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Items: 1 to 50 of 87

1.

High Proportion of Potential Candidates for Immunotherapy in a Chilean Cohort of Gastric Cancer Patients: Results of the FORCE1 Study.

Cordova-Delgado M, Pinto MP, Retamal IN, Muñoz-Medel M, Bravo ML, Fernández MF, Cisternas B, Mondaca S, Sanchez C, Galindo H, Nervi B, Ibáñez C, Acevedo F, Madrid J, Peña J, Koch E, Maturana MJ, Romero D, de la Jara N, Torres J, Espinoza M, Balmaceda C, Liao Y, Li Z, Freire M, Gárate-Calderón V, Cáceres J, Sepúlveda-Hermosilla G, Lizana R, Ramos L, Artigas R, Norero E, Crovari F, Armisén R, Corvalán AH, Owen GI, Garrido M.

Cancers (Basel). 2019 Aug 30;11(9). pii: E1275. doi: 10.3390/cancers11091275.

2.

Fact or Fiction, It Is Time for a Verdict on Vasculogenic Mimicry?

Valdivia A, Mingo G, Aldana V, Pinto MP, Ramirez M, Retamal C, Gonzalez A, Nualart F, Corvalan AH, Owen GI.

Front Oncol. 2019 Aug 2;9:680. doi: 10.3389/fonc.2019.00680. eCollection 2019.

3.

A Novel Role for Helicobacter pylori Gamma-Glutamyltranspeptidase in Regulating Autophagy and Bacterial Internalization in Human Gastric Cells.

Bravo J, Díaz P, Corvalán AH, Quest AFG.

Cancers (Basel). 2019 Jun 10;11(6). pii: E801. doi: 10.3390/cancers11060801.

4.

The Reprimo gene family member, reprimo-like (rprml), is required for blood development in embryonic zebrafish.

Stanic K, Reig G, Wichmann IA, Opazo JC, Owen GI, Corvalán AH, Concha ML, Amigo JD.

Sci Rep. 2019 May 9;9(1):7131. doi: 10.1038/s41598-019-43436-8.

5.

The Phylogeographic Diversity of EBV and Admixed Ancestry in the Americas⁻Another Model of Disrupted Human-Pathogen Co-Evolution.

Corvalán AH, Ruedlinger J, de Mayo T, Polakovicova I, Gonzalez-Hormazabal P, Aguayo F.

Cancers (Basel). 2019 Feb 14;11(2). pii: E217. doi: 10.3390/cancers11020217. Review.

6.

Integrated Analysis of Mouse and Human Gastric Neoplasms Identifies Conserved microRNA Networks in Gastric Carcinogenesis.

Chen Z, Li Z, Soutto M, Wang W, Piazuelo MB, Zhu S, Guo Y, Maturana MJ, Corvalan AH, Chen X, Xu Z, El-Rifai WM.

Gastroenterology. 2019 Mar;156(4):1127-1139.e8. doi: 10.1053/j.gastro.2018.11.052. Epub 2018 Nov 28.

PMID:
30502323
7.

The Reprimo Gene Family: A Novel Gene Lineage in Gastric Cancer with Tumor Suppressive Properties.

Amigo JD, Opazo JC, Jorquera R, Wichmann IA, Garcia-Bloj BA, Alarcon MA, Owen GI, Corvalán AH.

Int J Mol Sci. 2018 Jun 25;19(7). pii: E1862. doi: 10.3390/ijms19071862. Review.

8.

[Cardiotoxicity of anticancer therapies. Towards the implementation of cardio-oncology units].

Hameau R, Gabrielli L, Garrido M, Guzmán AM, Retamal I, Vacarezza MJ, Greig D, Ocqueteau M, Sánchez C, Pizarro M, Corvalán A, Lavandero S, Castro PF, Martínez G.

Rev Med Chil. 2018 Jan;146(1):68-77. doi: 10.4067/s0034-98872018000100068. Review. Spanish.

9.

Role of microRNAs and Exosomes in Helicobacter pylori and Epstein-Barr Virus Associated Gastric Cancers.

Polakovicova I, Jerez S, Wichmann IA, Sandoval-Bórquez A, Carrasco-Véliz N, Corvalán AH.

Front Microbiol. 2018 Apr 5;9:636. doi: 10.3389/fmicb.2018.00636. eCollection 2018. Review.

10.

Chilean Gastric Cancer Task Force: A study protocol to obtain a clinical and molecular classification of a cohort of gastric cancer patients.

