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Items: 1 to 50 of 131

1.

Demonstrating specificity of bioactive peptide nucleic acids (PNAs) targeting microRNAs for practical laboratory classes of applied biochemistry and pharmacology.

Gasparello J, Papi C, Zurlo M, Corradini R, Gambari R, Finotti A.

PLoS One. 2019 Sep 11;14(9):e0221923. doi: 10.1371/journal.pone.0221923. eCollection 2019.

2.

Targeting miR‑155‑5p and miR‑221‑3p by peptide nucleic acids induces caspase‑3 activation and apoptosis in temozolomide‑resistant T98G glioma cells.

Milani R, Brognara E, Fabbri E, Manicardi A, Corradini R, Finotti A, Gasparello J, Borgatti M, Cosenza LC, Lampronti I, Dechecchi MC, Cabrini G, Gambari R.

Int J Oncol. 2019 Jul;55(1):59-68. doi: 10.3892/ijo.2019.4810. Epub 2019 May 23.

3.

Physiological expression of miR-130a during differentiation of CD34+ human hematopoietic stem cells results in the inhibition of monocyte differentiation.

Mammoli F, Parenti S, Lomiento M, Gemelli C, Atene CG, Grande A, Corradini R, Manicardi A, Fantini S, Zanocco-Marani T, Ferrari S.

Exp Cell Res. 2019 Sep 1;382(1):111445. doi: 10.1016/j.yexcr.2019.05.026. Epub 2019 May 29.

4.

64Cu and fluorescein labeled anti-miRNA peptide nucleic acids for the detection of miRNA expression in living cells.

Croci S, Manicardi A, Rubagotti S, Bonacini M, Iori M, Capponi PC, Cicoria G, Parmeggiani M, Salvarani C, Versari A, Corradini R, Asti M.

Sci Rep. 2019 Mar 4;9(1):3376. doi: 10.1038/s41598-018-35800-x.

5.

Efficient cell penetration and delivery of peptide nucleic acids by an argininocalix[4]arene.

Gasparello J, Manicardi A, Casnati A, Corradini R, Gambari R, Finotti A, Sansone F.

Sci Rep. 2019 Feb 28;9(1):3036. doi: 10.1038/s41598-019-39211-4.

6.

Enhancing the Expression of CFTR Using Antisense Molecules against MicroRNA miR-145-5p.

Finotti A, Gasparello J, Fabbri E, Tamanini A, Corradini R, Dechecchi MC, Cabrini G, Gambari R.

Am J Respir Crit Care Med. 2019 Jun 1;199(11):1443-1444. doi: 10.1164/rccm.201901-0019LE. No abstract available.

7.

Single-Walled Carbon Nanotubes as Enhancing Substrates for PNA-Based Amperometric Genosensors.

Fortunati S, Rozzi A, Curti F, Giannetto M, Corradini R, Careri M.

Sensors (Basel). 2019 Jan 30;19(3). pii: E588. doi: 10.3390/s19030588.

8.

Novel amperometric genosensor based on peptide nucleic acid (PNA) probes immobilized on carbon nanotubes-screen printed electrodes for the determination of trace levels of non-amplified DNA in genetically modified (GM) soy.

Fortunati S, Rozzi A, Curti F, Giannetto M, Corradini R, Careri M.

Biosens Bioelectron. 2019 Mar 15;129:7-14. doi: 10.1016/j.bios.2019.01.020. Epub 2019 Jan 17.

PMID:
30682690
9.

Control of Probe Density at DNA Biosensor Surfaces Using Poly(l-lysine) with Appended Reactive Groups.

Movilli J, Rozzi A, Ricciardi R, Corradini R, Huskens J.

Bioconjug Chem. 2018 Dec 19;29(12):4110-4118. doi: 10.1021/acs.bioconjchem.8b00733. Epub 2018 Nov 26.

10.

Selective Functionalization with PNA of Silicon Nanowires on Silicon Oxide Substrates.

Veerbeek J, Steen R, Vijselaar W, Rurup WF, Korom S, Rozzi A, Corradini R, Segerink L, Huskens J.

