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Re: 'Application of the key characteristics of carcinogens in cancer hazard evaluation': response to Goodman, Lynch and Rhomberg.

Guyton KZ, Rusyn I, Chiu WA, Corpet DE, van den Berg M, Ross MK, Christiani DC, Beland FA, Smith MT.

Carcinogenesis. 2018 Jul 30;39(8):1091-1093. doi: 10.1093/carcin/bgy082. No abstract available.


Targeting Colon Luminal Lipid Peroxidation Limits Colon Carcinogenesis Associated with Red Meat Consumption.

Martin OCB, Naud N, Taché S, Debrauwer L, Chevolleau S, Dupuy J, Chantelauze C, Durand D, Pujos-Guillot E, Blas-Y-Estrada F, Urbano C, Kuhnle GGC, Santé-Lhoutellier V, Sayd T, Viala D, Blot A, Meunier N, Schlich P, Attaix D, Guéraud F, Scislowski V, Corpet DE, Pierre FHF.

Cancer Prev Res (Phila). 2018 Sep;11(9):569-580. doi: 10.1158/1940-6207.CAPR-17-0361. Epub 2018 Jun 28.


Application of the key characteristics of carcinogens in cancer hazard identification.

Guyton KZ, Rusyn I, Chiu WA, Corpet DE, van den Berg M, Ross MK, Christiani DC, Beland FA, Smith MT.

Carcinogenesis. 2018 Apr 5;39(4):614-622. doi: 10.1093/carcin/bgy031.


Red Wine and Pomegranate Extracts Suppress Cured Meat Promotion of Colonic Mucin-Depleted Foci in Carcinogen-Induced Rats.

Bastide NM, Naud N, Nassy G, Vendeuvre JL, Taché S, Guéraud F, Hobbs DA, Kuhnle GG, Corpet DE, Pierre FH.

Nutr Cancer. 2017 Feb-Mar;69(2):289-298. doi: 10.1080/01635581.2017.1263745. Epub 2017 Jan 17.


A central role for heme iron in colon carcinogenesis associated with red meat intake.

Bastide NM, Chenni F, Audebert M, Santarelli RL, Taché S, Naud N, Baradat M, Jouanin I, Surya R, Hobbs DA, Kuhnle GG, Raymond-Letron I, Gueraud F, Corpet DE, Pierre FH.

Cancer Res. 2015 Mar 1;75(5):870-9. doi: 10.1158/0008-5472.CAN-14-2554. Epub 2015 Jan 15.


Antibiotic suppression of intestinal microbiota reduces heme-induced lipoperoxidation associated with colon carcinogenesis in rats.

Martin OC, Lin C, Naud N, Tache S, Raymond-Letron I, Corpet DE, Pierre FH.

Nutr Cancer. 2015;67(1):119-25. doi: 10.1080/01635581.2015.976317. Epub 2014 Dec 16.


Epidemiological evidence for the association between red and processed meat intake and colorectal cancer.

Corpet DE, De Smet S, Demeyer D.

Meat Sci. 2014 Oct;98(2):115. doi: 10.1016/j.meatsci.2014.05.008. Epub 2014 May 17. No abstract available.


The role of red and processed meat in colorectal cancer development: a perspective.

Oostindjer M, Alexander J, Amdam GV, Andersen G, Bryan NS, Chen D, Corpet DE, De Smet S, Dragsted LO, Haug A, Karlsson AH, Kleter G, de Kok TM, Kulseng B, Milkowski AL, Martin RJ, Pajari AM, Paulsen JE, Pickova J, Rudi K, Sødring M, Weed DL, Egelandsdal B.

Meat Sci. 2014 Aug;97(4):583-96. doi: 10.1016/j.meatsci.2014.02.011. Epub 2014 Feb 24.


Calcium and α-tocopherol suppress cured-meat promotion of chemically induced colon carcinogenesis in rats and reduce associated biomarkers in human volunteers.

Pierre FH, Martin OC, Santarelli RL, Taché S, Naud N, Guéraud F, Audebert M, Dupuy J, Meunier N, Attaix D, Vendeuvre JL, Mirvish SS, Kuhnle GC, Cano N, Corpet DE.

Am J Clin Nutr. 2013 Nov;98(5):1255-62. doi: 10.3945/ajcn.113.061069. Epub 2013 Sep 11.


Calcium inhibits promotion by hot dog of 1,2-dimethylhydrazine-induced mucin-depleted foci in rat colon.

