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Items: 1 to 50 of 105

1.

Torquetenovirus (TTV) load is associated with mortality in Italian elderly subjects.

Giacconi R, Maggi F, Macera L, Pistello M, Provinciali M, Giannecchini S, Martelli F, Spezia PG, Mariani E, Galeazzi R, Costarelli L, Iovino L, Galimberti S, Nisi L, Piacenza F, Malavolta M.

Exp Gerontol. 2018 Oct 2;112:103-111. doi: 10.1016/j.exger.2018.09.003. Epub 2018 Sep 14.

PMID:
30223047
2.

ZnT8 Arg325Trp polymorphism influences zinc transporter expression and cytokine production in PBMCs from patients with diabetes.

Giacconi R, Malavolta M, Chiodi L, Boccoli G, Costarelli L, Bonfigli AR, Galeazzi R, Piacenza F, Basso A, Gasparini N, Nisi L, Testa R, Provinciali M.

Diabetes Res Clin Pract. 2018 Oct;144:102-110. doi: 10.1016/j.diabres.2018.08.001. Epub 2018 Aug 22.

PMID:
30142362
3.

Zinc supplementation can reduce accumulation of cadmium in aged metallothionein transgenic mice.

Pabis K, Gundacker C, Giacconi R, Basso A, Costarelli L, Piacenza F, Strizzi S, Provinciali M, Malavolta M.

Chemosphere. 2018 Nov;211:855-860. doi: 10.1016/j.chemosphere.2018.08.017. Epub 2018 Aug 4.

PMID:
30103140
4.

Prognostic Significance of Neutrophil-to-lymphocyte Ratio in the Framework of the 8th TNM Edition for Breast Cancer.

Ferroni P, Roselli M, Buonomo OC, Spila A, Portarena I, Laudisi A, Valente MG, Pirillo SP, Fortunato L, Costarelli L, Cavaliere F, Guadagni F.

Anticancer Res. 2018 Aug;38(8):4705-4712. doi: 10.21873/anticanres.12777.

PMID:
30061239
5.

Oxidative Stress in Elderly with Different Cognitive Status: My Mind Project.

Fattoretti P, Malavolta M, Fabbietti P, Papa R, Giacconi R, Costarelli L, Galeazzi R, Paoloni C, Postacchini D, Lattanzio F, Giuli C.

J Alzheimers Dis. 2018;63(4):1405-1414. doi: 10.3233/JAD-171117.

PMID:
29843238
6.

Measuring zinc in biological nanovesicles by multiple analytical approaches.

Piacenza F, Biesemeier A, Farina M, Piva F, Jin X, Pavoni E, Nisi L, Cardelli M, Costarelli L, Giacconi R, Basso A, Pierpaoli E, Provinciali M, Hwang JCM, Morini A, di Donato A, Malavolta M.

J Trace Elem Med Biol. 2018 Jul;48:58-66. doi: 10.1016/j.jtemb.2018.03.010. Epub 2018 Mar 12.

PMID:
29773195
7.

Inducers of Senescence, Toxic Compounds, and Senolytics: The Multiple Faces of Nrf2-Activating Phytochemicals in Cancer Adjuvant Therapy.

Malavolta M, Bracci M, Santarelli L, Sayeed MA, Pierpaoli E, Giacconi R, Costarelli L, Piacenza F, Basso A, Cardelli M, Provinciali M.

Mediators Inflamm. 2018 Feb 12;2018:4159013. doi: 10.1155/2018/4159013. eCollection 2018. Review.

8.

PD-L1 Expression in TNBC: A Predictive Biomarker of Response to Neoadjuvant Chemotherapy?

Cerbelli B, Pernazza A, Botticelli A, Fortunato L, Monti M, Sciattella P, Campagna D, Mazzuca F, Mauri M, Naso G, Marchetti P, d'Amati G, Costarelli L.

Biomed Res Int. 2017;2017:1750925. doi: 10.1155/2017/1750925. Epub 2017 Dec 14.

9.

Pleomorphic lobular carcinoma: is it more similar to a classic lobular cancer or to a high-grade ductal cancer?

Costarelli L, Campagna D, Ascarelli A, Cavaliere F, Colavito MH, Ponzani T, Broglia L, La Pinta M, Manna E, Fortunato L.

Breast Cancer (Dove Med Press). 2017 Dec 8;9:581-586. doi: 10.2147/BCTT.S145570. eCollection 2017.

10.

Zinc-Induced Metallothionein in Centenarian Offspring From a Large European Population: The MARK-AGE Project.

