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Items: 14


Identification of the kinase STK25 as an upstream activator of LATS signaling.

Lim S, Hermance N, Mudianto T, Mustaly HM, Mauricio IPM, Vittoria MA, Quinton RJ, Howell BW, Cornils H, Manning AL, Ganem NJ.

Nat Commun. 2019 Apr 4;10(1):1547. doi: 10.1038/s41467-019-09597-w.


The kinases NDR1/2 act downstream of the Hippo homolog MST1 to mediate both egress of thymocytes from the thymus and lymphocyte motility.

Tang F, Gill J, Ficht X, Barthlott T, Cornils H, Schmitz-Rohmer D, Hynx D, Zhou D, Zhang L, Xue G, Grzmil M, Yang Z, Hergovich A, Hollaender GA, Stein JV, Hemmings BA, Matthias P.

Sci Signal. 2015 Oct 6;8(397):ra100. doi: 10.1126/scisignal.aab2425.


Chromothripsis from DNA damage in micronuclei.

Zhang CZ, Spektor A, Cornils H, Francis JM, Jackson EK, Liu S, Meyerson M, Pellman D.

Nature. 2015 Jun 11;522(7555):179-84. doi: 10.1038/nature14493. Epub 2015 May 27.


Calibrating genomic and allelic coverage bias in single-cell sequencing.

Zhang CZ, Adalsteinsson VA, Francis J, Cornils H, Jung J, Maire C, Ligon KL, Meyerson M, Love JC.

Nat Commun. 2015 Apr 16;6:6822. doi: 10.1038/ncomms7822.


Cytokinesis failure triggers hippo tumor suppressor pathway activation.

Ganem NJ, Cornils H, Chiu SY, O'Rourke KP, Arnaud J, Yimlamai D, Théry M, Camargo FD, Pellman D.

Cell. 2014 Aug 14;158(4):833-848. doi: 10.1016/j.cell.2014.06.029.


Downstream of human NDR kinases: impacting on c-myc and p21 protein stability to control cell cycle progression.

Cornils H, Kohler RS, Hergovich A, Hemmings BA.

Cell Cycle. 2011 Jun 15;10(12):1897-904. Epub 2011 Jun 15. Review.


Human NDR kinases control G(1)/S cell cycle transition by directly regulating p21 stability.

Cornils H, Kohler RS, Hergovich A, Hemmings BA.

Mol Cell Biol. 2011 Apr;31(7):1382-95. doi: 10.1128/MCB.01216-10. Epub 2011 Jan 24.


Differential NDR/LATS interactions with the human MOB family reveal a negative role for human MOB2 in the regulation of human NDR kinases.

Kohler RS, Schmitz D, Cornils H, Hemmings BA, Hergovich A.

Mol Cell Biol. 2010 Sep;30(18):4507-20. doi: 10.1128/MCB.00150-10. Epub 2010 Jul 12.


Ablation of the kinase NDR1 predisposes mice to the development of T cell lymphoma.

Cornils H, Stegert MR, Hergovich A, Hynx D, Schmitz D, Dirnhofer S, Hemmings BA.

Sci Signal. 2010 Jun 15;3(126):ra47. doi: 10.1126/scisignal.2000681.


The MST1 and hMOB1 tumor suppressors control human centrosome duplication by regulating NDR kinase phosphorylation.

Hergovich A, Kohler RS, Schmitz D, Vichalkovski A, Cornils H, Hemmings BA.

Curr Biol. 2009 Nov 3;19(20):1692-702. doi: 10.1016/j.cub.2009.09.020.


Anchoring of FLT3 in the endoplasmic reticulum alters signaling quality.

Schmidt-Arras D, Böhmer SA, Koch S, Müller JP, Blei L, Cornils H, Bauer R, Korasikha S, Thiede C, Böhmer FD.

Blood. 2009 Apr 9;113(15):3568-76. doi: 10.1182/blood-2007-10-121426. Epub 2009 Feb 9.


NDR kinase is activated by RASSF1A/MST1 in response to Fas receptor stimulation and promotes apoptosis.

Vichalkovski A, Gresko E, Cornils H, Hergovich A, Schmitz D, Hemmings BA.

Curr Biol. 2008 Dec 9;18(23):1889-95. doi: 10.1016/j.cub.2008.10.060.


Nuclear Dbf2-related protein kinases (NDRs) in isolated cardiac myocytes and the myocardium: activation by cellular stresses and by phosphoprotein serine-/threonine-phosphatase inhibitors.

Fuller SJ, Pikkarainen S, Tham el L, Cullingford TE, Molkentin JD, Cornils H, Hergovich A, Hemmings BA, Clerk A, Sugden PH.

Cell Signal. 2008 Aug;20(8):1564-77. doi: 10.1016/j.cellsig.2008.04.013. Epub 2008 May 1.


Mammalian NDR protein kinases: from regulation to a role in centrosome duplication.

Hergovich A, Cornils H, Hemmings BA.

Biochim Biophys Acta. 2008 Jan;1784(1):3-15. Epub 2007 Aug 15. Review.


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