Owen GI, Pinto MP, Retamal IN, Fernádez MF, Cisternas B, Mondaca S, Sanchez C, Galindo H, Nervi B, Ibañez C, Acevedo F, Madrid J, Peña J, Bravo ML, Maturana MJ, Cordova-Delgado M, Romero D, de la Jara N, Torres J, Rodriguez-Fernandez M, Espinoza M, Balmaceda C, Freire M, Gárate-Calderón V, Crovari F, Jimenez-Fonseca P, Carmona-Bayonas A, Zwenger A, Armisen R, Corvalan AH, Garrido M.

Medicine (Baltimore). 2018 Apr;97(16):e0419. doi: 10.1097/MD.0000000000010419.

11.

Expression of RPRM/rprm in the Olfactory System of Embryonic Zebrafish (Danio rerio).

Stanic K, Quiroz A, Lemus CG, Wichmann IA, Corvalán AH, Owen GI, Opazo JC, Concha ML, Amigo JD.

Front Neuroanat. 2018 Mar 27;12:23. doi: 10.3389/fnana.2018.00023. eCollection 2018.

12.

Inverse expression of survivin and reprimo correlates with poor patient prognosis in gastric cancer.

Cerda-Opazo P, Valenzuela-Valderrama M, Wichmann I, Rodríguez A, Contreras-Reyes D, Fernández EA, Carrasco-Aviño G, Corvalán AH, Quest AFG.

Oncotarget. 2018 Feb 5;9(16):12853-12867. doi: 10.18632/oncotarget.24402. eCollection 2018 Feb 27.

13.

Differential expression profile of CXCR3 splicing variants is associated with thyroid neoplasia. Potential role in papillary thyroid carcinoma oncogenesis?

Urra S, Fischer MC, Martínez JR, Véliz L, Orellana P, Solar A, Bohmwald K, Kalergis A, Riedel C, Corvalán AH, Roa JC, Fuentealba R, Cáceres CJ, López-Lastra M, León A, Droppelmann N, González HE.

Oncotarget. 2017 Dec 20;9(2):2445-2467. doi: 10.18632/oncotarget.23502. eCollection 2018 Jan 5.

14.

Upregulation of PIR gene expression induced by human papillomavirus E6 and E7 in epithelial oral and cervical cells.

Carrillo D, Muñoz JP, Huerta H, Leal G, Corvalán A, León O, Calaf GM, Urzúa U, Boccardo E, Tapia JC, Aguayo F.

Open Biol. 2017 Nov;7(11). pii: 170111. doi: 10.1098/rsob.170111.

15.

The conundrum of the Epstein-Barr virus-associated gastric carcinoma in the Americas.

Carrasco-Avino G, Riquelme I, Padilla O, Villaseca M, Aguayo FR, Corvalan AH.

Oncotarget. 2017 Jun 15;8(43):75687-75698. doi: 10.18632/oncotarget.18497. eCollection 2017 Sep 26. Review.

16.

MicroRNA-335-5p is a potential suppressor of metastasis and invasion in gastric cancer.

Sandoval-Bórquez A, Polakovicova I, Carrasco-Véliz N, Lobos-González L, Riquelme I, Carrasco-Avino G, Bizama C, Norero E, Owen GI, Roa JC, Corvalán AH.

Clin Epigenetics. 2017 Oct 17;9:114. doi: 10.1186/s13148-017-0413-8. eCollection 2017.

17.

Structural and functional identification of vasculogenic mimicry in vitro.

Racordon D, Valdivia A, Mingo G, Erices R, Aravena R, Santoro F, Bravo ML, Ramirez C, Gonzalez P, Sandoval A, González A, Retamal C, Kogan MJ, Kato S, Cuello MA, Osorio G, Nualart F, Alvares P, Gago-Arias A, Fabri D, Espinoza I, Sanchez B, Corvalán AH, Pinto MP, Owen GI.

Sci Rep. 2017 Aug 1;7(1):6985. doi: 10.1038/s41598-017-07622-w.

18.

Reprimo tissue-specific expression pattern is conserved between zebrafish and human.

Figueroa RJ, Carrasco-Avino G, Wichmann IA, Lange M, Owen GI, Siekmann AF, Corvalán AH, Opazo JC, Amigo JD.

PLoS One. 2017 May 31;12(5):e0178274. doi: 10.1371/journal.pone.0178274. eCollection 2017.

19.

Expression of teneurins is associated with tumor differentiation and patient survival in ovarian cancer.

Graumann R, Di Capua GA, Oyarzún JE, Vásquez MA, Liao C, Brañes JA, Roa I, Casanello P, Corvalán AH, Owen GI, Delgado I, Zangemeister-Wittke U, Ziegler A.