Giacconi R, Costarelli L, Piacenza F, Basso A, Bürkle A, Moreno-Villanueva M, Grune T, Weber D, Stuetz W, Gonos ES, Schön C, Grubeck-Loebenstein B, Sikora E, Toussaint O, Debacq-Chainiaux F, Franceschi C, Hervonen A, Slagboom E, Ciccarone F, Zampieri M, Caiafa P, Jansen E, Dollé MET, Breusing N, Mocchegiani E, Malavolta M.

J Gerontol A Biol Sci Med Sci. 2018 May 9;73(6):745-753. doi: 10.1093/gerona/glx192.

PMID:
29045571
11.

Changes in Zn homeostasis during long term culture of primary endothelial cells and effects of Zn on endothelial cell senescence.

Malavolta M, Costarelli L, Giacconi R, Basso A, Piacenza F, Pierpaoli E, Provinciali M, Ogo OA, Ford D.

Exp Gerontol. 2017 Dec 1;99:35-45. doi: 10.1016/j.exger.2017.09.006. Epub 2017 Sep 14.

PMID:
28918363
12.

Implications of impaired zinc homeostasis in diabetic cardiomyopathy and nephropathy.

Giacconi R, Cai L, Costarelli L, Cardelli M, Malavolta M, Piacenza F, Provinciali M.

Biofactors. 2017 Nov;43(6):770-784. doi: 10.1002/biof.1386. Epub 2017 Aug 27. Review.

PMID:
28845600
13.

Dysfunctional macrophages in Alzheimer Disease: another piece of the "macroph-aging" puzzle?

Costarelli L, Malavolta M, Giacconi R, Provinciali M.

Aging (Albany NY). 2017 Aug 5;9(8):1865-1866. doi: 10.18632/aging.101276. No abstract available.

14.

Different transcriptional profiling between senescent and non-senescent human coronary artery endothelial cells (HCAECs) by Omeprazole and Lansoprazole treatment.

Costarelli L, Giacconi R, Malavolta M, Basso A, Piacenza F, Provinciali M, Maggio MG, Corsonello A, Lattanzio F.

Biogerontology. 2017 Apr;18(2):217-236. doi: 10.1007/s10522-016-9675-3. Epub 2016 Dec 30.

PMID:
28039570
15.

Oxidant stress as a major determinant of platelet activation in invasive breast cancer.

Ferroni P, Santilli F, Cavaliere F, Simeone P, Costarelli L, Liani R, Tripaldi R, Riondino S, Roselli M, Davi G, Guadagni F.

Int J Cancer. 2017 Feb 1;140(3):696-704. doi: 10.1002/ijc.30488. Epub 2016 Nov 7.

16.

Brachyury, a vaccine target, is overexpressed in triple-negative breast cancer.

Hamilton DH, Roselli M, Ferroni P, Costarelli L, Cavaliere F, Taffuri M, Palena C, Guadagni F.

Endocr Relat Cancer. 2016 Oct;23(10):783-796. doi: 10.1530/ERC-16-0037.

17.

Main biomarkers associated with age-related plasma zinc decrease and copper/zinc ratio in healthy elderly from ZincAge study.

Giacconi R, Costarelli L, Piacenza F, Basso A, Rink L, Mariani E, Fulop T, Dedoussis G, Herbein G, Provinciali M, Jajte J, Lengyel I, Mocchegiani E, Malavolta M.

Eur J Nutr. 2017 Dec;56(8):2457-2466. doi: 10.1007/s00394-016-1281-2. Epub 2016 Jul 26.

PMID:
27459881
18.

Functional impairment of activated protein C in breast cancer - relationship to survival outcomes.

Roselli M, Ferroni P, Riondino S, Mariotti S, Portarena I, Alessandroni J, Ialongo C, Massoud R, Costarelli L, Cavaliere F, Bernardini S, Guadagni F.

Am J Cancer Res. 2016 Jun 1;6(6):1450-7. eCollection 2016.

19.

Pretreatment Insulin Levels as a Prognostic Factor for Breast Cancer Progression.

Ferroni P, Riondino S, Laudisi A, Portarena I, Formica V, Alessandroni J, D'Alessandro R, Orlandi A, Costarelli L, Cavaliere F, Guadagni F, Roselli M.

Oncologist. 2016 Sep;21(9):1041-9. doi: 10.1634/theoncologist.2015-0462. Epub 2016 Jul 7.

20.

Once Daily Accelerated Partial Breast Irradiation: Preliminary Results with Helical Tomotherapy®.

