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Items: 1 to 50 of 112

1.

Kcnj6(GIRK2) trisomy is not sufficient for conferring the susceptibility to infantile spasms seen in the Ts65Dn mouse model of down syndrome.

Joshi K, Shen L, Cao F, Dong S, Jia Z, Cortez MA, Snead OC 3rd.

Epilepsy Res. 2018 Sep;145:82-88. doi: 10.1016/j.eplepsyres.2018.06.006. Epub 2018 Jun 12.

PMID:
29929098
2.

Activation of Entorhinal Cortical Projections to the Dentate Gyrus Underlies Social Memory Retrieval.

Leung C, Cao F, Nguyen R, Joshi K, Aqrabawi AJ, Xia S, Cortez MA, Snead OC 3rd, Kim JC, Jia Z.

Cell Rep. 2018 May 22;23(8):2379-2391. doi: 10.1016/j.celrep.2018.04.073.

3.

Radiation Followed by OX40 Stimulation Drives Local and Abscopal Antitumor Effects in an Anti-PD1-Resistant Lung Tumor Model.

Niknam S, Barsoumian HB, Schoenhals JE, Jackson HL, Yanamandra N, Caetano MS, Li A, Younes AI, Cadena A, Cushman TR, Chang JY, Nguyen QN, Gomez DR, Diab A, Heymach JV, Hwu P, Cortez MA, Welsh JW.

Clin Cancer Res. 2018 May 21. doi: 10.1158/1078-0432.CCR-17-3279. [Epub ahead of print]

PMID:
29784675
4.

Indoleamine 2,3-dioxygenase 1 inhibition targets anti-PD1-resistant lung tumors by blocking myeloid-derived suppressor cells.

Li A, Barsoumian HB, Schoenhals JE, Cushman TR, Caetano MS, Wang X, Valdecanas DR, Niknam S, Younes AI, Li G, Woodward WA, Cortez MA, Welsh JW.

Cancer Lett. 2018 Sep 1;431:54-63. doi: 10.1016/j.canlet.2018.05.005. Epub 2018 May 8.

PMID:
29746927
5.

Hypsarrhythmia in epileptic spasms: Synchrony in chaos.

Nenadovic V, Whitney R, Boulet J, Cortez MA.

Seizure. 2018 May;58:55-61. doi: 10.1016/j.seizure.2018.03.026. Epub 2018 Mar 30.

PMID:
29656099
6.

Cancer-associated rs6983267 SNP and its accompanying long noncoding RNA CCAT2 induce myeloid malignancies via unique SNP-specific RNA mutations.

Shah MY, Ferracin M, Pileczki V, Chen B, Redis R, Fabris L, Zhang X, Ivan C, Shimizu M, Rodriguez-Aguayo C, Dragomir M, Van Roosbroeck K, Almeida MI, Ciccone M, Nedelcu D, Cortez MA, Manshouri T, Calin S, Muftuoglu M, Banerjee PP, Badiwi MH, Parker-Thornburg J, Multani A, Welsh JW, Estecio MR, Ling H, Tomuleasa C, Dima D, Yang H, Alvarez H, You MJ, Radovich M, Shpall E, Fabbri M, Rezvani K, Girnita L, Berindan-Neagoe I, Maitra A, Verstovsek S, Fodde R, Bueso-Ramos C, Gagea M, Manero GG, Calin GA.

Genome Res. 2018 Apr;28(4):432-447. doi: 10.1101/gr.225128.117. Epub 2018 Mar 22.

PMID:
29567676
7.

Radiation and Anti-Cancer Vaccines: A Winning Combination.

Cadena A, Cushman TR, Anderson C, Barsoumian HB, Welsh JW, Cortez MA.

Vaccines (Basel). 2018 Jan 30;6(1). pii: E9. doi: 10.3390/vaccines6010009. Review.

8.

Publisher Correction: Transcribed ultraconserved region 339 promotes carcinogenesis by modulating tumor suppressor microRNAs.