PLoS One. 2017 May 4;12(5):e0177244. doi: 10.1371/journal.pone.0177244. eCollection 2017.

20.

Small molecule inhibitor screening identifified HSP90 inhibitor 17-AAG as potential therapeutic agent for gallbladder cancer.

Weber H, Valbuena JR, Barbhuiya MA, Stein S, Kunkel H, García P, Bizama C, Riquelme I, Espinoza JA, Kurtz SE, Tyner JW, Calderon JF, Corvalán AH, Grez M, Pandey A, Leal-Rojas P, Roa JC.

Oncotarget. 2017 Apr 18;8(16):26169-26184. doi: 10.18632/oncotarget.15410.

21.

Germline Mutations in PALB2, BRCA1, and RAD51C, Which Regulate DNA Recombination Repair, in Patients With Gastric Cancer.

Sahasrabudhe R, Lott P, Bohorquez M, Toal T, Estrada AP, Suarez JJ, Brea-Fernández A, Cameselle-Teijeiro J, Pinto C, Ramos I, Mantilla A, Prieto R, Corvalan A, Norero E, Alvarez C, Tapia T, Carvallo P, Gonzalez LM, Cock-Rada A, Solano A, Neffa F, Della Valle A, Yau C, Soares G, Borowsky A, Hu N, He LJ, Han XY; Latin American Gastric Cancer Genetics Collaborative Group, Taylor PR, Goldstein AM, Torres J, Echeverry M, Ruiz-Ponte C, Teixeira MR, Carvajal-Carmona LG.

Gastroenterology. 2017 Apr;152(5):983-986.e6. doi: 10.1053/j.gastro.2016.12.010. Epub 2016 Dec 23.

22.

Escaping Antiangiogenic Therapy: Strategies Employed by Cancer Cells.

Pinto MP, Sotomayor P, Carrasco-Avino G, Corvalan AH, Owen GI.

Int J Mol Sci. 2016 Sep 6;17(9). pii: E1489. doi: 10.3390/ijms17091489. Review.

23.

Waking up dormant tumor suppressor genes with zinc fingers, TALEs and the CRISPR/dCas9 system.

Garcia-Bloj B, Moses C, Sgro A, Plani-Lam J, Arooj M, Duffy C, Thiruvengadam S, Sorolla A, Rashwan R, Mancera RL, Leisewitz A, Swift-Scanlan T, Corvalan AH, Blancafort P.

Oncotarget. 2016 Sep 13;7(37):60535-60554. doi: 10.18632/oncotarget.11142.

24.

[Infections and epigenetic changes in cancer].

Corvalán AH, Maturana MJ.

Rev Chil Pediatr. 2016 Jul-Aug;87(4):245-9. doi: 10.1016/j.rchipe.2016.06.008. Epub 2016 Jul 26. Spanish.

25.

Evolutionary history of the reprimo tumor suppressor gene family in vertebrates with a description of a new reprimo gene lineage.

Wichmann IA, Zavala K, Hoffmann FG, Vandewege MW, Corvalán AH, Amigo JD, Owen GI, Opazo JC.

Gene. 2016 Oct 10;591(1):245-254. doi: 10.1016/j.gene.2016.07.036. Epub 2016 Jul 16.

PMID:
27432065
26.

Gastric Cancer: Nanoparticles as Tools to Improve Treatment Efficacy.

Guerrero AR, Oyarzun-Ampuero F, Hassan N, Corvalán AH, Quest AF, Kogan MJ.

Curr Pharm Des. 2016;22(39):5988-5997. Review.

PMID:
27412042
27.

Different Array CGH profiles within hereditary breast cancer tumors associated to BRCA1 expression and overall survival.

Alvarez C, Aravena A, Tapia T, Rozenblum E, Solís L, Corvalán A, Camus M, Alvarez M, Munroe D, Maass A, Carvallo P.

BMC Cancer. 2016 Mar 15;16:219. doi: 10.1186/s12885-016-2261-x.

28.

Study protocol for the Maule Cohort (MAUCO) of chronic diseases, Chile 2014-2024.

Ferreccio C, Roa JC, Bambs C, Vives A, Corvalán AH, Cortés S, Foerster C, Acevedo J, Huidobro A, Passi A, Toro P, Covacevich Y, de la Cruz R, Koshiol J, Olivares M, Miquel JF, Cruz F, Silva R, Quest AF, Kogan MJ, Castro PF, Lavandero S.

BMC Public Health. 2016 Feb 4;16:122. doi: 10.1186/s12889-015-2454-2.

29.