DE Paula U, D'Angelillo RM, Barbara R, Caruso C, Gomellini S, Caccavari A, Costarelli L, Scavina P, Mauri M, Santini E, Antonaci A, Cavaliere F, LA Pinta M, Loreti A, Fortunato L.

Anticancer Res. 2016 Jun;36(6):3035-9.

PMID:
27272823
21.

My Mind Project: the effects of cognitive training for elderly-the study protocol of a prospective randomized intervention study.

Giuli C, Fattoretti P, Gagliardi C, Mocchegiani E, Venarucci D, Balietti M, Casoli T, Costarelli L, Giacconi R, Malavolta M, Papa R, Lattanzio F, Postacchini D.

Aging Clin Exp Res. 2017 Jun;29(3):353-360. doi: 10.1007/s40520-016-0570-1. Epub 2016 Apr 22.

22.

Circadian rhythms of body temperature and locomotor activity in aging BALB/c mice: early and late life span predictors.

Basso A, Del Bello G, Piacenza F, Giacconi R, Costarelli L, Malavolta M.

Biogerontology. 2016 Aug;17(4):703-14. doi: 10.1007/s10522-016-9635-y. Epub 2016 Jan 28.

PMID:
26820297
23.

Effect of ZIP2 Gln/Arg/Leu (rs2234632) polymorphism on zinc homeostasis and inflammatory response following zinc supplementation.

Giacconi R, Costarelli L, Malavolta M, Cardelli M, Galeazzi R, Piacenza F, Gasparini N, Basso A, Mariani E, Fulop T, Rink L, Dedoussis G, Herbein G, Jajte J, Provinciali M, Busco F, Mocchegiani E.

Biofactors. 2015 Nov-Dec;41(6):414-23. doi: 10.1002/biof.1247. Epub 2015 Dec 8.

PMID:
26643924
24.

Cellular Senescence and Inflammatory Burden as Determinants of Mortality in Elderly People Until the Extreme old age.

Giacconi R, Malavolta M, Costarelli L, Provinciali M.

EBioMedicine. 2015 Sep 11;2(10):1316-7. doi: 10.1016/j.ebiom.2015.09.015. eCollection 2015 Oct. No abstract available.

25.

Metallothioneins, longevity and cancer: Comment on "Deficiency of metallothionein-1 and -2 genes shortens the lifespan of the 129/Sv mouse strain".

Malavolta M, Orlando F, Piacenza F, Giacconi R, Costarelli L, Basso A, Lucarini G, Pierpaoli E, Provinciali M.

Exp Gerontol. 2016 Jan;73:28-30. doi: 10.1016/j.exger.2015.11.014. Epub 2015 Nov 23. No abstract available.

PMID:
26615880
26.

Neoadjuvant chemotherapy is not a contraindication for nipple sparing mastectomy.

Santoro S, Loreti A, Cavaliere F, Costarelli L, La Pinta M, Manna E, Mauri M, Scavina P, Santini E, De Paula U, Toto V, Fortunato L.

Breast. 2015 Oct;24(5):661-6. doi: 10.1016/j.breast.2015.08.001. Epub 2015 Sep 3.

PMID:
26343944
27.

Pleiotropic Effects of Tocotrienols and Quercetin on Cellular Senescence: Introducing the Perspective of Senolytic Effects of Phytochemicals.

Malavolta M, Pierpaoli E, Giacconi R, Costarelli L, Piacenza F, Basso A, Cardelli M, Provinciali M.

Curr Drug Targets. 2016;17(4):447-59. Review.

PMID:
26343116
28.

Effect of 6-month caloric restriction on Cu bound to ceruloplasmin in adult overweight subjects.

Piacenza F, Malavolta M, Basso A, Costarelli L, Giacconi R, Ravussin E, Redman LM, Mocchegiani E.

J Nutr Biochem. 2015 Aug;26(8):876-82. doi: 10.1016/j.jnutbio.2015.03.012. Epub 2015 May 6.

29.

Serum copper to zinc ratio: Relationship with aging and health status.

Malavolta M, Piacenza F, Basso A, Giacconi R, Costarelli L, Mocchegiani E.

Mech Ageing Dev. 2015 Nov;151:93-100. doi: 10.1016/j.mad.2015.01.004. Epub 2015 Feb 7. Review.

30.

Modulators of cellular senescence: mechanisms, promises, and challenges from in vitro studies with dietary bioactive compounds.

Malavolta M, Costarelli L, Giacconi R, Piacenza F, Basso A, Pierpaoli E, Marchegiani F, Cardelli M, Provinciali M, Mocchegiani E.

