1.

Genetic variation in CFTR and modifier loci may modulate cystic fibrosis disease severity.

Paranjapye A, Ruffin M, Harris A, Corvol H.

J Cyst Fibros. 2019 Nov 13. pii: S1569-1993(19)30963-4. doi: 10.1016/j.jcf.2019.11.001. [Epub ahead of print]

PMID:
31734115
2.

Genetic modifiers of cystic fibrosis-related diabetes have extensive overlap with type 2 diabetes and related traits.

Aksit MA, Pace RG, Vecchio-Pagan B, Ling H, Rommens JM, Boelle PY, Guillot L, Raraigh KS, Pugh E, Zhang P, Strug LJ, Drumm ML, Knowles MR, Cutting GR, Corvol H, Blackman SM.

J Clin Endocrinol Metab. 2019 Oct 19. pii: dgz102. doi: 10.1210/clinem/dgz102. [Epub ahead of print]

PMID:
31697830
3.

Respiratory Epithelial Cells Can Remember Infection: A Proof of Concept Study.

Bigot J, Guillot L, Guitard J, Ruffin M, Corvol H, Chignard M, Hennequin C, Balloy V.

J Infect Dis. 2019 Nov 3. pii: jiz569. doi: 10.1093/infdis/jiz569. [Epub ahead of print]

PMID:
31678998
4.

Real-Life Safety and Effectiveness of Lumacaftor-Ivacaftor in Patients with Cystic Fibrosis.

Burgel PR, Munck A, Durieu I, Chiron R, Mely L, Prevotat A, Murris-Espin M, Porzio M, Abely M, Reix P, Marguet C, Macey J, Sermet-Gaudelus I, Corvol H, Bui S, Lemonnier L, Dehilotte C, Da Silva J, Paillasseur JL, Hubert D; French Cystic Fibrosis Reference Network study group.

Am J Respir Crit Care Med. 2019 Oct 11. doi: 10.1164/rccm.201906-1227OC. [Epub ahead of print]

PMID:
31601120
5.

Genetic association and transcriptome integration identify contributing genes and tissues at cystic fibrosis modifier loci.

Gong J, Wang F, Xiao B, Panjwani N, Lin F, Keenan K, Avolio J, Esmaeili M, Zhang L, He G, Soave D, Mastromatteo S, Baskurt Z, Kim S, O'Neal WK, Polineni D, Blackman SM, Corvol H, Cutting GR, Drumm M, Knowles MR, Rommens JM, Sun L, Strug LJ.

PLoS Genet. 2019 Feb 26;15(2):e1008007. doi: 10.1371/journal.pgen.1008007. eCollection 2019 Feb.

6.

SERPINA1 Z allele is associated with cystic fibrosis liver disease.

Boëlle PY, Debray D, Guillot L, Corvol H; French CF Modifier Gene Study Investigators.

Genet Med. 2019 Sep;21(9):2151-2155. doi: 10.1038/s41436-019-0449-6. Epub 2019 Feb 11.

PMID:
30739910
7.

Modifier genes in cystic fibrosis-related liver disease.

Debray D, Corvol H, Housset C.

Curr Opin Gastroenterol. 2019 Mar;35(2):88-92. doi: 10.1097/MOG.0000000000000508.

8.

CHAC1 Is Differentially Expressed in Normal and Cystic Fibrosis Bronchial Epithelial Cells and Regulates the Inflammatory Response Induced by Pseudomonas aeruginosa.

Perra L, Balloy V, Foussignière T, Moissenet D, Petat H, Mungrue IN, Touqui L, Corvol H, Chignard M, Guillot L.

Front Immunol. 2018 Nov 29;9:2823. doi: 10.3389/fimmu.2018.02823. eCollection 2018.

9.

Human Bronchial Epithelial Cells Inhibit Aspergillus fumigatus Germination of Extracellular Conidia via FleA Recognition.

Richard N, Marti L, Varrot A, Guillot L, Guitard J, Hennequin C, Imberty A, Corvol H, Chignard M, Balloy V.

Sci Rep. 2018 Oct 24;8(1):15699. doi: 10.1038/s41598-018-33902-0.

10.

Emerging microRNA Therapeutic Approaches for Cystic Fibrosis.

Bardin P, Sonneville F, Corvol H, Tabary O.

Front Pharmacol. 2018 Oct 8;9:1113. doi: 10.3389/fphar.2018.01113. eCollection 2018. Review.

11.

SLC26A9 Gene Is Associated With Lung Function Response to Ivacaftor in Patients With Cystic Fibrosis.

