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Items: 39

1.

ALS-Linked Mutations Affect UBQLN2 Oligomerization and Phase Separation in a Position- and Amino Acid-Dependent Manner.

Dao TP, Martyniak B, Canning AJ, Lei Y, Colicino EG, Cosgrove MS, Hehnly H, Castañeda CA.

Structure. 2019 Jun 4;27(6):937-951.e5. doi: 10.1016/j.str.2019.03.012. Epub 2019 Apr 11.

PMID:
30982635
2.

High affinity binding of H3K14ac through collaboration of bromodomains 2, 4 and 5 is critical for the molecular and tumor suppressor functions of PBRM1.

Liao L, Alicea-Velázquez NL, Langbein L, Niu X, Cai W, Cho EA, Zhang M, Greer CB, Yan Q, Cosgrove MS, Yang H.

Mol Oncol. 2019 Apr;13(4):811-828. doi: 10.1002/1878-0261.12434. Epub 2019 Feb 2.

3.

Small Molecule-Induced Domain Swapping as a Mechanism for Controlling Protein Function and Assembly.

Karchin JM, Ha JH, Namitz KE, Cosgrove MS, Loh SN.

Sci Rep. 2017 Mar 13;7:44388. doi: 10.1038/srep44388.

4.

Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes.

Alicea-Velázquez NL, Shinsky SA, Loh DM, Lee JH, Skalnik DG, Cosgrove MS.

J Biol Chem. 2016 Oct 21;291(43):22357-22372. Epub 2016 Aug 25.

5.

Protein-like Nanoparticles Based on Orthogonal Self-Assembly of Chimeric Peptides.

Jiang L, Xu D, Namitz KE, Cosgrove MS, Lund R, Dong H.

Small. 2016 Oct;12(37):5126-5131. doi: 10.1002/smll.201600910. Epub 2016 Aug 9.

PMID:
27503402
6.

Data publication with the structural biology data grid supports live analysis.

Meyer PA, Socias S, Key J, Ransey E, Tjon EC, Buschiazzo A, Lei M, Botka C, Withrow J, Neau D, Rajashankar K, Anderson KS, Baxter RH, Blacklow SC, Boggon TJ, Bonvin AM, Borek D, Brett TJ, Caflisch A, Chang CI, Chazin WJ, Corbett KD, Cosgrove MS, Crosson S, Dhe-Paganon S, Di Cera E, Drennan CL, Eck MJ, Eichman BF, Fan QR, Ferré-D'Amaré AR, Fromme JC, Garcia KC, Gaudet R, Gong P, Harrison SC, Heldwein EE, Jia Z, Keenan RJ, Kruse AC, Kvansakul M, McLellan JS, Modis Y, Nam Y, Otwinowski Z, Pai EF, Pereira PJ, Petosa C, Raman CS, Rapoport TA, Roll-Mecak A, Rosen MK, Rudenko G, Schlessinger J, Schwartz TU, Shamoo Y, Sondermann H, Tao YJ, Tolia NH, Tsodikov OV, Westover KD, Wu H, Foster I, Fraser JS, Maia FR, Gonen T, Kirchhausen T, Diederichs K, Crosas M, Sliz P.

Nat Commun. 2016 Mar 7;7:10882. doi: 10.1038/ncomms10882.

7.

Unique Role of the WD-40 Repeat Protein 5 (WDR5) Subunit within the Mixed Lineage Leukemia 3 (MLL3) Histone Methyltransferase Complex.

Shinsky SA, Cosgrove MS.

J Biol Chem. 2015 Oct 23;290(43):25819-33. doi: 10.1074/jbc.M115.684142. Epub 2015 Aug 31.

8.

Operative care of obstetric patients.

Cosgrove MS.

Crit Care Nurs Clin North Am. 2015 Mar;27(1):89-103. doi: 10.1016/j.cnc.2014.10.003. Epub 2014 Nov 18. Review.

PMID:
25725539
9.

Infection control in the operating room.

Cosgrove MS.

Crit Care Nurs Clin North Am. 2015 Mar;27(1):79-87. doi: 10.1016/j.cnc.2014.10.004. Epub 2014 Dec 15. Review.

PMID:
25725538
10.

Biochemical reconstitution and phylogenetic comparison of human SET1 family core complexes involved in histone methylation.

Shinsky SA, Monteith KE, Viggiano S, Cosgrove MS.

