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Items: 26


Isolation, Culture, Characterization, and Differentiation of Human Muscle Progenitor Cells from the Skeletal Muscle Biopsy Procedure.

Gheller BJ, Blum J, Soueid-Baumgarten S, Bender E, Cosgrove BD, Thalacker-Mercer A.

J Vis Exp. 2019 Aug 23;(150). doi: 10.3791/59580.


ACVR1R206H FOP mutation alters mechanosensing and tissue stiffness during heterotopic ossification.

Haupt J, Stanley A, McLeod CM, Cosgrove BD, Culbert AL, Wang L, Mourkioti F, Mauck RL, Shore EM.

Mol Biol Cell. 2019 Jan 1;30(1):17-29. doi: 10.1091/mbc.E18-05-0311. Epub 2018 Oct 31.


How Biophysical Forces Regulate Human B Cell Lymphomas.

Apoorva F, Loiben AM, Shah SB, Purwada A, Fontan L, Goldstein R, Kirby BJ, Melnick AM, Cosgrove BD, Singh A.

Cell Rep. 2018 Apr 10;23(2):499-511. doi: 10.1016/j.celrep.2018.03.069.


Publisher Correction: High-resolution myogenic lineage mapping by single-cell mass cytometry.

Porpiglia E, Samusik N, Ho ATV, Cosgrove BD, Mai T, Davis KL, Jager A, Nolan GP, Bendall SC, Fantl WJ, Blau HM.

Nat Cell Biol. 2018 Aug;20(8):990. doi: 10.1038/s41556-018-0043-1.


Mechano-adaptation of the stem cell nucleus.

Heo SJ, Cosgrove BD, Dai EN, Mauck RL.

Nucleus. 2018 Jan 1;9(1):9-19. doi: 10.1080/19491034.2017.1371398. Epub 2017 Nov 13. Review.


Injectable biomimetic liquid crystalline scaffolds enhance muscle stem cell transplantation.

Sleep E, Cosgrove BD, McClendon MT, Preslar AT, Chen CH, Sangji MH, PĂ©rez CMR, Haynes RD, Meade TJ, Blau HM, Stupp SI.

Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):E7919-E7928. doi: 10.1073/pnas.1708142114. Epub 2017 Sep 5.


Microcontact-Printed Hydrogel Microwell Arrays for Clonal Muscle Stem Cell Cultures.

Aguilar VM, Cosgrove BD.

Methods Mol Biol. 2017;1668:75-92. doi: 10.1007/978-1-4939-7283-8_6.


High-resolution myogenic lineage mapping by single-cell mass cytometry.

Porpiglia E, Samusik N, Ho ATV, Cosgrove BD, Mai T, Davis KL, Jager A, Nolan GP, Bendall SC, Fantl WJ, Blau HM.

Nat Cell Biol. 2017 May;19(5):558-567. doi: 10.1038/ncb3507. Epub 2017 Apr 17. Erratum in: Nat Cell Biol. 2018 Mar 5;:.


Cross-Linking Chemistry of Tyramine-Modified Hyaluronan Hydrogels Alters Mesenchymal Stem Cell Early Attachment and Behavior.

Loebel C, Szczesny SE, Cosgrove BD, Alini M, Zenobi-Wong M, Mauck RL, Eglin D.

Biomacromolecules. 2017 Mar 13;18(3):855-864. doi: 10.1021/acs.biomac.6b01740. Epub 2017 Feb 10.


N-cadherin adhesive interactions modulate matrix mechanosensing and fate commitment of mesenchymal stem cells.

Cosgrove BD, Mui KL, Driscoll TP, Caliari SR, Mehta KD, Assoian RK, Burdick JA, Mauck RL.

Nat Mater. 2016 Dec;15(12):1297-1306. doi: 10.1038/nmat4725. Epub 2016 Aug 15.


Mechanically Induced Chromatin Condensation Requires Cellular Contractility in Mesenchymal Stem Cells.

Heo SJ, Han WM, Szczesny SE, Cosgrove BD, Elliott DM, Lee DA, Duncan RL, Mauck RL.

Biophys J. 2016 Aug 23;111(4):864-874. doi: 10.1016/j.bpj.2016.07.006.


Stiffening hydrogels for investigating the dynamics of hepatic stellate cell mechanotransduction during myofibroblast activation.

Caliari SR, Perepelyuk M, Cosgrove BD, Tsai SJ, Lee GY, Mauck RL, Wells RG, Burdick JA.

Sci Rep. 2016 Feb 24;6:21387. doi: 10.1038/srep21387.


The central role of muscle stem cells in regenerative failure with aging.

Blau HM, Cosgrove BD, Ho AT.

