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Vaccination against Salmonella Infection: the Mucosal Way. Gayet R et al. Microbiol Mol Biol Rev. (2017)

Natural Secretory Immunoglobulins Promote Enteric Viral Infections. Turula H et al. J Virol. (2018)

Lipid-Based Particles: Versatile Delivery Systems for Mucosal Vaccination against Infection. Corthésy B et al. Front Immunol. (2018)

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Items: 1 to 50 of 118


Oral Passive Immunization With Plasma-Derived Polyreactive Secretory-Like IgA/M Partially Protects Mice Against Experimental Salmonellosis.

Corthésy B, Monnerat J, Lötscher M, Vonarburg C, Schaub A, Bioley G.

Front Immunol. 2018 Dec 18;9:2970. doi: 10.3389/fimmu.2018.02970. eCollection 2018.


Natural Secretory Immunoglobulins Promote Enteric Viral Infections.

Turula H, Bragazzi Cunha J, Mainou BA, Ramakrishnan SK, Wilke CA, Gonzalez-Hernandez MB, Pry A, Fava J, Bassis CM, Edelman J, Shah YM, Corthesy B, Moore BB, Wobus CE.

J Virol. 2018 Nov 12;92(23). pii: e00826-18. doi: 10.1128/JVI.00826-18. Print 2018 Dec 1.


Lipid-Based Particles: Versatile Delivery Systems for Mucosal Vaccination against Infection.

Corthésy B, Bioley G.

Front Immunol. 2018 Mar 7;9:431. doi: 10.3389/fimmu.2018.00431. eCollection 2018. Review.


Firewalls Prevent Systemic Dissemination of Vectors Derived from Human Adenovirus Type 5 and Suppress Production of Transgene-Encoded Antigen in a Murine Model of Oral Vaccination.

Revaud J, Unterfinger Y, Rol N, Suleman M, Shaw J, Galea S, Gavard F, Lacour SA, Coulpier M, Versillé N, Havenga M, Klonjkowski B, Zanella G, Biacchesi S, Cordonnier N, Corthésy B, Ben Arous J, Richardson JP.

Front Cell Infect Microbiol. 2018 Jan 25;8:6. doi: 10.3389/fcimb.2018.00006. eCollection 2018.


Plasma-Derived Polyreactive Secretory-Like IgA and IgM Opsonizing Salmonella enterica Typhimurium Reduces Invasion and Gut Tissue Inflammation through Agglutination.

Bioley G, Monnerat J, Lötscher M, Vonarburg C, Zuercher A, Corthésy B.

Front Immunol. 2017 Aug 29;8:1043. doi: 10.3389/fimmu.2017.01043. eCollection 2017.


Therapeutic intranasal instillation of allergen-loaded microbubbles suppresses experimental allergic asthma in mice.

Corthésy B, Bioley G.

Biomaterials. 2017 Oct;142:41-51. doi: 10.1016/j.biomaterials.2017.07.019. Epub 2017 Jul 12.


Vaccination against Salmonella Infection: the Mucosal Way.

Gayet R, Bioley G, Rochereau N, Paul S, Corthésy B.

Microbiol Mol Biol Rev. 2017 Jun 14;81(3). pii: e00007-17. doi: 10.1128/MMBR.00007-17. Print 2017 Sep. Review.


SIgA-Shigella Immune Complexes Interact with Dectin-1 and SIGNR3 to Differentially Regulate Mouse Peyer's Patch and Mesenteric Lymph Node Dendritic Cell's Responsiveness.

Mikulic J, Bioley G, Corthésy B.

J Mol Biol. 2017 Jul 21;429(15):2387-2400. doi: 10.1016/j.jmb.2017.05.024. Epub 2017 Jun 3.


Gas-filled microbubbles: Novel mucosal antigen-delivery system for induction of anti-pathogen's immune responses in the gut.

Corthésy B, Bioley G.

Gut Microbes. 2017 Sep 3;8(5):511-519. doi: 10.1080/19490976.2017.1334032. Epub 2017 May 25. Review.


Surface-assembled poly(I:C) on PEGylated PLGA microspheres as vaccine adjuvant: APC activation and bystander cell stimulation.

Hafner AM, Corthésy B, Textor M, Merkle HP.

Int J Pharm. 2016 Nov 30;514(1):176-188. doi: 10.1016/j.ijpharm.2016.07.042.


Intranasal Vaccination With Salmonella-Derived Serodominant Secreted Effector Protein B Associated With Gas-Filled Microbubbles Partially Protects Against Gut Infection in Mice.

Pigny F, Lassus A, Terrettaz J, Tranquart F, Corthésy B, Bioley G.