J Biol Chem. 2015 Mar 6;290(10):6361-75. doi: 10.1074/jbc.M114.627646. Epub 2015 Jan 5.

11.

Characterization of the Grp94/OS-9 chaperone-lectin complex.

Seidler PM, Shinsky SA, Hong F, Li Z, Cosgrove MS, Gewirth DT.

J Mol Biol. 2014 Oct 23;426(21):3590-605. doi: 10.1016/j.jmb.2014.08.024. Epub 2014 Sep 3.

12.

A non-active-site SET domain surface crucial for the interaction of MLL1 and the RbBP5/Ash2L heterodimer within MLL family core complexes.

Shinsky SA, Hu M, Vought VE, Ng SB, Bamshad MJ, Shendure J, Cosgrove MS.

J Mol Biol. 2014 Jun 12;426(12):2283-99. doi: 10.1016/j.jmb.2014.03.011. Epub 2014 Mar 27.

13.

Trithorax monomethylates histone H3K4 and interacts directly with CBP to promote H3K27 acetylation and antagonize Polycomb silencing.

Tie F, Banerjee R, Saiakhova AR, Howard B, Monteith KE, Scacheri PC, Cosgrove MS, Harte PJ.

Development. 2014 Mar;141(5):1129-39. doi: 10.1242/dev.102392.

14.

Automethylation activities within the mixed lineage leukemia-1 (MLL1) core complex reveal evidence supporting a "two-active site" model for multiple histone H3 lysine 4 methylation.

Patel A, Vought VE, Swatkoski S, Viggiano S, Howard B, Dharmarajan V, Monteith KE, Kupakuwana G, Namitz KE, Shinsky SA, Cotter RJ, Cosgrove MS.

J Biol Chem. 2014 Jan 10;289(2):868-84. doi: 10.1074/jbc.M113.501064. Epub 2013 Nov 14.

15.

Writers and readers: deconvoluting the harmonic complexity of the histone code.

Cosgrove MS.

Nat Struct Mol Biol. 2012 Aug;19(8):739-40. doi: 10.1038/nsmb.2350. No abstract available.

PMID:
22864360
16.

Anesthesia for the adult patient with an unrepaired congenital cyanotic heart defect: a case report.

Cosgrove MS.

AANA J. 2012 Jun;80(3):197-203. Erratum in: AANA J. 2012 Aug;80(4):258.

PMID:
22848981
17.

The Bin3 RNA methyltransferase targets 7SK RNA to control transcription and translation.

Cosgrove MS, Ding Y, Rennie WA, Lane MJ, Hanes SD.

Wiley Interdiscip Rev RNA. 2012 Sep-Oct;3(5):633-47. doi: 10.1002/wrna.1123. Epub 2012 Jun 27. Review.

18.

Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.

Dharmarajan V, Lee JH, Patel A, Skalnik DG, Cosgrove MS.

J Biol Chem. 2012 Aug 10;287(33):27275-89. doi: 10.1074/jbc.M112.364125. Epub 2012 Jun 3.

19.

Allosteric activation of the phosphoinositide phosphatase Sac1 by anionic phospholipids.

Zhong S, Hsu F, Stefan CJ, Wu X, Patel A, Cosgrove MS, Mao Y.

Biochemistry. 2012 Apr 17;51(15):3170-7. doi: 10.1021/bi300086c. Epub 2012 Apr 3.

20.

Mgm101 is a Rad52-related protein required for mitochondrial DNA recombination.

Mbantenkhu M, Wang X, Nardozzi JD, Wilkens S, Hoffman E, Patel A, Cosgrove MS, Chen XJ.

J Biol Chem. 2011 Dec 9;286(49):42360-70. doi: 10.1074/jbc.M111.307512. Epub 2011 Oct 25.

21.

Myosin5a tail associates directly with Rab3A-containing compartments in neurons.

Wöllert T, Patel A, Lee YL, Provance DW Jr, Vought VE, Cosgrove MS, Mercer JA, Langford GM.

J Biol Chem. 2011 Apr 22;286(16):14352-61. doi: 10.1074/jbc.M110.187286. Epub 2011 Feb 23.

22.

A novel non-SET domain multi-subunit methyltransferase required for sequential nucleosomal histone H3 methylation by the mixed lineage leukemia protein-1 (MLL1) core complex.

Patel A, Vought VE, Dharmarajan V, Cosgrove MS.

