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Items: 14

1.

A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to β-Cell Mitochondrial Dysfunction in Type 2 Diabetes.

Peiris H, Duffield MD, Fadista J, Jessup CF, Kashmir V, Genders AJ, McGee SL, Martin AM, Saiedi M, Morton N, Carter R, Cousin MA, Kokotos AC, Oskolkov N, Volkov P, Hough TA, Fisher EM, Tybulewicz VL, Busciglio J, Coskun PE, Becker A, Belichenko PV, Mobley WC, Ryan MT, Chan JY, Laybutt DR, Coates PT, Yang S, Ling C, Groop L, Pritchard MA, Keating DJ.

PLoS Genet. 2016 May 19;12(5):e1006033. doi: 10.1371/journal.pgen.1006033. eCollection 2016 May.

2.

Differential gene expression reveals mitochondrial dysfunction in an imprinting center deletion mouse model of Prader-Willi syndrome.

Yazdi PG, Su H, Ghimbovschi S, Fan W, Coskun PE, Nalbandian A, Knoblach S, Resnick JL, Hoffman E, Wallace DC, Kimonis VE.

Clin Transl Sci. 2013 Oct;6(5):347-55. doi: 10.1111/cts.12083. Epub 2013 Jul 29.

3.

Oxidative Stress and Mitochondrial Dysfunction in Down's Syndrome: Relevance to Aging and Dementia.

Coskun PE, Busciglio J.

Curr Gerontol Geriatr Res. 2012;2012:383170. doi: 10.1155/2012/383170. Epub 2012 Apr 29.

4.

Systemic mitochondrial dysfunction and the etiology of Alzheimer's disease and down syndrome dementia.

Coskun PE, Wyrembak J, Derbereva O, Melkonian G, Doran E, Lott IT, Head E, Cotman CW, Wallace DC.

J Alzheimers Dis. 2010;20 Suppl 2:S293-310. doi: 10.3233/JAD-2010-100351.

5.

Mitochondrial dysfunction in CA1 hippocampal neurons of the UBE3A deficient mouse model for Angelman syndrome.

Su H, Fan W, Coskun PE, Vesa J, Gold JA, Jiang YH, Potluri P, Procaccio V, Acab A, Weiss JH, Wallace DC, Kimonis VE.

Neurosci Lett. 2011 Jan 7;487(2):129-33. doi: 10.1016/j.neulet.2009.06.079. Epub 2009 Jun 27.

6.

MITOCHIP assessment of differential gene expression in the skeletal muscle of Ant1 knockout mice: coordinate regulation of OXPHOS, antioxidant, and apoptotic genes.

Subramaniam V, Golik P, Murdock DG, Levy S, Kerstann KW, Coskun PE, Melkonian GA, Wallace DC.

Biochim Biophys Acta. 2008 Jul-Aug;1777(7-8):666-75. doi: 10.1016/j.bbabio.2008.03.015. Epub 2008 Mar 28.

7.

A mouse model of mitochondrial disease reveals germline selection against severe mtDNA mutations.

Fan W, Waymire KG, Narula N, Li P, Rocher C, Coskun PE, Vannan MA, Narula J, Macgregor GR, Wallace DC.

Science. 2008 Feb 15;319(5865):958-62. doi: 10.1126/science.1147786.

8.

Extension of murine life span by overexpression of catalase targeted to mitochondria.

Schriner SE, Linford NJ, Martin GM, Treuting P, Ogburn CE, Emond M, Coskun PE, Ladiges W, Wolf N, Van Remmen H, Wallace DC, Rabinovitch PS.

Science. 2005 Jun 24;308(5730):1909-11. Epub 2005 May 5.

9.

Adeno-associated virus-mediated gene transfer of the heart/muscle adenine nucleotide translocator (ANT) in mouse.

Flierl A, Chen Y, Coskun PE, Samulski RJ, Wallace DC.

Gene Ther. 2005 Apr;12(7):570-8.

10.

Alzheimer's brains harbor somatic mtDNA control-region mutations that suppress mitochondrial transcription and replication.

Coskun PE, Beal MF, Wallace DC.

Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10726-31. Epub 2004 Jul 9.

11.

Control region mtDNA variants: longevity, climatic adaptation, and a forensic conundrum.

Coskun PE, Ruiz-Pesini E, Wallace DC.

Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2174-6. Epub 2003 Feb 26. No abstract available.

12.

Lifespan extension and rescue of spongiform encephalopathy in superoxide dismutase 2 nullizygous mice treated with superoxide dismutase-catalase mimetics.

Melov S, Doctrow SR, Schneider JA, Haberson J, Patel M, Coskun PE, Huffman K, Wallace DC, Malfroy B.

J Neurosci. 2001 Nov 1;21(21):8348-53.

13.

Mitochondrial DNA rearrangements in aging human brain and in situ PCR of mtDNA.

Melov S, Schneider JA, Coskun PE, Bennett DA, Wallace DC.

Neurobiol Aging. 1999 Sep-Oct;20(5):565-71.

PMID:
10638530
14.

Mouse models of mitochondrial disease, oxidative stress, and senescence.

Melov S, Coskun PE, Wallace DC.

Mutat Res. 1999 Jul 30;434(3):233-42. Review.

PMID:
10486594

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