Langmuir. 2018 Sep 25;34(38):11395-11404. doi: 10.1021/acs.langmuir.8b02401. Epub 2018 Sep 12.

11.

Special Issue: Molecular Properties and the Applications of Peptide Nucleic Acids.

Corradini R.

Molecules. 2018 Aug 8;23(8). pii: E1977. doi: 10.3390/molecules23081977.

12.

Loading of PNA and Other Molecular Payloads on Inorganic Nanostructures for Theranostics.

Bertucci A, Silvestrini S, Corradini R, De Cola L.

Methods Mol Biol. 2018;1811:65-77. doi: 10.1007/978-1-4939-8582-1_5.

PMID:
29926446
13.

Preparation of Anti-miR PNAs for Drug Development and Nanomedicine.

Manicardi A, Gambari R, de Cola L, Corradini R.

Methods Mol Biol. 2018;1811:49-63. doi: 10.1007/978-1-4939-8582-1_4.

PMID:
29926445
14.

A Peptide Nucleic Acid against MicroRNA miR-145-5p Enhances the Expression of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) in Calu-3 Cells.

Fabbri E, Tamanini A, Jakova T, Gasparello J, Manicardi A, Corradini R, Sabbioni G, Finotti A, Borgatti M, Lampronti I, Munari S, Dechecchi MC, Cabrini G, Gambari R.

Molecules. 2017 Dec 29;23(1). pii: E71. doi: 10.3390/molecules23010071.

15.

Synthesis and Improved Cross-Linking Properties of C5-Modified Furan Bearing PNAs.

Elskens J, Manicardi A, Costi V, Madder A, Corradini R.

Molecules. 2017 Nov 20;22(11). pii: E2010. doi: 10.3390/molecules22112010.

16.

Focus on PNA Flexibility and RNA Binding using Molecular Dynamics and Metadynamics.

Verona MD, Verdolino V, Palazzesi F, Corradini R.

Sci Rep. 2017 Feb 17;7:42799. doi: 10.1038/srep42799.

17.

DNA Detection by Flow Cytometry using PNA-Modified Metal-Organic Framework Particles.

Mejia-Ariza R, Rosselli J, Breukers C, Manicardi A, Terstappen LW, Corradini R, Huskens J.

Chemistry. 2017 Mar 23;23(17):4180-4186. doi: 10.1002/chem.201605803. Epub 2017 Feb 28.

18.

Strategies for delivery of faecal occult blood test kits and participation to colorectal cancer screening in the Emilia-Romagna Region of Italy.

Mancini S, Ravaioli A, Falcini F, Giuliani O, Corradini R, De Girolamo G, Goldoni CA, Finarelli AC, Naldoni C, Landi P, Sassoli de Bianchi P, Bucchi L.

Eur J Cancer Care (Engl). 2018 Jan;27(1). doi: 10.1111/ecc.12631. Epub 2016 Dec 29.

PMID:
28032381
19.

A Bifunctional Monomer for On-Resin Synthesis of Polyfunctional PNAs and Tailored Induced-Fit Switching Probes.

Manicardi A, Bertucci A, Rozzi A, Corradini R.

Org Lett. 2016 Nov 4;18(21):5452-5455. Epub 2016 Oct 21.

20.

Furan-PNA: a mildly inducible irreversible interstrand crosslinking system targeting single and double stranded DNA.

Manicardi A, Gyssels E, Corradini R, Madder A.

Chem Commun (Camb). 2016 May 25;52(42):6930-3. doi: 10.1039/c6cc02062c. Epub 2016 May 5.

PMID:
27147261
21.

Ambient temperature and FIT performance in the Emilia-Romagna colorectal cancer screening programme.

De Girolamo G, Goldoni CA, Corradini R, Giuliani O, Falcini F, Sassoli De'Bianchi P, Naldoni C, Zauli Sajani S.

J Med Screen. 2016 Dec;23(4):186-191. Epub 2016 Apr 28.

PMID:
27125499
22.

Effect of chirality in gamma-PNA: PNA interaction, another piece in the picture.

Manicardi A, Corradini R.

Artif DNA PNA XNA. 2014 Dec 15;5(3):e1131801. doi: 10.1080/1949095X.2015.1131801.

23.