J Biol Chem. 2011 Feb 4;286(5):3359-69. doi: 10.1074/jbc.M110.174524. Epub 2010 Nov 24. Erratum in: J Biol Chem. 2011 May 20;286(20):18344.

23.

Mixed lineage leukemia: a structure-function perspective of the MLL1 protein.

Cosgrove MS, Patel A.

FEBS J. 2010 Apr;277(8):1832-42. doi: 10.1111/j.1742-4658.2010.07609.x. Epub 2010 Mar 4. Review.

24.

On the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complex.

Patel A, Dharmarajan V, Vought VE, Cosgrove MS.

J Biol Chem. 2009 Sep 4;284(36):24242-56. doi: 10.1074/jbc.M109.014498. Epub 2009 Jun 25.

25.

Structure of WDR5 bound to mixed lineage leukemia protein-1 peptide.

Patel A, Dharmarajan V, Cosgrove MS.

J Biol Chem. 2008 Nov 21;283(47):32158-61. doi: 10.1074/jbc.C800164200. Epub 2008 Oct 1.

26.

A conserved arginine-containing motif crucial for the assembly and enzymatic activity of the mixed lineage leukemia protein-1 core complex.

Patel A, Vought VE, Dharmarajan V, Cosgrove MS.

J Biol Chem. 2008 Nov 21;283(47):32162-75. doi: 10.1074/jbc.M806317200. Epub 2008 Oct 1.

27.

Histone proteomics and the epigenetic regulation of nucleosome mobility.

Cosgrove MS.

Expert Rev Proteomics. 2007 Aug;4(4):465-78. Review.

PMID:
17705705
28.

PHinDing a new histone "effector" domain.

Cosgrove MS.

Structure. 2006 Jul;14(7):1096-8. No abstract available.

29.

The structural basis of sirtuin substrate affinity.

Cosgrove MS, Bever K, Avalos JL, Muhammad S, Zhang X, Wolberger C.

Biochemistry. 2006 Jun 20;45(24):7511-21.

PMID:
16768447
30.

Insights into the role of histone H3 and histone H4 core modifiable residues in Saccharomyces cerevisiae.

Hyland EM, Cosgrove MS, Molina H, Wang D, Pandey A, Cottee RJ, Boeke JD.

Mol Cell Biol. 2005 Nov;25(22):10060-70.

31.

How does the histone code work?

Cosgrove MS, Wolberger C.

Biochem Cell Biol. 2005 Aug;83(4):468-76. Review.

PMID:
16094450
32.

Regulated nucleosome mobility and the histone code.

Cosgrove MS, Boeke JD, Wolberger C.

Nat Struct Mol Biol. 2004 Nov;11(11):1037-43. Review.

PMID:
15523479
33.

Structure of a Sir2 enzyme bound to an acetylated p53 peptide.

Avalos JL, Celic I, Muhammad S, Cosgrove MS, Boeke JD, Wolberger C.

Mol Cell. 2002 Sep;10(3):523-35.

34.

A core nucleosome surface crucial for transcriptional silencing.

Park JH, Cosgrove MS, Youngman E, Wolberger C, Boeke JD.

Nat Genet. 2002 Oct;32(2):273-9. Epub 2002 Sep 16.

PMID:
12244315
36.

NADP+ and NAD+ binding to the dual coenzyme specific enzyme Leuconostoc mesenteroides glucose 6-phosphate dehydrogenase: different interdomain hinge angles are seen in different binary and ternary complexes.

Naylor CE, Gover S, Basak AK, Cosgrove MS, Levy HR, Adams MJ.

Acta Crystallogr D Biol Crystallogr. 2001 May;57(Pt 5):635-48. Epub 2001 Apr 24.

PMID:
11320304
37.

Delineation of the roles of amino acids involved in the catalytic functions of Leuconostoc mesenteroides glucose 6-phosphate dehydrogenase.

Vought V, Ciccone T, Davino MH, Fairbairn L, Lin Y, Cosgrove MS, Adams MJ, Levy HR.

Biochemistry. 2000 Dec 12;39(49):15012-21.

PMID:
11106479
39.

On the mechanism of the reaction catalyzed by glucose 6-phosphate dehydrogenase.

Cosgrove MS, Naylor C, Paludan S, Adams MJ, Levy HR.

Biochemistry. 1998 Mar 3;37(9):2759-67.

PMID:
9485426

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