Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 117

1.

Application of 1,3-Dipolar Reactions between Azomethine Ylides and Alkenes to the Synthesis of Catalysts and Biologically Active Compounds.

Arrastia I, Arrieta A, Cossío FP.

European J Org Chem. 2018 Nov 25;2018(43):5889-5904. doi: 10.1002/ejoc.201800911. Epub 2018 Oct 3. Review.

2.

Alkaloids Reactivity: DFT Analysis of Selective Demethylation Reactions.

Larrañaga O, Miranda JI, Cossio FP, de Cozar A.

J Org Chem. 2018 Nov 20. doi: 10.1021/acs.joc.8b02364. [Epub ahead of print]

PMID:
30457861
3.

1,3-Dioxa-[3,3]-Sigmatropic Oxo-Rearrangement of Substituted Allylic Carbamates: Scope and Mechanistic Studies.

Agirre M, Henrion S, Rivilla I, Miranda JI, Cossio FP, Carboni B, Villalgordo JM, Carreaux F.

J Org Chem. 2018 Nov 20. doi: 10.1021/acs.joc.8b01320. [Epub ahead of print]

PMID:
30457341
4.

Chirality-Induced Electron Spin Polarization and Enantiospecific Response in Solid-State Cross-Polarization Nuclear Magnetic Resonance.

Santos JI, Rivilla I, Cossío FP, Matxain JM, Grzelczak M, Mazinani SKS, Ugalde JM, Mujica V.

ACS Nano. 2018 Nov 27;12(11):11426-11433. doi: 10.1021/acsnano.8b06467. Epub 2018 Nov 13.

PMID:
30407788
5.

Organocatalysts Derived from Unnatural α-Amino Acids: Scope and Applications.

Agirre M, Arrieta A, Arrastia I, Cossío FP.

Chem Asian J. 2019 Jan 4;14(1):44-66. doi: 10.1002/asia.201801296. Epub 2018 Nov 27. Review.

PMID:
30300971
6.

In vitro and in vivo activity of a new small-molecule inhibitor of HDAC6 in mantle cell lymphoma.

Pérez-Salvia M, Aldaba E, Vara Y, Fabre M, Ferrer C, Masdeu C, Zubia A, Sebastian ES, Otaegui D, Llinàs-Arias P, Rosselló-Tortella M, Berdasco M, Moutinho C, Setien F, Villanueva A, González-Barca E, Muncunill J, Navarro JT, Piris MA, Cossio FP, Esteller M.

Haematologica. 2018 Nov;103(11):e537-e540. doi: 10.3324/haematol.2018.189241. Epub 2018 Jun 7. No abstract available.

7.

Synthesis of exo-Imidazolidin-2-one Dienes, Their Isomerization, and Selectivity in Diels-Alder Cycloadditions.

Espinoza-Hicks C, Montoya P, Bautista R, Jiménez-Vázquez HA, Rodríguez-Valdez LM, Camacho-Dávila AA, Cossío FP, Delgado F, Tamariz J.

J Org Chem. 2018 May 18;83(10):5347-5364. doi: 10.1021/acs.joc.7b02344. Epub 2018 Apr 26.

PMID:
29697257
8.

Negishi coupling reactions with [11C]CH3I: a versatile method for efficient 11C-C bond formation.

Rejc L, Gómez-Vallejo V, Alcázar J, Alonso N, Andrés JI, Arrieta A, Cossío FP, Llop J.

Chem Commun (Camb). 2018 Apr 26;54(35):4398-4401. doi: 10.1039/c8cc01540f.

PMID:
29664097
9.

Cooperative Catalysis with Coupled Chiral Induction in 1,3-Dipolar Cycloadditions of Azomethine Ylides.

Cayuelas A, Larrañaga O, Selva V, Nájera C, Akiyama T, Sansano JM, de Cózar A, Miranda JI, Cossío FP.

Chemistry. 2018 Jun 7;24(32):8092-8097. doi: 10.1002/chem.201801433. Epub 2018 May 15.

PMID:
29600546
10.

Density Functional Theory Study on the Demethylation Reaction between Methylamine, Dimethylamine, Trimethylamine, and Tamoxifen Catalyzed by a Fe(IV)-Oxo Porphyrin Complex.