J Infect Dis. 2016 Aug 1;214(3):438-46. doi: 10.1093/infdis/jiw162. Epub 2016 Apr 27.


Secretory IgA in complex with Lactobacillus rhamnosus potentiates mucosal dendritic cell-mediated Treg cell differentiation via TLR regulatory proteins, RALDH2 and secretion of IL-10 and TGF-β.

Mikulic J, Longet S, Favre L, Benyacoub J, Corthesy B.

Cell Mol Immunol. 2017 Jun;14(6):546-556. doi: 10.1038/cmi.2015.110. Epub 2016 Mar 14.


Efficacy of a therapeutic treatment using gas-filled microbubble-associated phospholipase A2 in a mouse model of honeybee venom allergy.

Corthésy B, Lassus A, Terrettaz J, Tranquart F, Bioley G.

Allergy. 2016 Jul;71(7):957-66. doi: 10.1111/all.12859. Epub 2016 Mar 2.


Delivery of antigen to nasal-associated lymphoid tissue microfold cells through secretory IgA targeting local dendritic cells confers protective immunity.

Rochereau N, Pavot V, Verrier B, Jospin F, Ensinas A, Genin C, Corthésy B, Paul S.

J Allergy Clin Immunol. 2016 Jan;137(1):214-222.e2. doi: 10.1016/j.jaci.2015.07.042. Epub 2015 Sep 26.


Long-term persistence of immunity induced by OVA-coupled gas-filled microbubble vaccination partially protects mice against infection by OVA-expressing Listeria.

Bioley G, Lassus A, Terrettaz J, Tranquart F, Corthésy B.

Biomaterials. 2015 Jul;57:153-60. doi: 10.1016/j.biomaterials.2015.04.008. Epub 2015 Apr 28.


Prophylactic immunization of mice with phospholipase A2-loaded gas-filled microbubbles is protective against Th2-mediated honeybee venom allergy.

Bioley G, Lassus A, Terrettaz J, Tranquart F, Corthésy B.

Clin Exp Allergy. 2016 Jan;46(1):153-62. doi: 10.1111/cea.12555.


Role of secretory IgA in the mucosal sensing of commensal bacteria.

Mathias A, Pais B, Favre L, Benyacoub J, Corthésy B.

Gut Microbes. 2014;5(6):688-95. doi: 10.4161/19490976.2014.983763. Review.


Secretory IgA as a vaccine carrier for delivery of HIV antigen to M cells.

Rochereau N, Pavot V, Verrier B, Ensinas A, Genin C, Corthésy B, Paul S.

Eur J Immunol. 2015 Mar;45(3):773-9. doi: 10.1002/eji.201444816. Epub 2015 Jan 14.


Reconstituted human polyclonal plasma-derived secretory-like IgM and IgA maintain the barrier function of epithelial cells infected with an enteropathogen.

Longet S, Vonarburg C, Lötscher M, Miescher S, Zuercher A, Corthésy B.

J Biol Chem. 2014 Aug 1;289(31):21617-26. doi: 10.1074/jbc.M114.549139. Epub 2014 Jun 20.


Dectin-1 is essential for reverse transcytosis of glycosylated SIgA-antigen complexes by intestinal M cells.

Rochereau N, Drocourt D, Perouzel E, Pavot V, Redelinghuys P, Brown GD, Tiraby G, Roblin X, Verrier B, Genin C, Corthésy B, Paul S.

PLoS Biol. 2013 Sep;11(9):e1001658. doi: 10.1371/journal.pbio.1001658. Epub 2013 Sep 17.


Secretory IgA induces tolerogenic dendritic cells through SIGNR1 dampening autoimmunity in mice.

Diana J, Moura IC, Vaugier C, Gestin A, Tissandie E, Beaudoin L, Corthésy B, Hocini H, Lehuen A, Monteiro RC.

J Immunol. 2013 Sep 1;191(5):2335-43. doi: 10.4049/jimmunol.1300864. Epub 2013 Aug 7.


Multi-faceted functions of secretory IgA at mucosal surfaces.

Corthésy B.

Front Immunol. 2013 Jul 12;4:185. doi: 10.3389/fimmu.2013.00185. eCollection 2013.


Rotavirus specific plasma secretory immunoglobulin in children with acute gastroenteritis and children vaccinated with an attenuated human rotavirus vaccine.

Herrera D, Vásquez C, Corthésy B, Franco MA, Angel J.

Hum Vaccin Immunother. 2013 Nov;9(11):2409-17. Epub 2013 Jul 9.


