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Items: 4


Elastase 3B mutation links to familial pancreatitis with diabetes and pancreatic adenocarcinoma.

Moore PC, Cortez JT, Chamberlain CE, Alba D, Berger AC, Quandt Z, Chan A, Cheng MH, Bautista JL, Peng J, German MS, Anderson M, Oakes SA.

J Clin Invest. 2019 Aug 1;130. pii: 129961. doi: 10.1172/JCI129961.


The epigenetic regulator ATF7ip inhibits Il2 expression, regulating Th17 responses.

Sin JH, Zuckerman C, Cortez JT, Eckalbar WL, Erle DJ, Anderson MS, Waterfield MR.

J Exp Med. 2019 Sep 2;216(9):2024-2037. doi: 10.1084/jem.20182316. Epub 2019 Jun 19.


A large CRISPR-induced bystander mutation causes immune dysregulation.

Simeonov DR, Brandt AJ, Chan AY, Cortez JT, Li Z, Woo JM, Lee Y, Carvalho CMB, Indart AC, Roth TL, Zou J, May AP, Lupski JR, Anderson MS, Buaas FW, Rokhsar DS, Marson A.

Commun Biol. 2019 Feb 18;2:70. doi: 10.1038/s42003-019-0321-x. eCollection 2019.


The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance.

Waterfield M, Khan IS, Cortez JT, Fan U, Metzger T, Greer A, Fasano K, Martinez-Llordella M, Pollack JL, Erle DJ, Su M, Anderson MS.

Nat Immunol. 2014 Mar;15(3):258-65. doi: 10.1038/ni.2820. Epub 2014 Jan 26. Erratum in: Nat Immunol. 2014 Sep;15(9):894.

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