Corvol H, Mésinèle J, Douksieh IH, Strug LJ, Boëlle PY, Guillot L.

Front Pharmacol. 2018 Jul 26;9:828. doi: 10.3389/fphar.2018.00828. eCollection 2018.

12.

Cystic Fibrosis Liver Disease: Outcomes and Risk Factors in a Large Cohort of French Patients.

Boëlle PY, Debray D, Guillot L, Clement A, Corvol H; French CF Modifier Gene Study Investigators.

Hepatology. 2019 Apr;69(4):1648-1656. doi: 10.1002/hep.30148. Epub 2018 Dec 28.

13.

AGTR2 absence or antagonism prevents cystic fibrosis pulmonary manifestations.

Darrah RJ, Jacono FJ, Joshi N, Mitchell AL, Sattar A, Campanaro CK, Litman P, Frey J, Nethery DE, Barbato ES, Hodges CA, Corvol H, Cutting GR, Knowles MR, Strug LJ, Drumm ML.

J Cyst Fibros. 2019 Jan;18(1):127-134. doi: 10.1016/j.jcf.2018.05.013. Epub 2018 Jun 22.

14.

Opposite Expression of Hepatic and Pulmonary Corticosteroid-Binding Globulin in Cystic Fibrosis Patients.

Tchoukaev A, Taytard J, Rousselet N, Rebeyrol C, Debray D, Blouquit-Laye S, Moisan MP, Foury A, Guillot L, Corvol H, Tabary O, Le Rouzic P.

Front Pharmacol. 2018 Jun 5;9:545. doi: 10.3389/fphar.2018.00545. eCollection 2018.

15.

Small RNA and transcriptome sequencing reveal the role of miR-199a-3p in inflammatory processes in cystic fibrosis airways.

Bardin P, Marchal-Duval E, Sonneville F, Blouquit-Laye S, Rousselet N, Le Rouzic P, Corvol H, Tabary O.

J Pathol. 2018 Aug;245(4):410-420. doi: 10.1002/path.5095. Epub 2018 Jun 20.

PMID:
29732561
16.

Pulmonary hemosiderosis in children with Down syndrome: a national experience.

Alimi A, Taytard J, Abou Taam R, Houdouin V, Forgeron A, Lubrano Lavadera M, Cros P, Gibertini I, Derelle J, Deschildre A, Thumerelle C, Epaud R, Reix P, Fayon M, Roullaud S, Troussier F, Renoux MC, de Blic J, Leyronnas S, Thouvenin G, Perisson C, Ravel A, Clement A, Corvol H, Nathan N; French RespiRare® group.

Orphanet J Rare Dis. 2018 Apr 20;13(1):60. doi: 10.1186/s13023-018-0806-6.

17.

Improving imputation in disease-relevant regions: lessons from cystic fibrosis.

Panjwani N, Xiao B, Xu L, Gong J, Keenan K, Lin F, He G, Baskurt Z, Kim S, Zhang L, Esmaeili M, Blackman S, Scherer SW, Corvol H, Drumm M, Knowles M, Cutting G, Rommens JM, Sun L, Strug LJ.

NPJ Genom Med. 2018 Mar 20;3:8. doi: 10.1038/s41525-018-0047-6. eCollection 2018.

18.

Whole exome sequencing in three families segregating a pediatric case of sarcoidosis.

Calender A, Rollat Farnier PA, Buisson A, Pinson S, Bentaher A, Lebecque S, Corvol H, Abou Taam R, Houdouin V, Bardel C, Roy P, Devouassoux G, Cottin V, Seve P, Bernaudin JF, Lim CX, Weichhart T, Valeyre D, Pacheco Y, Clement A, Nathan N; in the frame of GSF (Groupe Sarcoïdose France).

BMC Med Genomics. 2018 Mar 6;11(1):23. doi: 10.1186/s12920-018-0338-x.

19.

Gas exchanges in children with cystic fibrosis or primary ciliary dyskinesia: A retrospective study.

Fuger M, Aupiais C, Thouvenin G, Taytard J, Tamalet A, Escudier E, Boizeau P, Corvol H, Beydon N.

Respir Physiol Neurobiol. 2018 May;251:1-7. doi: 10.1016/j.resp.2018.01.010. Epub 2018 Jan 31.

20.

Stenotrophomonas maltophilia: A marker of lung disease severity.

Berdah L, Taytard J, Leyronnas S, Clement A, Boelle PY, Corvol H.

Pediatr Pulmonol. 2018 Apr;53(4):426-430. doi: 10.1002/ppul.23943. Epub 2018 Jan 4.

21.