High levels of apoptosis are induced in human glioma cell lines by co-administration of peptide nucleic acids targeting miR-221 and miR-222.

Brognara E, Fabbri E, Montagner G, Gasparello J, Manicardi A, Corradini R, Bianchi N, Finotti A, Breveglieri G, Borgatti M, Lampronti I, Milani R, Dechecchi MC, Cabrini G, Gambari R.

Int J Oncol. 2016 Mar;48(3):1029-38. doi: 10.3892/ijo.2015.3308. Epub 2015 Dec 24.

PMID:
26708164
24.

Breakable Hybrid Organosilica Nanocapsules for Protein Delivery.

Prasetyanto EA, Bertucci A, Septiadi D, Corradini R, Castro-Hartmann P, De Cola L.

Angew Chem Int Ed Engl. 2016 Mar 1;55(10):3323-7. doi: 10.1002/anie.201508288. Epub 2015 Dec 8.

PMID:
26643574
25.

Structural Studies on Porphyrin-PNA Conjugates in Parallel PNA:PNA Duplexes: Effect of Stacking Interactions on Helicity.

Accetta A, Petrovic AG, Marchelli R, Berova N, Corradini R.

Chirality. 2015 Dec;27(12):864-74. doi: 10.1002/chir.22521. Epub 2015 Sep 28.

PMID:
26412743
26.

Combined Delivery of Temozolomide and Anti-miR221 PNA Using Mesoporous Silica Nanoparticles Induces Apoptosis in Resistant Glioma Cells.

Bertucci A, Prasetyanto EA, Septiadi D, Manicardi A, Brognara E, Gambari R, Corradini R, De Cola L.

Small. 2015 Nov 11;11(42):5687-95. doi: 10.1002/smll.201500540. Epub 2015 Sep 23.

PMID:
26395266
27.

Homocysteine levels in schizophrenia patients newly admitted to an acute psychiatric ward.

Di Lorenzo R, Amoretti A, Baldini S, Soli M, Landi G, Pollutri G, Corradini R, Ferri P.

Acta Neuropsychiatr. 2015 Dec;27(6):336-44. doi: 10.1017/neu.2015.30. Epub 2015 May 28.

PMID:
26017629
28.

Peptide nucleic acids targeting β-globin mRNAs selectively inhibit hemoglobin production in murine erythroleukemia cells.

Montagner G, Gemmo C, Fabbri E, Manicardi A, Accardo I, Bianchi N, Finotti A, Breveglieri G, Salvatori F, Borgatti M, Lampronti I, Bresciani A, Altamura S, Corradini R, Gambari R.

Int J Mol Med. 2015 Jan;35(1):51-8. doi: 10.3892/ijmm.2014.2005. Epub 2014 Nov 14.

29.

Toward peptide nucleic acid (PNA) directed peptide translation using ester based aminoacyl transfer.

Singhal A, Bagnacani V, Corradini R, Nielsen PE.

ACS Chem Biol. 2014 Nov 21;9(11):2612-20. doi: 10.1021/cb5005349. Epub 2014 Sep 18.

30.

Pyrene-modified PNAs: Stacking interactions and selective excimer emission in PNA2DNA triplexes.

Manicardi A, Guidi L, Ghidini A, Corradini R.

Beilstein J Org Chem. 2014 Jul 2;10:1495-503. doi: 10.3762/bjoc.10.154. eCollection 2014.

31.

Detection of unamplified genomic DNA by a PNA-based microstructured optical fiber (MOF) Bragg-grating optofluidic system.

Bertucci A, Manicardi A, Candiani A, Giannetti S, Cucinotta A, Spoto G, Konstantaki M, Pissadakis S, Selleri S, Corradini R.

Biosens Bioelectron. 2015 Jan 15;63:248-254. doi: 10.1016/j.bios.2014.07.047. Epub 2014 Jul 25.

PMID:
25104434
32.

Multifunctional inorganic nanocontainers for DNA and drug delivery into living cells.

Lülf H, Bertucci A, Septiadi D, Corradini R, De Cola L.

Chemistry. 2014 Aug 25;20(35):10900-4. doi: 10.1002/chem.201403232. Epub 2014 Jul 8.