Nat Med. 2015 Aug;21(8):854-62. doi: 10.1038/nm.3918. Review.


Cytoskeletal to Nuclear Strain Transfer Regulates YAP Signaling in Mesenchymal Stem Cells.

Driscoll TP, Cosgrove BD, Heo SJ, Shurden ZE, Mauck RL.

Biophys J. 2015 Jun 16;108(12):2783-93. doi: 10.1016/j.bpj.2015.05.010.


Rejuvenation of the muscle stem cell population restores strength to injured aged muscles.

Cosgrove BD, Gilbert PM, Porpiglia E, Mourkioti F, Lee SP, Corbel SY, Llewellyn ME, Delp SL, Blau HM.

Nat Med. 2014 Mar;20(3):255-64. doi: 10.1038/nm.3464. Epub 2014 Feb 16.


A high throughput mechanical screening device for cartilage tissue engineering.

Mohanraj B, Hou C, Meloni GR, Cosgrove BD, Dodge GR, Mauck RL.

J Biomech. 2014 Jun 27;47(9):2130-6. doi: 10.1016/j.jbiomech.2013.10.043. Epub 2013 Nov 8.


Model Convolution: A Computational Approach to Digital Image Interpretation.

Gardner MK, Sprague BL, Pearson CG, Cosgrove BD, Bicek AD, Bloom K, Salmon ED, Odde DJ.

Cell Mol Bioeng. 2010 Jun;3(2):163-170. Epub 2010 Feb 6.


Networks inferred from biochemical data reveal profound differences in toll-like receptor and inflammatory signaling between normal and transformed hepatocytes.

Alexopoulos LG, Saez-Rodriguez J, Cosgrove BD, Lauffenburger DA, Sorger PK.

Mol Cell Proteomics. 2010 Sep;9(9):1849-65. doi: 10.1074/mcp.M110.000406. Epub 2010 May 10.


Cytokine-associated drug toxicity in human hepatocytes is associated with signaling network dysregulation.

Cosgrove BD, Alexopoulos LG, Hang TC, Hendriks BS, Sorger PK, Griffith LG, Lauffenburger DA.

Mol Biosyst. 2010 Jul;6(7):1195-206. doi: 10.1039/b926287c. Epub 2010 Apr 1.


A multipathway phosphoproteomic signaling network model of idiosyncratic drug- and inflammatory cytokine-induced toxicity in human hepatocytes.

Cosgrove BD, Alexopoulos LG, Saez-Rodriguez J, Griffith LG, Lauffenburger DA.

Conf Proc IEEE Eng Med Biol Soc. 2009;2009:5452-5. doi: 10.1109/IEMBS.2009.5334019.


A home away from home: challenges and opportunities in engineering in vitro muscle satellite cell niches.

Cosgrove BD, Sacco A, Gilbert PM, Blau HM.

Differentiation. 2009 Sep-Oct;78(2-3):185-94. doi: 10.1016/j.diff.2009.08.004. Review.


Microfluidic concentration-enhanced cellular kinase activity assay.

Lee JH, Cosgrove BD, Lauffenburger DA, Han J.

J Am Chem Soc. 2009 Aug 5;131(30):10340-1. doi: 10.1021/ja902594f.


Three-kinase inhibitor combination recreates multipathway effects of a geldanamycin analogue on hepatocellular carcinoma cell death.

Pritchard JR, Cosgrove BD, Hemann MT, Griffith LG, Wands JR, Lauffenburger DA.

Mol Cancer Ther. 2009 Aug;8(8):2183-92. doi: 10.1158/1535-7163.MCT-08-1203. Epub 2009 Aug 11.


Synergistic drug-cytokine induction of hepatocellular death as an in vitro approach for the study of inflammation-associated idiosyncratic drug hepatotoxicity.

Cosgrove BD, King BM, Hasan MA, Alexopoulos LG, Farazi PA, Hendriks BS, Griffith LG, Sorger PK, Tidor B, Xu JJ, Lauffenburger DA.

Toxicol Appl Pharmacol. 2009 Jun 15;237(3):317-30. doi: 10.1016/j.taap.2009.04.002. Epub 2009 Apr 9.


An inducible autocrine cascade regulates rat hepatocyte proliferation and apoptosis responses to tumor necrosis factor-alpha.

Cosgrove BD, Cheng C, Pritchard JR, Stolz DB, Lauffenburger DA, Griffith LG.

Hepatology. 2008 Jul;48(1):276-88. doi: 10.1002/hep.22335.


"I have multiple sclerosis".

Cosgrove BD.

RN. 1966 Jul;29(7):35-9. No abstract available.


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