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Investigating the role of octamer binding transcription Factor-4 (Oct-4) in oral cavity squamous cell carcinoma: A systematic review and meta-analysis.

Gliagias V, Wotman M, Herman SW, Costantino P, Kraus D, Tham T.

Am J Otolaryngol. 2018 Dec 21. pii: S0196-0709(18)31096-2. doi: 10.1016/j.amjoto.2018.12.011. [Epub ahead of print] No abstract available.


On the mechanisms of conjugate vaccines.

Rappuoli R, De Gregorio E, Costantino P.

Proc Natl Acad Sci U S A. 2019 Jan 2;116(1):14-16. doi: 10.1073/pnas.1819612116. Epub 2018 Dec 21. No abstract available.


From A. rhizogenes RolD to Plant P5CS: Exploiting Proline to Control Plant Development.

Trovato M, Mattioli R, Costantino P.

Plants (Basel). 2018 Dec 6;7(4). pii: E108. doi: 10.3390/plants7040108. Review.


Proline synthesis in developing microspores is required for pollen development and fertility.

Mattioli R, Biancucci M, El Shall A, Mosca L, Costantino P, Funck D, Trovato M.

BMC Plant Biol. 2018 Dec 17;18(1):356. doi: 10.1186/s12870-018-1571-3.


Abscisic acid inhibits hypocotyl elongation acting on gibberellins, DELLA proteins and auxin.

Lorrai R, Boccaccini A, Ruta V, Possenti M, Costantino P, Vittorioso P.

AoB Plants. 2018 Oct 5;10(5):ply061. doi: 10.1093/aobpla/ply061. eCollection 2018 Oct.


Genome-wide RNA-seq analysis indicates that the DAG1 transcription factor promotes hypocotyl elongation acting on ABA, ethylene and auxin signaling.

Lorrai R, Gandolfi F, Boccaccini A, Ruta V, Possenti M, Tramontano A, Costantino P, Lepore R, Vittorioso P.

Sci Rep. 2018 Oct 26;8(1):15895. doi: 10.1038/s41598-018-34256-3.


Efficacy of a non-invasive middle ear aeration device in children with recurrent otitis media: A randomized controlled trial protocol.

Tham T, Rahman L, Costantino P.

Contemp Clin Trials Commun. 2018 Oct 4;12:92-97. doi: 10.1016/j.conctc.2018.09.008. eCollection 2018 Dec.


Analysis of bone healing with a novel bone wax substitute compared with bone wax in a porcine bone defect model.

Tham T, Roberts K, Shanahan J, Burban J, Costantino P.

Future Sci OA. 2018 Jul 26;4(8):FSO326. doi: 10.4155/fsoa-2018-0004. eCollection 2018 Sep.


Evaluation of the prognostic utility of the hemoglobin-to-red cell distribution width ratio in head and neck cancer.

Tham T, Olson C, Wotman M, Teegala S, Khaymovich J, Coury J, Costantino P.

Eur Arch Otorhinolaryngol. 2018 Nov;275(11):2869-2878. doi: 10.1007/s00405-018-5144-8. Epub 2018 Sep 24.


SCARECROW and SHORTROOT control the auxin/cytokinin balance necessary for embryonic stem cell niche specification.

Salvi E, Di Mambro R, Pacifici E, Dello Ioio R, Costantino P, Moubayidin L, Sabatini S.

Plant Signal Behav. 2018;13(8):e1507402. doi: 10.1080/15592324.2018.1507402. Epub 2018 Aug 20.


Is human papillomavirus and p16 expression associated with survival outcomes in nasopharyngeal cancer?: A systematic review and meta-analysis.

Tham T, Teegala S, Bardash Y, Herman SW, Costantino P.

Am J Otolaryngol. 2018 Nov - Dec;39(6):764-770. doi: 10.1016/j.amjoto.2018.07.005. Epub 2018 Jul 11. Review.