Abnormal apical-to-basal transport of dietary ovalbumin by secretory IgA stimulates a mucosal Th1 response.

Abed J, Lebreton C, Champier G, Cuvillier A, Cogné M, Meresse B, Dugave C, Garfa-Traoré M, Corthésy B, Cerf-Bensussan N, Heyman M.

Mucosal Immunol. 2014 Mar;7(2):315-24. doi: 10.1038/mi.2013.49. Epub 2013 Jul 10.


Agglutinating secretory IgA preserves intestinal epithelial cell integrity during apical infection by Shigella flexneri.

Mathias A, Longet S, Corthésy B.

Infect Immun. 2013 Aug;81(8):3027-34. doi: 10.1128/IAI.00303-13. Epub 2013 Jun 10.


Particulate formulations for the delivery of poly(I:C) as vaccine adjuvant.

Hafner AM, Corthésy B, Merkle HP.

Adv Drug Deliv Rev. 2013 Oct;65(10):1386-99. doi: 10.1016/j.addr.2013.05.013. Epub 2013 Jun 7. Review.


The effect of vaccines based on ovalbumin coupled to gas-filled microbubbles for reducing infection by ovalbumin-expressing Listeria monocytogenes.

Bioley G, Zehn D, Lassus A, Terrettaz J, Tranquart F, Corthésy B.

Biomaterials. 2013 Jul;34(21):5423-30. doi: 10.1016/j.biomaterials.2013.04.005. Epub 2013 Apr 22.


Human plasma-derived polymeric IgA and IgM antibodies associate with secretory component to yield biologically active secretory-like antibodies.

Longet S, Miled S, Lötscher M, Miescher SM, Zuercher AW, Corthésy B.

J Biol Chem. 2013 Feb 8;288(6):4085-94. doi: 10.1074/jbc.M112.410811. Epub 2012 Dec 18.


Role of secretory IgA in infection and maintenance of homeostasis.

Corthésy B.

Autoimmun Rev. 2013 Apr;12(6):661-5. doi: 10.1016/j.autrev.2012.10.012. Epub 2012 Nov 29. Review.


The role of secretory immunoglobulin A in the natural sensing of commensal bacteria by mouse Peyer's patch dendritic cells.

Rol N, Favre L, Benyacoub J, Corthésy B.

J Biol Chem. 2012 Nov 16;287(47):40074-82. doi: 10.1074/jbc.M112.405001. Epub 2012 Oct 1.


Intragastric and Intranasal Administration of Lactobacillus paracasei NCC2461 Modulates Allergic Airway Inflammation in Mice.

Pellaton C, Nutten S, Thierry AC, Boudousquié C, Barbier N, Blanchard C, Corthésy B, Mercenier A, Spertini F.

Int J Inflam. 2012;2012:686739. doi: 10.1155/2012/686739. Epub 2012 Mar 21.


Gas-filled microbubble-mediated delivery of antigen and the induction of immune responses.

Bioley G, Lassus A, Bussat P, Terrettaz J, Tranquart F, Corthésy B.

Biomaterials. 2012 Sep;33(25):5935-46. doi: 10.1016/j.biomaterials.2012.05.004. Epub 2012 May 29.


Surface assembly of poly(I:C) on PEGylated microspheres to shield from adverse interactions with fibroblasts.

Hafner AM, Burschowsky D, Corthésy B, Textor M, Merkle HP.

J Control Release. 2012 Apr 30;159(2):204-14. doi: 10.1016/j.jconrel.2012.02.002. Epub 2012 Feb 10.


N-Glycans on secretory component: mediators of the interaction between secretory IgA and gram-positive commensals sustaining intestinal homeostasis.

Mathias A, Corthésy B.

Gut Microbes. 2011 Sep 1;2(5):287-93. doi: 10.4161/gmic.2.5.18269. Epub 2011 Sep 1. Review.


The phagocytosis of gas-filled microbubbles by human and murine antigen-presenting cells.

Bioley G, Bussat P, Lassus A, Schneider M, Terrettaz J, Corthésy B.

Biomaterials. 2012 Jan;33(1):333-42. doi: 10.1016/j.biomaterials.2011.09.045. Epub 2011 Oct 8.


Secretory IgA's complex roles in immunity and mucosal homeostasis in the gut.

Mantis NJ, Rol N, Corthésy B.

Mucosal Immunol. 2011 Nov;4(6):603-11. doi: 10.1038/mi.2011.41. Epub 2011 Oct 5. Review.


Transient suppression of Shigella flexneri type 3 secretion by a protective O-antigen-specific monoclonal IgA.