PMID:
25042168
33.

Intracellular delivery of peptide nucleic acid and organic molecules using zeolite-L nanocrystals.

Bertucci A, Lülf H, Septiadi D, Manicardi A, Corradini R, De Cola L.

Adv Healthc Mater. 2014 Nov;3(11):1812-7. doi: 10.1002/adhm.201400116. Epub 2014 May 2.

PMID:
24789252
34.

Uptake by human glioma cell lines and biological effects of a peptide-nucleic acids targeting miR-221.

Brognara E, Fabbri E, Bazzoli E, Montagner G, Ghimenton C, Eccher A, Cantù C, Manicardi A, Bianchi N, Finotti A, Breveglieri G, Borgatti M, Corradini R, Bezzerri V, Cabrini G, Gambari R.

J Neurooncol. 2014 May;118(1):19-28. doi: 10.1007/s11060-014-1405-6. Epub 2014 Mar 5.

PMID:
24595467
35.

Use of peptide nucleic acids (PNAs) for genotyping by solution and surface methods.

Sforza S, Tedeschi T, Bencivenni M, Tonelli A, Corradini R, Marchelli R.

Methods Mol Biol. 2014;1050:143-57. doi: 10.1007/978-1-62703-553-8_12.

PMID:
24297357
36.

Chiral PNAs with constrained open-chain backbones.

Corradini R, Tedeschi T, Sforza S, Marchelli R.

Methods Mol Biol. 2014;1050:19-35. doi: 10.1007/978-1-62703-553-8_3.

PMID:
24297348
37.

Molecular methods for validation of the biological activity of peptide nucleic acids targeting microRNAs.

Brognara E, Fabbri E, Bianchi N, Finotti A, Corradini R, Gambari R.

Methods Mol Biol. 2014;1095:165-76. doi: 10.1007/978-1-62703-703-7_14.

PMID:
24166312
38.

PNA-NLS conjugates as single-molecular activators of target sites in double-stranded DNA for site-selective scission.

Aiba Y, Hamano Y, Kameshima W, Araki Y, Wada T, Accetta A, Sforza S, Corradini R, Marchelli R, Komiyama M.

Org Biomol Chem. 2013 Aug 28;11(32):5233-8. doi: 10.1039/c3ob40947c.

PMID:
23820872
39.

Label-free DNA biosensor based on a peptide nucleic acid-functionalized microstructured optical fiber-Bragg grating.

Candiani A, Bertucci A, Giannetti S, Konstantaki M, Manicardi A, Pissadakis S, Cucinotta A, Corradini R, Selleri S.

J Biomed Opt. 2013 May;18(5):57004. doi: 10.1117/1.JBO.18.5.057004.

40.

Colonoscopic surveillance of first-degree relatives of colorectal cancer patients in a faecal occult blood screening programme.

Sassoli de Bianchi P, Campari C, Mancini S, Giuliani O, Landi P, Paterlini L, Naldoni C, Finarelli AC, Falcini F, Ponz de Leon M, Sassatelli R, Borciani E, Fornari F, Gatti G, Zatelli M, Zurlini C, Rossi F, Corradini R, Olivetti R, Manfredi M, Baldazzi P, Nannini R, Zanarini S, Matarese VG, Palmonari C, Triossi O, Gordini S, Vattiato R, Colamartini A, Palazzi M, Severi M, Briganti L, Giovanardi M, Casale C, Bucchi L.

Cancer Epidemiol. 2013 Aug;37(4):469-73. doi: 10.1016/j.canep.2013.04.004. Epub 2013 May 14.

PMID:
23683843
41.

Peptide nucleic acids targeting miR-221 modulate p27Kip1 expression in breast cancer MDA-MB-231 cells.

Brognara E, Fabbri E, Aimi F, Manicardi A, Bianchi N, Finotti A, Breveglieri G, Borgatti M, Corradini R, Marchelli R, Gambari R.

Int J Oncol. 2012 Dec;41(6):2119-27. doi: 10.3892/ijo.2012.1632. Epub 2012 Sep 19.

PMID:
22992757
42.

Letter from the editors.

Corradini R, Sforza S.