FAM13A is a modifier gene of cystic fibrosis lung phenotype regulating rhoa activity, actin cytoskeleton dynamics and epithelial-mesenchymal transition.

Corvol H, Rousselet N, Thompson KE, Berdah L, Cottin G, Foussigniere T, Longchampt E, Fiette L, Sage E, Prunier C, Drumm M, Hodges CA, Boëlle PY, Guillot L.

J Cyst Fibros. 2018 Mar;17(2):190-203. doi: 10.1016/j.jcf.2017.11.003. Epub 2017 Nov 26.

22.

Omalizumab treatment for allergic bronchopulmonary aspergillosis in young patients with cystic fibrosis.

Perisson C, Destruys L, Grenet D, Bassinet L, Derelle J, Sermet-Gaudelus I, Thumerelle C, Prevotat A, Rosner V, Clement A, Corvol H.

Respir Med. 2017 Dec;133:12-15. doi: 10.1016/j.rmed.2017.11.007. Epub 2017 Nov 10.

PMID:
29173443
23.

MicroRNA-9 downregulates the ANO1 chloride channel and contributes to cystic fibrosis lung pathology.

Sonneville F, Ruffin M, Coraux C, Rousselet N, Le Rouzic P, Blouquit-Laye S, Corvol H, Tabary O.

Nat Commun. 2017 Sep 27;8(1):710. doi: 10.1038/s41467-017-00813-z.

24.

Airway Mucosal Host Defense Is Key to Genomic Regulation of Cystic Fibrosis Lung Disease Severity.

Polineni D, Dang H, Gallins PJ, Jones LC, Pace RG, Stonebraker JR, Commander LA, Krenicky JE, Zhou YH, Corvol H, Cutting GR, Drumm ML, Strug LJ, Boyle MP, Durie PR, Chmiel JF, Zou F, Wright FA, O'Neal WK, Knowles MR.

Am J Respir Crit Care Med. 2018 Jan 1;197(1):79-93. doi: 10.1164/rccm.201701-0134OC.

25.

Corrigendum: Novel variation at chr11p13 associated with cystic fibrosis lung disease severity.

Dang H, Gallins PJ, Pace RG, Guo XL, Stonebraker JR, Corvol H, Cutting GR, Drumm ML, Strug LJ, Knowles MR, O'Neal WK.

Hum Genome Var. 2017 May 25;4:17016. doi: 10.1038/hgv.2017.16. eCollection 2017.

26.

Bronchial Epithelial Cells from Cystic Fibrosis Patients Express a Specific Long Non-coding RNA Signature upon Pseudomonas aeruginosa Infection.

Balloy V, Koshy R, Perra L, Corvol H, Chignard M, Guillot L, Scaria V.

Front Cell Infect Microbiol. 2017 May 29;7:218. doi: 10.3389/fcimb.2017.00218. eCollection 2017.

27.

DNA methylation at modifier genes of lung disease severity is altered in cystic fibrosis.

Magalhães M, Rivals I, Claustres M, Varilh J, Thomasset M, Bergougnoux A, Mely L, Leroy S, Corvol H, Guillot L, Murris M, Beyne E, Caimmi D, Vachier I, Chiron R, De Sario A.

Clin Epigenetics. 2017 Feb 14;9:19. doi: 10.1186/s13148-016-0300-8. eCollection 2017.

28.

[New therapeutic developments in cystic fibrosis].

Bui S, Macey J, Fayon M; « nouvelles thérapeutiques de la Société Française pour la Mucoviscidose », Bihouée T, Burgel PR, Colomb V, Corvol H, Durieu I, Hubert D, Marguet C, Mas E, Munck A, Murris-Espin M, Reix P, Sermet-Gaudelus I.

Arch Pediatr. 2016 Dec;23(12S):12S47-12S53. doi: 10.1016/S0929-693X(17)30062-3. Review. French.

PMID:
28231894
29.

Cystic fibrosis gene modifier SLC26A9 modulates airway response to CFTR-directed therapeutics.

Strug LJ, Gonska T, He G, Keenan K, Ip W, Boëlle PY, Lin F, Panjwani N, Gong J, Li W, Soave D, Xiao B, Tullis E, Rabin H, Parkins MD, Price A, Zuberbuhler PC, Corvol H, Ratjen F, Sun L, Bear CE, Rommens JM.

Hum Mol Genet. 2016 Oct 15;25(20):4590-4600. doi: 10.1093/hmg/ddw290.

30.

Surfactant protein A: A key player in lung homeostasis.

Nathan N, Taytard J, Duquesnoy P, Thouvenin G, Corvol H, Amselem S, Clement A.

