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Items: 1 to 50 of 272

1.

Vectofusin-1 Improves Transduction of Primary Human Cells with Diverse Retroviral and Lentiviral Pseudotypes, Enabling Robust, Automated Closed-System Manufacturing.

Radek C, Bernadin O, Drechsel K, Cordes N, Pfeifer R, Sträßer P, Mormin M, Gutierrez-Guerrero A, Cosset FL, Kaiser AD, Schaser T, Galy A, Verhoeyen E, Johnston ICD.

Hum Gene Ther. 2019 Dec 3. doi: 10.1089/hum.2019.157. [Epub ahead of print]

PMID:
31578886
2.

[Extracellular maturation of hepatitis C virus: a plasma cloak of invisibility].

Chanut M, Granier C, Cosset FL, Denolly S.

Med Sci (Paris). 2019 Aug-Sep;35(8-9):616-618. doi: 10.1051/medsci/2019120. Epub 2019 Sep 18. French. No abstract available.

PMID:
31532369
3.

Enveloped viruses distinct from HBV induce dissemination of hepatitis D virus in vivo.

Perez-Vargas J, Amirache F, Boson B, Mialon C, Freitas N, Sureau C, Fusil F, Cosset FL.

Nat Commun. 2019 May 8;10(1):2098. doi: 10.1038/s41467-019-10117-z.

4.

A Recurrent Activating Missense Mutation in Waldenström Macroglobulinemia Affects the DNA Binding of the ETS Transcription Factor SPI1 and Enhances Proliferation.

Roos-Weil D, Decaudin C, Armand M, Della-Valle V, Diop MK, Ghamlouch H, Ropars V, Hérate C, Lara D, Durot E, Haddad R, Mylonas E, Damm F, Pflumio F, Stoilova B, Metzner M, Elemento O, Dessen P, Camara-Clayette V, Cosset FL, Verhoeyen E, Leblond V, Ribrag V, Cornillet-Lefebvre P, Rameau P, Azar N, Charlotte F, Morel P, Charbonnier JB, Vyas P, Mercher T, Aoufouchi S, Droin N, Guillouf C, Nguyen-Khac F, Bernard OA.

Cancer Discov. 2019 Jun;9(6):796-811. doi: 10.1158/2159-8290.CD-18-0873. Epub 2019 Apr 24.

PMID:
31018969
5.

Sensing of cell-associated HTLV by plasmacytoid dendritic cells is regulated by dense β-galactoside glycosylation.

Assil S, Futsch N, Décembre E, Alais S, Gessain A, Cosset FL, Mahieux R, Dreux M, Dutartre H.

PLoS Pathog. 2019 Feb 28;15(2):e1007589. doi: 10.1371/journal.ppat.1007589. eCollection 2019 Feb.

6.

Baboon envelope LVs efficiently transduced human adult, fetal, and progenitor T cells and corrected SCID-X1 T-cell deficiency.

Bernadin O, Amirache F, Girard-Gagnepain A, Moirangthem RD, Lévy C, Ma K, Costa C, Nègre D, Reimann C, Fenard D, Cieslak A, Asnafi V, Sadek H, Mhaidly R, Cavazzana M, Lagresle-Peyrou C, Cosset FL, André I, Verhoeyen E.

Blood Adv. 2019 Feb 12;3(3):461-475. doi: 10.1182/bloodadvances.2018027508.

7.

Overview of HCV Life Cycle with a Special Focus on Current and Possible Future Antiviral Targets.

Alazard-Dany N, Denolly S, Boson B, Cosset FL.

Viruses. 2019 Jan 6;11(1). pii: E30. doi: 10.3390/v11010030. Review.

8.

Genome editing in primary cells and in vivo using viral-derived Nanoblades loaded with Cas9-sgRNA ribonucleoproteins.

Mangeot PE, Risson V, Fusil F, Marnef A, Laurent E, Blin J, Mournetas V, Massouridès E, Sohier TJM, Corbin A, Aubé F, Teixeira M, Pinset C, Schaeffer L, Legube G, Cosset FL, Verhoeyen E, Ohlmann T, Ricci EP.

Nat Commun. 2019 Jan 3;10(1):45. doi: 10.1038/s41467-018-07845-z.