Santarelli RL, Naud N, Taché S, Guéraud F, Vendeuvre JL, Zhou L, Anwar MM, Mirvish SS, Corpet DE, Pierre FH.

Int J Cancer. 2013 Dec 1;133(11):2533-41. doi: 10.1002/ijc.28286. Epub 2013 Jun 21.


Heme-induced biomarkers associated with red meat promotion of colon cancer are not modulated by the intake of nitrite.

Chenni FZ, Taché S, Naud N, Guéraud F, Hobbs DA, Kunhle GG, Pierre FH, Corpet DE.

Nutr Cancer. 2013;65(2):227-33. doi: 10.1080/01635581.2013.749291.


Induction of colonic aberrant crypts in mice by feeding apparent N-nitroso compounds derived from hot dogs.

Davis ME, Lisowyj MP, Zhou L, Wisecarver JL, Gulizia JM, Shostrom VK, Naud N, Corpet DE, Mirvish SS.

Nutr Cancer. 2012;64(2):342-9. doi: 10.1080/01635581.2012.650777. Epub 2012 Jan 31.


Red meat and colon cancer: should we become vegetarians, or can we make meat safer?

Corpet DE.

Meat Sci. 2011 Nov;89(3):310-6. doi: 10.1016/j.meatsci.2011.04.009. Epub 2011 Apr 17. Review.


Heme iron from meat and risk of colorectal cancer: a meta-analysis and a review of the mechanisms involved.

Bastide NM, Pierre FH, Corpet DE.

Cancer Prev Res (Phila). 2011 Feb;4(2):177-84. doi: 10.1158/1940-6207.CAPR-10-0113. Epub 2011 Jan 5.


Calcium carbonate suppresses haem toxicity markers without calcium phosphate side effects on colon carcinogenesis.

Allam O, Bahuaud D, Taché S, Naud N, Corpet DE, Pierre FH.

Br J Nutr. 2011 Feb;105(3):384-92. doi: 10.1017/S0007114510003624. Epub 2010 Dec 7.


Freeze-dried ham promotes azoxymethane-induced mucin-depleted foci and aberrant crypt foci in rat colon.

Pierre FH, Santarelli RL, Allam O, Tache S, Naud N, Gueraud F, Corpet DE.

Nutr Cancer. 2010;62(5):567-73. doi: 10.1080/01635580903532408.


Meat processing and colon carcinogenesis: cooked, nitrite-treated, and oxidized high-heme cured meat promotes mucin-depleted foci in rats.

Santarelli RL, Vendeuvre JL, Naud N, Taché S, Guéraud F, Viau M, Genot C, Corpet DE, Pierre FH.

Cancer Prev Res (Phila). 2010 Jul;3(7):852-64. doi: 10.1158/1940-6207.CAPR-09-0160. Epub 2010 Jun 8.


Dehydroalanine and lysinoalanine in thermolyzed casein do not promote colon cancer in the rat.

Corpet DE, Taché S, Archer MC, Bruce WR.

Food Chem Toxicol. 2008 Sep;46(9):3037-42. doi: 10.1016/j.fct.2008.06.002. Epub 2008 Jun 10.


Processed meat and colorectal cancer: a review of epidemiologic and experimental evidence.

Santarelli RL, Pierre F, Corpet DE.

Nutr Cancer. 2008;60(2):131-44. doi: 10.1080/01635580701684872. Review.


Beef meat promotion of dimethylhydrazine-induced colorectal carcinogenesis biomarkers is suppressed by dietary calcium.

Pierre F, Santarelli R, Taché S, Guéraud F, Corpet DE.

Br J Nutr. 2008 May;99(5):1000-6. Epub 2007 Oct 22.


Chemoprevention of aberrant crypt foci in the colon of rats by dietary onion.

Taché S, Ladam A, Corpet DE.

Eur J Cancer. 2007 Jan;43(2):454-8. Epub 2006 Dec 26.


New marker of colon cancer risk associated with heme intake: 1,4-dihydroxynonane mercapturic acid.

Pierre F, Peiro G, Taché S, Cross AJ, Bingham SA, Gasc N, Gottardi G, Corpet DE, Guéraud F.

Cancer Epidemiol Biomarkers Prev. 2006 Nov;15(11):2274-9.


Polyethylene glycol and prevalence of colorectal adenomas.