Acidic cell elongation drives cell differentiation in the Arabidopsis root.

Pacifici E, Di Mambro R, Dello Ioio R, Costantino P, Sabatini S.

EMBO J. 2018 Aug 15;37(16). pii: e99134. doi: 10.15252/embj.201899134. Epub 2018 Jul 16.


An auxin switch for male fertility.

Cardarelli M, Costantino P.

Nat Plants. 2018 Jul;4(7):408-409. doi: 10.1038/s41477-018-0200-3. No abstract available.


Protein Carriers for Glycoconjugate Vaccines: History, Selection Criteria, Characterization and New Trends.

Micoli F, Adamo R, Costantino P.

Molecules. 2018 Jun 15;23(6). pii: E1451. doi: 10.3390/molecules23061451. Review.


Neutrophil-to-lymphocyte ratio as a prognostic indicator in head and neck cancer: A systematic review and meta-analysis.

Tham T, Bardash Y, Herman SW, Costantino PD.

Head Neck. 2018 Nov;40(11):2546-2557. doi: 10.1002/hed.25324. Epub 2018 May 14. Review.


The red cell distribution width as a prognostic indicator in upper aerodigestive tract (UADT) cancer: A systematic review and meta-analysis.

Tham T, Bardash Y, Teegala S, Herman WS, Costantino PD.

Am J Otolaryngol. 2018 Jul - Aug;39(4):453-458. doi: 10.1016/j.amjoto.2018.04.013. Epub 2018 Apr 21. Review.


The lymphocyte-to-monocyte ratio as a prognostic indicator in head and neck cancer: a systematic review and meta-analysis.

Tham T, Olson C, Khaymovich J, Herman SW, Costantino PD.

Eur Arch Otorhinolaryngol. 2018 Jul;275(7):1663-1670. doi: 10.1007/s00405-018-4972-x. Epub 2018 Apr 13. Review.


Neuroradiological and Neuropathological Changes After 177Lu-Octreotate Peptide Receptor Radionuclide Therapy of Refractory Esthesioneuroblastoma.

Schneider JR, Shatzkes DR, Scharf SC, Tham TM, Kulason KO, Buteau FA, Del Prete M, Chakraborty S, Anderson TA, Asiry S, Beauregard JM, Langer DJ, Costantino PD, Boockvar JA.

Oper Neurosurg (Hagerstown). 2018 Dec 1;15(6):100-109. doi: 10.1093/ons/opy028.


Potential targets for next generation antimicrobial glycoconjugate vaccines.

Micoli F, Costantino P, Adamo R.

FEMS Microbiol Rev. 2018 May 1;42(3):388-423. doi: 10.1093/femsre/fuy011. Review.


A Newly Identified Flower-Specific Splice Variant of AUXIN RESPONSE FACTOR8 Regulates Stamen Elongation and Endothecium Lignification in Arabidopsis.

Ghelli R, Brunetti P, Napoli N, De Paolis A, Cecchetti V, Tsuge T, Serino G, Matsui M, Mele G, Rinaldi G, Palumbo GA, Barozzi F, Costantino P, Cardarelli M.

Plant Cell. 2018 Mar;30(3):620-637. doi: 10.1105/tpc.17.00840. Epub 2018 Mar 7.


Venous Thromboembolism Risk in Head and Neck Cancer: Significance of the Preoperative Platelet-to-Lymphocyte Ratio.

Tham T, Rahman L, Persaud C, Olson C, Costantino P.

Otolaryngol Head Neck Surg. 2018 Jul;159(1):85-91. doi: 10.1177/0194599818756851. Epub 2018 Feb 6.


An efficient cell free enzyme-based total synthesis of a meningococcal vaccine candidate.

Fiebig T, Romano MR, Oldrini D, Adamo R, Tontini M, Brogioni B, Santini L, Berger M, Costantino P, Berti F, Gerardy-Schahn R.