Vannini I, Wise PM, Challagundla KB, Plousiou M, Raffini M, Bandini E, Fanini F, Paliaga G, Crawford M, Ferracin M, Ivan C, Fabris L, Davuluri RV, Guo Z, Cortez MA, Zhang X, Chen L, Zhang S, Fernandez-Cymering C, Han L, Carloni S, Salvi S, Ling H, Murtadha M, Neviani P, Gitlitz BJ, Laird-Offringa IA, Nana-Sinkam P, Negrini M, Liang H, Amadori D, Cimmino A, Calin GA, Fabbri M.

Nat Commun. 2018 Jan 8;9(1):160. doi: 10.1038/s41467-017-02485-1.

9.

Absence Seizures as a Feature of Juvenile Myoclonic Epilepsy in Rhodesian Ridgeback Dogs.

Wielaender F, James FMK, Cortez MA, Kluger G, Neßler JN, Tipold A, Lohi H, Fischer A.

J Vet Intern Med. 2018 Jan;32(1):428-432. doi: 10.1111/jvim.14892. Epub 2017 Nov 30.

10.

Transcribed ultraconserved region 339 promotes carcinogenesis by modulating tumor suppressor microRNAs.

Vannini I, Wise PM, Challagundla KB, Plousiou M, Raffini M, Bandini E, Fanini F, Paliaga G, Crawford M, Ferracin M, Ivan C, Fabris L, Davuluri RV, Guo Z, Cortez MA, Zhang X, Chen L, Zhang S, Fernandez-Cymering C, Han L, Carloni S, Salvi S, Ling H, Murtadha M, Neviani P, Gitlitz BJ, Laird-Offringa IA, Nana-Sinkam P, Negrini M, Liang H, Amadori D, Cimmino A, Calin GA, Fabbri M.

Nat Commun. 2017 Nov 27;8(1):1801. doi: 10.1038/s41467-017-01562-9. Erratum in: Nat Commun. 2018 Jan 8;9(1):160.

11.

Diagnostic Utility of Wireless Video-Electroencephalography in Unsedated Dogs.

James FMK, Cortez MA, Monteith G, Jokinen TS, Sanders S, Wielaender F, Fischer A, Lohi H.

J Vet Intern Med. 2017 Sep;31(5):1469-1476. doi: 10.1111/jvim.14789. Epub 2017 Jul 31.

12.

The HGF/c-MET Pathway Is a Driver and Biomarker of VEGFR-inhibitor Resistance and Vascular Remodeling in Non-Small Cell Lung Cancer.

Cascone T, Xu L, Lin HY, Liu W, Tran HT, Liu Y, Howells K, Haddad V, Hanrahan E, Nilsson MB, Cortez MA, Giri U, Kadara H, Saigal B, Park YY, Peng W, Lee JS, Ryan AJ, Jüergensmeier JM, Herbst RS, Wang J, Langley RR, Wistuba II, Lee JJ, Heymach JV.

Clin Cancer Res. 2017 Sep 15;23(18):5489-5501. doi: 10.1158/1078-0432.CCR-16-3216. Epub 2017 May 30.

13.

Uncovering the immune tumor microenvironment in non-small cell lung cancer to understand response rates to checkpoint blockade and radiation.

Schoenhals JE, Seyedin SN, Anderson C, Brooks ED, Li YR, Younes AI, Niknam S, Li A, Barsoumian HB, Cortez MA, Welsh JW.

Transl Lung Cancer Res. 2017 Apr;6(2):148-158. doi: 10.21037/tlcr.2017.03.06. Review.

14.

Neuroligin 3 R451C mutation alters electroencephalography spectral activity in an animal model of autism spectrum disorders.

Liu JJ, Grace KP, Horner RL, Cortez MA, Shao Y, Jia Z.

Mol Brain. 2017 Apr 7;10(1):10. doi: 10.1186/s13041-017-0290-2.

15.

Optimizing Radiotherapy with Immunotherapeutic Approaches.