Artif DNA PNA XNA. 2012 Apr-Jun;3(2):29-30. doi: 10.4161/adna.21100. Epub 2012 Apr 1. No abstract available.

43.

PNA bearing 5-azidomethyluracil: a novel approach for solid and solution phase modification.

Manicardi A, Accetta A, Tedeschi T, Sforza S, Marchelli R, Corradini R.

Artif DNA PNA XNA. 2012 Apr-Jun;3(2):53-62. doi: 10.4161/adna.20158. Epub 2012 Apr 1.

44.

Selective recognition of DNA from olive leaves and olive oil by PNA and modified-PNA microarrays.

Rossi S, Calabretta A, Tedeschi T, Sforza S, Arcioni S, Baldoni L, Corradini R, Marchelli R.

Artif DNA PNA XNA. 2012 Apr-Jun;3(2):63-72. doi: 10.4161/adna.20603. Epub 2012 Apr 1.

45.

Cellular uptakes, biostabilities and anti-miR-210 activities of chiral arginine-PNAs in leukaemic K562 cells.

Manicardi A, Fabbri E, Tedeschi T, Sforza S, Bianchi N, Brognara E, Gambari R, Marchelli R, Corradini R.

Chembiochem. 2012 Jun 18;13(9):1327-37. doi: 10.1002/cbic.201100745. Epub 2012 May 25.

46.

Adult patients with sporadic polycystic kidney disease: the importance of screening for mutations in the PKD1 and PKD2 genes.

Neumann HP, Bacher J, Nabulsi Z, Ortiz Brüchle N, Hoffmann MM, Schaeffner E, Nürnberger J, Cybulla M, Wilpert J, Riegler P, Corradini R, Kraemer-Guth A, Azurmendi P, Nunez M, Gläsker S, Zerres K, Jilg C.

Int Urol Nephrol. 2012 Dec;44(6):1753-62. doi: 10.1007/s11255-012-0125-0. Epub 2012 Feb 25.

PMID:
22367170
47.

Peptide nucleic acid molecular beacons for the detection of PCR amplicons in droplet-based microfluidic devices.

Zanoli LM, Licciardello M, D'Agata R, Lantano C, Calabretta A, Corradini R, Marchelli R, Spoto G.

Anal Bioanal Chem. 2013 Jan;405(2-3):615-24. doi: 10.1007/s00216-011-5638-3. Epub 2012 Jan 3.

PMID:
22212864
48.

miRNA therapeutics: delivery and biological activity of peptide nucleic acids targeting miRNAs.

Fabbri E, Brognara E, Borgatti M, Lampronti I, Finotti A, Bianchi N, Sforza S, Tedeschi T, Manicardi A, Marchelli R, Corradini R, Gambari R.

Epigenomics. 2011 Dec;3(6):733-45. doi: 10.2217/epi.11.90. Review.

PMID:
22126292
49.

Antitumor activity of sustained N-myc reduction in rhabdomyosarcomas and transcriptional block by antigene therapy.

Tonelli R, McIntyre A, Camerin C, Walters ZS, Di Leo K, Selfe J, Purgato S, Missiaglia E, Tortori A, Renshaw J, Astolfi A, Taylor KR, Serravalle S, Bishop R, Nanni C, Valentijn LJ, Faccini A, Leuschner I, Formica S, Reis-Filho JS, Ambrosini V, Thway K, Franzoni M, Summersgill B, Marchelli R, Hrelia P, Cantelli-Forti G, Fanti S, Corradini R, Pession A, Shipley J.

Clin Cancer Res. 2012 Feb 1;18(3):796-807. doi: 10.1158/1078-0432.CCR-11-1981. Epub 2011 Nov 7.

50.

Modulation of the biological activity of microRNA-210 with peptide nucleic acids (PNAs).

Fabbri E, Manicardi A, Tedeschi T, Sforza S, Bianchi N, Brognara E, Finotti A, Breveglieri G, Borgatti M, Corradini R, Marchelli R, Gambari R.

ChemMedChem. 2011 Dec 9;6(12):2192-202. doi: 10.1002/cmdc.201100270. Epub 2011 Oct 19.

PMID:
22012891

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