bolli N, Manes N, McKerrell T, Chi J, Park N, Gundem G, Quail MA, Sathiaseelan V, Herman B, Crawley C, Craig JI, Conte N, Grove C, Papaemmanuil E, Campbell PJ, Varela I, Costeas P, Vassiliou GS.

Haematologica. 2015 Feb;100(2):214-22. doi: 10.3324/haematol.2014.113381. Epub 2014 Nov 7.

15.

Calreticulin mutations in myeloproliferative neoplasms and new methodology for their detection and monitoring.

Chi J, Manoloukos M, Pierides C, Nicolaidou V, Nicolaou K, Kleopa M, Vassiliou G, Costeas P.

Ann Hematol. 2015 Mar;94(3):399-408. doi: 10.1007/s00277-014-2232-8. Epub 2014 Oct 29.

PMID:
25349114
16.

Calreticulin gene exon 9 frameshift mutations in patients with thrombocytosis.

Chi J, Nicolaou KA, Nicolaidou V, Koumas L, Mitsidou A, Pierides C, Manoloukos M, Barbouti K, Melanthiou F, Prokopiou C, Vassiliou GS, Costeas P.

Leukemia. 2014 May;28(5):1152-4. doi: 10.1038/leu.2013.382. Epub 2013 Dec 24. No abstract available.

17.

Detailed molecular characterisation of acute myeloid leukaemia with a normal karyotype using targeted DNA capture.

Conte N, Varela I, Grove C, Manes N, Yusa K, Moreno T, Segonds-Pichon A, Bench A, Gudgin E, Herman B, Bolli N, Ellis P, Haddad D, Costeas P, Rad R, Scott M, Huntly B, Bradley A, Vassiliou GS.

Leukemia. 2013 Sep;27(9):1820-5. doi: 10.1038/leu.2013.117. Epub 2013 Apr 18.

18.

Induction of discrete apoptotic pathways by bromo-substituted indirubin derivatives in invasive breast cancer cells.

Nicolaou KA, Liapis V, Evdokiou A, Constantinou C, Magiatis P, Skaltsounis AL, Koumas L, Costeas PA, Constantinou AI.

Biochem Biophys Res Commun. 2012 Aug 17;425(1):76-82. doi: 10.1016/j.bbrc.2012.07.053. Epub 2012 Jul 20.

PMID:
22820195
19.

Homocysteine levels and MTHFR polymorphisms in young patients with acute myocardial infarction: a case control study.

Eftychiou C, Antoniades L, Makri L, Koumas L, Costeas PA, Kyriakou E, Nicolaides E, Papadogiannis D.

Hellenic J Cardiol. 2012 May-Jun;53(3):189-94.

20.

Donors as research subjects: a challenge.

King R, Schmidt AH, Costeas P, Egeland T.

Bone Marrow Transplant. 2012 Apr;47(4):605-6. doi: 10.1038/bmt.2011.127. Epub 2011 Jun 13. No abstract available.

PMID:
21666736
21.

Unrelated hematopoietic stem cell donors as research subjects.

King RJ, Confer DL, Greinix HT, Halter J, Horowitz M, Schmidt AH, Costeas P, Shaw B, Egeland T; Ethics and Clinical Working Groups of World Marrow Donor Association.

Bone Marrow Transplant. 2011 Jan;46(1):10-3. doi: 10.1038/bmt.2010.37. Epub 2010 Mar 1.

PMID:
20190845
22.

Haematopoietic stem cell donor registries: World Marrow Donor Association recommendations for evaluation of donor health.

Sacchi N, Costeas P, Hartwell L, Hurley CK, Raffoux C, Rosenmayr A, Greinix H; Quality Assurance and Clinical Working Groups of the World Marrow Donor Association.

Bone Marrow Transplant. 2008 Jul;42(1):9-14. doi: 10.1038/bmt.2008.76. Epub 2008 Mar 24.

PMID:
18362904
23.

Th2/Th3 cytokine genotypes are associated with pregnancy loss.

Costeas PA, Koumouli A, Giantsiou-Kyriakou A, Papaloizou A, Koumas L.

Hum Immunol. 2004 Feb;65(2):135-41.

PMID:
14969768
24.

Genetic assessment of cardiovascular risk factors in the Greek Cypriot population.

Koumas L, Costeas PA, Papaloizou A, Giantsiou-Kyriakou A.

Thromb Res. 2003;112(3):143-6. No abstract available.

PMID:
14967410
25.

Cytokine polymorphism frequencies in the Greek Cypriot population.

Costeas PA, Koumas L, Koumouli A, Kyriakou-Giantsiou A, Papaloizou A.

Eur J Immunogenet. 2003 Oct;30(5):341-3.

PMID:
14641541
26.

Acidification and glucocorticoids independently regulate branched-chain alpha-ketoacid dehydrogenase subunit genes.

Wang X, Chinsky JM, Costeas PA, Price SR.

Am J Physiol Cell Physiol. 2001 May;280(5):C1176-83.

27.
28.
30.

Isolation of the murine branched-chain alpha-ketoacid dehydrogenase E2 subunit promoter region.

Costeas PA, Chinsky JM.

Biochim Biophys Acta. 1998 Jul 30;1399(1):111-6.

PMID:
9714767
31.

Molecular characterization of a unique patient with epimerase-deficiency galactosaemia.

Alano A, Almashanu S, Chinsky JM, Costeas P, Blitzer MG, Wulfsberg EA, Cowan TM.

J Inherit Metab Dis. 1998 Jun;21(4):341-50.

PMID:
9700591
32.
33.

Molecular cloning of the murine branched chain alpha-ketoacid dehydrogenase E2 subunit: presence of 3' B1 repeat elements.

Costeas PA, Tonelli LA, Chinsky JM.

Biochim Biophys Acta. 1996 Feb 7;1305(1-2):25-8.

PMID:
8605244
34.

Noncoordinated responses of branched-chain alpha-ketoacid dehydrogenase subunit genes to dietary protein.

Chinsky JM, Bohlen LM, Costeas PA.

FASEB J. 1994 Jan;8(1):114-20. Erratum in: FASEB J 1994 Mar 1;8(3):355.

PMID:
7507870
35.

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