Int J Biochem Cell Biol. 2016 Dec;81(Pt A):151-155. doi: 10.1016/j.biocel.2016.11.003. Epub 2016 Nov 9. Review.

PMID:
27836807
31.

Long-term effects of azithromycin in patients with cystic fibrosis.

Samson C, Tamalet A, Thien HV, Taytard J, Perisson C, Nathan N, Clement A, Boelle PY, Corvol H.

Respir Med. 2016 Aug;117:1-6. doi: 10.1016/j.rmed.2016.05.025. Epub 2016 May 24.

32.

Are CF carriers predisposed to asthma?

Corvol H, Guillot L.

J Cyst Fibros. 2016 Sep;15(5):555-6. doi: 10.1016/j.jcf.2016.07.003. Epub 2016 Jul 20. No abstract available.

33.

Novel variation at chr11p13 associated with cystic fibrosis lung disease severity.

Dang H, Gallins PJ, Pace RG, Guo XL, Stonebraker JR, Corvol H, Cutting GR, Drumm ML, Strug LJ, Knowles MR, O'Neal WK.

Hum Genome Var. 2016 Jul 7;3:16020. doi: 10.1038/hgv.2016.20. eCollection 2016. Erratum in: Hum Genome Var. 2017 May 25;4:17016.

34.

Sources of Variation in Sweat Chloride Measurements in Cystic Fibrosis.

Collaco JM, Blackman SM, Raraigh KS, Corvol H, Rommens JM, Pace RG, Boelle PY, McGready J, Sosnay PR, Strug LJ, Knowles MR, Cutting GR.

Am J Respir Crit Care Med. 2016 Dec 1;194(11):1375-1382.

35.

Erratum à l'article « Nouvelles thérapeutiques de la mucoviscidose ciblant le gène ou la protéine CFTR » [Rev. Mal. Respir. (2016). doi: 10.1016/j.rmr.2015.11.010].

Hubert D, Bui S, Marguet C, Colomb-Jung V, Murris-Espin M, Corvol H, Munck A.

Rev Mal Respir. 2016 Jun;33(6):558. doi: 10.1016/j.rmr.2016.02.005. Epub 2016 Apr 23. French. No abstract available.

PMID:
27117927
36.

Features of Severe Liver Disease With Portal Hypertension in Patients With Cystic Fibrosis.

Stonebraker JR, Ooi CY, Pace RG, Corvol H, Knowles MR, Durie PR, Ling SC.

Clin Gastroenterol Hepatol. 2016 Aug;14(8):1207-1215.e3. doi: 10.1016/j.cgh.2016.03.041. Epub 2016 Apr 5.

37.

Ultrasonography and Computed Tomographic Manifestations of Abdominal Sarcoidosis in Children.

Morel B, Sileo C, Epaud R, Blondiaux E, Nathan N, Corvol H, Tounian P, Le Pointe HD.

J Pediatr Gastroenterol Nutr. 2016 Aug;63(2):195-9. doi: 10.1097/MPG.0000000000001175.

PMID:
26913758
38.

Lessons from a French collaborative case-control study in cystic fibrosis patients during the 2009 A/H1N1 influenza pandemy.

Bucher J, Boelle PY, Hubert D, Lebourgeois M, Stremler N, Durieu I, Bremont F, Deneuville E, Delaisi B, Corvol H, Bassinet L, Grenet D, Remus N, Vodoff MV, Boussaud V, Troussier F, Leruez-Ville M, Treluyer JM, Launay O, Sermet-Gaudelus I.

BMC Infect Dis. 2016 Feb 1;16:55. doi: 10.1186/s12879-016-1352-2.

39.

[New therapies for cystic fibrosis targeting the CFTR gene or the CFTR protein].

Hubert D, Bui S, Marguet C, Colomb-Jung V, Murris-Espin M, Corvol H, Munck A.

Rev Mal Respir. 2016 Oct;33(8):658-665. doi: 10.1016/j.rmr.2015.11.010. Epub 2016 Jan 21. Review. French.

PMID:
26806675
40.

Normal and Cystic Fibrosis Human Bronchial Epithelial Cells Infected with Pseudomonas aeruginosa Exhibit Distinct Gene Activation Patterns.

Balloy V, Varet H, Dillies MA, Proux C, Jagla B, Coppée JY, Tabary O, Corvol H, Chignard M, Guillot L.

PLoS One. 2015 Oct 20;10(10):e0140979. doi: 10.1371/journal.pone.0140979. eCollection 2015.

41.

Genome-wide association meta-analysis identifies five modifier loci of lung disease severity in cystic fibrosis.