NPJ Vaccines. 2016 Nov 15;1:16017. doi: 10.1038/npjvaccines.2016.17. eCollection 2016.


Differential spatial distribution of miR165/6 determines variability in plant root anatomy.

Di Ruocco G, Bertolotti G, Pacifici E, Polverari L, Tsiantis M, Sabatini S, Costantino P, Dello Ioio R.

Development. 2018 Jan 9;145(1). pii: dev153858. doi: 10.1242/dev.153858.


Suprasellar and third ventricular cavernous malformation: Lessons learned in differential diagnosis and surgical planning.

Kulason KO, Schneider JR, Rahme R, Ratzon F, Anderson TA, Shatzkes DR, Filippi CG, Costantino PD, Langer DJ, Boockvar JA.

Surg Neurol Int. 2017 Oct 13;8:251. doi: 10.4103/sni.sni_229_17. eCollection 2017.


Auxin minimum triggers the developmental switch from cell division to cell differentiation in the Arabidopsis root.

Di Mambro R, De Ruvo M, Pacifici E, Salvi E, Sozzani R, Benfey PN, Busch W, Novak O, Ljung K, Di Paola L, Marée AFM, Costantino P, Grieneisen VA, Sabatini S.

Proc Natl Acad Sci U S A. 2017 Sep 5;114(36):E7641-E7649. doi: 10.1073/pnas.1705833114. Epub 2017 Aug 22.


Human leukocyte antigen allele linkage disequilibrium and haplotype structure in volunteer bone marrow donors of Paraná State.

Costantino PR, Zeck SC, da Silva WA, Bicalho MDG.

Rev Bras Hematol Hemoter. 2017 Jul - Sep;39(3):229-236. doi: 10.1016/j.bjhh.2017.01.006. Epub 2017 Feb 21.


The Temporalis Muscle Flap for Palate Reconstruction: Case Series and Review of the Literature.

Brennan T, Tham TM, Costantino P.

Int Arch Otorhinolaryngol. 2017 Jul;21(3):259-264. doi: 10.1055/s-0037-1598653. Epub 2017 Feb 17.


Corrigendum to "Preclinical studies on new proteins as carrier for glycoconjugate vaccines" [Vaccine 34 (2016) 4235-4242].

Tontini M, Romano MR, Proietti D, Balducci E, Micoli F, Balocchi C, Santini L, Masignani V, Berti F, Costantino P.

Vaccine. 2017 May 2;35(19):2612. doi: 10.1016/j.vaccine.2017.03.011. Epub 2017 Mar 30. No abstract available.


Erratum: The Laparoscopically Harvested Omental Free Flap: A Compelling Option for Craniofacial and Cranial Base Reconstruction.

Costantino PD, Shamouelian D, Tham T, Andrews R, Dec W.

J Neurol Surg B Skull Base. 2017 Apr;78(2):e5. doi: 10.1055/s-0037-1604035. Epub 2017 Jul 12.


The Laparoscopically Harvested Omental Free Flap: A Compelling Option for Craniofacial and Cranial Base Reconstruction.

Costantino PD, Shamouelian D, Tham T, Andrews R, Dec W.

J Neurol Surg B Skull Base. 2017 Apr;78(2):191-196. doi: 10.1055/s-0036-1597138. Epub 2016 Dec 7. Erratum in: J Neurol Surg B Skull Base. 2017 Apr;78(2):e5.


Frameless and Maskless Stereotactic Navigation with a Skull-Mounted Tracker.

Fanous AA, White TG, Hirsch MB, Chakraborty S, Costantino PD, Langer DJ, Boockvar JA.

World Neurosurg. 2017 Jun;102:661-667. doi: 10.1016/j.wneu.2017.03.007. Epub 2017 Mar 12.


Mammary Gland Pathology Subsequent to Acute Infection with Strong versus Weak Biofilm Forming Staphylococcus aureus Bovine Mastitis Isolates: A Pilot Study Using Non-Invasive Mouse Mastitis Model.