Schoenhals JE, Skrepnik T, Selek U, Cortez MA, Li A, Welsh JW.

Adv Exp Med Biol. 2017;995:53-71. doi: 10.1007/978-3-319-53156-4_3. Review.

PMID:
28321812
16.

Generalized myoclonic epilepsy with photosensitivity in juvenile dogs caused by a defective DIRAS family GTPase 1.

Wielaender F, Sarviaho R, James F, Hytönen MK, Cortez MA, Kluger G, Koskinen LL, Arumilli M, Kornberg M, Bathen-Noethen A, Tipold A, Rentmeister K, Bhatti SF, Hülsmeyer V, Boettcher IC, Tästensen C, Flegel T, Dietschi E, Leeb T, Matiasek K, Fischer A, Lohi H.

Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):2669-2674. doi: 10.1073/pnas.1614478114. Epub 2017 Feb 21.

17.

Suppression of Type I IFN Signaling in Tumors Mediates Resistance to Anti-PD-1 Treatment That Can Be Overcome by Radiotherapy.

Wang X, Schoenhals JE, Li A, Valdecanas DR, Ye H, Zang F, Tang C, Tang M, Liu CG, Liu X, Krishnan S, Allison JP, Sharma P, Hwu P, Komaki R, Overwijk WW, Gomez DR, Chang JY, Hahn SM, Cortez MA, Welsh JW.

Cancer Res. 2017 Feb 15;77(4):839-850. doi: 10.1158/0008-5472.CAN-15-3142. Epub 2016 Nov 7.

18.

Infantile spasms in down syndrome: Rescue by knockdown of the GIRK2 channel.

Joshi K, Shen L, Michaeli A, Salter M, Thibault-Messier G, Hashmi S, Eubanks JH, Cortez MA, Snead OC.

Ann Neurol. 2016 Oct;80(4):511-21. doi: 10.1002/ana.24749. Epub 2016 Aug 13.

PMID:
27462820
19.

Preclinical Rationale and Clinical Considerations for Radiotherapy Plus Immunotherapy: Going Beyond Local Control.

Schoenhals JE, Seyedin SN, Tang C, Cortez MA, Niknam S, Tsouko E, Chang JY, Hahn SM, Welsh JW.

Cancer J. 2016 Mar-Apr;22(2):130-7. doi: 10.1097/PPO.0000000000000181. Review.

PMID:
27111909
20.

Systemic availability of guanidinoacetate affects GABAA receptor function and seizure threshold in GAMT deficient mice.

Schulze A, Tran C, Levandovskiy V, Patel V, Cortez MA.

Amino Acids. 2016 Aug;48(8):2041-7. doi: 10.1007/s00726-016-2197-0. Epub 2016 Feb 22.

PMID:
26898547
21.

In Vivo Delivery of miR-34a Sensitizes Lung Tumors to Radiation Through RAD51 Regulation.

Cortez MA, Valdecanas D, Niknam S, Peltier HJ, Diao L, Giri U, Komaki R, Calin GA, Gomez DR, Chang JY, Heymach JV, Bader AG, Welsh JW.

Mol Ther Nucleic Acids. 2015 Dec 15;4:e270. doi: 10.1038/mtna.2015.47.

22.

PDL1 Regulation by p53 via miR-34.

Cortez MA, Ivan C, Valdecanas D, Wang X, Peltier HJ, Ye Y, Araujo L, Carbone DP, Shilo K, Giri DK, Kelnar K, Martin D, Komaki R, Gomez DR, Krishnan S, Calin GA, Bader AG, Welsh JW.

J Natl Cancer Inst. 2015 Nov 17;108(1). pii: djv303. doi: 10.1093/jnci/djv303. Print 2016 Jan.

23.

Acute and chronic pharmacological models of generalized absence seizures.

Cortez MA, Kostopoulos GK, Snead OC 3rd.

J Neurosci Methods. 2016 Feb 15;260:175-84. doi: 10.1016/j.jneumeth.2015.08.034. Epub 2015 Sep 5. Review.