Reprimo as a modulator of cell migration and invasion in the MDA-MB-231 breast cancer cell line.

Buchegger K, Ili C, Riquelme I, Letelier P, Corvalán AH, Brebi P, Huang TH, Roa JC.

Biol Res. 2016 Jan 22;49:5. doi: 10.1186/s40659-016-0066-7.

30.

Helicobacter pylori-induced inflammation and epigenetic changes during gastric carcinogenesis.

Valenzuela MA, Canales J, Corvalán AH, Quest AF.

World J Gastroenterol. 2015 Dec 7;21(45):12742-56. doi: 10.3748/wjg.v21.i45.12742. Review.

31.

Noncoding Genomics in Gastric Cancer and the Gastric Precancerous Cascade: Pathogenesis and Biomarkers.

Sandoval-Bórquez A, Saavedra K, Carrasco-Avino G, Garcia-Bloj B, Fry J, Wichmann I, Corvalán AH.

Dis Markers. 2015;2015:503762. doi: 10.1155/2015/503762. Epub 2015 Aug 26. Review.

32.

Organic and Inorganic Nanoparticles for Prevention and Diagnosis of Gastric Cancer.

Oyarzun-Ampuero F, Guerrero A, Hassan-Lopez N, Morales JO, Bollo S, Corvalan A, Quest AF, Kogan MJ.

Curr Pharm Des. 2015;21(29):4145-54. Review.

PMID:
26323433
33.

Molecular classification of gastric cancer: Towards a pathway-driven targeted therapy.

Riquelme I, Saavedra K, Espinoza JA, Weber H, García P, Nervi B, Garrido M, Corvalán AH, Roa JC, Bizama C.

Oncotarget. 2015 Sep 22;6(28):24750-79. doi: 10.18632/oncotarget.4990. Review.

34.

Loss of Expression of Reprimo, a p53-induced Cell Cycle Arrest Gene, Correlates with Invasive Stage of Tumor Progression and p73 Expression in Gastric Cancer.

Saavedra K, Valbuena J, Olivares W, Marchant MJ, Rodríguez A, Torres-Estay V, Carrasco-Avino G, Guzmán L, Aguayo F, Roa JC, Corvalán AH.

PLoS One. 2015 May 8;10(5):e0125834. doi: 10.1371/journal.pone.0125834. eCollection 2015.

35.

Tobacco smoke activates human papillomavirus 16 p97 promoter and cooperates with high-risk E6/E7 for oxidative DNA damage in lung cells.

Peña N, Carrillo D, Muñoz JP, Chnaiderman J, Urzúa U, León O, Tornesello ML, Corvalán AH, Soto-Rifo R, Aguayo F.

PLoS One. 2015 Apr 1;10(4):e0123029. doi: 10.1371/journal.pone.0123029. eCollection 2015.

36.

A snapshot of cancer in Chile: analytical frameworks for developing a cancer policy.

Jimenez de la Jara J, Bastias G, Ferreccio C, Moscoso C, Sagues S, Cid C, Bronstein E, Herrera C, Nervi B, Corvalan A, Velasquez EV, Gonzalez P, Castellon E, Bustamante E, Oñate S, McNerney E, Sullivan R, Owen GI.

Biol Res. 2015 Jan 26;48:10. doi: 10.1186/0717-6287-48-10. Review.

37.

Expression profiling stratifies mesothelioma tumors and signifies deregulation of spindle checkpoint pathway and microtubule network with therapeutic implications.

Suraokar MB, Nunez MI, Diao L, Chow CW, Kim D, Behrens C, Lin H, Lee S, Raso G, Moran C, Rice D, Mehran R, Lee JJ, Pass HI, Wang J, Momin AA, James BP, Corvalan A, Coombes K, Tsao A, Wistuba II.

Ann Oncol. 2014 Jun;25(6):1184-92. doi: 10.1093/annonc/mdu127. Epub 2014 Mar 24.

38.

Helicobacter pylori-Induced Chronic Gastritis and Assessing Risks for Gastric Cancer.

Carrasco G, Corvalan AH.

Gastroenterol Res Pract. 2013;2013:393015. doi: 10.1155/2013/393015. Epub 2013 Jul 29.

39.

Improved survival of gastric cancer with tumour Epstein-Barr virus positivity: an international pooled analysis.

Camargo MC, Kim WH, Chiaravalli AM, Kim KM, Corvalan AH, Matsuo K, Yu J, Sung JJ, Herrera-Goepfert R, Meneses-Gonzalez F, Kijima Y, Natsugoe S, Liao LM, Lissowska J, Kim S, Hu N, Gonzalez CA, Yatabe Y, Koriyama C, Hewitt SM, Akiba S, Gulley ML, Taylor PR, Rabkin CS.

