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Items: 16


Disease-associated missense mutations in the EVH1 domain disrupt intrinsic WASp function causing dysregulated actin dynamics and impaired dendritic cell migration.

Worth AJ, Metelo J, Bouma G, Moulding D, Fritzsche M, Vernay B, Charras G, Cory GO, Thrasher AJ, Burns SO.

Blood. 2013 Jan 3;121(1):72-84. doi: 10.1182/blood-2012-01-403857. Epub 2012 Nov 15.


Tyrosine phosphorylation of WASP promotes calpain-mediated podosome disassembly.

Macpherson L, Monypenny J, Blundell MP, Cory GO, Tomé-García J, Thrasher AJ, Jones GE, Calle Y.

Haematologica. 2012 May;97(5):687-91. doi: 10.3324/haematol.2011.048868. Epub 2011 Dec 1.


Phosphorylation of WASp is a key regulator of activity and stability in vivo.

Blundell MP, Bouma G, Metelo J, Worth A, Calle Y, Cowell LA, Westerberg LS, Moulding DA, Mirando S, Kinnon C, Cory GO, Jones GE, Snapper SB, Burns SO, Thrasher AJ.

Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15738-43. doi: 10.1073/pnas.0904346106. Epub 2009 Sep 1.


WAVE2 is regulated by multiple phosphorylation events within its VCA domain.

Pocha SM, Cory GO.

Cell Motil Cytoskeleton. 2009 Jan;66(1):36-47. doi: 10.1002/cm.20323.


Phosphorylation of WAVE2 by MAP kinases regulates persistent cell migration and polarity.

Danson CM, Pocha SM, Bloomberg GB, Cory GO.

J Cell Sci. 2007 Dec 1;120(Pt 23):4144-54.


Unregulated actin polymerization by WASp causes defects of mitosis and cytokinesis in X-linked neutropenia.

Moulding DA, Blundell MP, Spiller DG, White MR, Cory GO, Calle Y, Kempski H, Sinclair J, Ancliff PJ, Kinnon C, Jones GE, Thrasher AJ.

J Exp Med. 2007 Sep 3;204(9):2213-24. Epub 2007 Aug 27.


Membrane curvature: the power of bananas, zeppelins and boomerangs.

Cory GO, Cullen PJ.

Curr Biol. 2007 Jun 19;17(12):R455-7.


Two novel activating mutations in the Wiskott-Aldrich syndrome protein result in congenital neutropenia.

Ancliff PJ, Blundell MP, Cory GO, Calle Y, Worth A, Kempski H, Burns S, Jones GE, Sinclair J, Kinnon C, Hann IM, Gale RE, Linch DC, Thrasher AJ.

Blood. 2006 Oct 1;108(7):2182-9. Epub 2006 Jun 27.


Mechanisms of WASp-mediated hematologic and immunologic disease.

Burns S, Cory GO, Vainchenker W, Thrasher AJ.

Blood. 2004 Dec 1;104(12):3454-62. Epub 2004 Aug 12. Review.


Cell motility: braking WAVEs.

Cory GO, Ridley AJ.

Nature. 2002 Aug 15;418(6899):732-3. No abstract available. Erratum in: Nature 2002 Sep 26;419(6905):354.


The SH3 domain of Bruton's tyrosine kinase displays altered ligand binding properties when auto-phosphorylated in vitro.

Morrogh LM, Hinshelwood S, Costello P, Cory GO, Kinnon C.

Eur J Immunol. 1999 Jul;29(7):2269-79.


The identification of Bruton's tyrosine kinase and Wiskott-Aldrich syndrome protein associated proteins and signalling pathways.

Kinnon C, Cory GO, MacCarthy-Morrogh L, Banin S, Gout I, Lovering RC, Brickell PM.

Biochem Soc Trans. 1997 May;25(2):648-50. Review. No abstract available.


Evidence that the Wiskott-Aldrich syndrome protein may be involved in lymphoid cell signaling pathways.

Cory GO, MacCarthy-Morrogh L, Banin S, Gout I, Brickell PM, Levinsky RJ, Kinnon C, Lovering RC.

J Immunol. 1996 Nov 1;157(9):3791-5.


The protein product of the c-cbl protooncogene is phosphorylated after B cell receptor stimulation and binds the SH3 domain of Bruton's tyrosine kinase.

Cory GO, Lovering RC, Hinshelwood S, MacCarthy-Morrogh L, Levinsky RJ, Kinnon C.

J Exp Med. 1995 Aug 1;182(2):611-5.

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