Alberro N, Torrent-Sucarrat M, Arrieta A, Rubiales G, Cossío FP.

J Phys Chem A. 2018 Feb 15;122(6):1658-1671. doi: 10.1021/acs.jpca.7b10654. Epub 2018 Feb 2.

PMID:
29320849
11.

Catalysis of a 1,3-dipolar reaction by distorted DNA incorporating a heterobimetallic platinum(ii) and copper(ii) complex.

Rivilla I, de Cózar A, Schäfer T, Hernandez FJ, Bittner AM, Eleta-Lopez A, Aboudzadeh A, Santos JI, Miranda JI, Cossío FP.

Chem Sci. 2017 Oct 1;8(10):7038-7046. doi: 10.1039/c7sc02311a. Epub 2017 Aug 22.

12.

A Three-Component Enantioselective Cyclization Reaction Catalyzed by an Unnatural Amino Acid Derivative.

de Gracia Retamosa M, Ruiz-Olalla A, Bello T, de Cózar A, Cossío FP.

Angew Chem Int Ed Engl. 2018 Jan 15;57(3):668-672. doi: 10.1002/anie.201708952. Epub 2017 Dec 12.

PMID:
29120526
13.

Mono- and Di-Alkylation Processes of DNA Bases by Nitrogen Mustard Mechlorethamine.

Larrañaga O, de Cózar A, Cossío FP.

Chemphyschem. 2017 Dec 6;18(23):3390-3401. doi: 10.1002/cphc.201700937. Epub 2017 Oct 27.

PMID:
28981213
14.

Relevance of the DFT method to study expanded porphyrins with different topologies.

Torrent-Sucarrat M, Navarro S, Cossío FP, Anglada JM, Luis JM.

J Comput Chem. 2017 Dec 15;38(32):2819-2828. doi: 10.1002/jcc.25074. Epub 2017 Sep 30.

PMID:
28963854
15.

Stereoselective Coupling of N-tert-Butanesulfinyl Aldimines and β-Keto Acids: Access to β-Amino Ketones.

Lahosa A, Soler T, Arrieta A, Cossío FP, Foubelo F, Yus M.

J Org Chem. 2017 Jul 21;82(14):7481-7491. doi: 10.1021/acs.joc.7b01178. Epub 2017 Jul 11.

PMID:
28661149
16.

Enantioselective Ring-Opening Polymerization of rac-Lactide Dictated by Densely Substituted Amino Acids.

Sanchez-Sanchez A, Rivilla I, Agirre M, Basterretxea A, Etxeberria A, Veloso A, Sardon H, Mecerreyes D, Cossío FP.

J Am Chem Soc. 2017 Apr 5;139(13):4805-4814. doi: 10.1021/jacs.6b13080. Epub 2017 Mar 22.

PMID:
28272877
17.

Alkenyl Arenes as Dipolarophiles in Catalytic Asymmetric 1,3-Dipolar Cycloaddition Reactions of Azomethine Ylides.

Pascual-Escudero A, de Cózar A, Cossío FP, Adrio J, Carretero JC.

Angew Chem Int Ed Engl. 2016 Dec 5;55(49):15334-15338. doi: 10.1002/anie.201609187. Epub 2016 Nov 11.

PMID:
27862800
18.

Donor-Stabilized 1,3-Disila-2,4-diazacyclobutadiene with a Nonbonded Si⋅⋅⋅Si Distance Compressed to a Si=Si Double Bond Length.

Gau D, Nougué R, Saffon-Merceron N, Baceiredo A, De Cózar A, Cossío FP, Hashizume D, Kato T.

Angew Chem Int Ed Engl. 2016 Nov 14;55(47):14673-14677. doi: 10.1002/anie.201608416. Epub 2016 Oct 20.

PMID:
27763730
19.

Two-State Reactivity of Histone Demethylases Containing Jumonji-C Active Sites: Different Mechanisms for Different Methylation Degrees.

Alberro N, Torrent-Sucarrat M, Arrastia I, Arrieta A, Cossío FP.

Chemistry. 2017 Jan 1;23(1):137-148. doi: 10.1002/chem.201604219. Epub 2016 Nov 23.