Gogoi-Tiwari J, Williams V, Waryah CB, Costantino P, Al-Salami H, Mathavan S, Wells K, Tiwari HK, Hegde N, Isloor S, Al-Sallami H, Mukkur T.

PLoS One. 2017 Jan 27;12(1):e0170668. doi: 10.1371/journal.pone.0170668. eCollection 2017.


Intra-arterial cetuximab for the treatment of recurrent unresectable head and neck squamous cell carcinoma.

Tham T, White TG, Chakraborty S, Lall RR, Ortiz R, Langer DJ, Shatzkes D, Filippi CG, Kraus D, Boockvar JA, Costantino PD.

J Exp Ther Oncol. 2016 Nov;11(4):293-301.


In Vitro Antimicrobial Efficacy of Tobramycin Against Staphylococcus aureus Biofilms in Combination With or Without DNase I and/or Dispersin B: A Preliminary Investigation.

Waryah CB, Wells K, Ulluwishewa D, Chen-Tan N, Gogoi-Tiwari J, Ravensdale J, Costantino P, Gökçen A, Vilcinskas A, Wiesner J, Mukkur T.

Microb Drug Resist. 2017 Apr;23(3):384-390. doi: 10.1089/mdr.2016.0100. Epub 2016 Oct 18.


An auxin maximum in the middle layer controls stamen development and pollen maturation in Arabidopsis.

Cecchetti V, Celebrin D, Napoli N, Ghelli R, Brunetti P, Costantino P, Cardarelli M.

New Phytol. 2017 Feb;213(3):1194-1207. doi: 10.1111/nph.14207. Epub 2016 Sep 23.


The DAG1 transcription factor negatively regulates the seed-to-seedling transition in Arabidopsis acting on ABA and GA levels.

Boccaccini A, Lorrai R, Ruta V, Frey A, Mercey-Boutet S, Marion-Poll A, Tarkowská D, Strnad M, Costantino P, Vittorioso P.

BMC Plant Biol. 2016 Sep 9;16(1):198. doi: 10.1186/s12870-016-0890-5.


Preclinical studies on new proteins as carrier for glycoconjugate vaccines.

Tontini M, Romano MR, Proietti D, Balducci E, Micoli F, Balocchi C, Santini L, Masignani V, Berti F, Costantino P.

Vaccine. 2016 Jul 29;34(35):4235-4242. doi: 10.1016/j.vaccine.2016.06.039. Epub 2016 Jun 24. Erratum in: Vaccine. 2017 May 2;35(19):2612.


Exploring host-pathogen interactions through genome wide protein microarray analysis.

Scietti L, Sampieri K, Pinzuti I, Bartolini E, Benucci B, Liguori A, Haag AF, Lo Surdo P, Pansegrau W, Nardi-Dei V, Santini L, Arora S, Leber X, Rindi S, Savino S, Costantino P, Maione D, Merola M, Speziale P, Bottomley MJ, Bagnoli F, Masignani V, Pizza M, Scharenberg M, Schlaeppi JM, Nissum M, Liberatori S.

Sci Rep. 2016 Jun 15;6:27996. doi: 10.1038/srep27996.


Diversity of Virulence Factors Associated with West Australian Methicillin-Sensitive Staphylococcus aureus Isolates of Human Origin.

Waryah CB, Gogoi-Tiwari J, Wells K, Eto KY, Masoumi E, Costantino P, Kotiw M, Mukkur T.

Biomed Res Int. 2016;2016:8651918. doi: 10.1155/2016/8651918. Epub 2016 May 9.


Forearm Cephalic Vein Graft for Short, "Middle"-Flow, Internal Maxillary Artery to Middle Cerebral Artery Bypass.

Nossek E, Costantino PD, Chalif DJ, Ortiz RA, Dehdashti AR, Langer DJ.

Oper Neurosurg (Hagerstown). 2016 Jun 1;12(2):99-105. doi: 10.1227/NEU.0000000000001027.