9.

Membrane Fusion Assays for Studying Entry Hepatitis C Virus into Cells.

Denolly S, Cosset FL, Freitas N.

Methods Mol Biol. 2019;1911:219-234. doi: 10.1007/978-1-4939-8976-8_15.

PMID:
30593629
10.

A serum protein factor mediates maturation and apoB-association of HCV particles in the extracellular milieu.

Denolly S, Granier C, Fontaine N, Pozzetto B, Bourlet T, Guérin M, Cosset FL.

J Hepatol. 2019 Apr;70(4):626-638. doi: 10.1016/j.jhep.2018.11.033. Epub 2018 Dec 14.

PMID:
30553840
11.

Pharmacological Induction of a Progenitor State for the Efficient Expansion of Primary Human Hepatocytes.

Unzu C, Planet E, Brandenberg N, Fusil F, Cassano M, Perez-Vargas J, Friedli M, Cosset FL, Lutolf MP, Wildhaber BE, Trono D.

Hepatology. 2019 May;69(5):2214-2231. doi: 10.1002/hep.30425. Epub 2019 Feb 14.

12.

Evolution of Hepatitis B Virus Receptor NTCP Reveals Differential Pathogenicities and Species Specificities of Hepadnaviruses in Primates, Rodents, and Bats.

Jacquet S, Pons JB, De Bernardo A, Ngoubangoye B, Cosset FL, Régis C, Etienne L, Pontier D.

J Virol. 2019 Feb 19;93(5). pii: e01738-18. doi: 10.1128/JVI.01738-18. Print 2019 Mar 1.

13.

A Novel BaEVRless-Pseudotyped γ-Globin Lentiviral Vector Drives High and Stable Fetal Hemoglobin Expression and Improves Thalassemic Erythropoiesis In Vitro.

Drakopoulou E, Georgomanoli M, Lederer CW, Kleanthous M, Costa C, Bernadin O, Cosset FL, Voskaridou E, Verhoeyen E, Papanikolaou E, Anagnou NP.

Hum Gene Ther. 2019 May;30(5):601-617. doi: 10.1089/hum.2018.022. Epub 2019 Mar 15.

PMID:
30324804
14.

Farnesoid X receptor-α is a proviral host factor for hepatitis B virus that is inhibited by ligands in vitro and in vivo.

Mouzannar K, Fusil F, Lacombe B, Ollivier A, Ménard C, Lotteau V, Cosset FL, Ramière C, André P.

FASEB J. 2019 Feb;33(2):2472-2483. doi: 10.1096/fj.201801181R. Epub 2018 Oct 11.

PMID:
30307769
15.

Direct antiviral properties of TLR ligands against HBV replication in immune-competent hepatocytes.

Lucifora J, Bonnin M, Aillot L, Fusil F, Maadadi S, Dimier L, Michelet M, Floriot O, Ollivier A, Rivoire M, Ait-Goughoulte M, Daffis S, Fletcher SP, Salvetti A, Cosset FL, Zoulim F, Durantel D.

Sci Rep. 2018 Mar 29;8(1):5390. doi: 10.1038/s41598-018-23525-w.

16.

A protein coevolution method uncovers critical features of the Hepatitis C Virus fusion mechanism.

Douam F, Fusil F, Enguehard M, Dib L, Nadalin F, Schwaller L, Hrebikova G, Mancip J, Mailly L, Montserret R, Ding Q, Maisse C, Carlot E, Xu K, Verhoeyen E, Baumert TF, Ploss A, Carbone A, Cosset FL, Lavillette D.

PLoS Pathog. 2018 Mar 5;14(3):e1006908. doi: 10.1371/journal.ppat.1006908. eCollection 2018 Mar.

17.

Measles virus envelope pseudotyped lentiviral vectors transduce quiescent human HSCs at an efficiency without precedent.

Lévy C, Amirache F, Girard-Gagnepain A, Frecha C, Roman-Rodríguez FJ, Bernadin O, Costa C, Nègre D, Gutierrez-Guerrero A, Vranckx LS, Clerc I, Taylor N, Thielecke L, Cornils K, Bueren JA, Rio P, Gijsbers R, Cosset FL, Verhoeyen E.