PMID:
27727500
20.

New Insights into the Reactivity of Cisplatin with Free and Restrained Nucleophiles: Microsolvation Effects and Base Selectivity in Cisplatin-DNA Interactions.

de Cózar A, Larrañaga O, Bickelhaupt FM, San Sebastián E, Ortega-Carrasco E, Maréchal JD, Lledós A, Cossío FP.

Chemphyschem. 2016 Dec 5;17(23):3932-3947. doi: 10.1002/cphc.201600982. Epub 2016 Oct 5.

PMID:
27642713
21.

Enantioselective Synthesis of Polysubstituted Spiro-nitroprolinates Mediated by a (R,R)-Me-DuPhos·AgF-Catalyzed 1,3-Dipolar Cycloaddition.

Cayuelas A, Ortiz R, Nájera C, Sansano JM, Larrañaga O, de Cózar A, Cossío FP.

Org Lett. 2016 Jun 17;18(12):2926-9. doi: 10.1021/acs.orglett.6b01273. Epub 2016 Jun 8.

PMID:
27268161
22.

Stereospecific Synthesis of α-Amino Allylsilane Derivatives through a [3,3]-Allyl Cyanate Rearrangement. Mild Formation of Functionalized Disiloxanes.

Henrion S, Carboni B, Cossío FP, Roisnel T, Villalgordo JM, Carreaux F.

J Org Chem. 2016 Jun 3;81(11):4633-44. doi: 10.1021/acs.joc.6b00505. Epub 2016 May 18.

PMID:
27163288
23.

Interplay between aromaticity and strain in double group transfer reactions to 1,2-benzyne.

Fernández I, Cossío FP.

J Comput Chem. 2016 May 30;37(14):1265-73. doi: 10.1002/jcc.24317. Epub 2016 Feb 11.

PMID:
26864872
24.

Microwave-Assisted Organocatalyzed Rearrangement of Propargyl Vinyl Ethers to Salicylaldehyde Derivatives: An Experimental and Theoretical Study.

Tejedor D, Cotos L, Márquez-Arce D, Odriozola-Gimeno M, Torrent-Sucarrat M, Cossío FP, García-Tellado F.

Chemistry. 2015 Dec 7;21(50):18280-9. doi: 10.1002/chem.201503171. Epub 2015 Oct 30.

PMID:
26515241
25.

Enantiodivergent Synthesis of Bis-Spiropyrrolidines via Sequential Interrupted and Completed (3 + 2) Cycloadditions.

Conde E, Rivilla I, Larumbe A, Cossío FP.

J Org Chem. 2015 Dec 4;80(23):11755-67. doi: 10.1021/acs.joc.5b01418. Epub 2015 Oct 16.

PMID:
26439974
26.

Densely Substituted L-Proline Esters as Catalysts for Asymmetric Michael Additions of Ketones to Nitroalkenes.

Ruiz-Olalla A, Retamosa Mde G, Cossío FP.

J Org Chem. 2015 Jun 5;80(11):5588-99. doi: 10.1021/acs.joc.5b00495. Epub 2015 May 27.

PMID:
25974363
27.

Synthesis of radiolabelled aryl azides from diazonium salts: experimental and computational results permit the identification of the preferred mechanism.

Joshi SM, de Cózar A, Gómez-Vallejo V, Koziorowski J, Llop J, Cossío FP.

Chem Commun (Camb). 2015 May 28;51(43):8954-7. doi: 10.1039/c5cc01913c.

28.

Development and validation of a LC-MS assay for the quantification of ikh12 a novel anti-tumor candidate in rat plasma and tissues and its application in a pharmacokinetic study.

Otaegui D, Masdeu C, Aldaba E, Vara Y, Zubia A, San Sebastian E, Alcalá M, Villafruela S, Cossío FP, Rodriguez-Gascón A.

Biomed Chromatogr. 2015 Aug;29(8):1249-58. doi: 10.1002/bmc.3414. Epub 2015 Jan 23.

PMID:
25616154
29.

Is it possible to achieve a complete desaturation of cycloalkanes promoted by o-benzyne?