PMID:
26343323
24.

Strategies for combining immunotherapy with radiation for anticancer therapy.

Seyedin SN, Schoenhals JE, Lee DA, Cortez MA, Wang X, Niknam S, Tang C, Hong DS, Naing A, Sharma P, Allison JP, Chang JY, Gomez DR, Heymach JV, Komaki RU, Cooper LJ, Welsh JW.

Immunotherapy. 2015;7(9):967-980. doi: 10.2217/imt.15.65. Epub 2015 Aug 27. Review.

25.

Hepatocyte Growth Factor/cMET Pathway Activation Enhances Cancer Hallmarks in Adrenocortical Carcinoma.

Phan LM, Fuentes-Mattei E, Wu W, Velazquez-Torres G, Sircar K, Wood CG, Hai T, Jimenez C, Cote GJ, Ozsari L, Hofmann MC, Zheng S, Verhaak R, Pagliaro L, Cortez MA, Lee MH, Yeung SC, Habra MA.

Cancer Res. 2015 Oct 1;75(19):4131-42. doi: 10.1158/0008-5472.CAN-14-3707. Epub 2015 Aug 17.

26.

Co-occurring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilities.

Skoulidis F, Byers LA, Diao L, Papadimitrakopoulou VA, Tong P, Izzo J, Behrens C, Kadara H, Parra ER, Canales JR, Zhang J, Giri U, Gudikote J, Cortez MA, Yang C, Fan Y, Peyton M, Girard L, Coombes KR, Toniatti C, Heffernan TP, Choi M, Frampton GM, Miller V, Weinstein JN, Herbst RS, Wong KK, Zhang J, Sharma P, Mills GB, Hong WK, Minna JD, Allison JP, Futreal A, Wang J, Wistuba II, Heymach JV.

Cancer Discov. 2015 Aug;5(8):860-77. doi: 10.1158/2159-8290.CD-14-1236. Epub 2015 Jun 11.

27.

The GIRK2 subunit is involved in IS-like seizures induced by GABA(B) receptor agonists.

Blichowski M, Shephard A, Armstrong J, Shen L, Cortez MA, Eubanks JH, Snead OC 3rd.

Epilepsia. 2015 Jul;56(7):1081-7. doi: 10.1111/epi.13034. Epub 2015 May 29.

28.

The Synthesis of Cyclic Poly(ethylene imine) and Exact Linear Analogues: An Evaluation of Gene Delivery Comparing Polymer Architectures.

Cortez MA, Godbey WT, Fang Y, Payne ME, Cafferty BJ, Kosakowska KA, Grayson SM.

J Am Chem Soc. 2015 May 27;137(20):6541-9. doi: 10.1021/jacs.5b00980. Epub 2015 May 12.

PMID:
25927655
29.

LIMK1 regulates long-term memory and synaptic plasticity via the transcriptional factor CREB.

Todorovski Z, Asrar S, Liu J, Saw NM, Joshi K, Cortez MA, Snead OC 3rd, Xie W, Jia Z.

Mol Cell Biol. 2015 Apr;35(8):1316-28. doi: 10.1128/MCB.01263-14. Epub 2015 Feb 2.

30.

Cellular and Kaposi's sarcoma-associated herpes virus microRNAs in sepsis and surgical trauma.

Tudor S, Giza DE, Lin HY, Fabris L, Yoshiaki K, D'Abundo L, Toale KM, Shimizu M, Ferracin M, Challagundla KB, Cortez MA, Fuentes-Mattei E, Tulbure D, Gonzalez C, Henderson J, Row M, Rice TW, Ivan C, Negrini M, Fabbri M, Morris JS, Yeung SC, Vasilescu C, Calin GA.

Cell Death Dis. 2014 Dec 4;5:e1559. doi: 10.1038/cddis.2014.515.

31.

Galectin-1 and immune suppression during radiotherapy.