Blood Adv. 2017 Oct 24;1(23):2088-2104. doi: 10.1182/bloodadvances.2017007773. eCollection 2017 Oct 24.

18.

The amino-terminus of the hepatitis C virus (HCV) p7 viroporin and its cleavage from glycoprotein E2-p7 precursor determine specific infectivity and secretion levels of HCV particle types.

Denolly S, Mialon C, Bourlet T, Amirache F, Penin F, Lindenbach B, Boson B, Cosset FL.

PLoS Pathog. 2017 Dec 18;13(12):e1006774. doi: 10.1371/journal.ppat.1006774. eCollection 2017 Dec.

19.

Detection of the hepatitis B virus (HBV) covalently-closed-circular DNA (cccDNA) in mice transduced with a recombinant AAV-HBV vector.

Lucifora J, Salvetti A, Marniquet X, Mailly L, Testoni B, Fusil F, Inchauspé A, Michelet M, Michel ML, Levrero M, Cortez P, Baumert TF, Cosset FL, Challier C, Zoulim F, Durantel D.

Antiviral Res. 2017 Sep;145:14-19. doi: 10.1016/j.antiviral.2017.07.006. Epub 2017 Jul 11.

PMID:
28709657
20.

Polo-like-kinase 1 is a proviral host factor for hepatitis B virus replication.

Diab A, Foca A, Fusil F, Lahlali T, Jalaguier P, Amirache F, N'Guyen L, Isorce N, Cosset FL, Zoulim F, Andrisani O, Durantel D.

Hepatology. 2017 Dec;66(6):1750-1765. doi: 10.1002/hep.29236. Epub 2017 Nov 6.

21.

A master regulator of tight junctions involved in hepatitis C virus entry and pathogenesis.

Denolly S, Cosset FL.

Hepatology. 2017 May;65(5):1756-1758. doi: 10.1002/hep.29066. Epub 2017 Mar 30. No abstract available.

PMID:
28177536
22.

Hepatitis C virus has a genetically determined lymphotropism through co-receptor B7.2.

Chen CL, Huang JY, Wang CH, Tahara SM, Zhou L, Kondo Y, Schechter J, Su L, Lai MM, Wakita T, Cosset FL, Jung JU, Machida K.

Nat Commun. 2017 Jan 9;8:13882. doi: 10.1038/ncomms13882.

23.

Gene Therapy in Fanconi Anemia: A Matter of Time, Safety and Gene Transfer Tool Efficiency.

Verhoeyen E, Roman-Rodriguez FJ, Cosset FL, Levy C, Rio P.

Curr Gene Ther. 2017;16(5):297-308. doi: 10.2174/1566523217666170109114309. Review.

PMID:
28067165
24.

A Point Mutation in the N-Terminal Amphipathic Helix α0 in NS3 Promotes Hepatitis C Virus Assembly by Altering Core Localization to the Endoplasmic Reticulum and Facilitating Virus Budding.

Yan Y, He Y, Boson B, Wang X, Cosset FL, Zhong J.

J Virol. 2017 Feb 28;91(6). pii: e02399-16. doi: 10.1128/JVI.02399-16. Print 2017 Mar 15.

25.

Daclatasvir Prevents Hepatitis C Virus Infectivity by Blocking Transfer of the Viral Genome to Assembly Sites.

Boson B, Denolly S, Turlure F, Chamot C, Dreux M, Cosset FL.

Gastroenterology. 2017 Mar;152(4):895-907.e14. doi: 10.1053/j.gastro.2016.11.047. Epub 2016 Dec 5.

26.

Baboon envelope pseudotyped lentiviral vectors: a highly efficient new tool to genetically manipulate T-cell acute lymphoblastic leukaemia-initiating cells.

Costa C, Hypolite G, Bernadin O, Lévy C, Cosset FL, Asnafi V, Macintyre E, Verhoeyen E, Tesio M.

Leukemia. 2017 Apr;31(4):977-980. doi: 10.1038/leu.2016.372. Epub 2016 Dec 6. No abstract available.

PMID:
27922597
27.

Gene-corrected human Munc13-4-deficient CD8+ T cells can efficiently restrict EBV-driven lymphoproliferation in immunodeficient mice.