Cervantes-Navarro F, de Cózar A, Cossío FP, Fernández-Herrera MA, Merino G, Fernández I.

Chem Commun (Camb). 2015 Mar 28;51(25):5302-5. doi: 10.1039/c4cc07311h.

PMID:
25360459
30.

Azavinylidenephosphoranes: a class of cyclic push-pull carbenes.

Lavigne F, El Kazzi A, Escudié Y, Maerten E, Kato T, Saffon-Merceron N, Branchadell V, Cossío FP, Baceiredo A.

Chemistry. 2014 Sep 22;20(39):12528-36. doi: 10.1002/chem.201402880. Epub 2014 Aug 14.

PMID:
25123091
31.

Applied computational chemistry.

Fernández I, Cossío FP.

Chem Soc Rev. 2014 Jul 21;43(14):4906-8. doi: 10.1039/c4cs90040e. Epub 2014 Jun 11. No abstract available.

PMID:
24916854
32.

Aromaticity in transition structures.

Schleyer Pv, Wu JI, Cossío FP, Fernández I.

Chem Soc Rev. 2014 Jul 21;43(14):4909-21. doi: 10.1039/c4cs00012a.

PMID:
24638823
33.

Ene-ene-yne reactions: activation strain analysis and the role of aromaticity.

Fernández I, Bickelhaupt FM, Cossío FP.

Chemistry. 2014 Aug 18;20(34):10791-801. doi: 10.1002/chem.201303874. Epub 2014 Feb 24.

PMID:
24616206
34.

Synthetic scope and DFT analysis of the chiral binap-gold(I) complex-catalyzed 1,3-dipolar cycloaddition of azlactones with alkenes.

Martín-Rodríguez M, Castelló LM, Nájera C, Sansano JM, Larrañaga O, de Cózar A, Cossío FP.

Beilstein J Org Chem. 2013 Nov 11;9:2422-33. doi: 10.3762/bjoc.9.280. eCollection 2013.

35.

Stereodivergent synthesis of chiral fullerenes by [3 + 2] cycloadditions to C₆₀.

Maroto EE, Filippone S, Suárez M, Martínez-Álvarez R, de Cózar A, Cossío FP, Martín N.

J Am Chem Soc. 2014 Jan 15;136(2):705-12. doi: 10.1021/ja410408c. Epub 2014 Jan 3.

36.

Aggregation and cooperative effects in the aldol reactions of lithium enolates.

Larrañaga O, de Cózar A, Bickelhaupt FM, Zangi R, Cossío FP.

Chemistry. 2013 Oct 4;19(41):13761-73. doi: 10.1002/chem.201301597. Epub 2013 Aug 21.

PMID:
23964002
37.

Phosphoramidite-Cu(OTf)2 complexes as chiral catalysts for 1,3-dipolar cycloaddition of iminoesters and nitroalkenes.

Castelló LM, Nájera C, Sansano JM, Larrañaga O, de Cózar A, Cossío FP.

Org Lett. 2013 Jun 21;15(12):2902-5. doi: 10.1021/ol4006618. Epub 2013 Jun 11.

PMID:
23755738
38.

Design, synthesis, and functional evaluation of leukocyte function associated antigen-1 antagonists in early and late stages of cancer development.

San Sebastián E, Zimmerman T, Zubia A, Vara Y, Martin E, Sirockin F, Dejaegere A, Stote RH, Lopez X, Pantoja-Uceda D, Valcárcel M, Mendoza L, Vidal-Vanaclocha F, Cossío FP, Blanco FJ.

J Med Chem. 2013 Feb 14;56(3):735-47. doi: 10.1021/jm3016848. Epub 2013 Jan 22.

PMID:
23339734
39.

Computational insights on the possibility of tri-coordinated cisplatinated adducts with protein models.

Ortega-Carrasco E, Cossío FP, Lledós A, Maréchal JD.

J Inorg Biochem. 2012 Dec;117:230-6. doi: 10.1016/j.jinorgbio.2012.09.020. Epub 2012 Sep 28.

PMID:
23103078
40.

Type-I dyotropic reactions: understanding trends in barriers.

Fernández I, Bickelhaupt FM, Cossío FP.