Welsh JW, Seyedin SN, Cortez MA, Maity A, Hahn SM.

Clin Cancer Res. 2014 Dec 15;20(24):6230-2. doi: 10.1158/1078-0432.CCR-14-2702. Epub 2014 Oct 27.

32.

Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression.

Chen L, Gibbons DL, Goswami S, Cortez MA, Ahn YH, Byers LA, Zhang X, Yi X, Dwyer D, Lin W, Diao L, Wang J, Roybal J, Patel M, Ungewiss C, Peng D, Antonia S, Mediavilla-Varela M, Robertson G, Suraokar M, Welsh JW, Erez B, Wistuba II, Chen L, Peng D, Wang S, Ullrich SE, Heymach JV, Kurie JM, Qin FX.

Nat Commun. 2014 Oct 28;5:5241. doi: 10.1038/ncomms6241.

33.

Combining radiation and immunotherapy: a new systemic therapy for solid tumors?

Tang C, Wang X, Soh H, Seyedin S, Cortez MA, Krishnan S, Massarelli E, Hong D, Naing A, Diab A, Gomez D, Ye H, Heymach J, Komaki R, Allison JP, Sharma P, Welsh JW.

Cancer Immunol Res. 2014 Sep;2(9):831-8. doi: 10.1158/2326-6066.CIR-14-0069. Review.

34.

Paroxysmal alpha activity in Rett syndrome: a case report.

Whitney R, Moharir M, Allen A, Cortez MA.

Pediatr Neurol. 2014 Sep;51(3):421-5. doi: 10.1016/j.pediatrneurol.2014.04.018. Epub 2014 Apr 18.

PMID:
25160549
35.

Therapeutic delivery of miR-200c enhances radiosensitivity in lung cancer.

Cortez MA, Valdecanas D, Zhang X, Zhan Y, Bhardwaj V, Calin GA, Komaki R, Giri DK, Quini CC, Wolfe T, Peltier HJ, Bader AG, Heymach JV, Meyn RE, Welsh JW.

Mol Ther. 2014 Aug;22(8):1494-1503. doi: 10.1038/mt.2014.79. Epub 2014 May 5.

36.

Poly(2 deoxy 2 methacrylamido glucopyranose) b Poly(methacrylate amine)s: Optimization of Diblock Glycopol ycations for Nucleic Acid Delivery.

Li H, Cortez MA, Phillips HR, Wu Y, Reineke TM.

ACS Macro Lett. 2013 Mar 19;2(3). doi: 10.1021/mz300660t.

37.

HINCUTs in cancer: hypoxia-induced noncoding ultraconserved transcripts.

Ferdin J, Nishida N, Wu X, Nicoloso MS, Shah MY, Devlin C, Ling H, Shimizu M, Kumar K, Cortez MA, Ferracin M, Bi Y, Yang D, Czerniak B, Zhang W, Schmittgen TD, Voorhoeve MP, Reginato MJ, Negrini M, Davuluri RV, Kunej T, Ivan M, Calin GA.

Cell Death Differ. 2013 Dec;20(12):1675-87. doi: 10.1038/cdd.2013.119. Epub 2013 Sep 13.

38.

Modulation of c-Met signaling and cellular sensitivity to radiation: potential implications for therapy.

Bhardwaj V, Cascone T, Cortez MA, Amini A, Evans J, Komaki RU, Heymach JV, Welsh JW.

Cancer. 2013 May 15;119(10):1768-75. doi: 10.1002/cncr.27965. Epub 2013 Feb 19. Review.

39.

EEG and neuroimaging correlations in children with lissencephaly.

Menascu S, Weinstock A, Farooq O, Hoffman H, Cortez MA.

Seizure. 2013 Apr;22(3):189-93. doi: 10.1016/j.seizure.2012.12.001. Epub 2013 Jan 6.

40.

GABAB Receptor and Absence Epilepsy.

Han HA, Cortez MA, Snead OC III.

