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Items: 38


An Mtb-Human Protein-Protein Interaction Map Identifies a Switch between Host Antiviral and Antibacterial Responses.

Penn BH, Netter Z, Johnson JR, Von Dollen J, Jang GM, Johnson T, Ohol YM, Maher C, Bell SL, Geiger K, Golovkine G, Du X, Choi A, Parry T, Mohapatra BC, Storck MD, Band H, Chen C, Jäger S, Shales M, Portnoy DA, Hernandez R, Coscoy L, Cox JS, Krogan NJ.

Mol Cell. 2018 Aug 16;71(4):637-648.e5. doi: 10.1016/j.molcel.2018.07.010.


A Kaposi's Sarcoma-Associated Herpesvirus Infection Mechanism Is Independent of Integrins α3β1, αVβ3, and αVβ5.

TerBush AA, Hafkamp F, Lee HJ, Coscoy L.

J Virol. 2018 Aug 16;92(17). pii: e00803-18. doi: 10.1128/JVI.00803-18. Print 2018 Sep 1.


Induction of necroptotic cell death by viral activation of the RIG-I or STING pathway.

Schock SN, Chandra NV, Sun Y, Irie T, Kitagawa Y, Gotoh B, Coscoy L, Winoto A.

Cell Death Differ. 2017 Apr;24(4):615-625. doi: 10.1038/cdd.2016.153. Epub 2017 Jan 6.


A Herpesviral induction of RAE-1 NKG2D ligand expression occurs through release of HDAC mediated repression.

Greene TT, Tokuyama M, Knudsen GM, Kunz M, Lin J, Greninger AL, DeFilippis VR, DeRisi JL, Raulet DH, Coscoy L.

Elife. 2016 Nov 22;5. pii: e14749. doi: 10.7554/eLife.14749.


A forward genetic screen reveals novel independent regulators of ULBP1, an activating ligand for natural killer cells.

Gowen BG, Chim B, Marceau CD, Greene TT, Burr P, Gonzalez JR, Hesser CR, Dietzen PA, Russell T, Iannello A, Coscoy L, Sentman CL, Carette JE, Muljo SA, Raulet DH.

Elife. 2015 Nov 13;4. pii: e08474. doi: 10.7554/eLife.08474.


Gammaherpesviral gene expression and virion composition are broadly controlled by accelerated mRNA degradation.

Abernathy E, Clyde K, Yeasmin R, Krug LT, Burlingame A, Coscoy L, Glaunsinger B.

PLoS Pathog. 2014 Jan;10(1):e1003882. doi: 10.1371/journal.ppat.1003882. Epub 2014 Jan 16.


A role for host activation-induced cytidine deaminase in innate immune defense against KSHV.

Bekerman E, Jeon D, Ardolino M, Coscoy L.

PLoS Pathog. 2013;9(11):e1003748. doi: 10.1371/journal.ppat.1003748. Epub 2013 Nov 7.


A Novel Peptide-Based SILAC Method to Identify the Posttranslational Modifications Provides Evidence for Unconventional Ubiquitination in the ER-Associated Degradation Pathway.

Anania VG, Bustos DJ, Lill JR, Kirkpatrick DS, Coscoy L.

Int J Proteomics. 2013;2013:857918. doi: 10.1155/2013/857918. Epub 2013 Feb 3.


Virally-induced upregulation of heparan sulfate on B cells via the action of type I IFN.

Jarousse N, Trujillo DL, Wilcox-Adelman S, Coscoy L.

J Immunol. 2011 Dec 1;187(11):5540-7. doi: 10.4049/jimmunol.1003495. Epub 2011 Nov 2.


Expression of the RAE-1 family of stimulatory NK-cell ligands requires activation of the PI3K pathway during viral infection and transformation.

Tokuyama M, Lorin C, Delebecque F, Jung H, Raulet DH, Coscoy L.

PLoS Pathog. 2011 Sep;7(9):e1002265. doi: 10.1371/journal.ppat.1002265. Epub 2011 Sep 22.


Global mRNA degradation during lytic gammaherpesvirus infection contributes to establishment of viral latency.

Richner JM, Clyde K, Pezda AC, Cheng BY, Wang T, Kumar GR, Covarrubias S, Coscoy L, Glaunsinger B.

PLoS Pathog. 2011 Jul;7(7):e1002150. doi: 10.1371/journal.ppat.1002150. Epub 2011 Jul 21.


Suppression of TLR9 immunostimulatory motifs in the genome of a gammaherpesvirus.

Pezda AC, Penn A, Barton GM, Coscoy L.

J Immunol. 2011 Jul 15;187(2):887-96. doi: 10.4049/jimmunol.1003737. Epub 2011 Jun 10.


Fas-associated death domain (FADD) and the E3 ubiquitin-protein ligase TRIM21 interact to negatively regulate virus-induced interferon production.

Young JA, Sermwittayawong D, Kim HJ, Nandu S, An N, Erdjument-Bromage H, Tempst P, Coscoy L, Winoto A.