Soheili T, Rivière J, Ricciardelli I, Durand A, Verhoeyen E, Derrien AC, Lagresle-Peyrou C, de Saint Basile G, Cosset FL, Amrolia P, André-Schmutz I, Cavazzana M.

Blood. 2016 Dec 15;128(24):2859-2862. Epub 2016 Oct 31. No abstract available.

PMID:
27799161
28.

Solute Carrier NTCP Regulates Innate Antiviral Immune Responses Targeting Hepatitis C Virus Infection of Hepatocytes.

Verrier ER, Colpitts CC, Bach C, Heydmann L, Zona L, Xiao F, Thumann C, Crouchet E, Gaudin R, Sureau C, Cosset FL, McKeating JA, Pessaux P, Hoshida Y, Schuster C, Zeisel MB, Baumert TF.

Cell Rep. 2016 Oct 25;17(5):1357-1368. doi: 10.1016/j.celrep.2016.09.084.

29.

Baboon envelope pseudotyped lentiviral vectors efficiently transduce human B cells and allow active factor IX B cell secretion in vivo in NOD/SCIDγc-/- mice.

Levy C, Fusil F, Amirache F, Costa C, Girard-Gagnepain A, Negre D, Bernadin O, Garaulet G, Rodriguez A, Nair N, Vandendriessche T, Chuah M, Cosset FL, Verhoeyen E.

J Thromb Haemost. 2016 Dec;14(12):2478-2492. doi: 10.1111/jth.13520. Epub 2016 Nov 8.

30.

T- and B-cell responses to multivalent prime-boost DNA and viral vectored vaccine combinations against hepatitis C virus in non-human primates.

Rollier CS, Verschoor EJ, Verstrepen BE, Drexhage JA, Paranhos-Baccala G, Liljeström P, Sutter G, Arribillaga L, Lasarte JJ, Bartosch B, Cosset FL, Inchauspe G, Heeney JL.

Gene Ther. 2016 Oct;23(10):753-759. doi: 10.1038/gt.2016.55. Epub 2016 Jul 14.

PMID:
27416077
31.

X-linked primary immunodeficiency associated with hemizygous mutations in the moesin (MSN) gene.

Lagresle-Peyrou C, Luce S, Ouchani F, Soheili TS, Sadek H, Chouteau M, Durand A, Pic I, Majewski J, Brouzes C, Lambert N, Bohineust A, Verhoeyen E, Cosset FL, Magerus-Chatinet A, Rieux-Laucat F, Gandemer V, Monnier D, Heijmans C, van Gijn M, Dalm VA, Mahlaoui N, Stephan JL, Picard C, Durandy A, Kracker S, Hivroz C, Jabado N, de Saint Basile G, Fischer A, Cavazzana M, André-Schmutz I.

J Allergy Clin Immunol. 2016 Dec;138(6):1681-1689.e8. doi: 10.1016/j.jaci.2016.04.032. Epub 2016 Jun 4.

PMID:
27405666
32.

Triggering the TCR Developmental Checkpoint Activates a Therapeutically Targetable Tumor Suppressive Pathway in T-cell Leukemia.

Trinquand A, Dos Santos NR, Tran Quang C, Rocchetti F, Zaniboni B, Belhocine M, Da Costa de Jesus C, Lhermitte L, Tesio M, Dussiot M, Cosset FL, Verhoeyen E, Pflumio F, Ifrah N, Dombret H, Spicuglia S, Chatenoud L, Gross DA, Hermine O, Macintyre E, Ghysdael J, Asnafi V.

Cancer Discov. 2016 Sep;6(9):972-85. doi: 10.1158/2159-8290.CD-15-0675. Epub 2016 Jun 28.

33.

Haploinsufficiency for NR3C1, the gene encoding the glucocorticoid receptor, in blastic plasmacytoid dendritic cell neoplasms.