Forbes SJ, Bumpus T, McCarthy EA, Corthésy B, Mantis NJ.

mBio. 2011 May 24;2(3):e00042-11. doi: 10.1128/mBio.00042-11. Print 2011.


Recognition of gram-positive intestinal bacteria by hybridoma- and colostrum-derived secretory immunoglobulin A is mediated by carbohydrates.

Mathias A, Corthésy B.

J Biol Chem. 2011 May 13;286(19):17239-47. doi: 10.1074/jbc.M110.209015. Epub 2011 Mar 21.


Toward protein biomarkers for allergy: CD4+ T cell proteomics in allergic and nonallergic subjects sampled in and out of pollen season.

Blüggel M, Spertini F, Lutter P, Wassenberg J, Audran R, Corthésy B, Müllner S, Blum S, Wattenberg A, Mercenier A, Affolter M, Kussmann M.

J Proteome Res. 2011 Apr 1;10(4):1558-70. doi: 10.1021/pr100939g. Epub 2011 Mar 16.


Tuning the immune response of dendritic cells to surface-assembled poly(I:C) on microspheres through synergistic interactions between phagocytic and TLR3 signaling.

Hafner AM, Corthésy B, Textor M, Merkle HP.

Biomaterials. 2011 Apr;32(10):2651-61. doi: 10.1016/j.biomaterials.2010.12.021. Epub 2011 Jan 8.


Gut permeability and food allergies.

Perrier C, Corthésy B.

Clin Exp Allergy. 2011 Jan;41(1):20-8. doi: 10.1111/j.1365-2222.2010.03639.x. Epub 2010 Nov 11. Review.


Potentiation of polarized intestinal Caco-2 cell responsiveness to probiotics complexed with secretory IgA.

Mathias A, Duc M, Favre L, Benyacoub J, Blum S, Corthésy B.

J Biol Chem. 2010 Oct 29;285(44):33906-13. doi: 10.1074/jbc.M110.135111. Epub 2010 Aug 20.


Role of secretory immunoglobulin A and secretory component in the protection of mucosal surfaces.

Corthésy B.

Future Microbiol. 2010 May;5(5):817-29. doi: 10.2217/fmb.10.39. Review.


Premature replacement of mu with alpha immunoglobulin chains impairs lymphopoiesis and mucosal homing but promotes plasma cell maturation.

Duchez S, Amin R, Cogné N, Delpy L, Sirac C, Pascal V, Corthésy B, Cogné M.

Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3064-9. doi: 10.1073/pnas.0912393107. Epub 2010 Jan 28.


Antigen binding to secretory immunoglobulin A results in decreased sensitivity to intestinal proteases and increased binding to cellular Fc receptors.

Duc M, Johansen FE, Corthésy B.

J Biol Chem. 2010 Jan 8;285(2):953-60. doi: 10.1074/jbc.M109.059220. Epub 2009 Nov 12.


Secretory IgA-mediated neutralization of Shigella flexneri prevents intestinal tissue destruction by down-regulating inflammatory circuits.

Boullier S, Tanguy M, Kadaoui KA, Caubet C, Sansonetti P, Corthésy B, Phalipon A.

J Immunol. 2009 Nov 1;183(9):5879-85. doi: 10.4049/jimmunol.0901838. Epub 2009 Oct 14.


Induction of human papillomavirus oncogene-specific CD8 T-cell effector responses in the genital mucosa of vaccinated mice.

Decrausaz L, Revaz V, Bobst M, Corthésy B, Romero P, Nardelli-Haefliger D.

Int J Cancer. 2010 May 15;126(10):2469-78. doi: 10.1002/ijc.24949.


Allergen-specific antibody and cytokine responses, mast cell reactivity and intestinal permeability upon oral challenge of sensitized and tolerized mice.

Perrier C, Thierry AC, Mercenier A, Corthésy B.

Clin Exp Allergy. 2010 Jan;40(1):153-62. doi: 10.1111/j.1365-2222.2009.03329.x. Epub 2009 Aug 18.


Secretory immunoglobulin A: well beyond immune exclusion at mucosal surfaces.

Corthësy B.

Immunopharmacol Immunotoxicol. 2009 Jun;31(2):174-9. doi: 10.1080/08923970802438441. Review.


Conditioned polarized Caco-2 cell monolayers allow to discriminate for the ability of gut-derived microorganisms to modulate permeability and antigen-induced basophil degranulation.

Thierry AC, Bernasconi E, Mercenier A, Corthésy B.

Clin Exp Allergy. 2009 Apr;39(4):527-36. doi: 10.1111/j.1365-2222.2008.03185.x. Epub 2009 Jan 22.


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