Gut. 2014 Feb;63(2):236-43. doi: 10.1136/gutjnl-2013-304531. Epub 2013 Apr 12.

40.

A 12-gene set predicts survival benefits from adjuvant chemotherapy in non-small cell lung cancer patients.

Tang H, Xiao G, Behrens C, Schiller J, Allen J, Chow CW, Suraokar M, Corvalan A, Mao J, White MA, Wistuba II, Minna JD, Xie Y.

Clin Cancer Res. 2013 Mar 15;19(6):1577-86. doi: 10.1158/1078-0432.CCR-12-2321. Epub 2013 Jan 28.

41.

[Lynch syndrome: selection of families by microsatellite instability and immunohistochemistry].

Wielandt AM, Zárate AJ, Hurtado C, Orellana P, Alvarez K, Pinto E, Contreras L, Corvalán A, Kronberg U, López-Köstner F.

Rev Med Chil. 2012 Sep;140(9):1132-9. doi: 10.4067/S0034-98872012000900005. Spanish.

42.

Early diagnosis of hepatocellular carcinoma by microRNAs: shining a light from the genome's "dark matter".

Corvalan AH.

Dig Dis Sci. 2012 Nov;57(11):2737-9. doi: 10.1007/s10620-012-2384-0. No abstract available.

PMID:
23014845
43.

Teneurin protein family: an emerging role in human tumorigenesis and drug resistance.

Ziegler A, Corvalán A, Roa I, Brañes JA, Wollscheid B.

Cancer Lett. 2012 Dec 29;326(1):1-7. doi: 10.1016/j.canlet.2012.07.021. Epub 2012 Jul 24. Review.

PMID:
22841666
44.

Functional interaction between human papillomavirus type 16 E6 and E7 oncoproteins and cigarette smoke components in lung epithelial cells.

Muñoz JP, González C, Parra B, Corvalán AH, Tornesello ML, Eizuru Y, Aguayo F.

PLoS One. 2012;7(5):e38178. doi: 10.1371/journal.pone.0038178. Epub 2012 May 25.

45.

Merkel cell polyomavirus in non-small cell lung carcinomas from Chile.

Gheit T, Muñoz JP, Levican J, González C, Ampuero S, Parra B, Gaggero A, Corvalán AH, Meneses M, Tommasino M, Aguayo F.

Exp Mol Pathol. 2012 Aug;93(1):162-6. doi: 10.1016/j.yexmp.2012.04.008. Epub 2012 Apr 16.

PMID:
22537543
46.

High-risk HPV infection after five years in a population-based cohort of Chilean women.

Ferreccio C, Van De Wyngard V, Olcay F, Domínguez MA, Puschel K, Corvalán AH, Franceschi S, Snijders PJ.

Infect Agent Cancer. 2011 Nov 16;6(1):21. doi: 10.1186/1750-9378-6-21.

47.

Identification of the distinctive type i/XhoI+ strain of Epstein-Barr virus in gastric carcinoma in Peru.

Ordonez P, Koriyama C, Ding S, Yoshiwara E, Corvalan AH, Takano J, Chirinos JL, Watanabe J, Miyagui J, Hidalgo H, Chacon P, Linares V, Eizuru Y, Akiba S.

Anticancer Res. 2011 Oct;31(10):3607-13.

PMID:
21965785
48.

Human papillomavirus and Epstein-Barr virus infections in breast cancer from chile.

Aguayo F, Khan N, Koriyama C, González C, Ampuero S, Padilla O, Solís L, Eizuru Y, Corvalán A, Akiba S.

Infect Agent Cancer. 2011 Jun 23;6(1):7. doi: 10.1186/1750-9378-6-7.

49.

Determinants of Epstein-Barr virus-positive gastric cancer: an international pooled analysis.

Camargo MC, Murphy G, Koriyama C, Pfeiffer RM, Kim WH, Herrera-Goepfert R, Corvalan AH, Carrascal E, Abdirad A, Anwar M, Hao Z, Kattoor J, Yoshiwara-Wakabayashi E, Eizuru Y, Rabkin CS, Akiba S.

Br J Cancer. 2011 Jun 28;105(1):38-43. doi: 10.1038/bjc.2011.215. Epub 2011 Jun 7.

50.

Recent patents of DNA methylation biomarkers in gastrointestinal oncology.

Corvalan AH, Maturana MJ.

Recent Pat DNA Gene Seq. 2010 Nov;4(3):202-9. Review.

PMID:
21073436

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