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Items: 25


Oncostatin M induces RIG-I and MDA5 expression and enhances the double-stranded RNA response in fibroblasts.

Hergovits S, Mais C, Haan C, Costa-Pereira AP, Hermanns HM.

J Cell Mol Med. 2017 Nov;21(11):3087-3099. doi: 10.1111/jcmm.13221. Epub 2017 May 30.


Phosphorylation of Janus kinase 1 (JAK1) by AMP-activated protein kinase (AMPK) links energy sensing to anti-inflammatory signaling.

Rutherford C, Speirs C, Williams JJ, Ewart MA, Mancini SJ, Hawley SA, Delles C, Viollet B, Costa-Pereira AP, Baillie GS, Salt IP, Palmer TM.

Sci Signal. 2016 Nov 8;9(453):ra109.


DAPK2 regulates oxidative stress in cancer cells by preserving mitochondrial function.

Schlegel CR, Georgiou ML, Misterek MB, Stöcker S, Chater ER, Munro CE, Pardo OE, Seckl MJ, Costa-Pereira AP.

Cell Death Dis. 2015 Mar 5;6:e1671. doi: 10.1038/cddis.2015.31.


DAPK2 is a novel modulator of TRAIL-induced apoptosis.

Schlegel CR, Fonseca AV, Stöcker S, Georgiou ML, Misterek MB, Munro CE, Carmo CR, Seckl MJ, Costa-Pereira AP.

Cell Death Differ. 2014 Nov;21(11):1780-91. doi: 10.1038/cdd.2014.93. Epub 2014 Jul 11.


Regulation of IL-6-type cytokine responses by MAPKs.

Costa-Pereira AP.

Biochem Soc Trans. 2014 Feb;42(1):59-62. doi: 10.1042/BST20130267.


Control of gp130 expression by the mitogen-activated protein kinase ERK2.

Bonito NA, Drechsler J, Stoecker S, Carmo CR, Seckl MJ, Hermanns HM, Costa-Pereira AP.

Oncogene. 2014 Apr 24;33(17):2255-63. doi: 10.1038/onc.2013.159. Epub 2013 May 20.


Dysregulation of janus kinases and signal transducers and activators of transcription in cancer.

Costa-Pereira AP, Bonito NA, Seckl MJ.

Am J Cancer Res. 2011;1(6):806-16. Epub 2011 Jun 22.


A novel requirement for Janus kinases as mediators of drug resistance induced by fibroblast growth factor-2 in human cancer cells.

Carmo CR, Lyons-Lewis J, Seckl MJ, Costa-Pereira AP.

PLoS One. 2011;6(5):e19861. doi: 10.1371/journal.pone.0019861. Epub 2011 May 20.


Signal transducers and activators of transcription-from cytokine signalling to cancer biology.

Santos CI, Costa-Pereira AP.

Biochim Biophys Acta. 2011 Aug;1816(1):38-49. doi: 10.1016/j.bbcan.2011.03.003. Epub 2011 Apr 5. Review.


Distinct clinical phenotypes associated with JAK2V617F reflect differential STAT1 signaling.

Chen E, Beer PA, Godfrey AL, Ortmann CA, Li J, Costa-Pereira AP, Ingle CE, Dermitzakis ET, Campbell PJ, Green AR.

Cancer Cell. 2010 Nov 16;18(5):524-35. doi: 10.1016/j.ccr.2010.10.013.


Multiple kinases in the interferon-gamma response.

Watling D, Carmo CR, Kerr IM, Costa-Pereira AP.

Proc Natl Acad Sci U S A. 2008 Apr 22;105(16):6051-6. doi: 10.1073/pnas.0710814105. Epub 2008 Apr 15.


P-STAT1 mediates higher-order chromatin remodelling of the human MHC in response to IFNgamma.

Christova R, Jones T, Wu PJ, Bolzer A, Costa-Pereira AP, Watling D, Kerr IM, Sheer D.

J Cell Sci. 2007 Sep 15;120(Pt 18):3262-70. Epub 2007 Aug 28.


Signaling through a mutant IFN-gamma receptor.

Costa-Pereira AP, Hermanns HM, Is'harc H, Williams TM, Watling D, Arulampalam V, Newman SJ, Heinrich PC, Kerr IM.

J Immunol. 2005 Nov 1;175(9):5958-65.


Role of tyrosine 441 of interferon-gamma receptor subunit 1 in SOCS-1-mediated attenuation of STAT1 activation.

Qing Y, Costa-Pereira AP, Watling D, Stark GR.

J Biol Chem. 2005 Jan 21;280(3):1849-53. Epub 2004 Nov 1.


Of JAKs, STATs, blind watchmakers, jeeps and trains.

Kerr IM, Costa-Pereira AP, Lillemeier BF, Strobl B.

FEBS Lett. 2003 Jul 3;546(1):1-5. Review.


Molecular and cellular biology of prostate cancer-the role of apoptosis as a target for therapy.

Costa-Pereira AP, Cotter TG.

Prostate Cancer Prostatic Dis. 1999 May;2(3):126-139.


Cell-type and donor-specific transcriptional responses to interferon-alpha. Use of customized gene arrays.

Schlaak JF, Hilkens CM, Costa-Pereira AP, Strobl B, Aberger F, Frischauf AM, Kerr IM.

J Biol Chem. 2002 Dec 20;277(51):49428-37. Epub 2002 Oct 16.


The antiviral response to gamma interferon.

Costa-Pereira AP, Williams TM, Strobl B, Watling D, Briscoe J, Kerr IM.

J Virol. 2002 Sep;76(18):9060-8.


Mutational switch of an IL-6 response to an interferon-gamma-like response.

Costa-Pereira AP, Tininini S, Strobl B, Alonzi T, Schlaak JF, Is'harc H, Gesualdo I, Newman SJ, Kerr IM, Poli V.

Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):8043-7.


A completely foreign receptor can mediate an interferon-gamma-like response.

Strobl B, Arulampalam V, Is'harc H, Newman SJ, Schlaak JF, Watling D, Costa-Pereira AP, Schaper F, Behrmann I, Sheehan KC, Schreiber RD, Horn F, Heinrich PC, Kerr IM.

EMBO J. 2001 Oct 1;20(19):5431-42.


Analysis of gene expression using high-density and IFN-gamma-specific low-density cDNA arrays.

Aberger F, Costa-Pereira AP, Schlaak JF, Williams TM, O'Shaughnessy RF, Hollaus G, Kerr IM, Frischauf AM.

Genomics. 2001 Sep;77(1-2):50-7.


Detection of molecular events during apoptosis by flow cytometry.

Carmody RJ, Costa-Pereira AP, McKenna SL, Cotter TG.

Methods Mol Med. 2000;38:71-83. doi: 10.1385/1-59259-070-5:71.


Chemotherapeutic drug-induced apoptosis in human leukaemic cells is independent of the Fas (APO-1/CD95) receptor/ligand system.

McGahon AJ, Costa Pereira AP, Daly L, Cotter TG.

Br J Haematol. 1998 Jun;101(3):539-47.


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