Nutr Res. 2014 Dec;34(12):1017-35. doi: 10.1016/j.nutres.2014.02.006. Epub 2014 Mar 6. Review.

PMID:
25476190
31.

Influence of +1245 A/G MT1A polymorphism on advanced glycation end-products (AGEs) in elderly: effect of zinc supplementation.

Giacconi R, Simm A, Santos AN, Costarelli L, Malavolta M, Mecocci P, Piacenza F, Basso A, Fulop T, Rink L, Dedoussis G, Kanoni S, Herbein G, Jajte J, Mocchegiani E.

Genes Nutr. 2014 Sep;9(5):426. doi: 10.1007/s12263-014-0426-2. Epub 2014 Aug 23.

32.

Overexpression of the EMT driver brachyury in breast carcinomas: association with poor prognosis.

Palena C, Roselli M, Litzinger MT, Ferroni P, Costarelli L, Spila A, Cavaliere F, Huang B, Fernando RI, Hamilton DH, Jochems C, Tsang KY, Cheng Q, Lyerly HK, Schlom J, Guadagni F.

J Natl Cancer Inst. 2014 May 9;106(5). pii: dju054. doi: 10.1093/jnci/dju054.

33.

Effects of zinc-fortified drinking skim milk (as functional food) on cytokine release and thymic hormone activity in very old persons: a pilot study.

Costarelli L, Giacconi R, Malavolta M, Basso A, Piacenza F, DeMartiis M, Giannandrea E, Renieri C, Busco F, Galeazzi R, Mocchegiani E.

Age (Dordr). 2014 Jun;36(3):9656. doi: 10.1007/s11357-014-9656-x. Epub 2014 Apr 26.

34.

Plasma plasminogen activator inhibitor-1 (PAI-1) levels in breast cancer - relationship with clinical outcome.

Ferroni P, Roselli M, Portarena I, Formica V, Riondino S, LA Farina F, Costarelli L, Melino A, Massimiani G, Cavaliere F, Palmirotta R, Guadagni F.

Anticancer Res. 2014 Mar;34(3):1153-61.

PMID:
24596353
35.

Vitamin E-gene interactions in aging and inflammatory age-related diseases: implications for treatment. A systematic review.

Mocchegiani E, Costarelli L, Giacconi R, Malavolta M, Basso A, Piacenza F, Ostan R, Cevenini E, Gonos ES, Franceschi C, Monti D.

Ageing Res Rev. 2014 Mar;14:81-101. doi: 10.1016/j.arr.2014.01.001. Epub 2014 Jan 11. Review.

PMID:
24418256
36.

Micronutrient-gene interactions related to inflammatory/immune response and antioxidant activity in ageing and inflammation. A systematic review.

Mocchegiani E, Costarelli L, Giacconi R, Malavolta M, Basso A, Piacenza F, Ostan R, Cevenini E, Gonos ES, Monti D.

Mech Ageing Dev. 2014 Mar-Apr;136-137:29-49. doi: 10.1016/j.mad.2013.12.007. Epub 2014 Jan 2. Review.

PMID:
24388876
37.

Association among 1267 A/G HSP70-2, -308 G/A TNF-α polymorphisms and pro-inflammatory plasma mediators in old ZincAge population.

Giacconi R, Costarelli L, Malavolta M, Piacenza F, Galeazzi R, Gasparini N, Basso A, Mariani E, Fulop T, Rink L, Dedoussis G, Kanoni S, Herbein G, Jajte J, Busco F, Mocchegiani E.

Biogerontology. 2014 Feb;15(1):65-79. doi: 10.1007/s10522-013-9480-1. Epub 2013 Nov 16.

PMID:
24243066
38.

External Quality Assessment (EQA) program for the preanalytical and analytical immunohistochemical determination of HER2 in breast cancer: an experience on a regional scale.

Terrenato I, Arena V, Pizzamiglio S, Pennacchia I, Perracchio L, Buglioni S, Ercolani C, Sperati F, Costarelli L, Bonanno E, Baldini D, Candia S, Crescenzi A, Dal Mas A, Di Cristofano C, Gomes V, Grillo LR, Pasquini P, Pericoli MN, Ramieri MT, Di Stefano D, Ruco L, Scarpino S, Vitolo D, d'Amati G, Paradiso A, Verderio P, Mottolese M.

J Exp Clin Cancer Res. 2013 Aug 21;32:58. doi: 10.1186/1756-9966-32-58.

39.

When mastectomy is needed: is the nipple-sparing procedure a new standard with very few contraindications?

