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Items: 10


The endoplasmic reticulum acetyltransferases ATase1/NAT8B and ATase2/NAT8 are differentially regulated to adjust engagement of the secretory pathway.

Rigby MJ, Ding Y, Farrugia MA, Feig M, Cortese GP, Mitchell H, Burger C, Puglielli L.

J Neurochem. 2020 Jan 16:e14958. doi: 10.1111/jnc.14958. [Epub ahead of print]


Parkinson's disease-linked Parkin mutations impair glutamatergic signaling in hippocampal neurons.

Zhu M, Cortese GP, Waites CL.

BMC Biol. 2018 Sep 10;16(1):100. doi: 10.1186/s12915-018-0567-7.


Aging and an Immune Challenge Interact to Produce Prolonged, but Not Permanent, Reductions in Hippocampal L-LTP and mBDNF in a Rodent Model with Features of Delirium.

Tanaka N, Cortese GP, Barrientos RM, Maier SF, Patterson SL.

eNeuro. 2018 Jun 4;5(3). pii: ENEURO.0009-18.2018. doi: 10.1523/ENEURO.0009-18.2018. eCollection 2018 May-Jun.


Environmental enrichment improves hippocampal function in aged rats by enhancing learning and memory, LTP, and mGluR5-Homer1c activity.

Cortese GP, Olin A, O'Riordan K, Hullinger R, Burger C.

Neurobiol Aging. 2018 Mar;63:1-11. doi: 10.1016/j.neurobiolaging.2017.11.004. Epub 2017 Nov 16.


Parkin Deficiency Reduces Hippocampal Glutamatergic Neurotransmission by Impairing AMPA Receptor Endocytosis.

Cortese GP, Zhu M, Williams D, Heath S, Waites CL.

J Neurosci. 2016 Nov 30;36(48):12243-12258.


Neuroinflammatory challenges compromise neuronal function in the aging brain: Postoperative cognitive delirium and Alzheimer's disease.

Cortese GP, Burger C.

Behav Brain Res. 2017 Mar 30;322(Pt B):269-279. doi: 10.1016/j.bbr.2016.08.027. Epub 2016 Aug 17. Review.


The ubiquitin E3 ligase parkin regulates the proapoptotic function of Bax.

Johnson BN, Berger AK, Cortese GP, Lavoie MJ.

Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):6283-8. doi: 10.1073/pnas.1113248109. Epub 2012 Mar 29.


Aging and a peripheral immune challenge interact to reduce mature brain-derived neurotrophic factor and activation of TrkB, PLCgamma1, and ERK in hippocampal synaptoneurosomes.

Cortese GP, Barrientos RM, Maier SF, Patterson SL.

J Neurosci. 2011 Mar 16;31(11):4274-9. doi: 10.1523/JNEUROSCI.5818-10.2011.


Parkin selectively alters the intrinsic threshold for mitochondrial cytochrome c release.

Berger AK, Cortese GP, Amodeo KD, Weihofen A, Letai A, LaVoie MJ.

Hum Mol Genet. 2009 Nov 15;18(22):4317-28. doi: 10.1093/hmg/ddp384. Epub 2009 Aug 13.


The effects of oxidative stress on parkin and other E3 ligases.

LaVoie MJ, Cortese GP, Ostaszewski BL, Schlossmacher MG.

J Neurochem. 2007 Dec;103(6):2354-68. Epub 2007 Sep 19.

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