Corvol H, Blackman SM, Boëlle PY, Gallins PJ, Pace RG, Stonebraker JR, Accurso FJ, Clement A, Collaco JM, Dang H, Dang AT, Franca A, Gong J, Guillot L, Keenan K, Li W, Lin F, Patrone MV, Raraigh KS, Sun L, Zhou YH, O'Neal WK, Sontag MK, Levy H, Durie PR, Rommens JM, Drumm ML, Wright FA, Strug LJ, Cutting GR, Knowles MR.

Nat Commun. 2015 Sep 29;6:8382. doi: 10.1038/ncomms9382.

42.

A Joint Location-Scale Test Improves Power to Detect Associated SNPs, Gene Sets, and Pathways.

Soave D, Corvol H, Panjwani N, Gong J, Li W, Boëlle PY, Durie PR, Paterson AD, Rommens JM, Strug LJ, Sun L.

Am J Hum Genet. 2015 Jul 2;97(1):125-38. doi: 10.1016/j.ajhg.2015.05.015.

43.

Sweat test practice in pediatric pulmonology after introduction of cystic fibrosis newborn screening.

Grimaldi C, Brémont F, Berlioz-Baudoin M, Brouard J, Corvol H, Couderc L, Lezmi G, Pin I, Petit I, Reix P, Remus N, Schweitzer C, Thumerelle C, Dubus JC.

Eur J Pediatr. 2015 Dec;174(12):1613-20. doi: 10.1007/s00431-015-2579-4. Epub 2015 Jun 16.

PMID:
26074372
44.

RSPH3 Mutations Cause Primary Ciliary Dyskinesia with Central-Complex Defects and a Near Absence of Radial Spokes.

Jeanson L, Copin B, Papon JF, Dastot-Le Moal F, Duquesnoy P, Montantin G, Cadranel J, Corvol H, Coste A, Désir J, Souayah A, Kott E, Collot N, Tissier S, Louis B, Tamalet A, de Blic J, Clement A, Escudier E, Amselem S, Legendre M.

Am J Hum Genet. 2015 Jul 2;97(1):153-62. doi: 10.1016/j.ajhg.2015.05.004. Epub 2015 Jun 11.

45.

Biomarkers in Interstitial lung diseases.

Nathan N, Corvol H, Amselem S, Clement A.

Paediatr Respir Rev. 2015 Sep;16(4):219-24. doi: 10.1016/j.prrv.2015.05.002. Epub 2015 May 12. Review.

PMID:
26027849
46.

[Challenges of personalized medicine for cystic fibrosis].

Corvol H, Taytard J, Tabary O, Le Rouzic P, Guillot L, Clement A.

Arch Pediatr. 2015 Jul;22(7):778-86. doi: 10.1016/j.arcped.2015.04.015. Epub 2015 May 26. French.

PMID:
26021452
47.

Vaccine coverage in CF children: A French multicenter study.

Masson A, Launay O, Delaisi B, Bassinet L, Remus N, Lebourgeois M, Chedevergne F, Bailly C, Foucaud P, Corvol H, deBlic J, Sermet-Gaudelus I.

J Cyst Fibros. 2015 Sep;14(5):615-20. doi: 10.1016/j.jcf.2015.04.006. Epub 2015 May 16.

48.

Translating the genetics of cystic fibrosis to personalized medicine.

Corvol H, Thompson KE, Tabary O, le Rouzic P, Guillot L.

Transl Res. 2016 Feb;168:40-49. doi: 10.1016/j.trsl.2015.04.008. Epub 2015 Apr 15. Review.

PMID:
25940043
49.

Lung sarcoidosis in children: update on disease expression and management.

Nathan N, Marcelo P, Houdouin V, Epaud R, de Blic J, Valeyre D, Houzel A, Busson PF, Corvol H, Deschildre A, Clement A; RespiRare and the French Sarcoidosis groups.

Thorax. 2015 Jun;70(6):537-42. doi: 10.1136/thoraxjnl-2015-206825. Epub 2015 Apr 8.

PMID:
25855608
50.

Variants in Solute Carrier SLC26A9 Modify Prenatal Exocrine Pancreatic Damage in Cystic Fibrosis.

Miller MR, Soave D, Li W, Gong J, Pace RG, Boëlle PY, Cutting GR, Drumm ML, Knowles MR, Sun L, Rommens JM, Accurso F, Durie PR, Corvol H, Levy H, Sontag MK, Strug LJ.

J Pediatr. 2015 May;166(5):1152-1157.e6. doi: 10.1016/j.jpeds.2015.01.044. Epub 2015 Mar 11.

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