In: Noebels JL, Avoli M, Rogawski MA, Olsen RW, Delgado-Escueta AV, editors. Jasper's Basic Mechanisms of the Epilepsies [Internet]. 4th edition. Bethesda (MD): National Center for Biotechnology Information (US); 2012.

41.

C-Met inhibitor MK-8003 radiosensitizes c-Met-expressing non-small-cell lung cancer cells with radiation-induced c-Met-expression.

Bhardwaj V, Zhan Y, Cortez MA, Ang KK, Molkentine D, Munshi A, Raju U, Komaki R, Heymach JV, Welsh J.

J Thorac Oncol. 2012 Aug;7(8):1211-7. doi: 10.1097/JTO.0b013e318257cc89.

42.

Presumed sturge weber syndrome in a haitian boy: a case of delayed diagnosis.

Giuliari GP, Sadaka A, Cortez MA, Corona A.

Case Rep Ophthalmol Med. 2012;2012:509693. doi: 10.1155/2012/509693. Epub 2012 Mar 27.

43.

Orbital Burkitt's Lymphoma: An Aggressive Presentation.

Giuliari GP, Sadaka A, Cortez MA, Paniagua A.

Case Rep Ophthalmol Med. 2012;2012:354043. doi: 10.1155/2012/354043. Epub 2012 Mar 27.

44.

Circadian profiles of focal epileptic seizures: a need for reappraisal.

Mirzoev A, Bercovici E, Stewart LS, Cortez MA, Snead OC 3rd, Desrocher M.

Seizure. 2012 Jul;21(6):412-6. doi: 10.1016/j.seizure.2012.03.014. Epub 2012 Apr 24. Review.

45.

Circulating microRNAs as noninvasive biomarkers in breast cancer.

Cortez MA, Welsh JW, Calin GA.

Recent Results Cancer Res. 2012;195:151-61. doi: 10.1007/978-3-642-28160-0_13. Review.

46.

Environmental enrichment improves behavioral outcome in the AY-9944 model of childhood atypical absence epilepsy.

Stewart LS, Cortez MA, Snead OC 3rd.

Int J Neurosci. 2012 Aug;122(8):449-57. doi: 10.3109/00207454.2012.677881. Epub 2012 Apr 30.

PMID:
22471338
47.

In vitro effect of glucocorticoids on nasal polyps.

Valera F, Brassesco MS, Castro-Gamero AM, Cortez MA, Queiroz RG, Tone LG, Anselmo-Lima WT.

Braz J Otorhinolaryngol. 2011 Sep-Oct;77(5):605-10. English, Portuguese.

48.

Mania-like behavior induced by genetic dysfunction of the neuron-specific Na+,K+-ATPase α3 sodium pump.

Kirshenbaum GS, Clapcote SJ, Duffy S, Burgess CR, Petersen J, Jarowek KJ, Yücel YH, Cortez MA, Snead OC 3rd, Vilsen B, Peever JH, Ralph MR, Roder JC.

Proc Natl Acad Sci U S A. 2011 Nov 1;108(44):18144-9. doi: 10.1073/pnas.1108416108. Epub 2011 Oct 24. Erratum in: Proc Natl Acad Sci U S A. 2012 Feb 7;109(6):2174.

49.

Evidence that clozapine directly interacts on the GABAB receptor.

Wu Y, Blichowski M, Daskalakis ZJ, Wu Z, Liu CC, Cortez MA, Snead OC 3rd.

Neuroreport. 2011 Sep 14;22(13):637-41. doi: 10.1097/WNR.0b013e328349739b.

PMID:
21753741
50.

Treatment of infantile spasms: emerging insights from clinical and basic science perspectives.

Stafstrom CE, Arnason BG, Baram TZ, Catania A, Cortez MA, Glauser TA, Pranzatelli MR, Riikonen R, Rogawski MA, Shinnar S, Swann JW.

J Child Neurol. 2011 Nov;26(11):1411-21. doi: 10.1177/0883073811413129. Epub 2011 Jun 30. Review.

PMID:
21719797

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