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Items: 12


Cyclin-Dependent Kinase Inhibitors as Anticancer Therapeutics.

Law ME, Corsino PE, Narayan S, Law BK.

Mol Pharmacol. 2015 Nov;88(5):846-52. doi: 10.1124/mol.115.099325. Epub 2015 May 27.


Small-molecule Bax agonists for cancer therapy.

Xin M, Li R, Xie M, Park D, Owonikoko TK, Sica GL, Corsino PE, Zhou J, Ding C, White MA, Magis AT, Ramalingam SS, Curran WJ, Khuri FR, Deng X.

Nat Commun. 2014 Sep 17;5:4935. doi: 10.1038/ncomms5935.


Signaling mechanisms that suppress the cytostatic actions of rapamycin.

Jahn SC, Law ME, Corsino PE, Davis BJ, Harrison JK, Law BK.

PLoS One. 2014 Jun 13;9(6):e99927. doi: 10.1371/journal.pone.0099927. eCollection 2014.


Assembly, activation, and substrate specificity of cyclin D1/Cdk2 complexes.

Jahn SC, Law ME, Corsino PE, Rowe TC, Davis BJ, Law BK.

Biochemistry. 2013 May 21;52(20):3489-501. doi: 10.1021/bi400047u. Epub 2013 May 9.


Constitutive Cdk2 activity promotes aneuploidy while altering the spindle assembly and tetraploidy checkpoints.

Jahn SC, Corsino PE, Davis BJ, Law ME, Nørgaard P, Law BK.

J Cell Sci. 2013 Mar 1;126(Pt 5):1207-17. doi: 10.1242/jcs.117382. Epub 2013 Jan 15.


An in vivo model of epithelial to mesenchymal transition reveals a mitogenic switch.

Jahn SC, Law ME, Corsino PE, Parker NN, Pham K, Davis BJ, Lu J, Law BK.

Cancer Lett. 2012 Dec 30;326(2):183-90. doi: 10.1016/j.canlet.2012.08.013. Epub 2012 Aug 17.


Glucocorticoids and histone deacetylase inhibitors cooperate to block the invasiveness of basal-like breast cancer cells through novel mechanisms.

Law ME, Corsino PE, Jahn SC, Davis BJ, Chen S, Patel B, Pham K, Lu J, Sheppard B, Nørgaard P, Hong J, Higgins P, Kim JS, Luesch H, Law BK.

Oncogene. 2013 Mar 7;32(10):1316-29. doi: 10.1038/onc.2012.138. Epub 2012 Apr 30.


TGF-beta antiproliferative effects in tumor suppression.

Jahn SC, Law ME, Corsino PE, Law BK.

Front Biosci (Schol Ed). 2012 Jan 1;4:749-66. Review.


Amino acid Asp181 of 5'-flap endonuclease 1 is a useful target for chemotherapeutic development.

Panda H, Jaiswal AS, Corsino PE, Armas ML, Law BK, Narayan S.

Biochemistry. 2009 Oct 27;48(42):9952-8. doi: 10.1021/bi9010754.


Mammary tumors initiated by constitutive Cdk2 activation contain an invasive basal-like component.

Corsino PE, Davis BJ, Nørgaard PH, Parker NN, Law M, Dunn W, Law BK.

Neoplasia. 2008 Nov;10(11):1240-52.


Discovery of novel DNA gyrase inhibitors by high-throughput virtual screening.

Ostrov DA, Hernández Prada JA, Corsino PE, Finton KA, Le N, Rowe TC.

Antimicrob Agents Chemother. 2007 Oct;51(10):3688-98. Epub 2007 Aug 6.


Crystal structure of the TetR/CamR family repressor Mycobacterium tuberculosis EthR implicated in ethionamide resistance.

Dover LG, Corsino PE, Daniels IR, Cocklin SL, Tatituri V, Besra GS, Fütterer K.

J Mol Biol. 2004 Jul 23;340(5):1095-105.


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