Dorval E, Jankowski JM, Barbieux JP, Viguier J, Bertrand P, Brondin B, Bougnoux P, Corpet DE; Association Gastro 37.

Gastroenterol Clin Biol. 2006 Oct;30(10):1196-9.


Polyethylene glycol, unique among laxatives, suppresses aberrant crypt foci, by elimination of cells.

Taché S, Parnaud G, Van Beek E, Corpet DE.

Scand J Gastroenterol. 2006 Jun;41(6):730-6.


Impact of residual and therapeutic doses of ciprofloxacin in the human-flora-associated mice model.

Perrin-Guyomard A, Poul JM, Corpet DE, Sanders P, Fernández AH, Bartholomew M.

Regul Toxicol Pharmacol. 2005 Jul;42(2):151-60.


Meat and cancer: haemoglobin and haemin in a low-calcium diet promote colorectal carcinogenesis at the aberrant crypt stage in rats.

Pierre F, Taché S, Petit CR, Van der Meer R, Corpet DE.

Carcinogenesis. 2003 Oct;24(10):1683-90. Epub 2003 Aug 1.


Ranking chemopreventive agents on rat colon carcinogenesis.

Corpet DE, Taché S.

IARC Sci Publ. 2002;156:381-4. No abstract available.


Evaluation of residual and therapeutic doses of tetracycline in the human-flora-associated (HFA) mice model.

Perrin-Guyomard A, Cottin S, Corpet DE, Boisseau J, Poul JM.

Regul Toxicol Pharmacol. 2001 Oct;34(2):125-36.


Cytostatic effect of polyethylene glycol on human colonic adenocarcinoma cells.

Parnaud G, Corpet DE, Gamet-Payrastre L.

Int J Cancer. 2001 Apr 1;92(1):63-9.


Carrageenan gel and aberrant crypt foci in the colon of conventional and human flora-associated rats.

Taché S, Peiffer G, Millet AS, Corpet DE.

Nutr Cancer. 2000;37(2):193-8.


Pluronic F68 block polymer, a very potent suppressor of carcinogenesis in the colon of rats and mice.

Parnaud G, Taché S, Peiffer G, Corpet DE.

Br J Cancer. 2001 Jan 5;84(1):90-3.


Consistent and fast inhibition of colon carcinogenesis by polyethylene glycol in mice and rats given various carcinogens.

Corpet DE, Parnaud G, Delverdier M, Peiffer G, Taché S.

Cancer Res. 2000 Jun 15;60(12):3160-4.


Urinary and biliary metabolic patterns of chlorothalonil in germ-free and conventional rats.

Hillenweck A, Corpet DE, Killeen JC Jr, Bliss M Jr, Cravedi JP.

J Agric Food Chem. 1999 Jul;47(7):2898-903.


Dextran sulfate enhances the level of an oxidative DNA damage biomarker, 8-oxo-7,8-dihydro-2'-deoxyguanosine, in rat colonic mucosa.

Tardieu D, Jaeg JP, Cadet J, Embvani E, Corpet DE, Petit C.

Cancer Lett. 1998 Dec 11;134(1):1-5.


Effect of meat (beef, chicken, and bacon) on rat colon carcinogenesis.

Parnaud G, Peiffer G, Taché S, Corpet DE.

Nutr Cancer. 1998;32(3):165-73.


Ex vivo gastrointestinal biotransformation of chlorothalonil in the germ-free and conventional rat.

Hillenweck A, Corpet DE, Killeen JC Jr, Bliss M Jr, Cravedi JP.

Xenobiotica. 1998 Nov;28(11):1017-28.


[Colorectal cancer: controversial role of meat consumption].

Parnaud G, Corpet DE.

Bull Cancer. 1997 Sep;84(9):899-911. Review. French.


Cooked casein promotes colon cancer in rats, may be because of mucosal abrasion.

Corpet DE, Chatelin-Pirot V.

Cancer Lett. 1997 Mar 19;114(1-2):89-90. No abstract available.


Carrageenan given as a jelly, does not initiate, but promotes the growth of aberrant crypt foci in the rat colon.

Corpet DE, Taché S, Preclaire M.

Cancer Lett. 1997 Mar 19;114(1-2):53-5. No abstract available.


Carborundum, a bulk similar to dietary fibers but chemically inert, does not decrease colon carcinogenesis.

Corpet DE, Taché S, Peiffer G.

Cancer Lett. 1997 Mar 19;114(1-2):35-8.


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