Emadali A, Hoghoughi N, Duley S, Hajmirza A, Verhoeyen E, Cosset FL, Bertrand P, Roumier C, Roggy A, Suchaud-Martin C, Chauvet M, Bertrand S, Hamaidia S, Rousseaux S, Josserand V, Charles J, Templier I, Maeda T, Bruder-Costa J, Chaperot L, Plumas J, Jacob MC, Bonnefoix T, Park S, Gressin R, Tensen CP, Mecucci C, Macintyre E, Leroux D, Brambilla E, Nguyen-Khac F, Luquet I, Penther D, Bastard C, Jardin F, Lefebvre C, Garnache F, Callanan MB.

Blood. 2016 Jun 16;127(24):3040-53. doi: 10.1182/blood-2015-09-671040. Epub 2016 Apr 8.

34.

Addressing the next challenges: A summary of the 22nd international symposium on hepatitis C virus and related viruses.

Baumert TF, Schuster C, Cosset FL, Dubuisson J, Hofmann M, Tautz N, Zeisel MB, Thimme R.

J Hepatol. 2016 Apr;64(4):968-73. doi: 10.1016/j.jhep.2015.12.021. Epub 2016 Jan 11. Review.

PMID:
26780288
35.

Specialization of Hepatitis C Virus Envelope Glycoproteins for B Lymphocytes in Chronically Infected Patients.

Douam F, Bobay LM, Maurin G, Fresquet J, Calland N, Maisse C, Durand T, Cosset FL, Féray C, Lavillette D.

J Virol. 2015 Nov 4;90(2):992-1008. doi: 10.1128/JVI.02516-15. Print 2016 Jan 15.

36.

Atad2 is a generalist facilitator of chromatin dynamics in embryonic stem cells.

Morozumi Y, Boussouar F, Tan M, Chaikuad A, Jamshidikia M, Colak G, He H, Nie L, Petosa C, de Dieuleveult M, Curtet S, Vitte AL, Rabatel C, Debernardi A, Cosset FL, Verhoeyen E, Emadali A, Schweifer N, Gianni D, Gut M, Guardiola P, Rousseaux S, Gérard M, Knapp S, Zhao Y, Khochbin S.

J Mol Cell Biol. 2016 Aug;8(4):349-62. doi: 10.1093/jmcb/mjv060. Epub 2015 Oct 12.

37.

The mycotoxin aflatoxin B1 stimulates Epstein-Barr virus-induced B-cell transformation in in vitro and in vivo experimental models.

Accardi R, Gruffat H, Sirand C, Fusil F, Gheit T, Hernandez-Vargas H, Le Calvez-Kelm F, Traverse-Glehen A, Cosset FL, Manet E, Wild CP, Tommasino M.

Carcinogenesis. 2015 Nov;36(11):1440-51. doi: 10.1093/carcin/bgv142. Epub 2015 Sep 30.

PMID:
26424750
38.

Determinants Involved in Hepatitis C Virus and GB Virus B Primate Host Restriction.

Marnata C, Saulnier A, Mompelat D, Krey T, Cohen L, Boukadida C, Warter L, Fresquet J, Vasiliauskaite I, Escriou N, Cosset FL, Rey FA, Lanford RE, Karayiannis P, Rose NJ, Lavillette D, Martin A.

J Virol. 2015 Dec;89(23):12131-44. doi: 10.1128/JVI.01161-15. Epub 2015 Sep 23.

39.

Surface engineering of lentiviral vectors for gene transfer into gene therapy target cells.

Lévy C, Verhoeyen E, Cosset FL.

Curr Opin Pharmacol. 2015 Oct;24:79-85. doi: 10.1016/j.coph.2015.08.003. Epub 2015 Aug 25. Review.

PMID:
26298515
40.

A Lentiviral Vector Allowing Physiologically Regulated Membrane-anchored and Secreted Antibody Expression Depending on B-cell Maturation Status.

Fusil F, Calattini S, Amirache F, Mancip J, Costa C, Robbins JB, Douam F, Lavillette D, Law M, Defrance T, Verhoeyen E, Cosset FL.

Mol Ther. 2015 Nov;23(11):1734-1747. doi: 10.1038/mt.2015.148. Epub 2015 Aug 18.

41.

Hepatitis C Virus Envelope Glycoprotein E1 Forms Trimers at the Surface of the Virion.