Fortunato L, Loreti A, Andrich R, Costarelli L, Amini M, Farina M, Santini E, Vitelli CE.

J Surg Oncol. 2013 Sep;108(4):207-12. doi: 10.1002/jso.23390. Epub 2013 Aug 1.

PMID:
23913775
40.

Is there a possible single mediator in modulating neuroendocrine-thymus interaction in ageing?

Mocchegiani E, Malavolta M, Costarelli L, Giacconi R, Piacenza F, Lattanzio F, Basso A.

Curr Aging Sci. 2013 Feb;6(1):99-107. Review.

PMID:
23895527
41.

Mutational analysis of gastrointestinal stromal tumors (GISTs): procedural approach for diagnostic purposes.

Palmirotta R, De Marchis ML, Ludovici G, Leone B, Covello R, Conti S, Costarelli L, Della-Morte D, Ferroni P, Roselli M, Guadagni F.

Cancer Genomics Proteomics. 2013 May-Jun;10(3):115-23.

PMID:
23741027
42.

Metallothioneins, ageing and cellular senescence: a future therapeutic target.

Mocchegiani E, Costarelli L, Basso A, Giacconi R, Piacenza F, Malavolta M.

Curr Pharm Des. 2013;19(9):1753-64. Review.

PMID:
23061732
43.

Peripheral mononuclear cell rejuvenation for senescence surveillance in Alzheimer disease.

Malavolta M, Basso A, Piacenza F, Costarelli L, Giacconi R, Mocchegiani E.

Curr Pharm Des. 2013;19(9):1720-6. Review.

PMID:
23061729
44.

Intraductal proliferative lesions of the breast-terminology and biology matter: premalignant lesions or preinvasive cancer?

Costarelli L, Campagna D, Mauri M, Fortunato L.

Int J Surg Oncol. 2012;2012:501904. doi: 10.1155/2012/501904. Epub 2012 May 10.

45.

Brachyury, a driver of the epithelial-mesenchymal transition, is overexpressed in human lung tumors: an opportunity for novel interventions against lung cancer.

Roselli M, Fernando RI, Guadagni F, Spila A, Alessandroni J, Palmirotta R, Costarelli L, Litzinger M, Hamilton D, Huang B, Tucker J, Tsang KY, Schlom J, Palena C.

Clin Cancer Res. 2012 Jul 15;18(14):3868-79. doi: 10.1158/1078-0432.CCR-11-3211. Epub 2012 May 18.

46.

Survival study of metallothionein-1 transgenic mice and respective controls (C57BL/6J): influence of a zinc-enriched environment.

Malavolta M, Basso A, Piacenza F, Giacconi R, Costarelli L, Pierpaoli S, Mocchegiani E.

Rejuvenation Res. 2012 Apr;15(2):140-3. doi: 10.1089/rej.2011.1261.

PMID:
22533418
47.

Micronutrient (Zn, Cu, Fe)-gene interactions in ageing and inflammatory age-related diseases: implications for treatments.

Mocchegiani E, Costarelli L, Giacconi R, Piacenza F, Basso A, Malavolta M.

Ageing Res Rev. 2012 Apr;11(2):297-319. doi: 10.1016/j.arr.2012.01.004. Epub 2012 Jan 31. Review.

PMID:
22322094
48.

Metalloproteases/anti-metalloproteases imbalance in chronic obstructive pulmonary disease: genetic factors and treatment implications.

Mocchegiani E, Giacconi R, Costarelli L.

Curr Opin Pulm Med. 2011 Dec;17 Suppl 1:S11-9. doi: 10.1097/01.mcp.0000410743.98087.12. Review.

PMID:
22209925
49.

Zinc: dietary intake and impact of supplementation on immune function in elderly.

Mocchegiani E, Romeo J, Malavolta M, Costarelli L, Giacconi R, Diaz LE, Marcos A.

Age (Dordr). 2013 Jun;35(3):839-60. doi: 10.1007/s11357-011-9377-3. Epub 2012 Jan 6. Review.

50.

Comparison of intracellular zinc signals in nonadherent lymphocytes from young-adult and elderly donors: role of zinc transporters (Zip family) and proinflammatory cytokines.

Giacconi R, Malavolta M, Costarelli L, Busco F, Galeazzi R, Bernardini G, Gasparini N, Mocchegiani E.

J Nutr Biochem. 2012 Oct;23(10):1256-63. doi: 10.1016/j.jnutbio.2011.07.005. Epub 2011 Dec 29.

PMID:
22209006

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