Factors contributing to the immunogenicity of meningococcal conjugate vaccines.

Bröker M, Berti F, Costantino P.

Hum Vaccin Immunother. 2016 Jul 2;12(7):1808-24. doi: 10.1080/21645515.2016.1153206. Epub 2016 Mar 2. Review.


Expression of factor H binding protein in meningococcal strains can vary at least 15-fold and is genetically determined.

Biagini M, Spinsanti M, De Angelis G, Tomei S, Ferlenghi I, Scarselli M, Rigat F, Messuti N, Biolchi A, Muzzi A, Anderloni G, Brunelli B, Cartocci E, Buricchi F, Tani C, Stella M, Moschioni M, Del Tordello E, Colaprico A, Savino S, Giuliani MM, Delany I, Pizza M, Costantino P, Norais N, Rappuoli R, Masignani V.

Proc Natl Acad Sci U S A. 2016 Mar 8;113(10):2714-9. doi: 10.1073/pnas.1521142113. Epub 2016 Feb 17.


Intramammary Immunization of Pregnant Mice with Staphylococcal Protein A Reduces the Post-Challenge Mammary Gland Bacterial Load but Not Pathology.

Gogoi-Tiwari J, Williams V, Waryah CB, Mathavan S, Tiwari HK, Costantino P, Mukkur T.

PLoS One. 2016 Feb 10;11(2):e0148383. doi: 10.1371/journal.pone.0148383. eCollection 2016.


A SCARECROW-based regulatory circuit controls Arabidopsis thaliana meristem size from the root endodermis.

Moubayidin L, Salvi E, Giustini L, Terpstra I, Heidstra R, Costantino P, Sabatini S.

Planta. 2016 May;243(5):1159-68. doi: 10.1007/s00425-016-2471-0. Epub 2016 Feb 5.


The role of structural proteomics in vaccine development: recent advances and future prospects.

Donnarumma D, Faleri A, Costantino P, Rappuoli R, Norais N.

Expert Rev Proteomics. 2016;13(1):55-68. doi: 10.1586/14789450.2016.1121113. Review.


Multiportal Combined Transorbital and Transnasal Endoscopic Resection of Fibrous Dysplasia.

Tham T, Costantino P, Bruni M, Langer D, Boockvar J, Singh P.

J Neurol Surg Rep. 2015 Nov;76(2):e291-6. doi: 10.1055/s-0035-1566126. Epub 2015 Oct 25.


Probable Immunoglobulin Subtype-G4-Related Disease in the Head and Neck from Foreign Body Injection: A Case Report.

Highstein MJ, Mallen J, Tham T, Brennan T, Boubour A, Opher E, Wolf V, Singh P, Costantino P.

J Neurol Surg Rep. 2015 Nov;76(2):e265-9. doi: 10.1055/s-0035-1564602. Epub 2015 Oct 9.


Proline affects the size of the root meristematic zone in Arabidopsis.

Biancucci M, Mattioli R, Moubayidin L, Sabatini S, Costantino P, Trovato M.

BMC Plant Biol. 2015 Oct 29;15:263. doi: 10.1186/s12870-015-0637-8.


Role of proline and GABA in sexual reproduction of angiosperms.

Biancucci M, Mattioli R, Forlani G, Funck D, Costantino P, Trovato M.

Front Plant Sci. 2015 Sep 4;6:680. doi: 10.3389/fpls.2015.00680. eCollection 2015. Review.


Comparative studies of the immunogenicity and protective potential of biofilm vs planktonic Staphylococcus aureus vaccine against bovine mastitis using non-invasive mouse mastitis as a model system.

Gogoi-Tiwari J, Williams V, Waryah CB, Eto KY, Tau M, Costantino P, Tiwari HK, Mukkur T.

Biofouling. 2015;31(7):543-54. doi: 10.1080/08927014.2015.1074681.


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