J Biol Chem. 2011 Feb 25;286(8):6521-31. doi: 10.1074/jbc.M110.172288. Epub 2010 Dec 23.


Palmitoylation of MIR2 is required for its function.

Anania VG, Coscoy L.

J Virol. 2011 Mar;85(5):2288-95. doi: 10.1128/JVI.01961-10. Epub 2010 Dec 15.


Stress-regulated targeting of the NKG2D ligand Mult1 by a membrane-associated RING-CH family E3 ligase.

Nice TJ, Deng W, Coscoy L, Raulet DH.

J Immunol. 2010 Nov 1;185(9):5369-76. doi: 10.4049/jimmunol.1000247. Epub 2010 Sep 24.


The U24 protein from human herpesvirus 6 and 7 affects endocytic recycling.

Sullivan BM, Coscoy L.

J Virol. 2010 Feb;84(3):1265-75. doi: 10.1128/JVI.01775-09. Epub 2009 Nov 18.


Posttranslational regulation of the NKG2D ligand Mult1 in response to cell stress.

Nice TJ, Coscoy L, Raulet DH.

J Exp Med. 2009 Feb 16;206(2):287-98. doi: 10.1084/jem.20081335. Epub 2009 Jan 26.


Lack of heparan sulfate expression in B-cell lines: implications for Kaposi's sarcoma-associated herpesvirus and murine gammaherpesvirus 68 infections.

Jarousse N, Chandran B, Coscoy L.

J Virol. 2008 Dec;82(24):12591-7. doi: 10.1128/JVI.01167-08. Epub 2008 Oct 8.


Selection of mutant CHO clones resistant to murine gammaherpesvirus 68 infection.

Jarousse N, Coscoy L.

Virology. 2008 Apr 10;373(2):376-86. doi: 10.1016/j.virol.2007.12.004. Epub 2008 Jan 14.


DNA mismanagement leads to immune system oversight.

Coscoy L, Raulet DH.

Cell. 2007 Nov 30;131(5):836-8.


Immune evasion by Kaposi's sarcoma-associated herpesvirus.

Coscoy L.

Nat Rev Immunol. 2007 May;7(5):391-401. Review.


Ubiquitination on nonlysine residues by a viral E3 ubiquitin ligase.

Cadwell K, Coscoy L.

Science. 2005 Jul 1;309(5731):127-30. Erratum in: Science. 2006 Jan 13;311(5758):177.


PHD domains and E3 ubiquitin ligases: viruses make the connection.

Coscoy L, Ganem D.

Trends Cell Biol. 2003 Jan;13(1):7-12. Review.


Microarray-based detection and genotyping of viral pathogens.

Wang D, Coscoy L, Zylberberg M, Avila PC, Boushey HA, Ganem D, DeRisi JL.

Proc Natl Acad Sci U S A. 2002 Nov 26;99(24):15687-92. Epub 2002 Nov 12.


Functional organization of MIR2, a novel viral regulator of selective endocytosis.

Sanchez DJ, Coscoy L, Ganem D.

J Biol Chem. 2002 Feb 22;277(8):6124-30. Epub 2001 Dec 18.


Kaposi's sarcoma-associated herpesvirus encodes two proteins that block cell surface display of MHC class I chains by enhancing their endocytosis.

Coscoy L, Ganem D.

Proc Natl Acad Sci U S A. 2000 Jul 5;97(14):8051-6. Erratum in: Proc Natl Acad Sci U S A 2001 Feb 13;98(4):2111.


Molecular mechanism of tumorigenesis in mice transgenic for the human T cell leukemia virus Tax gene.

Coscoy L, Gonzalez-Dunia D, Tangy F, Syan S, Brahic M, Ozden S.

Virology. 1998 Sep 1;248(2):332-41.


Infection of choroid plexus cells by human T cell leukaemia virus type I.

Coscoy L, Gonzalez-Dunia D, Brahic M, Ozden S.

J Gen Virol. 1997 Jan;78 ( Pt 1):143-6.


Analysis of the expression directed by two HTLV-I promoters in transgenic mice.

Coscoy L, Gonzalez-Dunia D, Chirinian-Swan S, Brahic M, Ozden S.

J Neurovirol. 1996 Oct;2(5):336-44.


HTLV-I transgenic models: an overview.

Ozden S, Coscoy L, Gonzalez-Dunia D.

J Acquir Immune Defic Syndr Hum Retrovirol. 1996;13 Suppl 1:S154-61. Review.


A search for human T-cell leukemia virus type I in the lesions of patients with tropical spastic paraparesis and polymyositis.

Tangy F, Vernant JC, Coscoy L, Ossondo M, Bellance R, Zaninovic V, Cartier L, Brahic M, Ozden S.

Ann Neurol. 1995 Sep;38(3):454-60.


Localization and biochemical characterization of alfalfa mosaic virus replication complexes.

De Graaff M, Coscoy L, Jaspars EM.

Virology. 1993 Jun;194(2):878-81.


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