Falson P, Bartosch B, Alsaleh K, Tews BA, Loquet A, Ciczora Y, Riva L, Montigny C, Montpellier C, Duverlie G, Pécheur EI, le Maire M, Cosset FL, Dubuisson J, Penin F.

J Virol. 2015 Oct;89(20):10333-46. doi: 10.1128/JVI.00991-15. Epub 2015 Aug 5.

42.

Functional and Biochemical Characterization of Hepatitis C Virus (HCV) Particles Produced in a Humanized Liver Mouse Model.

Calattini S, Fusil F, Mancip J, Dao Thi VL, Granier C, Gadot N, Scoazec JY, Zeisel MB, Baumert TF, Lavillette D, Dreux M, Cosset FL.

J Biol Chem. 2015 Sep 18;290(38):23173-87. doi: 10.1074/jbc.M115.662999. Epub 2015 Jul 29.

43.

Infection of Human Liver Myofibroblasts by Hepatitis C Virus: A Direct Mechanism of Liver Fibrosis in Hepatitis C.

Aoudjehane L, Bisch G, Scatton O, Granier C, Gaston J, Housset C, Roingeard P, Cosset FL, Perdigao F, Balladur P, Wakita T, Calmus Y, Conti F.

PLoS One. 2015 Jul 27;10(7):e0134141. doi: 10.1371/journal.pone.0134141. eCollection 2015.

44.

Low cross-neutralization of hepatitis C correlates with liver disease in immunocompromized patients.

Maurin G, Halgand B, Bruscella P, Fresquet J, Duclos-Vallée JC, Roque-Afonso AM, Cosset FL, Samuel D, Lavillette D, Féray C.

AIDS. 2015 Jun 1;29(9):1025-33. doi: 10.1097/QAD.0000000000000651.

PMID:
26125137
45.

Acute hepatitis C virus infection induces anti-host cell receptor antibodies with virus-neutralizing properties.

Tawar RG, Colpitts CC, Timm J, Fehm T, Roggendorf M, Meisel H, Meyer N, Habersetzer F, Cosset FL, Berg T, Zeisel MB, Baumert TF.

Hepatology. 2015 Sep;62(3):726-36. doi: 10.1002/hep.27906. Epub 2015 Jul 28.

PMID:
26010076
46.

Heparan sulfate-dependent enhancement of henipavirus infection.

Mathieu C, Dhondt KP, Châlons M, Mély S, Raoul H, Negre D, Cosset FL, Gerlier D, Vivès RR, Horvat B.

MBio. 2015 Mar 10;6(2):e02427. doi: 10.1128/mBio.02427-14.

47.

Towards an HBV cure: state-of-the-art and unresolved questions--report of the ANRS workshop on HBV cure.

Zeisel MB, Lucifora J, Mason WS, Sureau C, Beck J, Levrero M, Kann M, Knolle PA, Benkirane M, Durantel D, Michel ML, Autran B, Cosset FL, Strick-Marchand H, Trépo C, Kao JH, Carrat F, Lacombe K, Schinazi RF, Barré-Sinoussi F, Delfraissy JF, Zoulim F.

Gut. 2015 Aug;64(8):1314-26. doi: 10.1136/gutjnl-2014-308943. Epub 2015 Feb 10. Review.

PMID:
25670809
48.

The mechanism of HCV entry into host cells.

Douam F, Lavillette D, Cosset FL.

Prog Mol Biol Transl Sci. 2015;129:63-107. doi: 10.1016/bs.pmbts.2014.10.003. Epub 2014 Dec 12. Review.

PMID:
25595801
49.

Virology and cell biology of the hepatitis C virus life cycle: an update.

Dubuisson J, Cosset FL.

J Hepatol. 2014 Nov;61(1 Suppl):S3-S13. doi: 10.1016/j.jhep.2014.06.031. Epub 2014 Nov 3. Review.

50.

ADAR1 enhances HTLV-1 and HTLV-2 replication through inhibition of PKR activity.

Cachat A, Alais S, Chevalier SA, Journo C, Fusil F, Dutartre H, Boniface A, Ko NL, Gessain A, Cosset FL, Suspène R, Vartanian JP, Mahieux R.

Retrovirology. 2014 Nov 12;11:93. doi: 10.1186/s12977-014-0093-9.

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