Chemistry. 2012 Sep 24;18(39):12395-403. doi: 10.1002/chem.201200897. Epub 2012 Aug 22.

PMID:
22915249
41.

Biodistribution and metabolism of 11C-labeled Kendine 91 in mice and rats.

Gómez-Vallejo V, Martín A, Aginagalde M, San Sebastian E, Padro D, Cossío FP, Llop J.

Appl Radiat Isot. 2012 Oct;70(10):2545-51. doi: 10.1016/j.apradiso.2012.05.020. Epub 2012 Jun 9.

PMID:
22871302
42.

Synthesis of 11C-labeled Kendine 91, a histone deacetylase inhibitor.

Aginagalde M, Gómez-Vallejo V, Vara Y, Cossío FP, Llop J.

Appl Radiat Isot. 2012 Oct;70(10):2552-7. doi: 10.1016/j.apradiso.2012.05.016. Epub 2012 Jun 7.

PMID:
22871301
43.

Selective "one-pot" synthesis of functionalized cyclopentenones.

Varea T, Alcalde A, López de Dicastillo C, Ramírez de Arellano C, Cossío FP, Asensio G.

J Org Chem. 2012 Jul 20;77(14):6327-31. doi: 10.1021/jo300806y. Epub 2012 Jul 2.

PMID:
22720875
44.

An amine-catalyzed enantioselective [3+2] cycloaddition of azomethine ylides and α,β-unsaturated aldehydes: applications and mechanistic implications.

Reboredo S, Reyes E, Vicario JL, Badía D, Carrillo L, de Cózar A, Cossío FP.

Chemistry. 2012 Jun 4;18(23):7179-88. doi: 10.1002/chem.201103015. Epub 2012 Apr 18.

PMID:
22511528
45.

Regioselective preparation of benzo[b]furans from phenols and α-bromoketones.

Arias L, Vara Y, Cossío FP.

J Org Chem. 2012 Jan 6;77(1):266-75. doi: 10.1021/jo201841y. Epub 2011 Dec 12.

PMID:
22122090
46.

Binap-gold(I) versus Binap-silver trifluoroacetate complexes as catalysts in 1,3-dipolar cycloadditions of azomethine ylides.

Martín-Rodríguez M, Nájera C, Sansano JM, de Cózar A, Cossío FP.

Chemistry. 2011 Dec 9;17(50):14224-33. doi: 10.1002/chem.201101606. Epub 2011 Nov 8.

PMID:
22069224
47.

Changes in fluorescent emission due to non-covalent interactions as a general detection procedure for thin-layer chromatography.

Cebolla VL, Mateos E, Garriga R, Jarne C, Membrado L, Cossío FP, Gálvez EM, Matt M, Delgado-Camón A.

Chemphyschem. 2012 Jan 16;13(1):291-9. doi: 10.1002/cphc.201100590. Epub 2011 Nov 3.

PMID:
22052844
48.

Reversible binding of ethylene to silylene-phosphine complexes at room temperature.

Rodriguez R, Gau D, Kato T, Saffon-Merceron N, De Cózar A, Cossío FP, Baceiredo A.

Angew Chem Int Ed Engl. 2011 Oct 24;50(44):10414-6. doi: 10.1002/anie.201105097. Epub 2011 Sep 14. No abstract available.

PMID:
21915982
49.

Chiral gold(I) vs chiral silver complexes as catalysts for the enantioselective synthesis of the second generation GSK-hepatitis C virus inhibitor.

Martín-Rodríguez M, Nájera C, Sansano JM, de Cózar A, Cossío FP.

Beilstein J Org Chem. 2011;7:988-96. doi: 10.3762/bjoc.7.111. Epub 2011 Jul 19.

50.

Synthesis and reactivity of a phosphine-stabilized monogermanium analogue of alkynes.

Berthe J, Garcia JM, Ocando E, Kato T, Saffon-Merceron N, De Cózar A, Cossío FP, Baceiredo A.

J Am Chem Soc. 2011 Oct 12;133(40):15930-3. doi: 10.1021/ja2073577. Epub 2011 Sep 20.

PMID:
21913709

Supplemental Content

Loading ...
Support Center